Conserved Protein Domain Family
Ground-like

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pfam04155: Ground-like 
Ground-like domain
This family consists of the ground-like domain and is specific to C.elegans. It has been proposed that the ground-like domain containing proteins may bind and modulate the activity of Patched-like membrane molecules, reminiscent of the modulating activities of neuropeptides.
Statistics
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PSSM-Id: 461200
Aligned: 89 rows
Threshold Bit Score: 55.324
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003103504   26 GEKCNDVILYDIIKkvrflfETHsfsisfkasktTVDPTEIRQ---TAMKTMEEVFPLsrSMGCICTDHKFQFpN-FTNH 101 
Q9TYW7         33 QLFCCDSTIKTVVEtg---mQTLdlfg----aggPQTLGPIVQ---ALSTFVQQHFKT--AYEIVMAPKDFVLnThYNGT 100  Caenorhabditi...
O02154         35 DLYCCDSTIKTVIKrg---iRTLsyfg----ddgPQTLGPIVQ---GLSTYVQRHYGV--AYEIVLAPKGFILnSnYNGS 102  Caenorhabditi...
Q9XV14        278 GNKCCDARLAATMRda---mRQMatsp----efgPGKEGIVAA---ELQQSVQTRFKK--SYEIIVSRSDFVAtTyTAGE 345  Caenorhabditi...
EGT59436      288 GNKCCDGRLASTMRda---mRHMatsp----dfgNGKEGIIAAifqELQQKVQQRFKK--SFEVIVSRSDFVVsTyTAGD 358 
4_pfamImport    1 GNKCCDGRLASTMRda---mRQMatsp----sfgRGKEGIIVS---ELQQKVQERFKK--SYEVIVSQSDFAVsSwASGQ 68  
Q21835        288 GNRCCDGRLASTMRda---mRQMatsp----dfgQGKEGIIAA---ELQQKVQQRFQK--SYEIIVSQSDFVIsTyTAGD 355  Caenorhabditi...
Q9XV14         40 lVECCDKPLKQLIL------DTIhgt-----nfeSLANGDFAK---IVQRRAQMEFHS--SFETIVSKTNFAIsShYHGP 103  Caenorhabditi...
Q21835         56 tVECCDEELSKLIH------KTIldag----nnaKL--GNLAK---FIQRRSQLFYHM--SFETIVSRENFAIsThYHGT 118  Caenorhabditi...
EGT34445       35 klFCCDSTIKTVVEtg---mKTLdlfg----aggPQTLGPIVQ---ALSSFVQRHFKV--AYEIVMAPKDFVLnTnYNGT 102  Caenorhabditi...
XP_003103504  102 RYCSVKVSTFRCHAI 116 
Q9TYW7        101 SLCKFQSNSYTLAIY 115  Caenorhabditis elegans
O02154        103 SVCKFETNSYTMAVY 117  Caenorhabditis elegans
Q9XV14        346 KFCKFKTKNFVILAY 360  Caenorhabditis elegans
EGT59436      359 TFCKFENRDFYILAY 373 
4_pfamImport   69 SFCKFESKGFYILAY 83  
Q21835        356 NFCKFDNKGFYILAY 370  Caenorhabditis elegans
Q9XV14        104 HTCRVHKKGHYLLVY 118  Caenorhabditis elegans
Q21835        119 HSCRVHDNNLYYLVY 133  Caenorhabditis elegans
EGT34445      103 SLCKFQSNAYTLAVY 117  Caenorhabditis brenneri
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