2B81


Conserved Protein Domain Family
lucif_BA3436

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TIGR03571: lucif_BA3436 
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luciferase-type oxidoreductase, BA3436 family
This family is a distinct subgroup among members of the luciferase monooxygenase domain family. The larger family contains both FMN-binding enzymes (luciferase, alkane monooxygenase) and F420-binding enzymes (methylenetetrahydromethanopterin reductase, secondary alcohol dehydrogenase, glucose-6-phosphate dehydrogenase). Although some members of the domain family bind coenzyme F420 rather than FMN, members of this family are from species that lack the genes for F420 biosynthesis. A crystal structure, but not function, is known (but unpublished) for the member from Bacillus cereus, PDB|2B81. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 274657
Aligned: 22 rows
Threshold Bit Score: 380.072
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2B81_A        21 A-KDQLTLGVHIPI-E-NYQFH-APTXEKQVELVQKAEQYGFTGVWLRDVLLQDPD---FGDPatGQ--IY--DXXIYLT 89  Bacillus cereus
WP_010953421  20 R-QGHLSLGLFFPL-E-AFEGD-TPSMLDQVALAKRAEALGFSALWFRDVPLRDPS---FGDV--GQ--VF--DPWVYLG 86  Pseudomonas
WP_011295693  20 S-SGSLSLGLFFPI-E-AFDGD-RPTMHNQVALAKRAEELGFSALWFRDVPLRDPS---FGDV--GQ--VF--DPWVYMG 86  Cupriavidus pin...
WP_011302265  15 Q-QGHLTLGLMLPF-D-NSE-NiALSFENQVDLAQYAENLGFTSLFVRDNPLYSPH---LGNV--TT--NY--DPFVFLS 81  Staphylococcus ...
WP_011148358  15 K-ENKISIGMFLPL----RALNqEADIKPEIDLIREIEQQNFSAIWLRDIPLFDPN---FGDI--GQ--GF--DPFVYAA 80  Photorhabdus lu...
WP_006768999  26 P-SNRMTLGLALPL-DsGDPERpDVDIPRQIGLIQRVEAAGFAAVWLRDIPLRDPD---FGDV--GQ--AW--DPVSYLG 94  Corynebacterium...
WP_003112461  24 A-ADALTLGLFLPL-R-FYQGD-MRVLLGQARLVEEIDRLGFAAVWVRDVPLFDPR---FGDA--GQ--VF--DPFTYLG 90  Pseudomonas
WP_011355782  17 S-DGRLSIGLTLPL---LRTGHiVADFDEQLELAALADTLGFRALWIRDVPLNSAD---YPDP--VG--HL--DPWVLLG 83  Burkholderia lata
WP_011014963  12 A-P-QITLGLMTPNgP-ELGRSeMVPTENSIELAIQAEAQGFRGMWVRDVPLAVPQgitVTDK--QA--TYldDPFLMLG 84  Corynebacterium...
WP_006768122  24 GgDAAISLGLMLPIgP-ELGREeMVPIQHSIDLTRRAEEAGFQGLWVRDVPLAIPQg--LSPE--NQqaVFldDPFLLLG 98  Corynebacterium...
2B81_A        90 YLASKTEKIAFGTSATVLSLRHPLRVAKEIATLDQLFPERIXLGVSSGDRRADFKALGVSHETRGEKFREAFAYLEEILY 169 Bacillus cereus
WP_010953421  87 YMAAHTTKIALGTASIALTLRNPLHTAKAAASIDQLSGGRLLLGVASGDRPVEFPAFSIDPEKRGETFQENFNVIRQAHR 166 Pseudomonas
WP_011295693  87 FMAAHTSNIALGTASIALPLRNPLHTAKAAASVDQLSNGRLLLGVASGDRPVEFPAFNIDPEKRGEIFRERVEVIRRVQH 166 Cupriavidus pin...
WP_011302265  82 YLSAKTSKIALGTSSIVATLRHPIHTAKAATSLDLISDERFLLGLATGDRPFEFPAFKIKETQLSKQFQDAIYAMNDLWQ 161 Staphylococcus ...
WP_011148358  81 WLAALTSKIAIGFGSAIFTLRHPIDLAKKATSIDQLSNGRLILGVAAGDRMSEFPAYNIPYNEKGMRFVESINMFRALLD 160 Photorhabdus lu...
WP_006768999  95 YLAASTSSLAMGTAAVVAPLRHPLHLAKQAASIDHLTGGRFLFGVATGDRTSEYPAFGADSGARDEVFREHLDVMQRAWT 174 Corynebacterium...
WP_003112461  91 YLAARTRRIALATGSAVLALRQPVDLAKAAASVDRLSGGRLVLGLASGDRPVEFPAYGLEHAQRGERFAQGLDYLRQLLH 170 Pseudomonas
WP_011355782  84 ALASRTRRIALASGAIVLPLRHPLHIAKGALSVATLSGGRFILGLGSGDRPPEYAAFGVDAETRRDRYRAHWDVVAAALG 163 Burkholderia lata
WP_011014963  85 AMASVTSTIALGTAATVLPLRHPLHVAKSALTLDRLSHGRFVLGIGSGDRPEEFEIFGKSLDNRRADIQSGWAILRAAL- 163 Corynebacterium...
WP_006768122  99 AMAQATSTIALGTAATVLPLRHPLHVAKSALTLDRLSGGRFILGIGSGDRPEEFEIFGRDLDGRREAIRRGWTLLRAAFS 178 Corynebacterium...
2B81_A       170 KNFPSIQStlGEV--HG-ANLVP-KP-SKRVPTFITGFSQQNXEWFAEHGDGWXYYP------RSPVHQAGAIGQWRELV 238 Bacillus cereus
WP_010953421 167 THFEPIRWshGEL--LG-ADLVP-KPtTREIPLFVTGHSRQPLDWIARESHGWINYP------RPPKIQRLIVEDWRQEI 236 Pseudomonas
WP_011295693 167 TSFEHVSWsdGEL--IG-ADLVP-KPtTKEIPLFVTGHSRQSLDWIAKHGCGWITYP------RPPHLQRLFVDKWRQEV 236 Cupriavidus pin...
WP_011302265 162 SHSPKISNsiFELyeDSgLQILP-K--HNHIPMFATGYSRQELSWIKKNMDGLMFYP------QPFQKQKALLKEWHNN- 231 Staphylococcus ...
WP_011148358 161 NNNRTINSplGYI--DGnLRLIP-KAvNDFIPLIVTGRGQQDIKWIAENSDGWFTYPiqthnkEGVAKLGKNISEFRQNI 237 Photorhabdus lu...
WP_006768999 175 TEKRGIRWsgGRM--WGg-DVIP-KPmAVRPPLLTVGSCLQSMAWHREHADAHVTYQ------RPLETQRTYIAGWREd- 243 Corynebacterium...
WP_003112461 171 -GCRHVASplGTL--Dd-AELLP-RPpAGAIPLVVTGSARQPADWLARQADGWLTYPestvdaSGPRRLARKIRAWRMSI 245 Pseudomonas
WP_011355782 164 VPSRVLPDeaPPD--APeFTLLP-RG-NDAVPMLAVGSGGQSVDWIARHSIGWMTYH------RDPDTQRVRYSMWRAAV 233 Burkholderia lata
WP_011014963 164 -------SpdPAM--RAdLEFAPtTPpEAQIPMIAVGSARQTVQWIARNADGWATYY------RPAEAQVGRLDLWDKAR 228 Corynebacterium...
WP_006768122 179 -PDEAGRAplYEV--TGgHAPTT-AP-EAQIPLIAVGSARQTVQWIVRNADGWATYY------RPAEQQVGRLDLWNQAR 247 Corynebacterium...
2B81_A       239 ---Edy-hpDVFKP-FIQPXHLDLSEDPNERPTPIRLGY--RTGRKALIELLDIYKSIGVNHLFLALFDGQRPADEVLDE 311 Bacillus cereus
WP_010953421 237 ---Vkq-cdTIYKP-FLQSLYINLDEHPSTPPSHIHLGF--RLGRNHLRTLLDTLQEIGVDHVILNLKYGKRPAAEVIEE 309 Pseudomonas
WP_011295693 237 ---Ivq-sgSEYKP-FMQSLYIDLDASPSTAPSPIHLGF--KLGRRHLIDLLDALQEIGVDHIILNLKYGHRGAAEVVEE 309 Cupriavidus pin...
WP_011302265 232 ---------DVFKP-FMHPLVIDLSLNPNELVKPIKGGY--RLGRNTLLNILKSYEKIGTNHMMLHLTSNDRPYKSLLTE 299 Staphylococcus ...
WP_011148358 238 ---Pg----NMFKP-HLTNEWIDLVEDKYYPRTPTNGGFilKTGRLGLIELLEEWQEVGVNHAALGIQYGKRPPKEVIQE 309 Photorhabdus lu...
WP_006768999 244 ---------GNTKP-FAMSMSLDLHADAHAPAGAIKFGW--RVGARRLVEILQELEAMGVDHVILGLKRGTRPVEEVLDD 311 Corynebacterium...
WP_003112461 246 ---Ad----GGFRP-HMTNEWLDLVDDPAYPRTPLHGGYvlRTGRNGLIELLGEWRAAGVNHAALGIQFAARPAAEVIQE 317 Pseudomonas
WP_011355782 234 drlAs----PAFRA-FGVSMRLDLLADPEAPATALPLGY--AAGRRALIDILRDMRAAGTHHVTLNPG-SDRPVREVIEE 305 Burkholderia lata
WP_011014963 229 ---------GGTRPlLISSMGLNLTEGNTH--KEITLGV--EVGSQELIEHLHRLSELGIDHVIFNIQ--RRPASEVLTQ 293 Corynebacterium...
WP_006768122 248 ---AsvrnpTNPDPlLISSMGLELTDTSGE----IELGL--RTTSQGLIDHLHTMRELGIHHVILNI--SGRPAGEVIDQ 316 Corynebacterium...
2B81_A       312 LGEEVLPHF 320 Bacillus cereus
WP_010953421 310 IGKHIVPQF 318 Pseudomonas
WP_011295693 310 LGTHVVPRF 318 Cupriavidus pinatubonensis
WP_011302265 300 VGDYIIPHF 308 Staphylococcus saprophyticus
WP_011148358 310 IGEEVLPAF 318 Photorhabdus luminescens
WP_006768999 312 LIAEVLPGF 320 Corynebacterium efficiens
WP_003112461 318 LAEEVLPLF 326 Pseudomonas
WP_011355782 306 IAEHVLPAF 314 Burkholderia lata
WP_011014963 294 IYEEVLPHL 302 Corynebacterium glutamicum
WP_006768122 317 IGAEVLPHL 325 Corynebacterium efficiens
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