3W7B,3OBI,3NRB,3N0V


Conserved Protein Domain Family
PurU

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COG0788: PurU 
Formyltetrahydrofolate hydrolase [Nucleotide transport and metabolism]
Formyltetrahydrofolate hydrolase is part of the Pathway/BioSystem: Purine biosynthesis
Statistics
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PSSM-Id: 440551
Aligned: 541 rows
Threshold Bit Score: 266.916
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3W7B_A         1 MEEARLLVTCPDRPGIVAAVSGFLYAHGANITDLQQHsTDpeGGTFFMRVAFTASHl--DLARPALERAFQEVvASRFQM 78 
WP_012910963   1 -mHVVITAVGPDNVRLADPIIHYVTGQGANIAEIQMY-DHddEALFAMLLRIHLPEe----KLPQLREALAQI-SEATKL 73 
WP_012945732   3 RERTEITIVGNDNSEIIADVTSLLFERDVDIVDLDQA-VR--EGTFRMGMQVDASEm--SVSREQLREDLDAL-GDEFGV 76 
WP_013108474   1 -mQVVITAVGPDNVGLADPIVHYVTGAGANIHEIQMF-DHdaEKQFSMHLRIEWPGv--PSSVAQLRSAMDQI-GALKSL 75 
WP_013630134   1 -mQVTITAVGPDNRGLADPIVHYVTGAGANIYEIQMY-DRdnEHLFAMLLRMEWPDg--QEPVGQLRERLQEI-GRLKGL 75 
WP_014435921   3 QIRAVISVSGQDQKGVVARFATYLAGHGVNILDLEQQ-VA--GGRFLMDMLVDLAEldpETGLERLIPELVAE-GGQIGM 78 
WP_015322478   3 RDATEITLIGEDDSGVIAELTTFLVERDVELLDLDQA-DR--EGTFRLTARVDTASm--ALSRSTLRAELRAL-GDEFDA 76 
WP_049954891   3 IELTEITVVGDDDTGLLAEITSLLFEHEINIEELDQA-VK--DDLFRMTMHVDTTGm--DCSQSELQSELEDL-CDELGV 76 
WP_075092322   1 -mHVTITAVGPDNRGLADPIVHYVTDAGANIHEIQMY-DHdaEQLFAMLLRVEWPEs--AGAVSTLREAMRDI-GERKGL 75 
WP_077025195   1 -mQVTITAVGPDNKGLADPIVHYVSGAGANIYEIQMY-DRdtEHLFAMLMRIEWPDe--MGSVAKLRDHLQQI-GNTRNL 75 
3W7B_A        79 QWRLAYAS---ERKRTAILVSKPAHALLELLWRyrVGELPMELRLVISNHPDHREEVERFGIPYHHVPVekGRKEEAEER 155
WP_012910963  74 SIRVWSPEeraSRPRLALCVTYRTEPPLAILRAirDGQIRAEAAVMIGNRGACRGIAEQFGVPWESIGD--DSGKANDDQ 151
WP_012945732  77 DVTVRFPSn-cEDRSIAVLVTKESHCLEALLERweNDELGADIGVVIGNHDTLRPLAAEYDVPFHDIGD--ENGTPDEDE 153
WP_013108474  76 AIRVWSRDehaRLPRLAICTTYRPEPALAILRAirDGRLKAEAAIMLGNREACRGVAEQFEVPFVNIGN--AKGEPDDSQ 153
WP_013630134  76 SVRVWARDehkRPPRLAICTTYRPEIPLALLRNirDGRLKAEAALVLGNRDACRSLAEQFDVPWESIGD--AKGNPDNDR 153
WP_014435921  79 DVRVALASs-pKDQAVAVLVSKEQHCLDVLIDRweKDGFRGRIACVLGNHPDLQEVAAEAGLPFAWKAS--TDKAAHFAW 155
WP_015322478  77 DVQVRYPSg-cENQSIAVLVTKESHCLEALLEAwdDGELGADLEVVIGNHDDLRPLAAEYGVPFHDVGD--ESGTPDEDE 153
WP_049954891  77 DVRIRFPSe--GAQSLAVLVTKESHCLRRLLEEheSGDLSADIDVVLGNHSDLESLAEEYNVPFHDIGD--EDGTPDEDE 152
WP_075092322  76 SIRTWARDerkDLPRIALCTTYRPEPARAVLRDirDGRLKAQCAVMIGNRNACRGLAEDFGVPFHNIGK--G-GDPDYGE 152
WP_077025195  76 EVRVWARDehqRLPRVAICTTYRTEPPLAVLRAirDGRLKAEAAVMIGNRNACHSVAEQFEVPWLNIAD--SKGVPDYSK 153
3W7B_A       156 ILALLEAEGVELVVLARYMQILSPGFVERFPm-RIINIHHSFLPAFAGADPYRQAYERGVKLIGATAHYVTEELDQG-PI 233
WP_012910963 152 MVDLLDRYEVDYVVLARYMRVLPAASCWKYAggRIINLHHGLLPSFPGLRPYHDAYAGRMLTFGATCHFIVPELDAGnQI 231
WP_012945732 154 LLDLLAEYEIDLIALARYIRILSPEVVFRYEd-RIINVHPSLLPAFPGAAAYRQALEEGVRIAGVTAHYVTTDLDQG-PI 231
WP_013108474 154 FVRVLDDADVDYVLLARYMRVLPPNVCWQFAg-RIINLHHGLLPPFPGFHPYEDAYARRMLTFGATVHFIVPELDAGnQI 232
WP_013630134 154 FVEVLDEYEIDYIILARYMRILPPRLCWEFAggRIINLHHGLLPSFPGFRPYHDAHSHHMLTYGATAHFIVPELDAGnQI 233
WP_014435921 156 LGEQLQEHGAATVVLARYMQIVPPDLVAAYPs-RIINIHPSLLPHFPGANPYRRAWEAGARVAGCTAHYVTEQLDEG-PI 233
WP_015322478 154 LLELLAEYGIDLITLARYIQILSPEVVFRYEd-RIINVHPSLLPAFPGAAAYRQALQKGARITGVTAHYVTTDLDQG-PI 231
WP_049954891 153 LLRLLDDYQIDLIALARYIRILSPDVVFRYQn-RIINVHPSLLPAFPGARAYMQAVEGGVRIAGVTAHYVTPDLDQG-PI 230
WP_075092322 153 MTRLFDEYQVDYMVLARYMRVLPPRICWEFAggRIINLHHGLLPSFPGFRPYQDAYVRHMLTYGATVHFIIPELDAGdQI 232
WP_077025195 154 MESLIDEHEIDYVILARYMRVLPADICWKFAggRIINLHHGLLPPFPGFRPYEDAFQHHMLCYGSTVHFIVPELDAGnQI 233
3W7B_A       234 IEQDVVRVSHRH-SVREMKRLGR-ELERTVLARAVRWHLEDRILVHENRTVVF 284
WP_012910963 232 IQQSTFTVPPGT-KLEEIIRIGQeDNEPRCLVEGIRRVVDREVQLHFHRVIAT 283
WP_012945732 232 ITQRAFNIPADA-TEADLKERGQ-PLEADALAEAIRLHLEDEITTEGGQTRVV 282
WP_013108474 233 IHQSTFTVPPGT-PLADIKRQGEtDHEPQCLLEGVRRVVDREVELHFQRVIRR 284
WP_013630134 234 IHQTTFTVFPGT-PLEEIIRQGEsDNEPTCLVEAARRVIDREVELHFHRVVRR 285
WP_014435921 234 ILQDVFPIDVGRdGAEDVRAKGQ-KLEGRILAEAVRMHLDAKLVVVDGKVVFR 285
WP_015322478 232 ITQRAFNVPADA-TEAELKARGQ-PLEADALLEAIELHLEDELVVADGRTELE 282
WP_049954891 231 ITQRAFNVPDGA-TEAELRQIGQ-PLEAEALLEAIKLHLNDELMVGRGRTHAT 281
WP_075092322 233 IHQGTFNVFPGT-PLEEITRIGEtDNEPNVLSEGLRRVIDREVELHFHRIIKN 284
WP_077025195 234 IHQGSFNVPPGT-PLEDIKRQGEsDHEPNCLVEGLRRVIDREVELHFHRIVKT 285
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