5KIA


Conserved Protein Domain Family
Tdh

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COG1063: Tdh 
Threonine dehydrogenase or related Zn-dependent dehydrogenase [Amino acid transport and metabolism, General function prediction only]
Threonine dehydrogenase or related Zn-dependent dehydrogenase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Statistics
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PSSM-Id: 440683
Aligned: 770 rows
Threshold Bit Score: 167.237
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5KIA_A         9 MK--AL--AKleR--G--PG-LTLTRVKKPE-VGHNDVLIKIRRTAIC-GTDIHIWK----WddwAQKT-IPVPMHVGHE 72 
WP_071141057   1 MR--AL--MR--L--SpkANdMELVNTEEPKiLKSTDVKVKVVYAGVCgGTDIKLKKvdvgG---RFDK-LKPPVILGHE 68 
NP_866632     57 SA--AV--VN--Y--ApePGsVEIREIDRPE-IGSQDVLLEVSHVGVC-GSDLHQWT----A---HHSWpVNYPVVLGHE 119
WP_003643576   1 ME--AV--VK--TesG--YDnMELKQIPIPE-VTGDKVLLKVAYTGIC-GTDIHTFK----G---QYAN-AVTPLVLGHE 62 
WP_012944977   1 MK--AI--VH--T--G--PRaIEIREREKAV-PDDDEVLVRVHSAGLC-GSDAHAYKye-dG----YEW-IPIPRTMGHE 62 
WP_071139371   1 MK--AL--VR--RtsK--ERdMILKDMPEPI-VSDNTVKIKIKYSSIC-ASDIKYYNqv-mG---PGAK-IIPPVIIGHE 65 
NP_310512      1 MK--AL--AR--F--GkaFGgYKMIDVPQPI-CGPEDVVIEIKAAAIC-GADMKHYNvd-sG---S----DEFNSIRGHE 62 
WP_012945534   1 MRglAK--TS--R--S--QGaMELIERDRPE-PEPDEALIEVDYAGLC-GSDAGIYEf--eS---AFER-MELPTVIGHE 64 
WP_041544892   1 MQ--GItkLS--N--E--SGeMDLIEFPRPI-AGHGNVVLEVAAAGIC-GTDIHILK----G---EYK--VVPPVIVGHE 61 
WP_072695073   1 MK--AL--VK--TepG--YDhMEFKEVEEPE-VYEDIVKIKTAFTGIC-GSDIHTFK----G---EYKN-PTTPITLGHE 62 
5KIA_A        73 YVGEIVEMGQEVRGFSIGDRVSGEGH-I-T-CGFCRNCRAGRRHLCRNTVGVGV--NR-EGAFAEYLAIPAF-------N 139
WP_071141057  69 ASGYAVEVGTDVKKTKIGDRVVYETT-VeP-CGSCRYCHSGDWNMCSHRKGLGS--ST-NGSFADFVVVPER-------N 136
NP_866632    120 FGGHIVQLGSDVEGWKEGDRVVSETA-AiI-DSNNPMSRRGLYNLDPTRKGFGY--GV-NGAMTRYVRVPSR-------I 187
WP_003643576  63 FSGEVVEVGPDVKTLKPGDRVTSETT-FaT-DGTCVYCQDKEYNLCPNRVGIGT--KA-NGSMANYVLTREE-------S 130
WP_012944977  63 YSGEVVEVGDDVTDFAVGDHVVEEPI-H-D-CGSCFQCKNGQPNVCQNFEITGM--HN-DGAYTEYTTVRPR-------D 129
WP_071139371  66 GSGIIVETGSKIKDYKVGDEVCFETT-FeK-CGKCMFCKSKEYNICDNRKGLGS--KV-NGTFAEYVIVPEE-------S 133
NP_310512     63 FAGCIAQVGEKVKDWKVGQRVVSDNSgH-V-CGVCPACEQGDFLCCTEKVNLGLdnNTwGGGFSKYCLVPGEilkihrhA 140
WP_012945534  65 YSGRVVEVGDAVTKFAVGDRVVERPI-R-G-CGDCYQCEIGESNVCQDAVITGV--DH-DGAYEPYIAVPED-------A 131
WP_041544892  62 VCGFVCDAGEGVDPALVGKRVVTETF-Y-SvCHTCAYCRNGRPNMCANRKSIGT--HA-NGAMTRWVEVPSH-------G 129
WP_072695073  63 FSGVVVEVGPDVKSIKVGDRVTSETT-FqT-CGECRYCKEKDYNLCSNRKGIGT--QQ-NGSFTKYLISREE-------S 130
5KIA_A       140 AFKIPPEISDDLAAIFDPFGNATH-TA--LSFNL-VGEDVLITGAGPIGVMAVAIAKHVGAR-NVVIT-DIN---DYRLD 210
WP_071141057 137 IRVIPSELSLKTAVLSEPMACAYH-IVs-ERGCIkAGENVVIIGPGIIGLCCALVALFSGAN-VVVIGtEKSr--ETRLK 211
NP_866632    188 LHEVPHSLAFEHACLTEPCCVAYN-AVv-RNARIePGDRVIVMGPGTIGILCAAMARLCGA--EVALV-GLEs-dRHRLN 261
WP_003643576 131 AHILPDNVSYKMAAMSEPLASCVH-AMy-QKTPFtLHDTLLIMGPGPMGLLSLQIAKEIGAF-VIVSGiTKD---ADRLQ 204
WP_012944977 130 LHLIPDGVPLGHASITEPLSIATR-AVf-DQSAVtPGDTVLVEGPGPIGVLVAAVADSMGA--NVFVS-GLGkdtAYRLP 204
WP_071139371 134 LHKLPDGVNLKTATLMEPLACAVH-LIe-EQIKVkKGDNVLIIGPGAIGFFSSLVAKSLGGK-VILSGtNHS---AHRLK 207
NP_310512    141 LWEIPDGVDYEDAAVLDPICNAYK-SIa-QQSKFlPGQDVVVIGTGPLGLFSVQMARIMGAV-NIVVV-GLQedvAVRFP 216
WP_012945534 132 LHPVPDSVEQQHAAMVEPTSIATR-AVi-QNSRVrAGTRVLVEGPGPIGLLTAQVARAQGG--EVVVS-GVGqdaEYRLP 206
WP_041544892 130 LHAVPDFMSDAAASMAEPVAFVTN-SMagEYNYVgPDNEVLVIGPGAIGLIAAQVARAAGANvNIRGT-TKD---KARLD 204
WP_072695073 131 VHVLPENVSLEAGAFTEPLACCTHaAL--EKTNIeATDIVLVVGPGPIGLLLSQVVKSKGAT-VILSGvTRD---ASRLE 204
5KIA_A       211 LARR-MGATrAVNVSRES--LRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPA--QT-AIDWNQV 284
WP_071141057 212 IAKK-FGCHvLVN-DGHN--LKERVQEIFDGEFADLAIDAVGSQNSFNSGLSLVRKMGRVVITGVPSLdtELyTIDMSYI 287
NP_866632    262 IAEEnYGCQ-GIVGDPTD--WANQ----RDGLGCDGVIDAAGSSVTLEIAMQVVRPAGWISKVGWGPQp--L-GYNLDPL 331
WP_003643576 205 IAKE-LGADiIVDTQKED--LAKVVMDATDGVGVTKVYDCSGATPAVNSALPLIRKGGTFQQVGLFAKp-MN-ELDERSI 279
WP_012944977 205 LVEE-LGIEt-IDIETND--LSKVVDERTDGVGFDAVFDTTGHSSGIEMAIDHVRKGGQVVVVGLPGS--PS-EVFMTPV 277
WP_071139371 208 LASE-LGIEt-ISGGEGE--VKKRVFEMTNNIGADVTVDCVGSEHTLKMAVNLARKNGIIGLGSFPKG--EI-PFNFEIV 280
NP_310512    217 VAKE-LGATaVVNGSTED--VVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFK--PL-DFSINDI 290
WP_012945534 207 LAEE-LGFEt-LNIADDD--LDAVRDELTDGVGYDVVFDTTGHPSGLPSAVDEVRKGGQIVLIGQTGE---T-TMPYSPL 278
WP_041544892 205 LAER-LGFSvS-D---NDtpL---V-----PQSFDRVVECSGSPYGIADALAALTKGGHLMQMGIVGR--DS-QLPFDYV 268
WP_072695073 205 LAKN-LGIDyTIDSLTEN--LDELVLKLTDGYGADKVFDCSGAVPAVNQALALTAKKGDFIQVGLFPDk-YI-KLDVESI 279
5KIA_A       285 IFKGLEIKGIYGREMfETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLSGesG--KVILDWA 349
WP_071141057 288 YRNQICITSGRSSTP-SSWTGSLKVLQKYhNQLEELVSHVYSPEKWKEAFEATEKK--QaiKAVIDFE 352
NP_866632    332 VQKNVTLQGSFSHNW-PIWERVLALLTSGqLNVAPIIGGIWPIDQWQTAFDKMHRG--EvvKSVLQPI 396
WP_003643576 280 IQHEITYRGSRSQNP-YDWAIALHLESKGaINQDAMITKVFDLEHWRDAFDAMMAG--KelKVMIASN 344
WP_012944977 278 VRGEVDVNTSYGSTW-RNFEQAIRLLSAGaIDADAIIDRSFSVDEPTAAFEAFLES--EtcKPVFSFA 342
WP_071139371 281 FRRQLTLIGSQSSKP-SSWIRALELMKENhHIIERMITDSFTLDDWEEAFKLVENK--SgfKVVFKMN 345
NP_310512    291 TAWNKSIIGHMAYDS-TSWRNAIRLLASGaIKVKPMITHRIGLSQWREGFDAMVDK--TaiKVIMTYD 355
WP_012945534 279 VRSEIDLQCSYASKY-EDFENALRLIDTGdVDAETFIDDRFSLLDADEAFETFVGG--GtcKPVFDVS 343
WP_041544892 269 CYKELKITAGFASTP-KSWLRAMKLIRDRkVDLEPLVSDVCALHAWKTAFDRSMSA--EgvKFVFDPR 333
WP_072695073 280 IQREINYVGSRSQKP-SSWPLALELISNGsVQVEKMVTMTEELENWRRAFEAVMEG--NevKVLLKS- 343
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