Conserved Protein Domain Family
ArdcN

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pfam08401: ArdcN 
N-terminal domain of anti-restriction factor ArdC
This is the ssDNA binding domain of anti-restriction factor ArdC deployed by plasmids and phages in polyvalent proteins related to the BHD domains of XPC/Rad4 and the Tc-38 domain found in kinetoplastid minicircle binding proteins. The structure of this domain is composed of three alpha-helices and a three-stranded beta-sheet that supports a long and protuberant beta-hairpin. This domain is also found in the N-terminal region of the RP4 TraC1 primase, together with the Toprim domain (pfam01751, pfam13362 and pfam13662).
Statistics
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PSSM-Id: 429975
Aligned: 108 rows
Threshold Bit Score: 42.3311
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_117701481    19 DRALDTF---------------ANMMIEKIESL-GSkdGWQKPWFTEGTLSWPKNL-SGREYNGMN-ALLLTMLCek--- 77  Bacteroidales
CDA66406         9 KNAAERQ---------------VSLITEALSKAaDNkgVWLNEQGKQ----YPRFYpKGAAVSPFN-ALVMGLNSdk--- 65 
CCG53567        94 DDIYSYI---------------TDLIINTIEKVgHL--PWQKDWVGSGSDGAAKNYvSKKEYTGANfLLNFDIKFdkdgk 156
jgi:Cyagr_1275  21 tgHEERL---------------THSLIELMANG-VN--PWRKPWNPNRGG-SHRNLvTGHHYTGGN-PVLLEMQMaa--- 77 
Q9RMV4          17 KEETKEI---------------MDKVLTDITK------YYNSPEDMLE---LANFMaQFSNYSPRN-MQLIKSQFph--- 68  Bacillus anth...
EYT56587        41 EANLEQM---------------ESQLTRRVDEL-VTgdQWLE---------AMRFAaQFRGRSFLN-TLLIQVQHlnays 94 
EGN33897        31 KQQREEV---------------WAEVDAQAQAVfQNgdSLKG---------FLDFMaQCNTQKTPN-LLLIYGQNpe--- 82 
wustl:cce_4767  15 SKAMELL---------------EEGISNLLQSG-----DWRQ---------YLQVQsQFHNYSFNN-IVLIVLQYpk--- 61 
WP_076004649   203 PEAKERR---------------IDEVLKKLKEG-VEgiQGSEHFRN-----FLLTMsKFHDYSIGN-LILIAAQKpd--- 257 Dehalogenimon...
Q4CVC0          64 RRVAKNMpmvvaqvpmstvlfnMDQLLPESEA------HWQLPIAT-----AATSVsSMRPYEGQA-QRQLEHRRmt--- 128 Trypanosoma c...
WP_117701481    78 -----kgYELPVFCTFNRAVGLNYQtdkqgnkkqmvdangeplpkvgINKGEKSFPVM--------LTS----------F 134 Bacteroidales
CDA66406        66 -----ngYATNLYTLFSEAKKRDES----------------------VMAHERGVPFN--------WYAw--------nK 102
CCG53567       157 gylvpikFIQPYYLTFNQIKETGAS----------------------LKKDSKARRVI--------YYTmifsfdngvlQ 206
jgi:Cyagr_1275  78 -----rgSELPLWLGYNQAKEQGWS----------------------PHKGSKACIII---------------------- 108
Q9RMV4          69 ---------ayACASFKTFKDAGFH----------------------VNKGEKAMKVFhpy--vkeFVR----------- 104 Bacillus anth...
EYT56587        95 egrvptpYP-SYVAGRSDWRKLGRW----------------------PAKEQTGYLVRkpvveryaATN----------- 140
EGN33897        83 ---------atVVKSYDYWKKEHRS----------------------PKSGVHGYTYM---------------------- 109
wustl:cce_4767  62 ---------asRVAGYRKWQELGRQ----------------------VKKGSKAIKILapltkk---------------- 94 
WP_076004649   258 ---------atRVGGFNTWKDLYRW----------------------VKKGEKGIAILap------------------cL 288 Dehalogenimon...
Q4CVC0         129 -----cgFESNWWGTRLQWRKRGCHldpkavpsvlhfhkmtrlvhisMLSGGKE-------------------------- 177 Trypanosoma c...
WP_117701481   135 TIVHKETKekipyddykrmsAEEQK-EYNVYPK-LNV------YQVF 173 Bacteroidales
CDA66406       103 YVNRHNPEdiisrkdyqelsATDQT-QYKGIHN-REI------RVLF 141
CCG53567       207 FKTTDREKftefvksngltkEDLRE-HLTKIPV-IKY------YNVF 245
jgi:Cyagr_1275 109 -------RpqfnqyeeldadGNPQR-DANGEPV-ITTwvsykpAAVF 146
Q9RMV4         105 -----DPKtklpipltkltaEQKQQvKNGELKV-EKQtnyylkATAF 145 Bacillus anthracis
EYT56587       141 --PASGRWrklgsrekprpgETVRE-KMVNVTY----------GKVW 174
EGN33897       110 --------------------VSTEYeKDGEMRTgYAI------GKGF 130
wustl:cce_4767  95 ---------------iekenDNGEK-QKINALVgFRT------VNVF 119
WP_076004649   289 PSKSAKMTepagaedkkkegEEEEK-REMIRPIyFKV------VYVF 328 Dehalogenimonas formicexedens
Q4CVC0         178 --------------------------LLKDSFVsGKTgiirqlSVSN 198 Trypanosoma cruzi
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