Conserved Protein Domain Family
CYCLIN_CABLES2
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cd20603: CYCLIN_CABLES2 
cyclin box found in CDK5 and ABL1 enzyme substrate 2 (CABLES2)
CABLES2, also called interactor with CDK3 2 (Ik3-2), acts as a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. CABLES2 contains one cyclin box. The cyclin box is a protein binding domain.
Links
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Statistics
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PSSM-Id: 410306
Aligned: 6 rows
Threshold Bit Score: 237.858
Created: 11-Jun-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9BTV7       357 LTLSKIRSLKREMRSLSEECsLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVTQLIDKLEE 436 human
PWA24319     466 LTLSKIRSLKREMRLVGEDCgLQPVTVAMAFVYFEKLVLQGRLNKQNRKLVSAACILLAAKISSDLKKHEVKQLIDKLEE 545 western mosquit...
NP_001107961 327 LTLSKIRSLKREMRNVAKECnLEPVTVAMSYVYFEKLVLQGRVNKQNRKLCAGACVLLAAKISSDFKKPELKHLLDKLEE 406 tropical clawed...
XP_014344219 182 LTLSKIRSLKREMRNVARECdLEPVTVAMGYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLKKHEVKHLIDKLEE 261 coelacanth
POI26972     152 LTLSKIRSLKREMRNLSEECnLEPVTVSMAYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLRKHEVKHLIDKLEE 231 Chinese bamboo-...
XP_007882807 188 LTLSKIRSLKREMRNLAEECnLEPCTVALSFVYFEKLVLQGKVNKQNRKLCSGACLLLAAKISSDLKKHEVKHLIDKLEE 267 elephant shark

Q9BTV7       437 RFRfNRRDLIGFEFTVLVALELALYLPenQVLPHYRRLTQQ 477 human
PWA24319     546 RFRiSRKELISFEFIILVALEMALYLPesKVLPHYRRLMQQ 586 western mosquitofish
NP_001107961 407 RFRaNRRDLVAFELTVLVAMELALYLPeaHVLPHFRRLTRQ 447 tropical clawed frog
XP_014344219 262 KFRlNRRELTAFEFTVLVALEMTLYLPeiQVLPHFRRLIQQ 302 coelacanth
POI26972     232 RFRfNRRDLIGFEFTVLVALELALYLPenQVLPHYRRLTQQ 272 Chinese bamboo-partridge
XP_007882807 268 RLRlNSKELVSFEFATLVALEFGLYLPgkKVFPHYRRLVQQ 308 elephant shark
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