Conserved Protein Domain Family
gag_pre-integrs

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pfam13976: gag_pre-integrs 
GAG-pre-integrase domain
This domain is found associated with retroviral insertion elements and lies just upstream of the integrase region on the polyproteins.
Statistics
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PSSM-Id: 372857
Aligned: 1083 rows
Threshold Bit Score: 31.9525
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EED21271      543 RLYLIEW-D-ENRK--PRSS------LgndlalssfERKvlKDPGNVWHKRLGHISEQAVEKLQEategalvtsPRA--- 609 
XP_002556819  532 GLYHLDA-T-QLPS--DNMTrgviaaT---------VDF--DDPVWKWHRRLGHLGFQNMLNLLR---------SSTgme 587 
EDS32970       32 KLYCMDF-DlKHQRsdRAMV------T---------GQV--EQQVGLWHLRYGHLGNDNLLKLAK---------KNI--- 81  
Q9LS18        427 TLYMLKG-K-AVTA--RRRA------V---------QGP--KEETKMEHIKPAHMSQTSLEIPVK---------KGC--- 473  thale cress
Q8TFK0        195 NNKYIKI-S-NMNH--EIAN------P---------FKR--KRDLMYYHLMGNHMSLESMKYLIK---------SGH--- 241  Debaryomyces ...
CAR65566      531 NNKYIKI-S-NMNH--EIAN------P---------FKR--KRDLMYYHLMGNHMSLESMKYLIK---------SGH--- 577 
XP_002770212  531 NNKYIKI-S-NMNH--EIAN------P---------FKR--KRDLMYYHLMGNHMSLESMKYLIK---------SGH--- 577 
XP_001544588  469 GVYALDLwT-SLTF--PAYH------V--------------SPQMKLWHNRLAHMSDTNLRHLKR---------Q-A--- 512 
EDN11149      481 GVYALDL----WAS--LTFP------A---------YHV--SPQMKLWHNRLAHMSDTNLRRLKR---------Q-A--- 524 
ACZ04926      456 GLYKLVK-S-SCDE--VN--------V---------AVE--TLTVDALHRRLGHISSVAARKLVT---------SGL--- 500 
EED21271      610 LGRNEE------GF----KE----KCEICELSSA 629 
XP_002556819  588 ITEKQI------KAk--lKA----VCPVCATTRA 609 
EDS32970       82 VSGMQI------DDagheRL----LCKACISESS 105 
Q9LS18        474 IRKQKI------GE----VK----VCEDRAQKEV 493  thale cress
Q8TFK0        242 IKMSSEitaseeER----VK----SCNECLAINS 267  Debaryomyces hansenii var. hansenii
CAR65566      578 IKMSSEitaseeER----VK----SCNECLAINS 603 
XP_002770212  578 IKMSSEitaseeER----VK----SCNECLAINS 603 
XP_001544588  513 YGVRDV------EP----RQ----PCNPCLQGRM 532 
EDN11149      525 YGVRDV------EP----RQ----PCNPCLQGRM 544 
ACZ04926      501 VSGLKL------SG----DEsnsiTCDSCSYAKA 524 
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