Conserved Protein Domain Family
ycfN_thiK

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TIGR02721: ycfN_thiK 
thiamine kinase
Members of this family are the ycfN gene product of Escherichia coli, now identified as the salvage enzyme thiamine kinase (thiK), and additional proteobacterial homologs taken to be orthologs with equivalent function. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]
Statistics
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PSSM-Id: 274268
Aligned: 8 rows
Threshold Bit Score: 343.997
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAM85341        34 HISPVSGLTGESWRIT-GPGIDWLAREQSPHKSQLgVNRRRERKFLQHIAGNgLSPAVIAANQRWLVVNWLEGDVVTneq 112 Yersinia pest...
P75948          25 VTTFNSGLSGGSFLIE-HQGQRFVVRQPHDPDAPQ-SAFLRQYRALSQLPAC-IAPKPHLYLRDWMVVDYLPGAVKT--- 98  Escherichia c...
Q8ZQ07          25 AVATSQGLSGGSCIIA-HDTHRVVLRRHHDPDAPP-AHFLRHYRALSQLPAS-LAPRALFYTPGWMAVEYLHGVVNS--- 98  Salmonella en...
CAE15197        26 KIRPLSGLTNESYYAT-NGEYHIVGRRQGQQGKQLgVNRQRENAILRHLSQVkIAPQVIAMVPHWLLLEWLPGHIIGqne 104 Photorhabdus ...
CAG74716        16 HFELIGGLSSQSWRIR-GPGIEWLARRQSPVERKMgVDRQREFALLRQMSAVgLAPRPLLWRDGWLIVEWVPGRIATsde 94  Pectobacteriu...
BAC59231        30 VQTVTGGLTNRCWRLEsSQGLAYVWRPTSNVCKAFsISRHNEYQVLHAIEPLnLGPKPIFVHEQGLLVEWIDGITLTkd- 108 Vibrio paraha...
CMCP6:VV1_2071  30 VQTVTGGLTNRCWKINdHAGKSYVWRPASKVCQAFsISRYSEYQILNAIADLkLGPKPVLVNEHGVLVEWLEGETMRdg- 108 Vibrio vulnif...
vfiat:VF1141    15 VSALSGGLTNACLKVEaKEG-SFVWRPISLQAKILgADRAKEHEILQALSDEsFSPNVYGENEEGILVEWLEGEVIAldk 93  Vibrio fische...
AAM85341       113 --fiPLVNHGQLARLLARLHHLPASGYRLDLRAQIARYGALIDPTRRSPGGVRLQHDFLRRPLPAITKIAPLHMDIHPGN 190 Yersinia pest...
P75948          99 ----YLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGN 174 Escherichia c...
Q8ZQ07          99 ----ALPDADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDN 174 Salmonella en...
CAE15197       105 --fsQPDLLQKLAALLAILHHQPLFGYRLQLRHQLESHWLQIDKARLTPCWLRLHKRFMSSPMPSILKLSPAHMDVHYGN 182 Photorhabdus ...
CAG74716        95 --flMMLANGEVARVLSQLHRQPRSGHPLNFKILFAQHWQLMDPCRRSPALLRAHHHFQRAALPTPLALVPLHLDVHAEN 172 Pectobacteriu...
BAC59231       109 --giELEELLPIAATIHQYHSSSIPVVPFSYISRIDHYWLELEGKYVGSEFETLYKQWRSEPSVEQIPLALCHFDLGCYN 186 Vibrio paraha...
CMCP6:VV1_2071 109 ---vAPDTLLKTAIKIHQFDAHTLPLAPFSYTARVDHYWMQLEGKYLGSEYENLYQQWRSAPSVTPLPVALCHFDLGGYN 185 Vibrio vulnif...
vfiat:VF1141    94 aqdvAVDLLCSVHQISLDKLSEQIKNKPMSLKDRIIDYWNSITPENQTPEMEAYFEYFSQQDEQAFFSHCLCHYDIGAYN 173 Vibrio fische...
AAM85341       191 LLTTPVGLKLIDWEYAADGDIALEIAALFRGnhwSMLQQQAFLQDYCNNEHGYHdiARLSRQIQQWLPWVDYLMLMWFEV 270 Yersinia pest...
P75948         175 LVHSASGLKLIDWEYAGDGDIALELAAVWVE---NTEQHRQLVNDYATRAKIYP--AQLWRQVRRWFPWLLMLKAGWFEY 249 Escherichia c...
Q8ZQ07         175 IVLTSAGLRLIDWEYAGDGDIALELAAVWVE---DERQHRQLADAYAARARIDA--RQLWRQIRLWHPWVIMLKAGWFEY 249 Salmonella en...
CAE15197       183 LLNTSQGLKLIDWEYATDTDIGFALAALFRTnhwDEPQQQDFLNYYCSQSSGYSnrTLLERQIKRWLPWVDYMILMWFEV 262 Photorhabdus ...
CAG74716       173 LLITPQGTMLIDWEYASDGDIAFELAFIVRAsqmDSVAQTYFLQSYQRHRRGFSv-SRLQQQMMQWFPWVDYLVLMWFEV 251 Pectobacteriu...
BAC59231       187 LVRGDQGVKVIDWEYASLADPRLDLTLILQIt---DSPIEESVERYCQIRNIENt-SVWLEGVKAWQPRTLVMAMLWYLL 262 Vibrio paraha...
CMCP6:VV1_2071 186 MVKGPDGVKVIDWEYAALADPRLDLTLTIQLs---GEDWFEMVCRYCQLREIDEv-EVWIEGVKAWQPRTTMMAMLWYLL 261 Vibrio vulnif...
vfiat:VF1141   174 IVVKEDGYGLIDWEYASMGDPSQDLTSMIIAn---QFDMDDVISLYCQKRRLNi--DEWKRAVIHWTPWVTFMGALWFSL 248 Vibrio fische...
AAM85341       271 RWQQTADPIFLAWAAPLRQRFN 292 Yersinia pestis KIM10+
P75948         250 RWRQTGDQQFIRLADDTWRQLL 271 Escherichia coli K-12
Q8ZQ07         250 RWRQTGEQQFIRLADETWRQLR 271 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
CAE15197       263 RWKQSGDPQFLELAQPLRLSFG 284 Photorhabdus luminescens subsp. laumondii TTO1
CAG74716       252 RWQQTKNLEFLAEIPALRHRLQ 273 Pectobacterium atrosepticum SCRI1043
BAC59231       263 AYKLWGDEQYLNSAQEFKDLLC 284 Vibrio parahaemolyticus RIMD 2210633
CMCP6:VV1_2071 262 AHKIWGDDEYLLTAKQMLHSLC 283 Vibrio vulnificus CMCP6
vfiat:VF1141   249 GYQLLKNTCYQELAEREMCKLI 270 Vibrio fischeri ES114
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