Conserved Protein Domain Family
T3SS_SctB_pilot
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NF038055: T3SS_SctB_pilot 
type III secretion system translocon subunit SctB
One SctB and four SctE subunits, located at the tip of the type III secretion system (T3SS) injectosome, combine to form the translocon (translocator pore) in the membrane of targeted cells. Species-specific names for this highly variable component of T3SS include YopD, EspB, IpaC, SipC, etc.
Links
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Statistics
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PSSM-Id: 411647
Aligned: 14 rows
Threshold Bit Score: 196.491
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_005450225   2 LDKIG--NTGRADLYGLGELGKTTKAEKAPETKTEAAaIRGNSEAAVSGPKHYQLDGPKAPAIGDQARVVEKLMSALApt 79  Vibrio
WP_017107447   2 LEKIS--NTGHAALHGLGELDKTSHTEKTPETKIEAAvIRASAESKVTNTKHYQLDGPKAPAFGDQASAVAKLMDGLAst 79  Vibrio
WP_009842669   2 LVESG--VNVKIADVSLDELDQISQAKKSAETKIEAAsLQGSHE---LSTRKHQLDTPNAAALGVQAASVEDLIDAMKpt 76  Vibrio sp. AND4
WP_004745549   2 ANEVNniTAGYTKIFDLVDNFKTEAGETRAITKQEAAeLKTTVQSWANDLKNYQLSVPSGQVNGQMAMAAEKLVGELSta 81  Vibrio tubiashii
WP_019446811   2 INSDYanGVTRTAPLTEVQAGEAQQVRSAATAHEAAVsTRPQGSENKSVPTLPR------PSIPFDTKGVTQMVAQLD-- 73  Aeromonas
WP_005302429   2 INSDYanGVNHTSLLPEMRTGESQQVRHPETIHEAAGsGGQRAAENKSLPVLPR------PSVPFDSKGVTQMTEQLE-- 73  Aeromonas dhake...
WP_003109504   2 IDTQY--SLAATQAAIPSEPIAPGAAGRSVGTPQAAAeLPQVPAARADRVELNA------PRQVLDPVRMEAAGSELD-- 71  Pseudomonas
WP_011147896   2 KINDN---ASSQGVTSSNGVEVGTDNFVSTPTAHEAAiQQPEKTRLTDKVELIV------PKQGLDPSRLGNVGQELN-- 70  Photorhabdus
WP_011117631   7 TDSPIitTGSQIDAITTETVGQSGEVKKTEDTRHEAQaIKS-SEASLSRSQVPELIK---PSQGINVALLSKSQGDLN-- 80  Yersinia entero...
WP_011787387   2 TTITNvrDIPGFNQSQYDTLVATARGQNIDPAAIDMAlLQAVNAGSNFSAALKSVTGDL-PRLSLPHNNALSHLGSLD-- 78  Desulfovibrio v...

WP_005450225  80 vnllmqtte----------------------------------------------------------------------- 88  Vibrio
WP_017107447  80 tnllmqite----------------------------------------------------------------------- 88  Vibrio
WP_009842669  77 atllmqttd----------------------------------------------------------------------- 85  Vibrio sp. AND4
WP_004745549  82 lsninsvgslatgtlsgsllisslekikpvadfvlgridtvlagnpvseklmaqmaplmddlvtaivqsaageanksnnl 161 Vibrio tubiashii
WP_019446811     --------------------------------------------------------------------------------     Aeromonas
WP_005302429     --------------------------------------------------------------------------------     Aeromonas dhake...
WP_003109504     --------------------------------------------------------------------------------     Pseudomonas
WP_011147896     --------------------------------------------------------------------------------     Photorhabdus
WP_011117631     --------------------------------------------------------------------------------     Yersinia entero...
WP_011787387     --------------------------------------------------------------------------------     Desulfovibrio v...

WP_005450225  89 ---------------------------------------kalngeqviksPSDAISQSLSLLTLLYQVSKLSREQQVLQR 129 Vibrio
WP_017107447  89 ---------------------------------------nalagkdvaksSSEAISQSLSLIALLYEVSKLTRDQQVQQR 129 Vibrio
WP_009842669  86 ---------------------------------------kalkgeqvihsPSDSISQSLELVKLLYQVSILSRDQQTQQR 126 Vibrio sp. AND4
WP_004745549 162 ddmlprltqavesvktmlngteegrkltqelnsligkmtnnagqvadaedSSNSIADGLALIVLLYTLSKLSRQQQVQQR 241 Vibrio tubiashii
WP_019446811  74 --------------------------------------------------------SAMDMMSLLFKLARQAREEGLQVR 97  Aeromonas
WP_005302429  74 --------------------------------------------------------SVMDMMSLLFKLARQAREMGLVQR 97  Aeromonas dhake...
WP_003109504  72 --------------------------------------------------------SSVELLLILFRIAQKARELGVLQR 95  Pseudomonas
WP_011147896  71 --------------------------------------------------------NTLDMMSLLFEIAKRMRELGILQR 94  Photorhabdus
WP_011117631  81 --------------------------------------------------------GTLSILLLLLELARKAREMGLQQR 104 Yersinia entero...
WP_011787387  79 ----------------------------------------------------MAPSPGATLMSLITSMASEERKQNAQMR 106 Desulfovibrio v...

WP_005450225 130 EIAVEANVASLKSQAQELNNSAKAMIAMAVISGVMAGVTAIMGAVGSMKAGKKIKQEAAGNKAFKGQQANLDAKMAEIKN 209 Vibrio
WP_017107447 130 EIAVEANVASIKSQAEELNSAAKAMLAMAVVSGVLAGATAIIGAIGSFRTGRELSSEVAHNKVLQTQKSGFEQAEELMAS 209 Vibrio
WP_009842669 127 EMKVETTVSSIKSQAEELNNSAKAMVAMAIVSGVLAGATALIGGIGHFKTGTKIKSEAANNNILKTQEIGFDQVQELMNN 206 Vibrio sp. AND4
WP_004745549 242 EIAVDATVTSQKNQADEQRSAAWAMIGMAIVAGVMAGLTVAAGAFGAFQSGKKIGKEMSANAQVNTQQKGMNQVDELLKK 321 Vibrio tubiashii
WP_019446811  98 DIENKLVISNQQAQVDEMRHGAKLMIAMAVVSGVMAGFSAIMGGISLGKGAKTIKQQQSLDGKIAGREALIDAKVDSLSK 177 Aeromonas
WP_005302429  98 DTENKLVIGHQQAQVDEMRHGAMLMIATAVVSGVMAVASAVMGGFSMAKSAKTIKQDKALNANIAGRQQELKQIGDIKKT 177 Aeromonas dhake...
WP_003109504  96 DNENQAIIHAQKAQVDEMRSGATLMIAMAVIAGVGALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDAKMQALGK 175 Pseudomonas
WP_011147896  95 DTENKASIDAQKSQVDEMRHGAKLMIAMAVVSGLMTLGSGLIGSFSSVKNSQAVKQQKTLESNIAGRNKLIESKLQQLGK 174 Photorhabdus
WP_011117631 105 DIENKAAITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQEQILNSNIAGRDQLIDTKMQQMSN 184 Yersinia entero...
WP_011787387 107 IEETKAIVEKIMDQADEMRNKAIVQLVMGVVSGAISIAQGVAS--------------MSMQASAMKQLDGFQTGSQIATQ 172 Desulfovibrio v...

WP_005450225 210 TkGFegAKAKRGEMHREANMIRTDMDHIKADTTAYGRKFDKQMGNNQATNSVIQALTQMANSASNVEQTKAQARSKEDEV 289 Vibrio
WP_017107447 210 G-NM--STKHQDQVRKAYAAAKENIADTSSSLTSTGRKFEKMAGSNQARNAVLQALGQMGNSAASVEQTKAQARSKEDEV 286 Vibrio
WP_009842669 207 K-SL--SDVQQKQVMNAYNFARGSLSDTKNVLQTGGRQFDRGMHVTQSANAMLSSSGQTANSVLNAQQTEAQARSKAEEA 283 Vibrio sp. AND4
WP_004745549 322 T-DL--PEHERVQLTKLKEEGTKNLTEGNQYLQTNNHKFDRMTGINQALTAFVQTLGQFGNAIANYSQAESQARSKEDEV 398 Vibrio tubiashii
WP_019446811 178 Q-GQ---QVDRADVGKVW---KQDQVADSNASRLLDKKFARTSERGQVFNTVTQSVGQMSNSAVQVAQGDSQANAKEDEV 250 Aeromonas
WP_005302429 178 A-GL--------EMGDAGQDLTARIKNDKAALLTLNKKFDANNSRQQLAGTVTQSVGQMSNSAVQVSQGTSQAEAKEDEV 248 Aeromonas dhake...
WP_003109504 176 T-----SDEDRKIVGKVW---AADQAQDSVALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQASAREEEV 247 Pseudomonas
WP_011147896 175 S-----SDADRAAIGKVW---NVAQDADKSTLKSLTLVFESRNSNQQLLTSVMKSLEGMSNNSVQVEQGLSQAKAKEHEV 246 Photorhabdus
WP_011117631 185 T-SD--KAVSREDIGRIW---KPEQVADQNKLALLDKEFRMTDSKANAFNAATQPLGQMANSAIQVHQGYSQAEVKEKEV 258 Yersinia entero...
WP_011787387 173 K-GL---PNMAKSFDAMYQSGMSKLTAQQNALNSG------FTAGNSAVAGINQAVGGFFDAAIKEMDGDVERMRASRDA 242 Desulfovibrio v...

WP_005450225 290 LATRAQASKQKADENVGFQEGLLKELRELFRSIADSQNQAWRASIPTV 337 Vibrio
WP_017107447 287 LATRAQSDKQKADEYIGFQEGLLKELRELFRSIADSQTQAWRASTPTV 334 Vibrio
WP_009842669 284 ETTRSQAGQQAASDNKAALDNLLKELLTIFRSLSDSLNQTWKAAARMM 331 Vibrio sp. AND4
WP_004745549 399 QATQAQAEKQKADENVSFQEGLLKELRDLFRSIADSENQAWRASAPTV 446 Vibrio tubiashii
WP_019446811 251 DATISQSEKQKAEDNMSFNANFMKDLLQLMQQYSQSQNQAWKAAFGVA 298 Aeromonas
WP_005302429 249 KATISQAEKQKIEDNMSFNVNFMKDVLQLMQQYAQSQNQAWKAAFGVA 296 Aeromonas dhakensis
WP_003109504 248 NATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV 295 Pseudomonas
WP_011147896 247 GSSIAQHEKQKSEDQISLNNNFMKDVLQLLQQLYQNHVQALRAATGVV 294 Photorhabdus
WP_011117631 259 NASIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV 306 Yersinia enterocolitica
WP_011787387 243 MKQLDDALAQ-----------LIQKTLSGMDAIQQNMNQTRTRILG-- 277 Desulfovibrio vulgaris
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