1YGE,1RP1,1OLP,1LOX,1BU8,1CA1


Conserved Protein Domain Family
PLAT
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cd00113: PLAT 
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PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates.
Links
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Statistics
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PSSM-Id: 238061
Aligned: 24 rows
Threshold Bit Score: 72.3716
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1YGE        6 HKIKGTVVLmpknelevnpdgsavdnlnaflgrSVSLQLISatkadahgkgKVGKDTFLegintslptlgagesAFNIHF 85   soybean
126308    352 YHYQLKIQFinqte--------------tpiqtTFTMSLLGt--------kEKMQKIPItlgkg-----iasnkTYSFLI 404  human
1OLP_D    256 NEIVVMIKTadvqd--------------agtdnYIYFGIETkd-------gVKEEWALDnpgnd-----ftrnqEGTYTL 309  Clostridium absonum
Q9NTG1   1230 LCYLVTIFTgsrwg--------------sgtraNVFVQLRGt--------vSTSDVHCLshphft---tlyrgsINTFLL 1284 human
AAH41860  647 VLYEMTVWTgdvvg--------------ggtdsNIFMTLYGi--------nGSTEEMQLdkkkar----fereqNDTFIM 700  human
T29532    722 GRWEFRLHTlnsdl--------------ggttsHLKIIGYGde-------nWLADDIPNdsllr------dpsqVPRIQV 774  nematode
1CA1      256 KELVAYISTsgekd--------------agtddYMYFGIKTkd-------gKTQEWEMDnpgnd-----fmtgsKDTYTF 309  Clostridium perfr...
AAC27073   34 CPYTVVVMTsclsp--------------estrdQISIVFGDa--------dGNKVYAPKlggsvrgpgglgkcsTNTFQV 91   thale cress
AAM63873   40 CPYTVIVTTscfsp--------------dwsrdQVTIALGDa--------dDNQVVAPRldkplsggggfekcsSDTFQV 97   thale cress
AAC23732   48 CSYTVIIKTscssv--------------sytrdKISISFGDv--------yGNEVYVKRlddpssr--tfekcsSDTYKI 103  thale cress

1YGE       86 ewd---gsmGIPGAFYIKNYMQv----------------------eFFLKSLTLEAIsnqgtIRFVCNSWVYntkl---- 136  soybean
126308    405 tld---vdiGELIMIKFKWENSavwanvwdtvqtiipwstgprhsgLVLKTIRVKAGetqqrMTFCSENTDDlllr---- 477  human
1OLP_D    310 klknkntkySDIKNMWIRDEKLtva------------------tdgWKPSYVKVIAGdk-vrLEKNINEWISgg------ 364  Clostridium absonum
Q9NTG1   1285 ttk---sdlGDIHSIRVWHNNEgrs-------------------psWYLSRIKVENLfsrhiWLFICQKWLSvdt----- 1337 human
AAH41860  701 eil----diAPFTKMRIRIDGLgsr-------------------peWFLERILLKNMntgdlTMFYYGDWLSqrkg---- 753  human
T29532    775 dfg----niGRLQKVRFEIQPAgdq-------------------pnYYLEYVEAQDLdtrerCVLMVNNWLLkeatpgyr 831  nematode
1CA1      310 klkdenlkiDDIQNMWIRKRKYtaf------------------pdaYKPENIKVIANgk-vvVDKDINEWISgn------ 364  Clostridium perfr...
AAC27073   92 rgq---clnDPICSLYINRNGPd----------------------gWVPESIEIYSEgs-ksVKFDFSKSVPqlntw--- 142  thale cress
AAM63873   98 kgk----clNTICSVYIYRSGTd----------------------gWIPETVEIYKEgs-ksVKFDFNKNVPeniw---- 146  thale cress
AAC23732  104 sgp----cmRDVCYLYLLRQGSd----------------------gWKPENVKIYGSsi-rsVTFYYNLFLPnsvw---- 152  thale cress

1YGE      137 -yksVRIFF 144  soybean
126308    478 -ptqEKIFV 485  human
1OLP_D    365 ---tTYTLK 370  Clostridium absonum
Q9NTG1   1338 --tlDRTFH 1344 human
AAH41860  754 kktlVCEMC 762  human
T29532    832 kfqsFREIA 840  nematode
1CA1      365 ---sTYNIK 370  Clostridium perfringens
AAC27073  143 yghnNCNTT 151  thale cress
AAM63873  147 -ygnNYCNN 154  thale cress
AAC23732  153 -ygfNVCNG 160  thale cress
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