Conserved Protein Domain Family
SGNH_arylesterase_like

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cd01839: SGNH_arylesterase_like 
SGNH_hydrolase subfamily, similar to arylesterase (7-aminocephalosporanic acid-deacetylating enzyme) of A. tumefaciens. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.
Statistics
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PSSM-Id: 238877
Aligned: 23 rows
Threshold Bit Score: 204.039
Created: 16-Aug-2004
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:active site [active site]
Evidence:
  • Comment:by similarity to other members of this super-family
  • Comment:the active site resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases
  • Citation:PMID 7773790

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1              #                                                       #                
AAD02335      4 SVLCFGDSLTWGsdaetgg----rhshddLWPSVLQKALgpd------------vkVIHEGLGGRTTAYDDhtad----- 62  Agrobacterium tu...
NP_436343     8 TVLCFGDSNTHGqvpgrgpl--dryrreqRWGGVLQGLLgpn------------wqVIEEGLSGRTTVHDDpieg----- 68  Sinorhizobium me...
ZP_01075501   3 KILCFGDSNTWGtkpegg-----ryddheRWSFLLGVYLnmpssdsinqeteskylVMEAGQPNRTLIKNApfd------ 71  Marinomonas sp. ...
YP_730806     5 SILCFGDSNTWGmapdgsg----rlpfktRWPNRLQQILnqqnln------hqswnVIEQGLNSRTWVMDDplgavnygg 74  Synechococcus sp...
ZP_01154811   3 TLLCFGDSNTHGsppangpgpyaryghgvRWPSVCAGALger------------weVIEEGLPGRTAQFDDpgmg----- 65  Oceanicola granu...
ZP_01123955  10 TILCFGDSNTWGfnpdgsg----rfpqptRWPNQLERALnqtrp-------dlpwrTVEEGLNSRTWLHDDaigtanygg 78  Synechococcus sp...
YP_341681     4 NILCFGDSNTWGlnpqtgk----rfsatvRWPAKLAVKLgan------------ftIIEAGQPNRALVNNPpfa------ 61  Pseudoalteromona...
ZP_01134367   3 KIICFGDSNTFGitpqgg-----rfnaneRWPTLLETLLnqttt-------skqfhVIEQGQPNRTLVHNPpfh------ 64  Pseudoalteromona...
ZP_01446757   6 RILVYGDSNSWGylddgs-----gerfqdRWPVEMDKHLsydl----------sitLIEECLPARTTNLADpelg----- 65  alpha proteobact...
CAK99267      4 NIATLGDSLTFGylpmgtg----kmadadNWPVKLENLLtkyyq-------treieIQTDAQPGRTIIKPLidfg----- 67  Spiroplasma citri
Feature 1                                    #                                                  
AAD02335     63 -cdrNGARLLPTLLhshaPLDLVIIMLGTNDlkpsihg----------saivamKGVERLVKLVRNHvwqv------pdw 125 Agrobacterium tu...
NP_436343    69 -slkNGRIYLRPCLqshaPLDLIIIMLGTNDlkrrfnm----------ppsevaMGIGCLVHDIRELspgr-------tg 130 Sinorhizobium me...
ZP_01075501  72 -gdkSGLTYLKPLLai-hEPELVIIMLGTNDlkakfnl----------spadigAGAGTLIEQIQAFsqeai-----shs 134 Marinomonas sp. ...
YP_730806    75 dyscNGRQDLSMILhsckPLNVVLLALGCNDckshlhl----------speeitSGAKILIHDIRMSyqcgp-----rys 139 Synechococcus sp...
ZP_01154811  66 -ahmNGWPALRIALeshgPLDVLAVMLGTNDvktrfap----------tparvtAGIAGLLDIALSEamqe-------rh 127 Oceanicola granu...
ZP_01123955  79 dyscSGRSGLMTALhshkPIDVVILALGCNDckgylnl----------saeqitAGARILIHDTRRAlncgpr---ldpp 145 Synechococcus sp...
YP_341681    62 -gelSGVTYLQSYLne-lEIDLIIIDLGTNDlknrfsl----------nvhdiaAGLTALIDSILNFyeqs------nap 123 Pseudoalteromona...
ZP_01134367  65 -gdkSGLRYFKNCLld-hQPDLALIMLGTNDlkrkfcl----------daseiaSGLNALITASLALq------------ 120 Pseudoalteromona...
ZP_01446757  66 -ssfNGEATLEAVLlshqPLDHVLIMLGTNDlkakf-------------drninDIAEAIVNLAEIArstpagrggwfsd 131 alpha proteobact...
CAK99267     68 fpqdNGMDNLSVLYqkahPIDLFIIFLGTNDyfgydayaklkeipdyqietkivDSLGELVNKMESLhkdn------kek 141 Spiroplasma citri
Feature 1                                                                           #  #        
AAD02335    126 eAPDVLIVAPPqlc---etANPVMGAIFRDAIDESAMLAPVYRDLADDLd---cGFFDAGSVarttpvDGVHLDAENTRA 199 Agrobacterium tu...
NP_436343   131 nDPEIMIVAPPpm----leDLKEWESIFSGAQEKSRKLALEFEIMADSLe---aHFFDAGTVcqcspaDGFHIDEDAHRL 203 Sinorhizobium me...
ZP_01075501 135 sATKILLVSPPei-----kEVPPYVSVYAGGAQKSQLLAHEFATQAKQYq---cDFLDANQVikssdvDGIHWGAQAHES 206 Marinomonas sp. ...
YP_730806   140 nHPPTIVLVTPgvi---qtTPQSLAWGFKGAAEKSRMLPSLYRNLAEQEs---vFFFDTQAIaetsplDGVHFGADQQDS 213 Synechococcus sp...
ZP_01154811 128 gGLRVLLVAPPkv-----vLAGLDAGEFHGAEEVSAALPDHYRALAEARg---cAFLDANDVisvsplDGIHFDETAHGA 199 Oceanicola granu...
ZP_01123955 146 tSPRIILMTPPai----riTPQSLTWGFEGAELKSQALAEHYCQLAAELd---vACFDVQPVanpstlDGVHFDAQAQAL 218 Synechococcus sp...
YP_341681   124 gSPKILILSPAhv-----rEVGSYAGVYKGAEQKVVQLAAAFANVASIKq---cSFYDLARIvsvsneDGVHLDEKQHQK 195 Pseudoalteromona...
ZP_01134367 121 pALKVLIICPPpi-----lEVGSYAQIYLGGAVKSLALESAYQAVAKELn---cAFFAASSVvnscpiEGIHWSAKQHTQ 192 Pseudoalteromona...
ZP_01446757 132 qTPNVSVICPLiigqrvsdLKWDRFEEWVGAYEKSILLVDTLKRACNAVn---iNMIDGNQFgssselDPIHWDKENHQR 208 alpha proteobact...
CAK99267    142 vNYQVLVVCPPkv-----lTLHDGELLTSLPDAYQKYFAKLNIPVVNLQlaanpHPEDQSKY------DGIHYTSMETMA 210 Spiroplasma citri
Feature 1                   
AAD02335    200 IGRGLEPVVRMM 211 Agrobacterium tumefaciens
NP_436343   204 LGEALAQEVLAI 215 Sinorhizobium meliloti 1021
ZP_01075501 207 LALSIAEYIKQR 218 Marinomonas sp. MED121
YP_730806   214 IAAGLAELITAI 225 Synechococcus sp. CC9311
ZP_01154811 200 LGKAVAEQVTRL 211 Oceanicola granulosus HTCC2516
ZP_01123955 219 IAAGLAACICQT 230 Synechococcus sp. WH 7805
YP_341681   196 ISDALETIIREF 207 Pseudoalteromonas haloplanktis TAC125
ZP_01134367 193 LAQALVKVVIEL 204 Pseudoalteromonas tunicata D2
ZP_01446757 209 FGQKMAKAIQAF 220 alpha proteobacterium HTCC2255
CAK99267    211 VAQAIFDVIIAE 222 Spiroplasma citri

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