Conserved Protein Domain Family
DUF4331

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pfam14224: DUF4331 
Domain of unknown function (DUF4331)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 223 and 526 amino acids in length. There is a conserved FPY sequence motif.
Statistics
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PSSM-Id: 433787
Aligned: 40 rows
Threshold Bit Score: 218.789
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013688415          21 SSHREAPLIAND-PLADNTDVYAFKS--PD---DPNSITIIANYIPTEFRNGGPNYYSFGENIRYEIHVDNDAT------ 88  Fluviic...
PRJNA234054:Hsw_3568  35 SSHREAPLIADD-PLADNTDLYAFRD--PN---NAEMINIIANYIPLELPQGGPNYNTFGENVRYEIHVKNSGA------ 102
CAN97449              33 SSHREAPAIARD-PAADNTDLYAWVE--------GGNLVILASYIPLEEPSSGPNFHGFSDDVLYEVHIARGPS------ 97 
Q01WG1                18 ASHRNGPLLLED-QTANLNDFYAFRSyeAG---KSDRLVMSMSAQGFQVPDNGPSYYKFSTSVLYRFNINNSRG------ 87  Candida...
CAN92530              24 SDHIDGPRSMGD-PAADLNDLYAFQS--PE---RADHTVLIASVFPFAGDS-----AFFSDAVNYIIAMRRVHVagsgne 92 
jgi:Cylst_0471        43 SDHQDTTFLATKlTAADLTDLYFFES--PT----SDNIVLVMDFDPLIVSGET---RPFDPNVLYQFKIDNTGD------ 107
jgi:Npun_AR247        69 SDHQDTTFLATKlTAADLTDLFVFES--PT---NPKNVVLVMDFDPLIVSGEK---RPFDPNVLYQFKIDNTGD------ 134
WP_012628962          37 SDHDDGEYPEKG-RNRNITDLYVFREvdQNksaNPGDLVFVFNTNPRSLPRQQ---YYFDPNARYEINLTRVADlns--- 109 Cyanoth...
WP_015205384          63 SDHDDGETDTKG-RNLNLTDLFVFRAqdQNpnaPTGNLVFIMNTNPRSMPRQP---YYFSNRARYEFKVKRVADknaspt 138 Crinali...
WP_012163044          43 SDHDDGETNTKS-RNLNLTDLYVFREgdQNpnaSTDDLVLIMNTNPRSVARQQ---YYFNNKARYEFHIARTPDnda--- 115 Acaryoc...
WP_013688415          89 ---TPg-DD-ITYRFTFSKINQD-------------PTTFFAVr-LG--------QENAKTTYMI-------EKS----- 129 Fluviic...
PRJNA234054:Hsw_3568 103 ---NAnqDD-ITYRFTFRRVNED-------------ATTFFNIr-LG--------KQNLKATYTL-------EVS----- 144
CAN97449              98 ---SL--EDaLTYQFRFSTRPYVaadpagltpapsgGNEFFSQlagG------------EQTYTV-------TKI----- 148
Q01WG1                88 ---LDgaPD-MQIDFQFRDTYRD-------------NPTFVsy--fGkissidspGIFLYETYEViirdlkqNKIvavyd 148 Candida...
CAN92530              93 arfQAakEE-LNFTCRFGPLEASt-------------------------------------------------------- 115
jgi:Cylst_0471       108 ---NV--ED-LVIQFNVNGTGPG-------------------------------------QNVTV--------------- 129
jgi:Npun_AR247       135 ---SI--ED-VVLQFNVNGKGSQ-------------------------------------QTVTV--------------- 156
WP_012628962         110 rptGQ--KD-VTLRFTFAPPSSN--------------------------------QQFGQQNLTL-------TVIdrg-- 145 Cyanoth...
WP_015205384         139 tayAN--PD-VILRFEFSEPTGS--------------------------------NPFKQQQILL-------TVIrd--- 173 Crinali...
WP_012163044         116 tptGK--PD-VTLRFEFSQP-----------------------------------KPNQTQTVKI-------TTIrdgss 150 Acaryoc...
WP_013688415         130 -TDGGAt--FTTFMTGLAVPPPNIGERSIgnapvglgaAN-YDA-LIASSIYATp-----EGGQVFCGPSDDPFFVDLGG 199 Fluviic...
PRJNA234054:Hsw_3568 145 -RNGGA---FTAIVNGGIVPPPNIGPRSIqgaa-glgaPS-YES-LMTGAIQTV------GNVKVFCGPVDDPFFTDLGG 211
CAN97449             149 -----EggaSTVLLRDAPVAPPNIGRRTNqlayritggG--YPA-FATSSKFLKqm--agGAGRAWAGPRDDGFYADLGR 218
Q01WG1               149 kDVNGHp---------LSVAPPNLGPNST---------PS-YEKnLGAPSVFTLa-----NGMRVFAGPRDDAFYFDSGA 204 Candida...
CAN92530             116 -SGGKPrqrGACTLPGGGTLPLVVGDARGaat--------------------------pgGAFRMFAGLRSDPFFsgwgp 168
jgi:Cylst_0471       130 ---------------RGPSSPIKVGTESAl-------vPVtGGGaLNQAFTTTN-------GLNVFVGVRKDPFFFDLER 180
jgi:Npun_AR247       157 ---------------RGPYRPTTVGTESAl-------lPVtWTGqLNQTFSASN-------GMKFFVGTRKDPFFFDLEQ 207
WP_012628962         146 -----------ttVGRGQGVTT----------------PL-----DKARQPRLNqltiggNPVTVFAGLREDPFFFDVEQ 193 Cyanoth...
WP_015205384         174 --------gQIVANKVNAGTTT----------------P------VNTNTANVTpvavagSTLSVFAGLREDPFFFDVEQ 223 Crinali...
WP_012163044         151 hV--------------GKAITT----------------P------LNSD-PKTTqvpmggQTLFVFAGLREDPFFFDVEQ 193 Acaryoc...
WP_013688415         200 IFDLGDAPrqn---------------nggVVRDGLAKFNTHSIAIKIPVTVLQKDGlgvSSAANIldp---nyVIGVWAS 261 Fluviic...
PRJNA234054:Hsw_3568 212 IFDLGGIRt-------------------aAARDGLAKKNTHTIALQIPISELQKDGktgAQAANIlds---dyVIGVWAS 269
CAN97449             219 ASDLAGLCpllaa-----------pnpscTPRDNLAGFNVHTLALEIPLAAV-------NGGAEPtpgpsdrqTLGVWAS 280
Q01WG1               205 TFDTLNfrtpapvlsgs--adtgqgaaapAAVDGFAGYNISLIAVEMPITMVTANGaapSSATDPn------gTIGAWAS 276 Candida...
CAN92530             169 pp---------------------rnalpkAVPNALQDNNVLSIVIELDTTKVLEPRkg--------------sLFGVIAE 213
jgi:Cylst_0471       181 FFQILPdrnysfqpnpaapfqvlsfrpagEAQDTLASFNVHSIIVELPRFMLGNG------------------KIGAWIT 242
jgi:Npun_AR247       208 FFKIIPdrnyslqpnpsppftvltfrppgQAKDTLAPFNVHSIIVELPRKLLGSG------------------KIGAWMT 269
WP_012628962         194 YFRVragvlgfgp--------avgfrpasEALDFAKGYNVNAIAVRVPRKLLQG-StsvT-------------TFDSWLT 251 Cyanoth...
WP_015205384         224 FFRVraglagfgd--------kvgfrspqTAIDDFKDVNVNAIAMTVPISVLQG-SssaT-------------TFDVWET 281 Crinali...
WP_012163044         194 FFRVragalgkgp--------avgfrdpdKAVDFTTGYNVNAIAVRVPIKFLQN-QsgaT-------------TFDVWQT 251 Acaryoc...
WP_013688415         262 ASRQTTRTL-TAGSQGYAGNWVQVSRLGMPLTNE-AV---IPVGKKDFWNSLTPYQElaeTTLDEHFYNPELalymdds- 335 Fluviic...
PRJNA234054:Hsw_3568 270 ASRPAMRTLnTDGTQTHSGNWVQVSRIGMPLTNE-VI---QPIGAKDAWNAATPYTEa--ATTEDYMSNPELglymaega 343
CAN97449             281 ASRRKVRILrANGKEDGLGPWVQVSRVGLPLINT-WI---IGLQDKDKYNRAHPRDDl--ANFGAYFLNPILvrd----- 349
Q01WG1               277 TLRQIVTVrpSPNDPVNYGDWIQVDRVGNPLTVE-AL---IPLPLKDRWNRSLPVDD---QQWAPYIGDPFFa------- 342 Candida...
CAN92530             214 TTPGAARRGft-------sdVPRIDRIGRPEVTNlHMfvdGEIDLRDLWNQEDP-------------------------- 260
jgi:Cylst_0471       243 TSVKTPRLTng--------nFAQIERLAVPALNE-LF---MDFKAHNNSNLQTPIKD----------------------- 287
jgi:Npun_AR247       270 TSVKTPRLRkd--------hFAQIERLAVPALNE-LF---MDFKAHNNSNLQTPTQD----------------------- 314
WP_012628962         252 ISVRTGSG----------GQFRQVERLARPAINEgLI---VTNDFLNAFNSIPPSSDl---------------------- 296 Cyanoth...
WP_015205384         282 ISHDSSGS----------GAFTQVERLARPAVNEgLI---VSNDYLNALNMVGPDFE----------------------- 325 Crinali...
WP_012163044         252 ISVRGKG-----------GKYRQVERLARPAVNEgLI---VSNDFLNALNSVGPDFE----------------------- 294 Acaryoc...
WP_013688415         336 -iyggavPAFAGLriqrnslqgfdfgn--tqdglwplkgtaaVAgtaldd--avfgtlLLPAAGK-P------------- 396 Fluviic...
PRJNA234054:Hsw_3568 344 gyfgtavPGLGQLriqrnslgafdfangkdgvsallnapaadVAgtafakiaaggyaeYLLRPAK-P------------- 409
CAN97449             350 ----aefAGLYQA---------------------------------------------GQPLAAFdPeal---------- 370
Q01WG1               343 -------TGILKG-----------------------------VF--------------NLPVPPA-P------------- 358 Candida...
CAN92530             261 ----------------------------------------------------------FAVDPKRlPlyrdrlllsldlw 282
jgi:Cylst_0471       288 -------------------------------------------------------------APN---------------- 290
jgi:Npun_AR247       315 -------------------------------------------------------------ASN---------------- 317
WP_012628962         297 ---------------------------------------------------------sPAAAPvlaeaaktl-------- 311 Cyanoth...
WP_015205384         326 -------AAALGNvapqtasapapapapapvqpspvvsaprsVGgifrg----qrapaPAPAPAPaPapapaqptgglna 394 Crinali...
WP_012163044         295 -------AAALAgqk----------------------------------------paaKVAGPivneaaqtl-------- 319 Acaryoc...
WP_013688415         397 -------------------------RSvDLWPIFHTGVpnlapyq-latgkngNPLASGKpfisNFLPn----------g 440 Fluviic...
PRJNA234054:Hsw_3568 410 -------------------------RSvDILPIFHTGVpnvrpyqlatgkpagNPLAAGKpfinNFLPlidnpaaaagvg 464
CAN97449             371 ----------------------kqsRT-DLIDAF------------------------------NLNPaslggh-sletv 396
Q01WG1               359 -------------------------RK-DLLGVFV--------------------------------------------- 367 Candida...
CAN92530             283 ------------drrdgkvdwteagRR-ALVNVLL--------------------------------------------- 304
jgi:Cylst_0471       291 -------------------------QS-QFIKAFVTAIgrp------------------------------------sgi 308
jgi:Npun_AR247       318 -------------------------QS-QFIQAFVKAIgrp------------------------------------qgi 335
WP_012628962         312 -----------------kalgnntqEInTLVTALI--------------------------------------------- 329 Cyanoth...
WP_015205384         395 sqralaneilaeanrtllalgndqtRAtALTRAFL--------------------------------------------- 429 Crinali...
WP_012163044         320 -----------------kaignddqRTnTLLQAFL--------------------------------------------- 337 Acaryoc...
WP_013688415         441 GDMLRLNMAVPA-TPRnsAAFSSMGlvnaaVLGLtdpaynttttiqfipNMDGFP-NGRRL-------EDDVTRIELQ-A 510 Fluviic...
PRJNA234054:Hsw_3568 465 GDMLRLNMAVPA-TPRnsADFSSEGllyaaVLGLtdarfnttttlqaipNMDGFP-NGRRL-------EDDVTRIELQ-A 534
CAN97449             397 GDVLRIDLGMPS----------------------------------------GFP-NGRALvpgadheQTDVTDALLTlV 435
Q01WG1               368 PDLTRVNLFTTP-TAF--ASQNRLG-----PLGG---------------DNAGWPfGGRRP-------VDDVVDIGFR-A 416 Candida...
CAN92530             305 DDFLLIDVTKPT-TDEshREIEHSTiegrkYATG----------------------GGRTL-------DANVMNIFISyE 354
jgi:Cylst_0471       309 ADAV-ISVAIPDvIQA--DVFQTKGsyfgtQLGG---------------NF-----GGRRL-------QDDVIDVTAS-V 357
jgi:Npun_AR247       336 ADAV-ISVAIPDvIQA--DLSKPSGsyfgtQLGN---------------NF-----GGRRP-------KDDVIDVTAS-V 384
WP_012628962         330 PDVMRIDTTQPS------------Gy-----VKGv--------------NALNAPvRGRML-------KDDVIDATLN-L 370 Cyanoth...
WP_015205384         430 PDVMRIDTSQAS------------NydvtiPASCl--------------NTMGSPiCGRKL-------KDDVIDLTLK-V 475 Crinali...
WP_012163044         338 PDVMRIDTTDTS------------Gy-----GNAl--------------NSKGSPiRGRLL-------KDDVVDITLS-V 378 Acaryoc...
WP_013688415         511 VGGVVLAaiglwyddynasssaqspvtnyLLNVLNYSTGVEQN---D------VAFKTSFPYVASP 567 Fluviicola taffensis
PRJNA234054:Hsw_3568 535 VGGVVLAaiglpy-----------ettngLTNVLAFRTGIEAN---D------TTFRSTFPYAQTP 580
CAN97449             436 LTGAL---------------------------GATAGDGVGAN---D------ARFLPAFPYLATA 465
Q01WG1               417 LAGVLVPg---------------------fTNAPPLGDGVNSN---D------VPLLDHFPFHAPP 452 Candidatus Solibacter...
CAN92530             355 VNR---------------------------GRGPMLHGGAKGAt---------QPGGKTFPYVQPP 384
jgi:Cylst_0471       358 VFGDAVTg-----------------------iAVNTYPGLTT----DnvgpnnANFLPVFPYLGNP 396
jgi:Npun_AR247       385 VFGDAVTg-----------------------iSTGIIPGLTS----DnvgpnnANFLPTFPYLGNP 423
WP_012628962         371 VTKGAVK-----------------------------SDNVSYSgpgGnpaqghDPLVRNFPYLALP 407 Cyanothece sp. PCC 7425
WP_015205384         476 LTNNPAA-----------------------------TDNVSYNgtpGnpaqghKELVPSFPYLAPP 512 Crinalium epipsammum
WP_012163044         379 LTNGAIT-----------------------------TDNVSYEgtpGnpsqghSPLQTQFPYLALP 415 Acaryochloris marina
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