Conserved Protein Domain Family
C-C_Bond_Lyase

?
pfam15617: C-C_Bond_Lyase 
C-C_Bond_Lyase of the TIM-Barrel fold
This family of TIM-Barrel fold C-C bond lyase is related to citrate-lyase. These genes are found in the biosynthetic operon, with other enzymatic domains, associated with the Ter stress response operon and are predicted to be involved in the biosynthesis of a ribo-nucleoside involved in stress response.
Statistics
?
PSSM-Id: 406131
Aligned: 67 rows
Threshold Bit Score: 308.721
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_003969407  30 RMLSVALGATLYSPATRPSLADDVLKQAARGVVSMVLCLEDSIDDAEVIGAESNLIRQFAELAARDAAagpegrtegtaa 109 Streptomyces
1_pfamImport   1 RLSPWNLGATLYMPATREDIADAVLHGKIPGLRSLVICLEDAVSEADIPIALKNLEHLLHELSNSMRSlg---------- 70 
WP_000797366   4 RLSPWNLGATLYMPATREDIADAVLHGKIPGLRSLVICLEDAVSEADIPVALKNLEHLLHELSNSMHSlg---------- 73  Enterobacterales
WP_012124739   4 RLSPWNLGATLYMPATREDIADAVLNGKIPGLRSLVICLEDAVSEADIPVALKNLGQLLHELSNSMLSlg---------- 73  Cronobacter
4_pfamImport   1 TPSAYALGATLYMPATRTDIADIIIHNKISGLRSLVICLEDAVSEDDVPLAISQLSTLLGTLAVEKKRdg---------- 70 
WP_012988270   4 IPSPHQLGATLYIPATRQGIAEIVLHNKIPGLRSLVICLEDAVSDQDIPAAIENLDGVLQSLAGADISssh--------- 74  Xenorhabdus bov...
WP_013184744   4 IPSPHQLGATLYMPATRQDIAEIVLQNKIVGLRSLVICLEDAVSERDIPAAIDNLGGVLQILAEAGVRhagkq------- 76  Xenorhabdus nem...
Q6FAX8         1 MLSALSLGATLYIPATRPDLWPIVTGEKYPELRSLVICLEDAITEQDVELAKQNLKQLLQKIQQQQWHe----------- 69  Acinetobacter b...
WP_011959381  17 PLHPYQLGASLYMPATREDIWAVISRSKLPNLDSVIICLEDAVSESDVPYAWSNIQKLLSHWASVQQDtplsvsrsqcvn 96  Psychrobacter s...
Q4FTQ0        59 MHHPYQLGASLYMPATRQDIWQVIKRDKLPTINSIIICLEDAVSHNDVEVALERLQILLHTWATHVDSineptqq----- 133 Psychrobacter a...
WP_003969407 110 ----rdphgttdaagADVPLLFVRVREPAQIVDLVRRLgdSVRMLSGFVLPKFTEDRGKPFLEALAE--AEsecgrrLFA 183 Streptomyces
1_pfamImport  71 --------------kNDWPLVFIRPRHADMGRWLKAHY--DLSAVDGFVLPKFTLSSLAEWWDIMGG--TH------LCM 126
WP_000797366  74 --------------kNDWPLVFIRPRHAEMGRWLKAHY--DLSAVDGFVLPKFTLSSLAEWWDIMGG--TH------LCM 129 Enterobacterales
WP_012124739  74 --------------kNDWPLVFIRPRHAEMGKWLKEHY--DLSAVDGFVLPKFTLSSLAEWWDIMGE--TH------LCM 129 Cronobacter
4_pfamImport  71 --------------sAHWPLIFVRPRHEAMGLALITRF--NLSAINGFVLPKFTQASITTWWEIMKE--TH------LCM 126
WP_012988270  75 -------------teRDYPLIFIRPRNEEMGRYLVDNV--NLSAVDGLVLPKFTRASLAGWWNIVGS--TH------LSM 131 Xenorhabdus bov...
WP_013184744  77 ----------vsdtkRHHPLLFIRPRNEMMAKQLITNV--NLNAIDGLVLPKFTCASLPGWWEIIRS--TH------LCM 136 Xenorhabdus nem...
Q6FAX8        70 ----------------QHPKVFIRPRHIAMAAELAEWQ--EITALDGMVLPKFGLANFKQWLDVLPA--TL------HY- 122 Acinetobacter b...
WP_011959381  97 qideatgvqisavqkSNRPLVFIRPRNPQMLMQLAALP--NINLVDGYVLPKVDMDSLSNWRLACQQvqED------SLL 168 Psychrobacter s...
Q4FTQ0       134 --------adiqpeqPTRPLVFVRPRHPVMLEQLSNFS--HIDLIDGFVMPKVDMYSLSNWRMACQNlsTN------MLL 197 Psychrobacter a...
WP_003969407 184 MPVLESPELLhletRGEILRGIARSVEKH--RDRVLALRLGVTDFCSAYGLRRAPDMTAYDvHIVASVIADVVNVLGRAd 261 Streptomyces
1_pfamImport 127 MPTLETEDVF----DVVQMRELATRLVEHpcHDRIIALRIGGNDLMNVVSLRRPRDLTLYD-SPMGYVIKMLVSVFGPR- 200
WP_000797366 130 MPTLETEDVF----DVVQMRELATRLVEHpcHDRIIALRIGGNDLMNVVSLRRPRDLTLYD-SPMGYVIKMLVSVFGPR- 203 Enterobacterales
WP_012124739 130 MPTLETEDVF----DVVQMRELATRLVEHpcHERIIALRIGGNDLMNVVSLRRPRDLTLYD-SPMGYVIKMLVSVFGPR- 203 Cronobacter
4_pfamImport 127 MPTLETEDVF----DVAKMSTLARELENHpsRQRIVALRIGGNDLMSVISMRRSRKLTLYD-GPMGYVIKMLVSVFCPK- 200
WP_012988270 132 MPTLETEEVF----DSRQLNQLADSLKAHpcYKRIIALRIGGNDLMNVISLRRSRDFTLYE-GPMGYVIKMLVTIFAAR- 205 Xenorhabdus bov...
WP_013184744 137 MPTLETKEVF----DVQKMNQLADILKAHpcEARIIALRIGGNDLMNVMSLRRPRDFTLYD-GPMGYVIKMLVAVFAAR- 210 Xenorhabdus nem...
Q6FAX8       123 MPTLETADSF----DMEQMKELRQALPE---FHKVLVLRIGGNDLLNCLALRRPSDVTLYQ-TPIGTLIANLAGQFLPY- 193 Acinetobacter b...
WP_011959381 169 MPTLETGRLF----DPAHNQALATALAHa-fDERVFALRIGGNDLFSALRLRRPSTQTIYE-TPVGTLMHQLIGTFVPQ- 241 Psychrobacter s...
Q4FTQ0       198 MPTLETAALF----NPHHNQELAIGFKEa-fSQPVFALRIGGNDLFAALRLRRPKNSLVYD-TPVGTLAYQLLGCFVPH- 270 Psychrobacter a...
WP_003969407 262 gtGFTITGPVWEYFRRQErmfkpqlrrspflegraeelrtaliehdldGLLREIELDRANGLLGKTCIHPSHVAPVHALS 341 Streptomyces
1_pfamImport 201 --DFALTAPVCEHIDDHA------------------------------VMARELALDMAHGLVGKTAIHPGQIEVIQNAL 248
WP_000797366 204 --DFALTAPVCEHIDDHA------------------------------VMARELALDMAHGLVGKTAIHPGQIEVIQNAL 251 Enterobacterales
WP_012124739 204 --DFALTAPVCEHIDDHA------------------------------VMARELALDMANGLVGKTAIHPGQIEVIQNAL 251 Cronobacter
4_pfamImport 201 --NFALTAPVCEQIDNPQ------------------------------LLETELALDIAHGLVGKTAIHPSQIEVIQRAL 248
WP_012988270 206 --GFSLTAPVCEHIDDLR------------------------------LLEKELVLDIAHGLVGKTAIHPGQIEYIQRAL 253 Xenorhabdus bov...
WP_013184744 211 --GFALTAPVCEHIDDLK------------------------------LLEKELTLDITHGLVGKTAIHPRQIACIHQAL 258 Xenorhabdus nem...
Q6FAX8       194 --GFALSAPVCEHFSQVK------------------------------LLQDELYLDLQYGLSGKTVIHPAQISIVHQAY 241 Acinetobacter b...
WP_011959381 242 --GYYLTAPVCEYFDNTA------------------------------LFIQELATDVSLGLVGKTVIHPAQIALVQQAF 289 Psychrobacter s...
Q4FTQ0       271 --GFYLSAPVFEYLDEPT------------------------------LFMQELTRDVSLGLVGKTVIHPSQIALVQQAY 318 Psychrobacter a...
WP_003969407 342 VVSHEEYTDAQDILSP-ERgggGVLRSAytNKMNEVKPHRAWAERTLQRAEVFGV 395 Streptomyces
1_pfamImport 249 MVTQGEHSDALRILNS-TQ---AVFKSQ--GAMCEPATHRRWAAGILDRARFYGL 297
WP_000797366 252 MVTQGEHSDALRILNS-TQ---AVFKSQ--GAMCEPATHRRWAAGILDRARFYGL 300 Enterobacterales
WP_012124739 252 MVTQGEHSDALRILNS-TQ---AVFKSQ--GAMCEPATHRRWAAGILDRARFYGL 300 Cronobacter
4_pfamImport 249 MVDTHDHADALRILNS-TQ---AVFKSQ--GAMCEPSTHKRWAAAILERAQYYGI 297
WP_012988270 254 MVNGHDYADALRILNS-SQ---AVFKSQ--GTMCEPATHRRWAVNILDRAKYYGI 302 Xenorhabdus bovienii
WP_013184744 259 MVSAPDYADALSILNA-KQ---AVFKSQ--GVMCEPATHQRWAMNILERAAHYGI 307 Xenorhabdus nematophila
Q6FAX8       242 QVNEIELKQAQDILQDgCK---AVFACH--GSMLEPATHRRWAERILERAKVFGL 291 Acinetobacter baylyi
WP_011959381 290 SVSTRVLEEAQAILAQdAK---AVFKHN--NTMLEPATHYAWAVQTVKRAQIFGV 339 Psychrobacter sp. PRwf-1
Q4FTQ0       319 CVPLSILDEAQAILHSeAK---AVFKYN--NTMLEPATHRAWATEIVNRAQVFGT 368 Psychrobacter arcticus
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap