Conserved Protein Domain Family
DUF4954

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pfam16314: DUF4954 
Domain of unknown function (DUF4954)
This family consists of uncharacterized proteins around 660 residues in length and is mainly found in various Bacteroides species. The function of this protein is unknown.
Statistics
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PSSM-Id: 435270
Aligned: 16 rows
Threshold Bit Score: 866.222
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Poras_0974   2 RKLNTKEIKQLTEQGCQAQDWSLIRVHRYFDASRCQQVHFIGKCEIGDNRGGRpsEEEPSYVEPYRLAHAKLINCTIGDR 81 
WP_038554656    10 RNLYDEEIGQLVHQGCSSSDWSLIKVSHDFIPDCIENSKFSGSVRLNSFAGSV--KLIGGINFKTGIYNAWLHNCEVGKN 87  Draconibacter...
Q7MTP4           9 RHLTEEEISVLEGNYCQCADWTMVEVADGFDANRCLHVMFSGQIRIGSTRGSH--LLPGGLHVPTGINIARLHNCIVGDE 86  Porphyromonas...
WP_013446291     5 RPLLDKEIATLTVYGCSAENWKEVQVTEEFSPSYFYNVHFSGTVFLGNYTEVF--ELAGGIKKHAGIYNCHLHNCTIGNN 82  Paludibacter ...
EHO42135         4 KSLSSAEINQLKEQGCRAEDWSAVLIHRETDLARIRFVTFKGKVAVGKLSDFI--EIEPGRVEECSLQNVTLDSTVIADE 81 
CCY34444         6 RQLTAEEISVLRTQGCWAEDWQHIYVSERFTPESIVRVNFYGVVRLGAFSGSI--ALPGGLSIHSGIYDATLFNVNVDDD 83 
WP_011967257     5 RNLRPDEIATLRSQACRADDWNQVWVPEVFDIEYVNHVRFSGVVKLGAFRKIF--TLPGGLVKHSGLRHVTLHNCTLGDN 82  Parabacteroid...
WP_006744422     5 RKLLTKEIDALKQQGCQSSNWDIIEVHPLFNAKNVHRVTFMGNIKLGLLEGTF--QLPGGVTQQSMIKDATLHNCEIGDG 82  Bacteroides c...
Q5LHM9           6 RRLTEDEVLQLKSQSCLADDWNKVAVAEEFTTEFVHHTRFSGEVKLGVFHSDF--ILPGGIKKHSGLRHVTLHNVTVGDN 83  Bacteroides f...
CCZ87291         6 RLLTKEEIARLEAQHCIASDWSGVEVADDFHTDYIHHTRFSGKVRLGVFEKEF--TLAGGMAKHSGVYYATLHNVTVGDN 83 
jgi:Poras_0974  82 VIIDGVRDCISHYDIGDDVVIHDIATLKVMGETSFGNGTLVEVLNETGGREVPICDILTAQTAYMLAMYRHDKELQAALS 161
WP_038554656    88 ALIHNVRSYIANYRIEENVVIHNITTLAVDGETSFGNGVVVEAINEGGGREIPIYDYLSTHVAYMMALYRHRPEVVRSLK 167 Draconibacter...
Q7MTP4          87 VVIFHVNSYLANYRIGDYTRIENIDTIAVTESTSFGNGVEVTVLNETGGREVTITDNLTAQTAYLMAMYRHDKVLTESLA 166 Porphyromonas...
WP_013446291    83 VFIDKINNYIANYEIGDGTYIENVNLILTEGESSFGNGIKIPVMIEAGGREIPVFDQLSAPLAYMMAFYRHDKEAVNNLE 162 Paludibacter ...
EHO42135        82 VYLNDV-GLIKNYAIGDGAAIEQVKLLSATGKTTFGNGVRIEALNEGGGREMIIFDQLSAQIAYLQTLYRHEPQLINALQ 160
CCY34444        84 ALITHIHGYIANYDIGPRVYICDVGKIYMEGVPSFGIGTRVNVLPETGGREVAIHEELSAQTAYLSAMYRHRPELTERLH 163
WP_011967257    83 VLIENVQNYIANYQIGDDCFIQNINVMLVEGKATFGNNVEVSVLNETGGREVPIYDGLSASLAYIIALYRHRPALIERLR 162 Parabacteroid...
WP_006744422    83 VYIDRVHNYIANYKIEDGTYIQNVNCIYVEGNSSFGNGTCVAVMNEQGGREVIIYDYLNAHFAYILTFYRHRPLLISKLQ 162 Bacteroides c...
Q5LHM9          84 CCIENIQNYIANYEIGNNTFIENVDIILVDGLTQFGNGVETAVLNETGGREVLINDKLSAHQAYILALYRHRPELISRMK 163 Bacteroides f...
CCZ87291        84 CYIENVKNYIANYEIGHDTFIENVDIILVDCHSRFGNGVEVSVLNETGGREVIIHDRLSAHQAYIMALYRHRPVLIDKMR 163
jgi:Poras_0974 162 TLVEKYTASVRSDRGTIGESSQIKHCGLMTNIKVGPHSSIIGASVLENGSVNSTVLSPTRIGYGVICRDFVFSAGCVVAD 241
WP_038554656   168 TMVDDYTQYVRSEMGVIGADSNILNCNTILNVKTGPATIIDGAKKLHNGSINSNYEAPVKIGEGVIMDNFIVSSGSKITD 247 Draconibacter...
Q7MTP4         167 AMARAYAESRRSDMGAIGSHVVIHGCNTIENVCIGDYTEITGASHLCNGSINSKKEAPVSVGYNVVCRDFILCSGSSVTD 246 Porphyromonas...
WP_013446291   163 HQISDYANSQKSDKGRIGKNVRIMNSDVIRNVRIDDFATIEGTLRLENGTISSNKQAPVYIGQGVQCKNFIICSGTNITE 242 Paludibacter ...
EHO42135       161 KMIDQYVEEQKSSIGVIGNQARVLRCNQIVNVKIGACAVIRGAQSLENGTIQSEKAAPVLIGDGVIARNFIVLSGSEVKD 240
CCY34444       164 AMADIRARAVASERGTIGPGARIENVGIIRNVRIGEAAVLQGCLRLFDGTVVSSTDAPVLIGSGVVCTDFIVQSGSVVEN 243
WP_011967257   163 DMITAYTEGIASTEGTVGDKVKIVNTGTIRNVKIGDYATIENSARLENGSVNSKREAPVFIGDSVIAQDFIVSSGAKIAD 242 Parabacteroid...
WP_006744422   163 DMVKKYSAYVSSTMGYIGKGVKIINTGSIKNVKVGDYTTIEGTQLLENGSINSNVHAPVHIGYGVVANNFIISSGVRMKD 242 Bacteroides c...
Q5LHM9         164 EITDYYSNKHASAVGTIGNHVMILNTGSIKNVRIGDFCRICGTCRLYNGSINSNESAPVHIGHGVICDDFIISSGSHVDD 243 Bacteroides f...
CCZ87291       164 KIIESYADAHASDTGTIGSHVMIVNAGYIKNVRIGDYCQIEGTGRLKNGSINSNEHAPVHIGYGVICDDFIISSGSHVED 243
jgi:Poras_0974 242 GSNVSRCFIGQGCSVTHLFSAHDSLFFANCQCENGEACAVFAGPFTVTMHKSSLLIAGYYSFLNAGSGSNQSNHLYKLGP 321
WP_038554656   248 ATLVSKCFIGQGCVLDKHYSAENSLFFANFQGFHGEACSIFAGPYTVTHHKSTLLIAGMYSFLNAGSGSNQSNHLYKLGP 327 Draconibacter...
Q7MTP4         247 GATVSHCFVGQGTHLGHLFSAHDSLFFANCQGENGEACAVFAGPYTVSMHKSSLLIAGLYSFLNAGSGSNQSNHLYKLGP 326 Porphyromonas...
WP_013446291   243 SALISNCFVGQACIIDKQFSAIDSVFFANCQGLHGEAVSIFAGPYTVTHHKSTLMLTALYSFMNAGSGTNFSNHMYKLGP 322 Paludibacter ...
EHO42135       241 GALLTDCFVGQGVRIGRQFSAENSAFFANCEGFHSEAVSVFAGPYSVTHHKSTLLIAGMFSFYNAGSGTNQSNHMYKLGP 320
CCY34444       244 GAVVTRSFVGQGVTLSKGFSCSDCLFFANSHCENGEAVSVFAGPFTVSHHKSTLLIGSMFSFMNAGSATNFSNHQYKLGP 323
WP_011967257   243 AAKIIRCFIGQACQVTHNFSAHDSLLFSNCAFENGEACAIFAGPFTVSMHKSSLLIAGMYSFLNAGSGSNQSNHMYKLGP 322 Parabacteroid...
WP_006744422   243 GVMLNRCFVGQACELGHTYTATDSLFFSNCQGENGEAASIFAGPFTVTHHKSTLLISGMFSFMNAGSGSNQSNHMYKLGA 322 Bacteroides c...
Q5LHM9         244 GAMLTRCFVGQACQLGHNYSASDSLFFSNCQGENGEACAIFAGPYTVTHHKSTLLIAGMFSFMNAGSGSNQSNHMYKLGP 323 Bacteroides f...
CCZ87291       244 GTMLTRCFVGQACHLGHTYSASDSLFFSNCQEENGEACAIFAGPFTVTHHKSTLLIAGMFSFMNAGSGSNQSNHMYKLGP 323
jgi:Poras_0974 322 IHQGVVERGSKTTSDSYVLWPSRIGAFSLIMGRHVDHIDSSDFPFSYIIENDNQTYLVPGTNLRSVGTIRDTKKWPKRDK 401
WP_038554656   328 IHQGIMERGAKTTSDSYMLWPTRIGAFTLVMGRHYKHCDTTDFPFSYLIESKDESILVPGINLKSIGTIRDTQKWPKRDK 407 Draconibacter...
Q7MTP4         327 IHQGIVERGSKTTSDSYILWPSRIGPFTLVMGRHVHHIDSSAFPFSYIIEDRNESYLVPGINLRSVGTIRDAKKWPARDK 406 Porphyromonas...
WP_013446291   323 VHQGITERGVKTSSGSYIMWPAKIGAFTVVLGRHKGNPDISELPFSYLLENEGESNLLPAINLHSAGTKRDVQKWQKRDI 402 Paludibacter ...
EHO42135       321 VHQGILERGAKTGSFSYLLWPARVAPFTAVIGKHYANFDAANLPFSYIEEVAGRTLLTPGMNLFTVGTRRDSAKWPKRDR 400
CCY34444       324 VHQGVFGRGVKCGSGSYMMLPVRVAPFTTVLGHHTGRIDTPDMPFSYILESEGRSYLVPGVNLRSVGLFRDIRKWPSRDR 403
WP_011967257   323 IHQGIVERGSKTTSDSYILWPARIGAFSLVMGRHHHHSDTSDIPFSYLIEKDDETYLVPGINLRSVGTIRDAQKWPKRDK 402 Parabacteroid...
WP_006744422   323 IHQGIIERGGKTTSNSYILWPARIGAFSLIMGRHTNNSDTSNLPFSYLIENNDQSILVPGVNLRSVGTIRDAKKFPKRDK 402 Bacteroides c...
Q5LHM9         324 IHQGTLERGAKTTSDSYILWPARVGAFSLVMGRHVNHADTSNLPFSYLIEQQNTTYLVPGVNLRSVGTIRDAQKWPKRDK 403 Bacteroides f...
CCZ87291       324 IHQGALERGAKTTSDSYILWPARIGAFSLVMGRHVTHPDTSNLPFSYLIEEKNTTYLVPGVNLRSVGTIRDAQKWPKRDQ 403
jgi:Poras_0974 402 RHPEEKLDCINFNLLSPYTVGKMYKGWHKLKALETHLGSSNATYIYHDMHIRHSSLVKGCRYYEMGIVKFLGNSLIQRIQ 481
WP_038554656   408 RTDSNLLDLINFNLLSPYTIDKMIKGREKLMELQKSSDENTEVYTYDRMKIEKHALNRGIQLYEMAIWKFLGNSLITRLN 487 Draconibacter...
Q7MTP4         407 RKDPDLLDNINFNLLSPFTAGKMMRGSRKLKKLRKILGSEGQTYVYHDMRIRSSALDKGLMFYEMGLNKFFGNSIIKRLE 486 Porphyromonas...
WP_013446291   403 RTDEIKLDPINFDFLSPYTLSKALKGINILNGLLENMEAGASFVWYQNCKIKRSSIKKGIELYEMAINQFIGDKIIEKLS 482 Paludibacter ...
EHO42135       401 RKGENKLDLIHFDLFSPFVINRVRKGKKILAELYAAANPKQEFVKFKGLYLKRLLLKRGIKYYQMAMDIFVGEQLLRRLQ 480
CCY34444       404 RSLSGRMDNISFEVFSPYTAGAMLSGRDRLVQMLSEERFSGTPSSYGGCTIAGSSLTSGVERYEKALKYYVGLQVALALR 483
WP_011967257   403 RTDPDRLDMINYNLLSPYTIQKMLKAVDILKNLQALVGETSEIYYYQNTRIKGSSLRNALNFYGMAINKFFGNSLIKRLE 482 Parabacteroid...
WP_006744422   403 RTDPHPLDFLNFNLLSPYTIQKMLKGIDVLENLKMTCGE-SKTYGYQGCVINGRSLHRGIELYHMAIRKFLGNSLISRLT 481 Bacteroides c...
Q5LHM9         404 RTDPNRLDYINYNLLSPYTIQKMFKGRSILKELKRVSGETSEIYSYQSAKIKNSSLNSGIRYYEIAIHKFLGNSIIKRLE 483 Bacteroides f...
CCZ87291       404 RKDPNRLDQINYNLLSPYTIQKMMAGRQILKELARVSGETSEIYSYQSAKIKNSALNKGIKFYETAIHKFLGNSVIKRLE 483
jgi:Poras_0974 482 TQ-APKSKRELVTCLSPTSNEGLSDWLDLAGMIAPRRLIRSLITQIKEGQIKTLQEVNVAIRSIHSRYYEIEWHWAYDLL 560
WP_038554656   488 GN-EYEIAADIQKALQPDMKFGKGYWVDLAGMICPFEALDQLLQAIENGSVQSLEEVNSALATIHKNYYNFEWTWAVDVL 566 Draconibacter...
Q7MTP4         487 DC-PCRTDEEVLSALKPTHNEGDGSWVDICGMIAPQQQIHRLASLIKEGKIKSLAEVNERMKEIHSRYYDYEWCWAYNAL 565 Porphyromonas...
WP_013446291   483 QL-EIFSKDNLHKLLSTKTDTGIGEWSDMAGLIAPKSEINRLLKDISDKKL-SLDEIQNRINELHANYAAYSFVWVKSIL 560 Paludibacter ...
EHO42135       481 PIdELKGWTDVAARLKAPNTKKLEEWYDWFGMFIPQSAAEELLGKIKSNQIKTVQDLLTQLRQYFERYDEWAWNWTAALL 560
CCY34444       484 GR-KLGSDEAITAALTPVSPVGDGRWIDVAGLLAPKAEIDQIVEEVVSGSLDTPGAVESRLSAIASNYQLYEWRWVYAHI 562
WP_011967257   483 GT-TYCSMEEVWEQLRPTESKGSGEWLDLAGLILPREPLEALLQDIEQGEIASLEDVECFFRLVHGRYYSLEWTWAYEMI 561 Parabacteroid...
WP_006744422   482 KC-SCESDEIIRECLKPDSSIGLGDWRDLAGLIAPQSEIVKLLNDVENDRITNSKQIYDQFEYLHENYYAIEWTWAWEKI 560 Bacteroides c...
Q5LHM9         484 GI-NFKDNEEIRRRLKPDTEIGVGEWVDIAGLIAPKSEVEKLIDGIESGEINRLKSMNACFAAMHDNYYTYEWTWAYHKI 562 Bacteroides f...
CCZ87291       484 AI-RFASDEEIRARLVPDTPIGTGEWVDISGLIAPKSEIERLMEDIECDRLSSVDEIHDRFAEMHANYYTYEWTWAYEKM 562
jgi:Poras_0974 561 LRWYDISAKDLTVERVIQIVKEWQETVIALDECLLKDAHKEFEMLTQVGFGIDLNGEHnRRIDFEQVRGSYEDNAFVAEV 640
WP_038554656   567 ESFYGKSISEFEASDVISIVKKWKESVLGIDRFLYEDARKEFSMSKMTGFGVDGQNGA-RELDFTEVRGEFENNDTVKEI 645 Draconibacter...
Q7MTP4         566 LEWYELNPEDLTRSKVAELVHTWMRSVIRLDEMLYEDAKKEFQMHSQVGFGIDLVGEM-KHRDFDEVRGDFESNPFIVEV 644 Porphyromonas...
WP_013446291   561 EKQVGKPIHE--KEVIISSIENWKKAVQTFEDMILRDAKKEFNSISKTGFGLDGDDSD-KQLDFENVRGNFEENAFVIET 637 Paludibacter ...
EHO42135       561 KEEWQIDVETIEKDQFKQLIANWKNQKIRFNNLILSDAQKEFDSNSRIAYGIDGDEQI-ALKDFEAVRGTLEENGFYKEL 639
CCY34444       563 RTVYNVDPQKITRKKLIELLRQWRAASESLFADIEMDASKEFGEGGMTGFGLDVTDRDeILADFRHVRGEFDSDSQVAAV 642
WP_011967257   562 ERYYGVDLRSISAAEIIDLVRRWQECVIRLDEMLYEDARKEFSLTSMIGFGVDGSNKE-KQQDFEGVRGDFVNNPFVTAV 640 Parabacteroid...
WP_006744422   561 KSYYGVNLNSITAQDVILIVEEWKKAVTGLDKMIYEDAKKEFSLSSRISFGLDGNRYV-QKVDFEKVRGLFEDNDFVKTV 639 Bacteroides c...
Q5LHM9         563 QEFYGLNPETITAKDIIAIVRAWREAVVGLDRMVYDDARKEFSLSSMTGFGADGSRDE-MKLDFGQVRGDFESNPFVTAV 641 Bacteroides f...
CCZ87291       563 LDFYGLQTDKITAADIAAIVRQWQEAVVGLDKMVYEDAKKEFSLTSMTGFGADGSSEE-KMRDFEEVRGVFESNPFVTAV 641
jgi:Poras_0974 641 HDHIRRKKLLGETILAQ 657
WP_038554656   646 KEHMKKKERLGSRVIEQ 662 Draconibacterium orientale
Q7MTP4         645 VEHIRKKRALGEEMLSR 661 Porphyromonas gingivalis
WP_013446291   638 TNRLKTDIELANKILAK 654 Paludibacter propionicigenes
EHO42135       640 LAENEQM----EKIAER 652
CCY34444       643 RETRERVAMLADEVLSa 659
WP_011967257   641 QEHIVNKRALGDELIER 657 Parabacteroides distasonis
WP_006744422   640 LKHIEDKTRLGDELIHR 656 Bacteroides coprosuis
Q5LHM9         642 LKHIDDKTALGEELINR 658 Bacteroides fragilis NCTC 9343
CCZ87291       642 LEHIKVKTELGNELIER 658
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