Conserved Protein Domain Family
ET

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pfam01684: ET 
ET module
This domain has no known function. It is found in several C. elegans proteins. The domain contains 8-10 conserved cysteines that probably form 4-5 disulfide bridges. By inspection of the conservation of cysteines it looks like cysteines 1,2,3,4,9 and 10 are always present and that sometimes the pair 5 and 8 or the pair 6 and 7 are missing. This suggests that cysteines 5/8 and 6/7 make disulfide bridges.
Statistics
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PSSM-Id: 366757
Aligned: 55 rows
Threshold Bit Score: 38.4618
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003098573   444 CYSG-LYVDG----SPLsTSSdTKEVCQ-GRCTSIQYTSAIQGQIhiAKLYSCSPKTICEELDIKNGCYALTPG------ 511 
Q94247        1300 CYAG-ISSNYivngSAV-NVG-AQIPCN-GQCSSLS--GVVGGFQ--VNTYHCMPNSICNSLELYDNCKPVWNDn----- 1366 Caenorhabdit...
5_pfamImport     1 CYAG-LNSNYstngHPL-AVG-AQIQCS-GQCSSLS--AIVNGYK--VDTYHCVPNSICTSLELYNDCKRVHEDr----- 67  
16_pfamImport    1 CYVG-LQSTY----NSL-SLG-AESYCPaGQCASLN--GIVGGYN--VTTYHCVADSICKSLELKDRCTTLWNDr----- 64  
33_pfamImport    1 CFVG-IQSTY----DAL-SLG-SQIACD-GQCASFN--GVVGGYN--VTTYHCLSIQVCDSLKITNNCANLVGYg----- 63  
39_pfamImport    1 CYSG-FASDY----LGL-TVL-AQVPCD-GQCSSFS--GVISGDN--VTSYNCIPANECNYLGVSDSCLPVHEDr----- 63  
34_pfamImport    1 CYSG-LHSVSp--sNTI-SIG-AQIACD-GQCASFS--GFVNGNI--TTSYKCVPNSICDSFGLHNSCQHNGT------- 63  
17_pfamImport    1 CATG-LYNGS--------TWLgAEMNCQ-GRCGRLKFNA--NGQQ--VSYFSCMPYDVCAGFGL----ASTEDQtynppq 62  
36_pfamImport    1 CFSG-IYAQEk-------SNG-SEVLCD-GSCASIS--TTVNNDP--VTLFECVHPKYCQQLELDNSCETLFGD------ 60  
24_pfamImport    1 CLVGnLLVSE----NVItSKSvELKECE-GLCRKQTVTSPSGG----VVLLTCEENKLSTFINQEQECSSSGLE------ 65  
XP_003098573   512 ---VVECCCDS-DLCMDP 525 
Q94247        1367 --qVTGCCCNNaNNCNIA 1382 Caenorhabditis elegans
5_pfamImport    68 --qVHACCCNNvNNCNIA 83  
16_pfamImport   65 --sLTACCCNNaDNCNLK 80  
33_pfamImport   64 --kLIGCCCNSsDNCNVK 79  
39_pfamImport   64 --eITACCCNNaNTCVSP 79  
34_pfamImport   64 ---FTVCCCNNaNNCNIA 78  
17_pfamImport   63 ddeLEVFCCSGfNNCNVN 80  
36_pfamImport   61 ---KKTCCCDNyDNCNVD 75  
24_pfamImport   66 ----TSCFCKG-DECNKV 78  
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