Conserved Protein Domain Family
VirD2

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COG3843: VirD2 
Type IV secretory pathway, VirD2 component (relaxase) [Intracellular trafficking, secretion, and vesicular transport]
Statistics
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PSSM-Id: 443053
Aligned: 81 rows
Threshold Bit Score: 475.991
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011456642  23 ERVVRPARGFLADVHRAIRRAGGDPNKLAGRGKASGRYNARGRGAKVVAELKGRNQWSRSANGTRTRARRVTVKARIVKL 102
WP_015826529   5 KPFTPRLGHIKDGGQAGSKRFSKQIAKRAAKLAQTSGPKGRVRASFVRGATASAVSSVRHTSYPFSRMRRAVVKVHIARA 84 
WP_013041101   8 APRLGRQGASRGPKARRYASSVVAAANLARGAGPGRKGRAGFSGHRYGRGAGIGRLLSVGTSNAFFRRRRVIVKARLVRL 87 
WP_013300173   5 DEFTPRLGRPRDVGAAGGRRFKSQLTRAAKRLSSSTGKTVFSGAQIARGSGAGRASQFRQSPYPKFRMRRVVVKVHIARA 84 
WP_013301516   3 DDFDFVPRLGKIRSKGKAKTQLKRLKRVVAKGRLGSRGRKGLPPGAVRHAGRGKVQAALARHWSSQQARRVIVKVHIARA 82 
WP_013479933   6 YFEPKLGRIRSQTAKTPRSFRSSVIGAVQRAGGFKRAGNAAAKGGGNYGRGAGVGRVLTASSARGRTARRVVVKARFVRL 85 
WP_069707830  16 GAGRPRSFVGQVIVAGGLQTGRRNGVSASRTGSGRGARTRRFDGSRIGRGAVAGRLLASRRAGDPLRARRVVVKTSLTRL 95 
WP_066962680   5 DFDPKVSGKRTKSGKKAASYAGRIIAATRLAGKASGVRSRRFDGSRIGRGASMGRLLSSRDRLAGFRARRAIVKTRLVRL 84 
WP_121047036   4 DDEFTPKLGKPKARGKGRKYLGAVVGTAARAGKKTGVRSTRYDGSRIGRGASIGRILSSRDRLAGFRSRRAIVKMSYTHI 83 
WP_121052446   5 EFTPRLGRMRGKAGEPRYLSQVMKAAARAGKRGPGTGRRGSFDGSRIGRGASVARVLGFHDRLAGFRARRVIVKTRLVML 84 
WP_011456642 103 NPQrgaargrsfvSAKAVDAHLRYLQRDGVTLDGEKGQVYARDDDIADGRDFLDRGRGDRHQFRFIVSAEEGVELDNLRQ 182
WP_015826529  85 GYVg---------GAKAFGEHISYIERDGVDRDGNKGQSYDRDHDQIYTKDFKERSAEDKRQFRLIVSAEDATQIPDLKV 155
WP_013041101  88 GGK----------GGNQAVDHLRYLQRDGTNRAGERSALYGPGEDHADGKAFLEKGNGDRHQFRFIVAPEDGDRYEDLKP 157
WP_013300173  85 TRGl---------GPAAFRAHLRYIQRDGVDRDGEGGELYGRDADRIDGSLFEQRSATDRHQSRFIVSPEDASELGDMKE 155
WP_013301516  83 SPT----------GVAGFAKHVAYIRRDGAGREGERGKLYDRSVDEADAKAFNNRADEDRRQFRLIVSPEDADQMKDLTR 152
WP_013479933  86 AGK----------GVRAATAHLTYLQRDGVTREGARGVLYGPDADRIEASDFMARCDGDRHQFRFIVAPEDAHLYEDLKP 155
WP_069707830  96 SGK----------GLGAARAHLSYIQRDGVTREGDPGDLYSARGDRVDGREFLERSCPDRHQFRFIVSAEDGDRYEDLKP 165
WP_066962680  85 GQK----------GMRTARAHLRYIQRDGVTREGAPGELYSADRDAADGNAFLERSGGDRHQFRFIISAEDGAEYTDLKP 154
WP_121047036  84 AGG----------GLPAARVHLYYLQRGGVSRDGGPGQLYSASEDTADGRAFLDCSADDKRQFRFIVSAEDGDQYRDLKP 153
WP_121052446  85 AGK----------GIRGARAHLGYIQRDGVTRDGAPGALYSEGRDIADGKAFLERADGDRHQFRFIVSAEDADQYPDLKP 154
WP_011456642 183 TTRDLMVQMEVDLQTTLDWIAVNHYNTGHPHSHIIVRGVTDDGKILNIAGDYIAHGIRERASELVTLELGRQTDLQVTDQ 262
WP_015826529 156 EIRGFMSGMEKDLKTKLDWIAVDHFDTGQPHSHVIIRGVDELGDPLAIDRRYLMTGMRTRLSSQLTDSLGLRRDIEILRS 235
WP_013041101 158 LVRRLMMQMEEDLGTRLEWVAVDHYNTGHPHSHILLRGVDQDGDNLVIARDYIGRGLRERAAELVELDLGPRSDREILVS 237
WP_013300173 156 TVRALMAQAEKDLGTRLDWVAVDHHNTGHPHTHIVVRGKDQLGRDLIIARDYLTKGIRERASAIVTDELGPRRDLEIARA 235
WP_013301516 153 FTREFISQVEKDLGRRLDWVAANHHDTGQPHVHIVIRGGNTRNGELLIDRKYITRGFRARAQELVTRELGQRRLREMAAA 232
WP_013479933 156 LTRTVMQQMEADLRTKLDWAAVDHFNTGHPHTHIVLRGRDDRGKDLVIAREYLSEGFRERVQAQVSLDLGPRSEREIAQA 235
WP_069707830 166 LVRRLMAQVERDLETDLDWVAVDHFNTGHPHTHIVVRGVDDRGRNLVIAPEYLKHGIRARAVEVVTRDLGVRLDSEIEAR 245
WP_066962680 155 YVRRMMTQVEADLGTKLDWVAVDHFNTERPHTHVMLRGIDDQGQNLVIAREYISHGFRERAAELVTLDLGPRTDREIEER 234
WP_121047036 154 LVRRLMTQVEQDLGTKLDWVAVDHYDTGHPHTHIVLRGVDDRGQNLLIGREYVSNGMRQRAIDLVNLDLGPRTTLEIEER 233
WP_121052446 155 FVRRLMHQMEQDLGTKLDWVAVDHFNTGHPHTHVILRGKDDRGGDLVIARDYISHGLRARAADIVNLDLGPRTDLEIEER 234
WP_011456642 263 LRREVHAERFTRLDKMLMAEQRiNSaFADLRPDKdmLETMKRNRALLIGRAQYLEKLGLALKIDPGVWHLRENAEPALRA 342
WP_015826529 236 QTKDINSDRLTRLDRDLDNLAS-DQ---DVLPTKaiSEGERFKQSFLRKRLTHLQNLGLAHQQK-DKWTFKIGWQDTLKQ 310
WP_013041101 238 RRAEITQDRFTSIDRSLLRIAD-GH-VVKP------VALDPLEHDLQASRLGRLVRMGLAEPLPTGRYRLDPDLETVLRA 309
WP_013300173 236 QERDVTAGRMTRLDAKLEQLAR-DG---DLTRPGgmSKLSRFDRTLIQRRLEHLRGMGLASARGDGAWALEEGWKERLQT 311
WP_013301516 233 RSNEAEREALTAIDHDIAARLS-DG---RYTPESerGGLSRFDGALVNRRLRFLRTLDLARRREDGRWTLKEGWQETLRA 308
WP_013479933 236 LQAEVTQERLTAIDRQLRREAD-DRgHVLA------GYSDPVKSAARSGRLVKLEALGLAEKLPGGRWRLDPELETTLRQ 308
WP_069707830 246 LRHEVTQERLTPLDRGLIARMG-ADrIVAP------SARKPEIAALEAGRLQTLERMELAAPSGAGSWQLAEGIEQTLRE 318
WP_066962680 235 LRHDVDQERLTAIDRRLLRRMD-ADrVVTA------AENDPVQQSLAAGRLRKLKAMGLAEDIGGACYQLADGLEDTLRH 307
WP_121047036 234 LRHDIGAERLTAIDRRMVRDMD-ADrTLGQ------SMRDPFQQSLRTGRLRKLEDMGLAEEIGGGRWRLAEGLEKTLRG 306
WP_121052446 235 LRSDTGAERLTAIDRRLIRDMD-EMrIVSA------ADSDPFQQALRVGRLQKLARMDIATHLGGDCWRLDADLATTLRR 307
WP_011456642 343 MGERGDILKSIYRALEANdlevqrgEAQLSIHR---------------ETLQNRVVGRVPAKALsTDESRDRMQLVIDGT 407
WP_015826529 311 MGRRGDLIRSINDKYKNLd-----iSNKFKIYDr-------------aKPPSHGLVGRVLGSIP-LDELKDTHALLIEGI 371
WP_013041101 310 MGERGDIIRTMQREFSRLlle--rsSADRLIYDp-------------aEAGTPPLIGRILMHGL-AGELEDRHFLLIDGI 373
WP_013300173 312 IGREGDRIREIAAAFKTGd------GLSGRVYDp-------------tHENVPAIVGRVVTDGP-EEELRNRRYLILEAL 371
WP_013301516 309 LGRRGDIVRSLANLEGRKi-----dASRLHALPr-------------dLNSGGEVLGQLAATLP-GDELRNGTTALIEGL 369
WP_013479933 309 MGERGDIIKTLHRALKERgle--asLSETQMHFpsa----------ssSGLASTLTGRLIERGI-LEEHSDRHYVILEGI 375
WP_069707830 319 MGERGDIIRTMQRALGAArl----drAEVCIHGpdlevapnlahgregGAVIGPLVGRVVARGL-ADEHRDRHYLVLDGV 393
WP_066962680 308 MGERDDIIRLMQRELTARrld--rpGVDQVVt----------------TEVREPIIGRLIRRGF-SDEHRDRHFMMVDGI 368
WP_121047036 307 IGERGDIIRTMQREISARgr----eGGEQTIYDa-------------tDPQAAPVIGRVIARGL-ADELNDRHYLLVDGI 368
WP_121052446 308 IGERGDIIRTMQRDLSARnle--raGADCAIYDp-------------aAVGARPIVGRVLSRGL-ADEHEDRHYLLIDGI 371
WP_011456642 408 DGQVHQIELRADRCEDVGRGMIVSAAPPSTEPRVADQNILATRASDGTYSPSRHIEIARERKLSPEPERYVASHVRRLEA 487
WP_015826529 372 DGQTWSVDIGSTSKDKLPTKGHTVSVSHQDGKTKSSDQTIARIASLNNGLWSDSIHAVNDPASSPQYRQALKRRLEALRR 451
WP_013041101 374 DGRSHYVPVGKGDTGDLLPPSQAEGDSSQPGGAVVAIRPREAVVREVDRTIAAIAAGNGGRYDREAHRLHDPGARSDYVE 453
WP_013300173 372 DGERWHVGLGETLPGAVPPKDAVVEISPAARSPRASDKTIARIAALNGGLYSDSLHKAFDPASRADYRLAHIRRLEALRR 451
WP_013301516 370 DGRVWSIEMTEQEAAQLPKPGGIVSVGRKAVEPKPADITIAAIAERNGGVYSDELHEATDPSSSPAFRLAHKRRLEALRR 449
WP_013479933 376 DGRTHYVDIGQGSHTEPLPKEAILQVTPRRPDIREVDRTVLAVAQANGGYYTTEIHLRFDPSARRSFAETHTRRLEAIRR 455
WP_069707830 394 DGRSHYFDIGRGDAVAALPAGAIVRASRRELEIRAVDRTVAGVAAASGGRYSAHLHLTHDPATGTAFAETHVRRLEALRR 473
WP_066962680 369 DGRVHYLDIGRADAVPSVPENATVRIEPSRLGVTQADRTVDVVARAHGGRYSIDIHLAHDPQASEAYAASHVRRLEAMRR 448
WP_121047036 369 DGRSHYIDLGYGDAVGPTPQGSIVQIAPSRGDVRAVDRTVAEIAAANDGSYSTDLHLRHDPSATERFAEAHVRRLEAIQR 448
WP_121052446 372 DGRAHYAPLGKGEAAGMIPRDAIVRITPRAGGIRAADRTIAEVAAAHGGRYTIDAHLKHDPSATEAFAEAHVRRLEAMRR 451
WP_011456642 488 LRRSGIVERWDENHWSVPEDLPKQGLAYDRKRHGSGPRMTVLSPISLERQVTHDGATWLDRELAEQRQGSLRMAGFGAEA 567
WP_015826529 452 HKIVSRNKDGSWKVGQDYLAKVQAYETASLEALKIETKSHFKVDKLVQVQALTWIDEIDPRQCANTGFGGQAKQAILARR 531
WP_013041101 454 AHVRRLEALARAGDIPGRSGDGSWVIAPDHFGRVAAFERRQLRIQPVMIEMLSPVGVADLATAHAATWLDRTLLDGDPPQ 533
WP_013300173 452 AGFVTRDSDGRFAIGADYLAKAARFETARTGGVRVEVKSWLSVEAQITRRAPVWMDDVDRESLTGKGFGQDTASALSARR 531
WP_013301516 450 LGVVDRNVHGTWAVPSNFEERALQAEATKHGLAIDVRSWLPVEALAERHAETWLDQIDTDVLDGATGPFADELRKLLSIR 529
WP_013479933 456 TTGAIERLPDGRFRIDPDHLDKVLAYERKDVARLPVSISVQASRALDKLVGYKGVTWLDRQWVTGPSTEYAHTGFGRALR 535
WP_069707830 474 AGVPLTREDDGTWHIRPDHLAHVEAHEIAQLRQRPMTIDVLATGPLVALSRADAATWLDRELVEGGQSPIRDAGFGHELR 553
WP_066962680 449 ASAGPERLEDGSWTIPEDHLARAGAYAARQQRDRPVAVSVMSRAPVAELAAKDAPTWLDRELDGSGGSAVRDAGFGREVR 528
WP_121047036 449 VTGGTERRPDGTWTIAADHLDRVAAYEARIARDKPVVVEAVSPMPLDRLAGADAATWLDRRLAGDEAAPARDAGFGRELR 528
WP_121052446 452 ATRSVEREPDGAWIITPDHLEKVKRFEARQLRDRPVSVETLSAVPLEALAVAEAATWLDRDLIAGSPVPVRDAGFGREVH 531
WP_011456642 568 DQAMNRRKRVLVERGDAIDLGNGRIRTPKDLIRRLEGREVERVGRAMAEKQGLRWQPVEPGSQFDGQLTGSRQLSSGRFA 647
WP_015826529 532 LWLKEQGLMQAEQNSLSHQARTNLKAKEISSLANMETLNSARTFVSIEQTKSFNGKLERIVDAHQGKLALIGRDNSFTFV 611
WP_013041101 534 LRNAGFGRDMADALARRRQWLVEEGLAEQGEGEIRYRRDLLAVLRRRELLRVAGQLSRELALPFAETVEGEKLEGIYRRR 613
WP_013300173 532 AFLEREGWLGEDGRLKPGMRDQLAAEELKSAADRIEGKGAFLKLEDGMSISGVYERPVDLAQGRFALVTRSKEFTLVPWR 611
WP_013301516 530 KVWLRTEGYTLDQTGQPTAEDAERLKRTEFEKAMKTEGARMELSFAYPESWSEFSGTYSQHVELAQGRFAVITGRDRYTL 609
WP_013479933 536 SALQSRRQWLLEEGLWMPVTGQGGEALDPSVLKTLRQQEMTDVAAGLEASTGKTCRTVPRGGLVEGRLREIIETESEKYA 615
WP_069707830 554 GALRDRRDWLLTRDLAVREKDGVRLRPGALETLRRRELIRIGGELGVELAKPFVEARNGDRVEGKLTRRIDAISGPYAVL 633
WP_066962680 529 TALAARRQWLVEQQLADPDGTMLRFREGAMDRLRQRELAQAGDRLAQQVGKAFAPASTGERIEGVIARRVDLEGGSYALV 608
WP_121047036 529 QAETQRRQWLIAEGLADEHDGTVRLRANTLAVLQRRELLRIAGELSGELERPFAEAKQGERIQGTLRRRVDMTSGRFALV 608
WP_121052446 532 AARELRRQWLLAEQLAEEQDGRTIYRRNLLAALQRRELLRVGARLSEELRLPYKEAKTGDAVQGRLVRAVEMTSGRHALI 611
WP_011456642 648 MVDDGLGFSLVPWNDALEQRIGRQVSGVGMPGGGIDWTF 686
WP_015826529 612 PLRSDMGNSLGRDISLTRRGPSIDWKIGRQKGISR---- 646
WP_013041101 614 VDLISGRFAVLERSRDFALVPWRSVLERRVGQSVSGLMR 652
WP_013300173 612 PELERYRGAEISVKARTGGIDWSVGRSKGIGR------- 643
WP_013301516 610 VPASHRNAVWLGREVTLNRTGNSFQWQIGKSRSVSR--- 645
WP_013479933 616 VVERAKDFALVPWRPVLDKHIGQEVSGLMREGGINWTIG 654
WP_069707830 634 EKSHEFTLVPWRPVLEKQMGQQAGGIMRAAGISWQFGRG 672
WP_066962680 609 ERSRDFTLVPWRDVLKRNMGKAASGIMRADGISWRFGRG 647
WP_121047036 609 ERARDFTLVPWRDVLERHVGKNVSGVMRESGINWTFGRQ 647
WP_121052446 612 ERARDFTLVPWRDMLERHVGKSVGGIVRESGISWTIGRQ 650
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