1VHR,2J16,1MKP,2R0B


Conserved Protein Domain Family
DSPc

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smart00195: DSPc 
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Dual specificity phosphatase, catalytic domain
Statistics
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PSSM-Id: 214551
Aligned: 27 rows
Threshold Bit Score: 118.539
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VHR_A       29 CNEVTP-R-I-YVGNASVAQ--DIPKLQKLGITHVLNAAEGRSFmhvntnanfYKDSGITYLGIK-------AND----- 91  human
AAA66956     27 MMRVTD-Y-V-YLGNYNDA---KAAPTSGIGFKYILNLTTEKYT---------IKNSSITIIHMP-------LVD----- 79  Myxoma virus
NP_048659    25 PKKITN-H-V-WVGSEATAA--DPAFLKKNNIKLVVNCTADIPK---------Y--SNIPMLRVP-------VHDa---- 77  PBCV-1
AAA34477     63 PQEDHP-K-G-YLATKSSHL--NQPFKSVLNFFANNNVQLVVRLns-----hlYNKKHFEDIGIQ-------HLDl---- 121 baker's yeast
2J16_B       44 PLLVLPeK-I-YLYSEPTVK--EL-----LPFDVVINVAEEA---------------NDLRMQVP-------AVEyhhyr 92  baker's yeast
P43078      429 PKNVLN-N-LiYLYSDPAQG-----KIDINKFDLVINVAKEC-----------DNMSLQYMNQVPnqreyvyIPW----- 485 Candida albicans
NP_046165     4 ASQIDE-H-V-FVGGYYGDNeaMLRFIENHAIASVISLIDSDVA------------PIRHALGLP-------VGD----- 56  OpMNPV
NP_044033    28 ITRITE-Y-V-YLGSYNNAM---ALESSGVPFRYVLNMSMVrys---------lpGSSATIVHIPi------PDN----- 81  McVI
NP_495826     2 PFRSMK-DeL-IQKENVGGV---VCCTEEFELKAAMNAMREVDW---------KNe-gVEFFAVPm------KDF----- 55  nematode
ZP_07182338 307 VSKMTA-G-V-YLGAFPRHI---PAQNAVLDVTFEFPRGRa--------------TKDRLYFCVP-------MLD----- 354 Escherichia coli...
1VHR_A       92 -T---------QEFNLSAYFERAADFIDQAlA---QKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIV----- 153 human
AAA66956     80 -D---------EYTDLTKYFDYATTFLSNC-E---DKHYPVLVHCMAGVNRSGAIIMAYLMSRKSKDIPAFMYFLyiyhs 145 Myxoma virus
NP_048659    78 aF---------DADKMAKYLGVSSMAIRDV-T---RYKGNVLVHCRAGQNRSASVTAAYIMTIKGITAREAMDIV----- 139 PBCV-1
AAA34477    122 -I---------FEDGTCPDLSIVKNFVGAA-EtiiKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFL----- 185 baker's yeast
2J16_B       93 wE---------HDSQIALDLPSLTSIIHAA-T---TKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLL----- 154 baker's yeast
P43078      486 -S---------HNSNISKDLFQITNKIDKF-F---TNGRKILIHCQCGVSRSACVVVAFYMKKFQLGVNEAYELL----- 546 Candida albicans
NP_046165    57 -HihvyceaapTCAALPNAMPALYDYMVRR-I---GEGKRVLVHCYAGASRSAALAVYYLMRSRQMPYQDALNAV----- 126 OpMNPV
NP_044033    82 -----------DQVHIAKYFDGVAAFLERC-E---KSHTPVLVHCIAGVNRSGAMIMAYLLHTRNRQIPAVIYFLyvyhg 146 McVI
NP_495826    56 -----------TGTAPRAEINEAVEFIESV-A---SKGKTVYVHCKAGRTRSATVATCYLMKSRNWMSNVAWEFL----- 115 nematode
ZP_07182338 355 -----------LVVPEEGELRQAVAMLETL-R---EEQGSVLVHCALGLSRSALVVAAWLLCYGHCKTVNEAISYi---- 415 Escherichia coli...
1VHR_A      154 -R-------QNR--E-IGPNDGFLAQLCQLN 173 human
AAA66956    146 iR-------EQR--GaFLENPSFRRQIIEKY 167 Myxoma virus
NP_048659   140 -R-------SRKc-EtFRPS-NFTSSLKAYE 160 PBCV-1
AAA34477    186 -R-------FIR--PgMVVG-PQQHWLYLHQ 205 baker's yeast
2J16_B      155 -K-------SRA--DkINPSIGLIFQLMEWE 175 baker's yeast
P43078      547 -KngdqkyiDAC--DrICPNMNLIFELMEFG 574 Candida albicans
NP_046165   127 -Q-------SKRrvAiNDHFVRFLATRCSYR 149 OpMNPV
NP_044033   147 iK-------DIR--GaFLENASFKRQLVDHY 168 McVI
NP_495826   116 -K-------DKRh-QvLLRN-AHWRTVNEYR 136 nematode
ZP_07182338 416 -R-------ARR--PqIVLTDEHKAMLRLWE 436 Escherichia coli MS 196-1
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