Conserved Protein Domain Family
CysG2

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COG1648: CysG2 
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme transport and metabolism]
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) is part of the Pathway/BioSystem: Heme biosynthesis
Statistics
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PSSM-Id: 441254
Aligned: 605 rows
Threshold Bit Score: 73.6467
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_019400986  29 LS-VVPVFLDLAGKCAVVAGGGDAAAWKAELLVAAgAEVHVYAPreELSGEFSRLLERfqakwtpvrrpetrqnekierv 107
WP_011499298   8 RK-YLPLFIDMEGRKVVVFGGGSVGFRKASLFAEY-AETVVISI--DLSPELEELASS---------------------- 61 
WP_013037897   4 RR-YMPLFLDLSSQKVVIFGAGNVGQRKASLFYKF-AEVTIISE--EFSEDILAMYES---------------------- 57 
WP_012036262   1 MSdYLPLYIDFKGRRIVIFGGGGVGERKARYFSGV-ADVTVVSP--AFTPALEAM------------------------- 52 
WP_013719201  10 RP-LLPLFLDMSQRLVVIFGGGKVAERKALLFSDY-GPVQVVSQ--SFTPKL--LASK---------------------- 61 
WP_005579887   1 ---MLPLFHDFEGRSVVVVGGGSVALRKTRYFAPE-ADVTVVAP--EFVDGFENLEC----------------------- 51 
WP_048147141   5 NC-FLPLLIDMSGRKIVIFGGGSVSERKALLFSRY-ADVTVISK--GFTPCIRQLHEE---------------------- 58 
WP_020449548   1 ---MLPLYLDLKSKKVTVFGGGAVGYRKASYFGEE-ADVTVVSK--EFVDDFSN-------------------------- 48 
WP_070365656   1 ---MIPLFHDFSDRRVVIFGGGTVAARKAALFATE-AEVVVPSL--AFHERFSEIDCR---------------------- 52 
WP_119821438   1 ---MLPLFHDFEGKTVVIVGGGRVALRKARTYTIE-ADVTVVAD--AFADGFDEVDCE---------------------- 52 
WP_019400986 108 cvsqesghalftadlpGRLVHHDAHWD---AAA-----FS----GATVAIAEAEEDAEAAAFRAASLGAGVPCNVIDKPa 175
WP_011499298  62 ----------------SKVELIKSDLSsvsDESil-dlME----DAFLVIPATNVPSLNDRIRELAQGCGILVNRIDM-- 118
WP_013037897  58 ----------------NKIDIVQINIReisSDMir-nyLD----GAFLAIPATSDRDLNLKIHLIASDMDIFVNSVDS-- 114
WP_012036262  53 ----------------GGITRIQKAAA---REEig-elIS----GAFLVIAATGDEEFNSAVVREAQSAGILVNSAHG-- 106
WP_013719201  62 ----------------DRWELTECDLRv----Dfk-ryLQ----GAFIAIPATSNSQLNRSIEEEAIRVGILVNRVEG-- 114
WP_005579887  52 -------------------TLQQRALA---PGEag-dvVD----GVALVVPATDDRELNDAITDAAREAGCLVNRVDE-- 102
WP_048147141  59 ----------------NKIKIVEADISdltNEQad-ifLD----GAFLVIPATNDRSVNERLVSAAKTKNILSNPVDF-- 115
WP_020449548  49 ----------------SSYELVNADIF-----EvadewIE----KSDFVVAAA-DPCVNDFVSKRSEVAGKPYNRSDSP- 101
WP_070365656  53 ----------------LHR----TQID---GDLaa-wyAD----DAFLVIPATDDAELNDRIAARAAEQGALVNRVDE-- 102
WP_119821438  53 ----------------RRR----RRLE---PDEad-elLAsvegDLFLVIPATDDRTLNDAIARAGREAGALVNRVDE-- 106
WP_019400986 176 FCSFQFGTIVNRSPLVVGISTSGAAPVLGQAVRRRIEALLPAWLADWAGLAADMRERVMARLG-PGARRRAFWEAFVDRA 254
WP_011499298 119 AGEVVIPSVIQRNGLSIGISTFGSSPAVSKYTRRKLEAIITPQYGEMIRLQDEMRTLLKSKVD-LQKERKALLWKILEDK 197
WP_013037897 115 RGDVIVPSVIKRGPVTIGISTLGHSPALSKYTRIKLEHTITPEYGKMAYLQDELRTELKKHIA-DQSLRRQILWKVLDRR 193
WP_012036262 107 ESGVILPSRITKGDISVAIATGGKSPAMSKYLRQRLEAALGEEMADMVRLQADVREVLKKVVP-EQKDRERLLWDILKTP 185
WP_013719201 115 RGEVVVPSIIRKGQISIAIST--ESPGLTRYLRLRLEEELTEDYQGMAKLLGRLRPELKELIP-GQEDRARAIRNILEDK 191
WP_005579887 103 PGDTVTPSRVESAQVTVAISTHGASPATTKYLRQRIEAEL-ERADPMVALQSELRDALRSAVAfPPAKRRDALWRVLEDE 181
WP_048147141 116 IGDVTVPSVIKRGDLTISISTSGSSPAFSRFARQRIEEVITPQFEDMIRIQESLRTYLKEKVP-EQNGRKDILWQVLKSR 194
WP_020449548 102 -GSFLIPSLVKRDNFSVAISTYGNSPAMSRYLKVWLDQYLDEKYDKMIEFQRQLRDELKKTIP-NQKEREKILREVLEDP 179
WP_070365656 103 AGRTITPSVIAGDNLTVGIATGGGSPAVSKYLRQQLEAEF-ETLDPMVELQSELRER---AEDlPSAARREFLWDVLEDD 178
WP_119821438 107 RGDTVTPARAESGTLTVAISTGGESPAVARHLRREIEPLL-ERTEPMGRLQADLREQLAEESDlSADQRRQALRRVIDDD 185
WP_019400986 255 -FRAAPGGDAA---GALEADAGRIAR 276
WP_011499298 198 aIWDALEVS-YekgYNVAYNIVQEHL 222
WP_013037897 194 eIWDAFEES-YekaYNIAYDIMLEQI 218
WP_012036262 186 aVWEAMKTS-YddaLTLALMMIEERR 210
WP_013719201 192 eVWRLLGHS-YekaYMRARSHACQDE 216
WP_005579887 182 tVWECLEAGREadaRTRAWEIVDDLE 207
WP_048147141 195 eVWEGLEVS-YekgYNVALGIVTEKI 219
WP_020449548 180 tAWTAGSFGie--------tvIsahi 197
WP_070365656 179 rIHETLEAGKFeqaRTLAMEHHP--- 201
WP_119821438 186 gVWRALEDGRYedaRDRALEVAGIDP 211
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