Conserved Protein Domain Family
AKNA

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pfam12443: AKNA 
AT-hook-containing transcription factor
This domain family is found in eukaryotes, and is approximately 110 amino acids in length. This family contains a transcription factor which regulates the expression of the costimulatory molecules on lymphocytes.
Statistics
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PSSM-Id: 463585
Aligned: 20 rows
Threshold Bit Score: 32.4306
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_008271618  592 FQRLQAAHRA-LEEEYLKASRAQHLARQLAGSEGTPGKFDPGRELEMKIYHLGTRLEELKDLVNQTQQAPEPSGCDSapd 670 
XP_023400780  523 FQWLKAAHTA-LEEEYLRACKDQHLTQQPASSEGMPGKFDPERELEAEIFQLGIRLEELKDHVDQHQQKPEPVGSDS--- 598 
PNI69567      219 CGQVGSPPEAdGPGSATSGAEKATTRRKAPST---PSP----------------------------KQRSKQAGSSP--- 264 
XP_008262994  342 SPGPKMKPPVpIRQELLPGVESETTLFKLTST-SQKDHLLNSSYIFLKISQGKQMCQSLKEQTEQLKSKVQEFSKSI--- 417 
XP_023359198  322 YLQVNGEPLLdVSERAFSGLASETNVLKLSSS-TKEQLPSSPSQLLTK----AERCQELSEQTKNLKTKVEEFSKRI--- 393 
XP_011238451  322 SQQIQVQPAThTCQEPLTGLEPEKCCLNLTPT-PQKDPFSN-SYIFQKISHGKQMCQKLKEQTDQLKNKVQEFSKRI--- 396 
XP_012355927  327 SQQIQMEPTVhIHQELLTGIESEASLSKLSPT-SQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRI--- 402 
XP_023612786  321 SQQTEMKPAThSHQEHLTGTGSETRLWKLSST-SQKDPSLSSS-IFQKISQGREMCQKLKEHTDQLKTKVQEFSRSL--- 395 
ELW70615      599 FQWLKAAHAA-LEEEYLKACRGQHHAQQLSGSRGPPGKFDPSRELEAEIYHLGIRLEELKDRIDQTQQEPASSRSDS--- 674 
XP_023366334  624 FQQLKDAHAA-LEEEYLKASREQYLAQQPTSSKGTPGEFDPSRELEAEIYHLGICLEELKDHMNQTQQESEPSRSDP--- 699 
XP_008271618  671 iAPDIapamPSSRQPRHLPTPPGQ 694 
XP_023400780  599 -AVDSppptPSPSHPTGLPSPSQQ 621 
PNI69567      265 -RPP-----PGLWYLATAPPAPAP 282 
XP_008262994  418 -KQDS----DGHLQDGRLEDRSGP 436 
XP_023359198  394 -SQD-----FTPLEDNKQVLEELQ 411 
XP_011238451  397 -KQDS----FCHLQDIRLMNKEHA 415 
XP_012355927  403 -KQDS----PYHLQDKKLVLEKLQ 421 
XP_023612786  396 -AQDS----PGYEQDERLELQKLQ 414 
ELW70615      675 -ALAHstaaPFPHQPAYLPAPSGQ 697 
XP_023366334  700 -ALDSslatPLSHQPTHLPAPSEQ 722 
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