Conserved Protein Domain Family
DDE_Tnp_1_4

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pfam13701: DDE_Tnp_1_4 
Transposase DDE domain group 1
Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.
Statistics
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PSSM-Id: 433414
Aligned: 31 rows
Threshold Bit Score: 377.324
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Cal7507_0622   15 FESVKSCPVVVNFNGETVTSDAGVTLIAELDRKREITSRLAGCFKDYREQNRIEHSVSSLIAQRVYGLVMGYEDINDHET 94 
jgi:Franean1_2409   3 QSTGVYPSVRIDAAGRGVVSAAGSVLLTETVRVSGLGRLLSDALAPWRSP-LATHDPAKVLTDLAVALALGGDCLADITL 81 
WP_024100385        3 KSTSSYPHVSASANGTGIVSHAGAVLLLRTAEKTGLTTALTTELARFRKP-LARHDPGKILLDLAVSLALGGDCLADINQ 81  Rhodococcu...
WP_015747335        3 KSTGLYPSLRVDATGKRVVSHGGSVLLALAADRVGLGRGLSAALRPWRKP-MAVHDPGKILLDLAISLAIGGDCLADIAQ 81  Nakamurell...
jgi:Bcoa_2151       7 KTLDFNHKIKLSNDGGSLSSDTGEFLFREFDEKIGFSKTLVKYLRLNDSRKYYLHSNENLLRQKVYQLIAGYAEDDAADQ 86 
Q9K5V1              7 LTLDFNRRIKLSTDGGSLSSDTGEFVFREFDEKIGFSDTLVQHLHLNDERKYYLHSNENLFRQKIYQLIAGYAEDDAADQ 86  Bacillus h...
BAK95424           10 LMFNSQKKISIANDGGTLTSDAGMVLVAEFLKKIHFDQLLNERIYINDGRKFSHHSWLEILKQWLYQLIAGYSRDRDANK 89 
WP_014124116       10 LTFNEQKAISIANDGGTLTNDAGLVLLSEFLNQIRFDSLLAQYVHIPEYRAFAQHEWLDVVKQWLYQLIAGYSRDRDANT 89  Tetragenoc...
WP_015076361        7 KHVKFNSKMVVSNTGGNLSSDAGLILVKEFMDSLGFYSFAKQFLHFNEDRIYWTHDNISLLEQLLFQLIAGYSADSSANL 86  Carnobacte...
bgi:05SSU0959       7 NQVKFNSNITISHTGGRLSSDSGLVLVKELMNTFGFSHLAKQWLHITDHRAYFTHDNLAILEQLIMQLIAGYSADSSANL 86 
jgi:Cal7507_0622   95 LRHDVMFALSVGksitsgqePVKMAGKSTLNRLEHCPEDVSNRAesryhriehdAEAIEKLLVEIFLESF-QKPPRQIVL 173
jgi:Franean1_2409  82 LRAEPAL-------------FGLVASDPTVSRTIDRLAGDAEKVltaldraraaARGQVWAAAGEHAPDHtVSVHDPLIV 148
WP_024100385       82 LRAQPEL-------------FGTVASDPTVSRLITTLAGDADIAlaaigrartaARAHAWTAAGSSAPDHtIDERTPLVV 148 Rhodococcu...
WP_015747335       82 LRAEPAV-------------FGHVASDPTVSRLIDTLAPDATAAlkaidtaraaARARAWKLAGPAAPNHdRSAKAPLVV 148 Nakamurell...
jgi:Bcoa_2151      87 LTHDPVFKEIIE--------TPTLASQPSLSRFYTRFDKDSIEQ----------LNLANQEVLDKIHC---FRQSKELFI 145
Q9K5V1             87 LTNDPVFTQVIG--------TNALASQPSLSRFYTRFDHESIEQ----------LHHANQELLDKVHE---LRESKALII 145 Bacillus h...
BAK95424           90 VQYDRLFQEALQ--------QENLSSQSMLSTFLHTLTTENVSQ----------LSQVAKDLADLWLD---HDNTQHLVL 148
WP_014124116       90 LQYDRLFKEALK--------QERLSSQFMMSTLLHTLTEENVNQ----------LLQVAKKLGDLGMD---QQNSQQLVL 148 Tetragenoc...
WP_015076361       87 LKEDPIFRLVLD--------KEAIASQASLSRFWDRISEENIAQ----------FQELNQAMLDKVRM---ERNNTQMII 145 Carnobacte...
bgi:05SSU0959      87 LRRDPVFQAVLG--------KKQLASQSSISRFLDRFTEENIDQ----------LQALNQSLIDKARL---IRNDTELII 145
jgi:Cal7507_0622  174 DLDVTDDLVHGNQEKSFFNPYYKGYCYAPLYIF------CGKHLLASKLRASNVDPAEEA-----LP-ELQRVIKLIRER 241
jgi:Franean1_2409 149 DLDATLVTAHSEKQDAAPT-FKRGFGFHPLWAFidhgqaGTGEPATVLLRPGNAGSNTAAdhitvATgALAQLP---ARL 224
WP_024100385      149 DIDATLVTAHSNKEHAAPN-FKRGYGFHPLCAFvdhgehGTGEPVAMLLRPGNAGSNTAAdhitvVQdALAQLPFD-PGY 226 Rhodococcu...
WP_015747335      149 DVDATLVTAHSEKQLAAAT-FKKGFGFHPIGAWadhgpdGTGEPLAMLLRPGNAGSNTAAdhisvVKaALAQLPCTTADR 227 Nakamurell...
jgi:Bcoa_2151     146 DLDSTHSDTYGDQESSSYNTHYGTMGFHPLVAFd----gATGDFLKAQLRPGNVYTSNGV-----VE-FIRPLIKHYNEM 215
Q9K5V1            146 DLDSTHADTYGQQEFTAYNTHYGTVGFHPLVAFd----gITGDFLKAQLRPGNVYTSNGV-----VD-FVEPLIKHYNEK 215 Bacillus h...
BAK95424          149 DFDSTACPTYGEQEEAEFIYHYGINGYHPFVTFe----gLTGLALDVRHRHGKSYTSTHA-----ED-YLEEMLDRYQQR 218
WP_014124116      149 DLDSTCCPTYGKQEAGEYIYHYGLNGYHPFVAFe----gLTGLALDVRHRHGKSYTSTHA-----ED-YLVEMLAHYQQR 218 Tetragenoc...
WP_015076361      146 DLDSTHSDTFGNQEKTEYNAHYGTQGYHPLVAFd----gLTGDFLKAELRSGNVYTSKGV-----KD-FLAPMLAHYCQV 215 Carnobacte...
bgi:05SSU0959     146 DVDSTHSDTFGRQEQTDYNAHYQTYGYHPLVAFd----gLTGDFLKAELRSGNQYTSKGV-----KA-FINPLLHHYKST 215
jgi:Cal7507_0622  242 WSNVKILVRGDSAYSREDIMSWCESQiGVDYVFGLAQNSRLIQLSQSTKYRAFLEYSQKIetvveffetlftpsddlkkq 321
jgi:Franean1_2409 225 RRSRKVLIRADSAGGTHAFLAWAHQR-RLAYSVGFTLPDNATQLIARLPKKAWTPAYDA--------------------- 282
WP_024100385      227 RVGKKVLVRIDGAGGTHSLIEYLTKR-RLSYSVGFGLTDAHAAAIDLVPDQAWTPAYDS--------------------- 284 Rhodococcu...
WP_015747335      228 RPGRGVLVRTDGAGGTHEFVDWMARQ-RVQYSVGFTLTTDITAKVDALPEAAWTPAYNA--------------------- 285 Nakamurell...
jgi:Bcoa_2151     216 FPETTLFLRGDSGFAVPGLYDLCEEE-SVLYIIRLKSNSQLQSLAKEYHPSSAPLDVSKT-------------------- 274
Q9K5V1            216 FPATTPFLRGDSGFAVPALYDLCERE-SVYYVIRLKSNAILQRMADECHPATVPSDVTKS-------------------- 274 Bacillus h...
BAK95424          219 SSDPLIMVRGDSGFAKPEIFSHCEDR-QVRYVIKLKSNARLLDHIQHQVLYQDDTDYTKT-------------------- 277
WP_014124116      219 SSDPTMLVRGDSGFAKPEIYKQCECR-GAHYVIKLKNNVRLIHYAQHLVQYTNGTDYTKT-------------------- 277 Tetragenoc...
WP_015076361      216 LPCTDILVRGDSGFATPEVYDTCESN-GSFYVIRLKSNKVVEKLAESYVLVGDNHSWDER-------------------- 274 Carnobacte...
bgi:05SSU0959     216 LPHTEILVRGDSGFATPEVYESCEAT-ESQYVIRLKSNRRLSQLAEHSVLYGDNQEWEER-------------------- 274
jgi:Cal7507_0622  322 atalvdsSVWYCSLDYKTFlS-------WSRNRRVVSKIEYSNEGVNT---RFV------VTSLPs----kKVPPGRLYt 381
jgi:Franean1_2409 283 -------DRQPRTGAFVAElSglmdltgWPPGMRVLVRKERPHPGAQL---RITdvdgnrITAFAtnsvrgQLADLELR- 351
WP_024100385      285 -------DGQVRDGAWVTEiTglldlstWPNGMRVIVRKERPHPGAQL---RFTdrdglrLTAFVtntrrgQLPDLELR- 353 Rhodococcu...
WP_015747335      286 -------DQEPRDGAWVAElTgvlklkgWPKDMRVIVRAERPHPGAQL---KFTdsngnrLTAFAtntkggQLADLELR- 354 Nakamurell...
jgi:Bcoa_2151     275 -------ETYYEETIYQAK-S-------WSKPRRVIIQSVRPAGELFFt-hSFF------VTNFE------LAFPQDIV- 325
Q9K5V1            275 -------ECYYEEIDYQAK-S-------WSKPRKVIIQSVRPAGELLFt-hSFF------VTSLGd-----IFSPKDIV- 326 Bacillus h...
BAK95424          278 -------EQQYFLMDYRAN-K-------WRQSRRVAMKATRLAGSLLFsdfQFI------VTNFE------NLDPKTIF- 329
WP_014124116      278 -------EHQYFKMAYQAD-S-------WDRSRTVAIKATRKAETLLFsefQFV------VSDFA------HLSPQTIF- 329 Tetragenoc...
WP_015076361      275 -------EVHHYSAFYQAN-S-------WPQKRRICIKSTREANQLVFs-hEYV------VTNFHe-----ELSAKTIF- 326 Carnobacte...
bgi:05SSU0959     275 -------EVQYFSLPYQAQ-S-------WSKPRRVCIRSVREGGELLFh-hAFI------VTNLSd-----NVSPEVIF- 326
jgi:Cal7507_0622  382 QKYCPRGNIENCFKEQKLELKSDRTSTHTFAGNQLRLWFTSIAYILMNALREKCLAKTELQNAQVGTIRTKLLKLGAIIT 461
jgi:Franean1_2409 352 --HRRRARCEDRIRAAK-DTGLTNLPLHDLDQNRVWCQIVALACDLIAWTQMLALADQPARRWEPKRLRHSLFWLAGRLA 428
WP_024100385      354 --HRRRARCEDRIRTAK-ATGLQNFPLHGFDQNRIWLALVQLACELLAWMQMLALTDTTARRWEPKRLRLRVLSIAGKIA 430 Rhodococcu...
WP_015747335      355 --HRRRARCEDRIRNAK-DTGLNNLPLNDFAQNQVWIAVVQLATELTAWMQMLAFTGTPARTWEPKKLRHRLFSVAARIG 431 Nakamurell...
jgi:Bcoa_2151     326 RAYQKRGTMENYIKEAKNGFYFDHMNSHAFLVNEVKMMLTLLAYNLTNWLRTLCFP-EGQKTMQIDTIRTRLIKAASKVV 404
Q9K5V1            327 RTYQKRGTMENYIKEAKNGFYLDKMSSHSFQVNEVKMMVSLLAYNLTNWLRTLCSP-EAQKGMQIETIRTRVIKVASKLV 405 Bacillus h...
BAK95424          330 QLYQKRGNMENFIKEMKGGFFAEKTDSASFTANQARLALSFMAYNIIHLMKHLTFP-STEKATVIDTIRFKLFHIAGRMT 408
WP_014124116      330 QLYQKRGNMENFIKEMKTGFFADKTDSPSFLANKARLALSFIAYNIIHLMKQLTFP-QEKKTTVIDTIRFQLFHIAGKVT 408 Tetragenoc...
WP_015076361      327 QIYHKRGTMENFIKEAKNGFYFDKTDSSSFLENHARMMVSLLAYNLVNFMKTICLP-EKEATFQVDTLRLRLFKVSGKLV 405 Carnobacte...
bgi:05SSU0959     327 SLYGKRGTMENFIKEAKGGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKSIGFD-KVNQGMTIHSIRLILLKVAGKLV 405
jgi:Cal7507_0622  462 VSRRRVLIAISNAYPYKEIFATAYNYLSRLKC 493
jgi:Franean1_2409 429 HHARQSVLHLAAHHPWTPLAIQAITTLRALPA 460
WP_024100385      431 RHARRVRLRLAATAPGVDVLVAGLNRLAALPA 462 Rhodococcus pyridinivorans
WP_015747335      432 RKARRTWLRLSAHAPHRDLLLHGLARLRNLPQ 463 Nakamurella multipartita
jgi:Bcoa_2151     405 KSGRSLYFKLSSSFVYQNFFWDVLNRIQKLQL 436
Q9K5V1            406 KSGRSLYFKLSSSFVYQDFFWKVLQRIQQLKL 437 Bacillus halodurans
BAK95424          409 AHARQIQIHLSNTNVYDTLFWDVLARIQRLNL 440
WP_014124116      409 EHARQVQIHLSSTNVYNTLFWEVLTRIQRLNL 440 Tetragenococcus halophilus
WP_015076361      406 HSGRRLLLRMSSYHVYQDLFYQLLDKIQQLSW 437 Carnobacterium maltaromaticum
bgi:05SSU0959     406 QTGRQVYLKLSSYHVYQTEFYKVFERLRRSKQ 437
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