Conserved Protein Domain Family
YPEH2ZP
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pfam14976: YPEH2ZP 
Yippee homolog 2 zinc finger protein
This entry represents a family of proteins (previously known as FAM72) that is distantly related to and named after the drosophila Yippee, a zinc-binding protein. In contrast to the other Yippee-like proteins, this family of proteins possesses some distinct features such as the presence of a second putative zinc binding site that is unique to them. The constituent zinc coordinating residues of this second site are invariant within the family suggesting that this is likely a genuine zinc binding site. This family of proteins is found in eukaryotes.
Links
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Statistics
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PSSM-Id: 405641
Aligned: 7 rows
Threshold Bit Score: 232.349
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001630310   6 HPLFQTKSVVRLECKFCERSICMRGMKAQLLADTNVELYSTDLPPENAIELVGPNYSTTNCDCKIKDIACLGCGNIVGYH 85 
1_pfamImport   1 NCTFKDRCVSILCCKFCKQVLSSRGMKAVLLADTDIDLYSTDIPPTNTVDFIGRCYFTGICKCKLKDIACLKCGNIVGYH 80 
XP_010722492   5 GCVFADRSVTVLCCRFCQQVLSSRGMKAVLLADTDTDLYSTDIPPSGTIDFIGSCYFTEICKCKLKNIACLKCGNIVGYH 84 
XP_004992804 138 QRMFADKVVFDLQCSYCETVVCRRAMKALLLADTSTELFSTDAAPEERCSPVGRLYSTPSCACQITDVACRCCGNVLGYH 217
XP_006000446   3 tSTFKNKCVSVLCCNFCDHILCTRGMKAVLLADAEIELYSTDIPPTSSVDFVGSCYSTEGCKCKLKDIACLTCGNIVGYH 82 
XP_006628526   3 TSTFKNRCVTLVCCKFCDSLLCTRGMKAVLLSDTKVELFSTDIPPHSTVDFVASCYCTESCKCRLKDIACLKCGNVVGYH 82 
NP_001013563   3 TSNFKNKCVTQINCIYCDSLLCTRGMKAVLLADTEIELFSTDIPPNRTVDFVASCYSTESCKCKLRDIACLKCGNVVGYH 82 

XP_001630310  86 VTVPCRSCVQSCNNGHFWMFHSSAAYAVERIDKKG-DMLVWGGLsPNcTEDQESDNDLEFEFEECCR 151
1_pfamImport  81 VIVPCSSCLLSCNNGHFWMFHSQAVYGINRLDSTGvNFLLWGNL-PE-TEECTDEEMLEISAEEYIR 145
XP_010722492  85 VISPCKPCLLSCNNGHFWMFYSQAVFGINRLDSSGvNVLLWGNL-PD-LEENTDEDMSCISEEEYIR 149
XP_004992804 218 VVEPCQSCLKACNNGHLWMFHGHTVRASHRVSPVTdQPLTWGIL-PSpGEDANGLCAHSPHSKR-VQ 282
XP_006000446  83 VVAPCKPCLLSCNNGHFWMFHSKAVSAFNRLDSSGmNLLLWGNL-PE-TEESENEDLDSLSEEECIR 147
XP_006628526  83 VVAPCKPCLLSCNNGHFWMFHSDSVSAVNRLDPSGlNLLLWGDL-PE-TESSEDEGTGDLSEEEYIR 147
NP_001013563  83 VVAPCKPCLLSCNNGHFWMFNSEAVSTINRLDATGqNLLLWGDL-PE-LEDSDDESLESFSEEEYLR 147
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