Conserved Protein Domain Family
poly_gGlu_PgsB

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TIGR04012: poly_gGlu_PgsB 
poly-gamma-glutamate synthase PgsB/CapB
Of four genes commonly found to be involved in biosynthesis and export of poly-gamma-glutamate, pgsB(capB) and pgsC(capC) are found to be involved in the synthesis per se. Members of this family are designated PgsB, a nomeclature that covers both cases in which the poly-gamma-glutamate is secreted and those in which it is retained to form capsular material.PgsB has been shown to have poly-gamma-glutamate activity by itself but is bound tightly by PgsC (TIGR04011). [Cell envelope, Other]
Statistics
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PSSM-Id: 188527
Aligned: 11 rows
Threshold Bit Score: 516.491
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011118210  19 MVEAYWYRRQLLKIPFRIHVNGTRGKSSVTRLIAAGLRSGGIRTCAKTTGTLARMIL-PDGQELPIFR-PDRANVIEQKR 96  Rhodopirellula ...
AAA22286      17 IWEQRCHQKRLNSIPIRVNINGIRGKSTVTRLITGVVQEAKYKTVGKTTGTSARMIYwFTDEEQPIKRrKEGPNIGEQRR 96  Bacillus anthracis
WP_011201748  32 IYEKRRHQQNIDALPVRVNINGIRGKSTVTRLTTGILIEAGYKTVGKTTGTDARMIYwDTPEEKPIKRkPQGPNIGEQKE 111 Bacillus lichen...
WP_011302326  16 IVEKRQHSDRLEKIPIRININGIRGKSTITRLIYSILREDQYRVIGKTTGTDARMMYwFTPREYPVYRkPQGANIGEQRD 95  Staphylococcus ...
WP_011274856  16 IKEKNRHTNRLNKIPIRININGIRGKSTITRMIYSVLREDHYHVIGKTTGTDARMLYwFTDKEYPVIRkPQGANIGEQRD 95  Staphylococcus ...
WP_011064602  20 VKDKMINDKNVASIPVRINVNGIRGKSTVTRLITGVLQEAGYHTVGKTTGTDARMLYwFDSQEAPIQRrLEGPNIGEQRK 99  Oceanobacillus ...
WP_003020724  21 IIENIVHNNSIKSIPIRIHVNGTRGKSSVARLIAAGVRAGGYRTVAKTTGTLARYID-VDGSETPVFR-IGFSNIAEQVK 98  Francisella tul...
WP_011235626  22 AFEAVRHWALVRKIPVRVHVNGTRGKTSVTRLIAAGLRSGGKRICAKTTGSAAAITD-PDGREFPIYR-ISGANIIEQMR 99  Idiomarina loih...
WP_011461797  16 VYEQIRHNRNLNSIPLRVNINGTRGKSTATRLITGILKEAGEKVVGKTTGTSARIIYwDREEEEPIKRgPLGPNIIEQKT 95  Desulfitobacter...
WP_005903746  17 FFEKINLDKNRKNLKYIIHINGIRGKSTVSRLIDAGLRAGGYKVFTKTTGTSPRIID-TNAKEFEINR-QGKANIREQIS 94  Fusobacterium n...
WP_000007606  18 FLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWKVFAKTTGSTASLLF-PNRSESFIFR--NKISIEEQKS 94  Leptospira inte...
WP_011118210  97 IVQTAVGHNADALVIECMALQPLLQSVCELKLVRSTHGVITNARADHLDVMGPTRLDVARALSATTPISGDMFTAEDraD 176 Rhodopirellula ...
AAA22286      97 VVKEAADLEAEALICECMAVQPDYQIIFQNKMIQANVGVIVNVLEDHMDVMGPTLDEVAEAFTATIPYNGHLVTIES--E 174 Bacillus anthracis
WP_011201748 112 VMKETVERGANAIVSECMAVNPDYQIIFQEELLQANIGVIVNVLEDHMDVMGPTLDEIAEAFTATIPYNGHLVITDS--E 189 Bacillus lichen...
WP_011302326  96 IIKKVVKQKANALVNECMAVNPDYQITFQKELVKANIGVIVNVMEDHMDVLGPTLDEVAEAFTATIPYKGHLIVMKD--D 173 Staphylococcus ...
WP_011274856  96 IVRKVVKQKADSLVNECMAVNPDYQITFQKDLVKANIGVIVNVMEDHMDVLGPTLQDVAQAFTATIPYKGTLVVMKD--D 173 Staphylococcus ...
WP_011064602 100 VISKASDLKADALVSECMAVKPDYQIVFQDKILQANIGLIVNVLEDHMDVLGPTLKEVADSFSEAIPHNGDLIINDS--P 177 Oceanobacillus ...
WP_003020724  99 IMFKARRAKADAIVIECMALQPLLQSLCELKLIKATHGVLTNARPDHLDVMGPTERDVAKALAATVPVGAKYFTAED--I 176 Francisella tul...
WP_011235626 100 TLKRMAALKPEIVVMECMALQPQYQSLSELRMVRSTVGVITNARADHLDVMGPGENDVALALAGSTPLKGDLFTAER--D 177 Idiomarina loih...
WP_011461797  96 VVRKAARLGASAFVTECMAVNPDYQITFQEKLVKANVGVIVNVREDHMDLCGPTLDFIAESFTATIPRNGTLVVADS--R 173 Desulfitobacter...
WP_005903746  95 VITWASKEKAEVLILECMAVKPELQYVCENKILKSDIVAITNVREDHLDEMGDSLDKIADSLSNTIPKKATFFTADK--N 172 Fusobacterium n...
WP_000007606  95 FLRFAVNNDAQAIVLECMAVQPQYQRDSEELLICATHGVITNIRPDHWEWT-DTEEKILEGFKKTIPNNGILIYGKN--Y 171 Leptospira inte...
WP_011118210 177 SLSVMK----------------EACDDRASQLVVTtadDANNITQDELAQFSYLEHAE---NVALALKVCQSMGVARDVA 237 Rhodopirellula ...
AAA22286     175 YLDYFK----------------EVAEERNTKVIVA---DNSRISEEFLRKFDYMVFPD---NASLALAVAEALGIDEETA 232 Bacillus anthracis
WP_011201748 190 YTDFFK----------------QIAKERNTKVIVA---DNSKITDEYLRQFEYMVFPD---NASLALGVAQALGIDEETA 247 Bacillus lichen...
WP_011302326 174 YTDFFA----------------KVAKRRKTKLIVV---NKEEVPESFLRKFGYIVFPD---NVAIAMGVAEALGIDRDIA 231 Staphylococcus ...
WP_011274856 174 YTKFFA----------------KEAKKRKTKLIVV---DKDEVPESYLRKFPYLVFPD---NVAIALGVAEAVGVDKETA 231 Staphylococcus ...
WP_011064602 178 YVPHFR----------------QMAKQRNTKVHVC---DTSIISEDFLKKFEYMVFPE---NAALAIAVADVLGIDHETA 235 Oceanobacillus ...
WP_003020724 177 HLDFFE----------------YACKDRGSELIAAtaqDAEKISDEEINKFVYSEFKI---NVALALKVIDDLGIPREIA 237 Francisella tul...
WP_011235626 178 LLDVFK----------------HSCNDRKSELHGVtedEVNAITDDTMKRFRYAEHAE---NVALALNVCQHLGVDREKA 238 Idiomarina loih...
WP_011461797 174 YNDYFR----------------REAGKRNSRVLIT---DEKEIPDGYLEKFGYIVFPE---NIALALAVARALNIDKDIA 231 Desulfitobacter...
WP_005903746 173 YFNFFK----------------NRCEDKNTR---------AFLSKNIKNEYWEIDFPN---NIALAMDICKYLNVDEKIA 224 Fusobacterium n...
WP_000007606 172 IAESLKpnwnpsqksklnlsllEAASLKNTKLILA---EPELSKNQIETAFGYIRYPEhyeNVEIAVRVCETLGVSSKSI 248 Leptospira inte...
WP_011118210 238 LQGMWEAQPDPGAMRVH-VQEVHGNSWHFVNAFAANDPESTTRIWDAAYNYFPGVTQRVLVMNCRVDRADRSTTMAEAVA 316 Rhodopirellula ...
AAA22286     233 FRGMLNAHPDPGAMRIT-RFADQSKPAFFVNGFAANDPSSTLRIWERVDDFGYSNLAPIVIMNCRPDRVDRTEQFARDVL 311 Bacillus anthracis
WP_011201748 248 FKGMLNAPPDPGAMRIL-PLMNAKNPGHFVNGFAANDAASTLNIWKRVKEIGYPTDQPIVIMNCRADRVDRTQQFAEDVL 326 Bacillus lichen...
WP_011302326 232 LQGMLNAPPDVGAVEVK-YYNANNSTNVYVNAFAANEPQSTKAILNKVETYNYPYNKIVLILNCRSDRIDRTRQFCEDFI 310 Staphylococcus ...
WP_011274856 232 LRGMLNAPPDPGAVEIK-YFNANRTRNVFVNAFAANEPQSTKAILNKVESYNYPYTKKVVILNCRSDRVDRTRQFVENFI 310 Staphylococcus ...
WP_011064602 236 YRGMLKAWPDPGAMQII-PIGDKNKPSFLVNGFSANDPMSTLNIWERVKQLSYPTDDPVVIMNTRSDRLNRTEQFIKQVL 314 Oceanobacillus ...
WP_003020724 238 LKGMWEATPDPGAMTEY-NFNIKNAEINFANAFAANDPVSTKMLWDKLCAKYSGCDKKVLVVNCRDDREDRSKQMAEAAL 316 Francisella tul...
WP_011235626 239 LDGMVALEPEAGAMQVL-HVNYFKREIVFVNAFAANDPESTGRIWENMLEKHGEERRKIVLINCRADRPHRSQQMAEDIV 317 Idiomarina loih...
WP_011461797 232 LRGMLNANPDPGALMIH-PL-DKQEGSYFVNGFAANDPNSTRLIWDHITAMGYATANPMVIVNCRPDRVDRTLQFAGEVL 309 Desulfitobacter...
WP_005903746 225 LEGMRTYHKDPGSLKVLtYLNKKNFRIFFVNTLAANDPDSTEIILDRVCIKTYWNNERYLLVNNRADRLSRLKQFVNFTI 304 Fusobacterium n...
WP_000007606 249 LRGITNTVSDPGALKIL-EKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWSEFDSIILVFNSKQERPFRTIEFGKFLT 327 Leptospira inte...
WP_011118210 317 TWAP-ADRYVIIGSGTDIFlRRLLKRG----IHP-DKVICLGNSSGPELVESVLEsfrreermataprphfqsgtavaer 390 Rhodopirellula ...
AAA22286     312 PYIK-AEIVIAIGETTAPI-TSAFEKG----DIPtQEYWNLEGWSTSEIMSRMRP------------------------- 360 Bacillus anthracis
WP_011201748 327 PYIE-ASELVLIGETTEPI-VKAYEAG----KIPaDKLFDFEHKSTEEIMFMLKN------------------------- 375 Bacillus lichen...
WP_011302326 311 TDVE-FDTLICTGKSTQMV-TDVMKG------LPeKKYLNFEGKDIKEVERAVYN------------------------- 357 Staphylococcus ...
WP_011274856 311 DDVD-FDTLICTGKSTQMV-TDLMQ------HLPdKKYLNFENREFPEIEKAILQ------------------------- 357 Staphylococcus ...
WP_011064602 315 PNIQ-AETLVVMGDSTGLI-VEEYKKG----TFPvKNLLDLEKTSTEEIVRVLQP------------------------- 363 Oceanobacillus ...
WP_003020724 317 GWQK-QDLIVLIGTGTEVF-TSFYKKYakslNKPmTKVIVCEEMTPIQILEKTVD------------------------- 369 Francisella tul...
WP_011235626 318 KWSP-ADKYLLMGSGTFIF-VRNAVKY----GLDpEKLLVMENAEMTEITETILE------------------------- 366 Idiomarina loih...
WP_011461797 310 PQMD-IEILVAMGETVGPI-SEGVHTG----KIEpRQYINAEGLSPHEVYHMIKD------------------------- 358 Desulfitobacter...
WP_005903746 305 KFENrFDKILISGENKNLF-YKYLLKN----RIDkNRIIILSDEKYFENIE----------------------------- 350 Fusobacterium n...
WP_000007606 328 DFSG-LSKIYFFGSWQKLF-RSVYEG---------NADLTFYKKNIIFNFKEIF-------------------------- 370 Leptospira inte...
WP_011118210 391 aeemE--S-SAMMLMGIGNVAGPGMALADHF 418 Rhodopirellula baltica
AAA22286     361 ----Y--L-KNRIVYGVGNIHGAAEPLIDMI 384 Bacillus anthracis
WP_011201748 376 ----K--L-EGRVIYGVGNIHGAAEPLIEKI 399 Bacillus licheniformis
WP_011302326 358 ----E--S-QNALMFCVGNIHGPGKQIAEYI 381 Staphylococcus saprophyticus
WP_011274856 358 ----E--S-QNALIFCVGNIHGPGGRIAEFI 381 Staphylococcus haemolyticus
WP_011064602 364 ----Y--L-SDKTIYGIGNIHGGADELVTRL 387 Oceanobacillus iheyensis
WP_003020724 370 ----SnpA-NSYILVGVGNIKDIGMELVDYC 395 Francisella tularensis
WP_011235626 367 ----E--SgSSALVVGMCNIHGGGEEVARFF 391 Idiomarina loihiensis
WP_011461797 359 ----D--F-TGRMVFGVGNIHGGGEELVELI 382 Desulfitobacterium hafniense
WP_005903746 351 ---------DDSLIFAVGNICRLGKKLVDYF 372 Fusobacterium nucleatum
WP_000007606 371 -------S-KSNLWIGAGNYQGFGRVWLEKL 393 Leptospira interrogans
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