Conserved Protein Domain Family
DUF4225

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pfam13988: DUF4225 
Protein of unknown function (DUF4225)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 182 and 282 amino acids in length.
Statistics
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PSSM-Id: 433629
Aligned: 11 rows
Threshold Bit Score: 187.919
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013316609    68 EEIRKERESTEKEYQRLRTGDYIKYIVTDI----------FEDQGVLKYVKIASGVVSGGFQTFAGYKLNqfGKTFHIKH 137 Dickeya dadantii
WP_024911829    76 VCLKAEHNSLRMQYESLQLNKAAKAVYLEI----------KKENGIYTYVVKAVGVVAGISQLASGIAMV--IASQVTVV 143 Chania multit...
WP_024913650    76 VRLKAESDSLRMQYESLQLNKTVKAVYLEI----------KKDNGYLTYVIKGIGVIAGLSQLIAGIPMA--FGSAVTGV 143 Chania multit...
Q7N2U7          68 YAVKDEYEITEKEYQALRRKDYTKYIVTDI----------FEDQGVVKYAKIGGGVVAGIAQTAAGIAVInsGRIVRSKR 137 Photorhabdus ...
Q7N2C9          67 AILQDEIDNLKRQEFDLLMNDSQIYMIVQK----------EEEDEKTNLTLKRIGFVSGGSQIFAGLGVC---VASLGAA 133 Photorhabdus ...
Q7NAC8          62 EIIQFEIDHLKEQAFCLTANRVKQYAIIERe---------KEKSSYTNLILKQIGFVGGGTQILAGYTVC---KASLGLA 129 Photorhabdus ...
ADD77874        75 QNLKQETQNLKIQDRMLRTGEAVVSSSVQFy---------HDHEKVIGYVIDGIGVVLSGMQIVAGVGLIvgSVTTGNVI 145
LANL:CH55_2730   1 ----MECYHLSKQDSMLSLKQAKVYISAKI----------EEHDKVIGYVIDGIAVIVGGLQMVAGSGILlgSIASGNIV 66 
Q6D8A6          91 NNIKEECANIEKQGTMLSLEKAKVFITISM----------EKRDKEFGYTINAIGVIVGGAQFVSGVGIA---YAATGYL 157 Pectobacteriu...
AHG20056        84 HSLDEEIASLRCQDEMIARKQLKQVVIVKPvldpviknrtTKRQENISLIIAGVGFVSGALQFVAGVGLV------ETGV 157
WP_002211601    90 KLLDKELSDLRNQDEEMTRERVKQAVIIKAsvke---nnnVERNEVINLVFAGVGFVTAGLQIVAGVGMV------GSVV 160 Yersinia pestis
WP_013316609   138 FKSFGILLIAHGANNMYEAASPLFnDGIHKSGTLRNIYRYITNS-FGYNNDDGDLLYSAGDLSLTLYAAFRTpvlfenpn 216 Dickeya dadantii
WP_024911829   144 SGVTGVLLICHGTNNIYENAQYFF-TGEEHTGYLRDLYRWTSTN-VGYGEHGGDILYAGMDLSLSLRALFGK-------- 213 Chania multit...
WP_024913650   144 SAGLGVLLIAHGSNNVYENGQYFF-TGEERTGLVRDLYRYASNK-AGYSDNSADIIYAGIDLSLSAKILFGK-------- 213 Chania multit...
Q7N2U7         138 VQLMGAVLVAHGGSNFYEAISPIL-YENQKIGLVRKGYRYASHA-LGYGDDVADVAYSSVDLVASLYGTYGVlklkpvks 215 Photorhabdus ...
Q7N2C9         134 CAGFGVPLLIQGGNNVYENGYYLL-LRKEVSGPVRDVYRDAAKT-LGYSETDGDRVYGYVDLALSGYGMARS-------- 203 Photorhabdus ...
Q7NAC8         130 CASFGAPLMAHGYNNVVENGYYLL-YRENINGGVREGYRYVANK-IGLSDKDADITYATVDLVLSGYGIFRK-------- 199 Photorhabdus ...
ADD77874       146 GVVAGSALVMNGVGSGIESIGKLS-GVPHPSNPVRDKYEDAADF-LGFDKRLGLLTYQVVDLTTSYYGLFKL-------- 215
LANL:CH55_2730  67 GIIVGAHLILNGASSLSEGVQRLR-GNKNTTGFMQDAYMGTAEF-FGFERKTGMLAYYAADLTTSFYGVIKL-------- 136
Q6D8A6         158 GRFIGAHIALNGASSLSESIFHLI-GREDSVGFMKSGYVRTAEF-LGFDKRSGLLAYHSVDLVTSFYGIVKL-------- 227 Pectobacteriu...
AHG20056       158 GAGMGGLLIGHGINNVVENGYYLL-YRENYTGPVKFVYEQVGQNiFGLNTRDSDVIYTFVDMGISVNVLLGY-------- 228
WP_002211601   161 GSIPGTLLILHGANNIVESGYYIL-YRESYTGPVKFVYEGVGAQ-FGLSKSDSAIMYTAVDVALSINGIMSY-------- 230 Yersinia pestis
WP_013316609   217 -rlvskgfMDSP-------------RAIKLFYYVNKDHISKFSSAS 248 Dickeya dadantii
WP_024911829   214 --------VLVPngrsllgisgrgvDTERLFYAMYNDSVTGFKTMG 251 Chania multitudinisentens
WP_024913650   214 --------VAVSnansll-gsanrsDTGRLFRAVNKDMLVGFKAMS 250 Chania multitudinisentens
Q7N2U7         216 knnisggySVKP-------------GTGKLFRYINSDLARKWQLTP 248 Photorhabdus laumondii subsp. laumondii
Q7N2C9         204 --------VVRP-------------GTFRLFRYIKTDYIRGWQVMG 228 Photorhabdus laumondii subsp. laumondii
Q7NAC8         200 --------VLKPr-----------eKSWSLFRNINSDFIRGWREMG 226 Photorhabdus laumondii subsp. laumondii
ADD77874       216 --------TLKP-------------EAWRLYKYLPTDHYRKVQLLS 240
LANL:CH55_2730 137 --------SLKP-------------DAWRLYKYIPSDYYRKINSMS 161
Q6D8A6         228 --------TLKP-------------DAWRLFRYIPSDYYRKINTMS 252 Pectobacterium atrosepticum
AHG20056       229 --------RLEP-------------DMSRLLRYVNADLLTGLKHPG 253
WP_002211601   231 --------KLAE-------------DATRLYRYVNADLLWGLKSMD 255 Yersinia pestis
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