Conserved Protein Domain Family
PRK06354

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PRK06354: PRK06354 
pyruvate kinase; Provisional
Statistics
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PSSM-Id: 235784
Aligned: 87 rows
Threshold Bit Score: 909.69
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
86609010    1 MHLRDSFRRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQTAMDLGIQVAILQDLQGPKIRL 80 
72382135    1 MKILDLARRTKIVATIGPATESASQISKLVEAGATTFRLNFSHGDHEEHAQRIKTIRKVSDDLGIHIGILQDLQGPKIRL 80 
78779272    1 MSNIDLKRRTKIVATIGPATQSEEIITNLIKAGVTTFRLNFSHGDHNDHAERIKTIREVSQKLDIDIGILQDLQGPKIRL 80 
159903388   1 MTNIHFKRRTKIVATIGPATESKERITELVEAGATTFRLNFSHGDHSEHAKRIETIRLVEAKLGVKIGILQDLQGPKIRL 80 
157413314   1 MSNIDLKRRTKIVATIGPATQSKEIITDLIIAGVTTFRLNFSHGDHKDHAERIKTIREVSKKLDIDIGILQDLQGPKIRL 80 
123968482   1 MSNIDLKRRTKIVATIGPATQSEEIITNLIKAGVTTFRLNFSHGDHKDHAERIKTIREVSKKLDIDIGILQDLQGPKIRL 80 
123966228   1 MSNIDLKRRTKIVATIGPATQSEEVITDLIKAGVTTFRLNFSHGDHKDHEERIKTIRKVSKNLDLDVGILQDLQGPKIRL 80 
126696285   1 MSNIDLKRRTKIVATIGPATQSEEIITNLIKAGVTTFRLNFSHGDHKDHADRIKTIREVSKKLDIDIGILQDLQGPKIRL 80 
124025674   1 MKILDLARRTKIVATIGPATESASQISKLVEAGATTFRLNFSHGDHEEHAQRIKTIRKVSDDLGIHIGILQDLQGPKIRL 80 
33240373    1 MTTIDLKRRTKIVATIGPATESPEKITELIKAGATTFRLNFSHGDHEEHAKRIKTIRSVASDLGVNIGILQDLQGPKIRL 80 
86609010   81 GKFAEGSITLKAGDPFVLTSKPVLGSQERSWVTYDKLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSN 160
72382135   81 GRFKNGPVNVKNGDKFILTSKNIDCNQDQANVTYDKLAEEVNVGNRILLDDGRVEMKVEEVDLKEQRLICSITVGGVLSN 160
78779272   81 GRFKDGPVKVKKGDKFTLTSNEVECSNTIANVTYENLSQEVSEGKRILLDDGKIEMIVEKVDTKANLLECLVTVGGVLSN 160
159903388  81 GRFKDGPIRLNSGDKFVLTSKDVGCNNEIANVTYEKLVSEVSINKRILLDDGRVEMVVERVDKLEEKLHCKVVVGGMLSN 160
157413314  81 GRFKDGPVKVKKGDKFTLTSNDVECTNTIANVTYDKLSQEISEGKRILLDDGKIEMIVEKVDLKSNNLECIVTVGGVLSN 160
123968482  81 GRFKDGPVKVKKGDKFTLTSNEVECTNTIANVTYDKLSQEVSEGKRILLDDGKIEMIVEKVDTKANNLECMVTVGGVLSN 160
123966228  81 GRFKDGPVKVKKGDKFTLTSNEVECTKSIANVTYNRLAQEVTEGKRILLDDGKIEMIVEKVDLPNNLLKCKVTVGGVLSN 160
126696285  81 GRFKDGPVKVKKGDKFTLTSNEVECTNTIANVTYEKLSQEVSEGKRILLDDGKIEMIVEKVDTKANNLECMVTVGGVLSN 160
124025674  81 GRFKNGPVNVKNGDKFILTSKNIECNQDQANVTYDKLAEEVNVGNRILLDDGRVEMKVEEVDIKEQRLICSITVGGVLSN 160
33240373   81 GRFKEGPVNLKTGDVFALTSENKDCNQEIANVTYENLVNEVEKGKRILLDDGRVEMIVENVDKKNKSLICKVTVGGILSN 160
86609010  161 NKGVNFPGVRLSIRAVTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIasakrpssGSADKRVPIIVKIEKHEAI 240
72382135  161 NKGVNFPDVQLSIRALTDKDKKDLAFGLKQGVDWVALSFVRNPSDLIEIKDLI--------RNHGYDTPVVAKIEKFEAI 232
78779272  161 NKGVNFPDVQLSVKALTEKDKEDLKFGLSEGVDWIALSFVRNPSDINEIKDLI--------NKNGHSTPVVAKIEKFEAI 232
159903388 161 NKGVNFPDVQLSINALTPKDKIDLSFGLSQSIDWVALSFVRNPDDIKEIKELI--------RSHGYTTPVVAKIEKFEAI 232
157413314 161 NKGVNFPDVQLSVKALTEKDKEDLKFGLSEGVDWIALSFVRNPSDINEIKDLI--------NKNGHSTPVVAKIEKFEAI 232
123968482 161 NKGVNFPDVQLSVKALTEKDKEDLKFGLSVGVDWIALSFVRNPSDINEIKDLI--------NTNGHSTPVVAKIEKFEAI 232
123966228 161 NKGVNFPDVQLSVKALTDKDIDDLEFGLTAGVDWIALSFVRNPSDINEIKNLI--------NKSGQSIPVIAKIEKFEAI 232
126696285 161 NKGVNFPDVQLSVKALTEKDKKDLKFGLSEGVDWIALSFVRNPSDINEIKDLI--------NKNGHSTPVVAKIEKFEAI 232
124025674 161 NKGVNFPDVQLSIRALTDKDKKDLAFGLKQGVDWVALSFVRNPSDLIEIKDLI--------RNHGYDTPVVAKIEKFEAI 232
33240373  161 NKGVNFPDVQLSINALTEKDKIDLSFGLKQGVDWVALSFVRNPADIQEIKELI--------RRHGYTTPIVAKIEKFEAI 232
86609010  241 EQLPQILALSDGVMVARGDLGVELPAEEVPILQKRVIALANSLGIPVITATQMLDSMVHSPRPTRAEISDVANAILDGTD 320
72382135  233 DQIDAVLKLCDGVMVARGDLGVEMPAEEVPLLQKQLIKKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTD 312
78779272  233 DQIDAVLPLCDGVMVARGDLGVEMPAEEVPLLQKDLIRKANSLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTD 312
159903388 233 DQIDAILRLCDGVMVARGDLGVEVPAEEVPLLQKELIKKSNSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTD 312
157413314 233 DQIDTVLPLCDGVMVARGDLGVEMPAEEVPLLQKELIRKANTLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTD 312
123968482 233 DQIDTVLPLCDGVMVARGDLGVEMPAEEVPLLQKELIRKANSLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTD 312
123966228 233 DQIDSILPLCDGVMVARGDLGVEMPAEEVPLLQKELIRKANTFGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTD 312
126696285 233 DQIDTVLPLCDGVMVARGDLGVEMPAEEVPLLQKELIRKANSLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTD 312
124025674 233 DQIDAVLKLCDGVMVARGDLGVEMPAEEVPLLQKQLIKKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTD 312
33240373  233 DQIDSILSLCDGVMVARGDLGVEMDAEEVPLLQKELIKKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTD 312
86609010  321 AVMLSNETAVGKYPVEAVATMARIAVRTERDYFDLTYADRRQrlralamqelsqnngnspagmrpkTLITDSISRAVGEI 400
72382135  313 AVMLSNETAVGDYPIESVATMATIAKRIERDYPQKALESHLP------------------------STIPNAISAAVSSI 368
78779272  313 AVMLSNETAVGDYPVEAVQTMATIARRIERDYPLKAIESHLP------------------------STIPNAISGAVSNI 368
159903388 313 AVMLSNETAVGDYPIEAVKTMATIAKRIEKDYPQRALESHLP------------------------STIPNAISAAVSSI 368
157413314 313 AVMLSNETAVGDYPVEAVETMATIARRIERDYPLKAIESHLP------------------------STIPNAISAAVSNI 368
123968482 313 AVMLSNETAVGDYPVEAVETMATIARRIERDYPLKAIESHLP------------------------STIPNAISAAVSNI 368
123966228 313 AVMLSNETAVGDYPVEAVETMATIARRIERDYPLKAIESNLP------------------------STIPNAISAAVSNI 368
126696285 313 AVMLSNETAVGDYPVEAVETMATIARRIERDYPLKAIESHLP------------------------STIPNAISAAVSNI 368
124025674 313 AVMLSNETAVGDYPIEAVATMATIAKRIERDYPQKALESHLP------------------------STIPNAISAAVSSI 368
33240373  313 AVMLSNETAVGDYPIEAVETMAKIARRIERDYPQRALESHLP------------------------STIPNAISAAVSTI 368
86609010  401 AQELDAVAVMTLTKTGATARNVSKFRPRTPILAVTPHVEVARRLQLVWGVHPLLVMDLATTRQTFQAAISLAQEDGLLKD 480
72382135  369 ARQINAAAIIPLTKSGATAKNVSKFRPPTPVLAVTNEKSVASTLQLVWGVTPLLIENQTSTSKTFDDAMNMAKKMKILKQ 448
78779272  369 ARQLDAGAIIPLTKSGSTARNVSKFRPPTPILATTTERSVARRLQLVWGVTPIVVNNDERTAKTFSLAMQIAQEMGILKQ 448
159903388 369 SRQLNASAILPLTKSGSTAHNVSKFRPPTPIVAVTNETDVARRLQLVWGVTPIVIKEQETTTKTFNLAMEMAQGMGLLKP 448
157413314 369 ARQLDAGAIIPLTKSGSTARNVSKFRPPTPILATTTERSVARRLQLVWGVTPIVVKNDERTAKTFSLAMQIAQEMGILNQ 448
123968482 369 ARQLDAGAIIPLTKSGSTARNVSKFRPPTPILATTTERSVARRLQLVWGVTPIVVKNDERTAKTFSLAMQIAQEMGILNQ 448
123966228 369 ARQLDAGAIIPLTKSGSTARNVSKFRPPTPILATTTEKSVARRLQLVWGVTPLLVKSDDRTARTFSIAMQIAQEMGILKQ 448
126696285 369 ARQLEAGAIIPLTKSGSTARNVSKFRPPTPILATTTERSVARRLQLVWGVTPIVVKNDERTAKTFSLAMQIAQEMGILNQ 448
124025674 369 ARQINAAAIIPLTKSGATAKNVSKFRPPTPVLAVTNEKSVASTLQLVWGVTPLLIENQTSTSKTFVDAMNMAKKMKILKQ 448
33240373  369 ARQLNAAAILPLTKSGATAHNVSKFRPATPILAITSEISVARRLQLVWGVSPLLIDAQKSTSKTFGIAMEQAMDMKLLKP 448
86609010  481 GDLVVLSAGTLPGVAGSTDLIKVDVVKAVVAQGKG---FGKGIVSGPARILRSSLDASKITAGDILVAQSTDANYVEAIK 557
72382135  449 GDLVVETAGTLSGVSGSTDLVKVGIVSSE-------------------------------DENESLFI------------ 485
78779272  449 GDLVVQTAGTLTGISGSTDLIKVGLVRKILSRGIS---IGEIGVTGKARKINTKLDLSLICPGEILFVNKELLENVPLSK 525
159903388 449 GALVVQTAGTITGVSGSTDLIKVGIVNDIVARGNS---EGNNSVCGKVRIAKEQKDLSELKKGEILVLDKNINNYSQALK 525
157413314 449 GDLVVQTAGTLTGISGSTDLIKVGLVRKIVSRGIS---IGEIGVTGKARIIKNNPDISLICPGEILFVPEELMKNIPLSK 525
123968482 449 GDLVVQTAGTLTGISGSTDLIKVGLVRKIVSRGIS---IGEIGVTGKARIIKNNLDISLICPGEILFVPKELMKNIPLSK 525
123966228 449 GDLVVQTAGTLTGISGSTDLIKVGLVRKVITRGIS---IGEIGVTGKARNIETSLDLSLITHGEILFVSKNLLKDLPYSK 525
126696285 449 GDLVVQTAGTLTGISGSTDLIKVGLVRRIVSRGIS---IGEIGVTGKARIIKNNLDISLICPGEILFVPKELMKNIPLSK 525
124025674 449 GDLVVETAGTLSGVSGSTDLVKVGIVSSE-------------------------------DENESLFI------------ 485
33240373  449 GDQVVETAGTLTGISGSTDLIKVGIVSKIVASGKTkpiVKEGTISGKLRVINKATDLSDLKSGEILVLAENVQYNLDTKT 528
86609010  558 QAAGVITE-EEGASSHAAVIGLRLGVPVLVGVKDA-TRLIRDGSIVTLNPEKGIVTAGADGLG 618
72382135      ---------------------------------------------------------------    
78779272  526 NIAGIVTN-QNVDDVYAFFNKNNKKISTICNVENIdNNQIINGDLVTLQLNEGVIYMGQIEDD 587
159903388 526 YAAGIILE-------GTLNIENNNTVPTIYNVKGA-TDILRDGDMVTLVLKEGTICRGEILND 580
157413314 526 NIAGIVTN-QNVNDVYALFNKNNKKISTICNLENIdNHQISNGDLITLQLNEGVIYKGQIEDD 587
123968482 526 NIAGIVTN-QNVNDVYAFFNKNNKKISTICNLENMdNHQISNGDLITLQLNEGVIYMGQIEDD 587
123966228 526 KITGIVTD-ETVDECYKIFKKNKIKISSICNLSTI-DNQVTNGDVITLQLNEGVIYMGQIEED 586
126696285 526 NIAGIVTN-QNVNDVYAFFNKNNKKISTICNLENMdSHQISNGDLITLQLNEGVIYMGQIEDD 587
124025674     ---------------------------------------------------------------    
33240373  529 HISAMIFEgEYSLINTNNQIEDNNIIPAIYNVEGA-CTKFKNGEIVTLDLKDGNIIKGLAQDL 590
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