Conserved Protein Domain Family
HMG-box_HMGXB4
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cd21982: HMG-box_HMGXB4 
high mobility group (HMG)-box found in HMG domain-containing protein 4 (HMGXB4) and similar proteins
HMGXB4, also called HMG box-containing protein 4, high mobility group protein 2-like 1 (HMG2L1), or protein HMGBCG, is a non-histone chromosomal protein that negatively regulates Wnt/beta-catenin signaling during development. It plays a role in the hematopoietic system.
Links
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Statistics
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PSSM-Id: 438798
Aligned: 6 rows
Threshold Bit Score: 116.994
Created: 8-Apr-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative DNA
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         ## #####  ##      #              ##  #  ##      #   #  #   #  #
Q9UGU5       407 KKKNMSAYQVFCKEYRVTIVADHPgi---dFGELSKKLAEVWKQLPEkDKLIWKQKAQYLQHKQ 467 human
Q6WKW9       359 KKKNMSAYQVFSKEYRVSIIAEHPgi---dFGELSKKLAEVWKQLPEkDKLVWKQKAQYLQHKQ 419 African clawed frog
AAH46014     263 KKKVLTAYQIFYKEYRNSILEEHPgl---dFGDLSKRLADAWKQLPEgDKQVWRERSEYLQRRQ 323 zebrafish
EMP33162     411 KKKNMSAYQVFCKEYRVTIVAEHPgi---dFGELSKKLAEVWKQLPEkDKLVWKQKAQYLQHKQ 471 Green sea turtle
XP_006006942 417 KKKNMSAYQVFSKEYRVNIVAEHPgi---dFGELSRKLAEVWKQLPEkDKLVWKQKAQYLQHKQ 477 coelacanth
XP_007908466 402 KKKIMTAYQVFCKEYRVNIIAEHPaigkkdFGELSKKLAEVWKQLPEkEKLAWKQKCLYLQHKQ 465 elephant shark

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