6YJ4


Conserved Protein Domain Family
NI9M

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cd22903: NI9M 
Click on image for an interactive view with Cn3D
NADH:Ubiquinone Oxidoreductase, N9IM subunit
NI9M is a subunit of the NADH:ubiquinone oxidoreductase (Respiratory complex I), which is a redox-driven proton pump that plays an important role in creating the electrochemical gradient that powers mitochondrial adenosine triphosphate synthesis. NI9M is a single-pass membrane protein and a fungal subunit homologous to NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) that is considered an accessory subunit.
Statistics
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PSSM-Id: 438578
Aligned: 78 rows
Threshold Bit Score: 62.5243
Created: 22-Feb-2021
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
oligomer
Conserved site includes 40 residues -Click on image for an interactive view with Cn3D
Feature 1:oligomer interface [polypeptide binding site]
Evidence:
  • Structure:6YJ4; Yarrowia lipolytica NI9M subunit of protein NADH:Ubiquinone Oxidoreductase (Complex I) interacts with other subunits of the complex, contacts 4A
  • Comment:NI9M subunit interacts with chains 1, 3 and 6 and the subunits Nb6M, NucM, NufM, NuiM, NunM, NupM and NuxM.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          #  ## ### ##  ##  ##  ## ##      ##    # ############ #          ## ######
6YJ4_b        12 PFRYLRWSAHNRPHLFFAFAIGIAGPVAALtLTPLRRKYl-YPDHSPLPQSYPLPQRa---------REQLTGFDD 77  Yarrowia lipolytica
RMZ83678      12 PVRYVRWAFYQKPAIAYAVAIGSIAPTIPFwVPPLRRAVg-DEKVPYVPHSYPVPTGp---------RKRPAGFED 77  Chaetothyriales sp....
GAD91661      10 PLRYLRWASYEKPAIFYSILIGSMGPVALVtLPPIRRLLg-DVDPEPIPLTYPNKLTc--------gFRDIQFPRA 76  Byssochlamys specta...
XP_016210413  15 PLRYMRWAARERPALFWSCVVGGAGPLIVVaAPPLRARFfnDYRPPPIPSTYPIPAGp---------RKIPSGYED 81  Verruconis gallopava
P42117        12 PFRYIRWSAREKPAYFYSCVIAGLGPVFLTvVPPVRKYFg-DVNPAPIPVTYPIPTGp---------RKQLTGYDD 77  Neurospora crassa O...
XP_001904999  12 PLKYCRWAARERPSLFWSCVIAGFGPLHLIvVPPVRRALg-DYDAPQIPMTYPGANYaeeevdgirgRDGVMGRDE 86  Podospora anserina ...
PHH54083      12 PLTFMRWAIRERPAYFWSLAIGALGPAFIVaVPPLRQAVg-DVNAARIPVTYPIPTGp---------RKQLTGFDD 77  Ceratocystis fimbri...
OQO25656      10 PTTYIHWAARAKPAIFWSIVIGCMGPLTLIvVPPLRERLg-DPMRSQIPLTYPIPRGr---------RQIPSGYDD 75  Rachicladosporium s...
XP_008717267  12 PVRYLRWAMHEKPAIFFSIVVGSMGPPLLYtLPSIRARFg-DFDPPAVPHSYPVPKGp---------RKVPEGFDD 77  Cyphellophora europ...
XP_018001555  12 PLRYIRWAFHEKPAIAWSMVLGGMGPPLLYaLPKVRRRFg-DEDPPEVPHSYPAPISag------rnPFDPAHEED 80  Phialophora attinorum

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