Conserved Protein Domain Family
GIY-YIG_unchar_1
?
cd10446: GIY-YIG_unchar_1 
GIY-YIG domain of uncharacterized hypothetical protein found in bacteria
The family includes a group of uncharacterized bacterial hypothetical proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.
Links
?
Statistics
?
PSSM-Id: 198393
Aligned: 32 rows
Threshold Bit Score: 107.318
Created: 5-Aug-2010
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
 
putative activeputative metalGIY-YIG
Feature 1:putative active site [active site]
Evidence:
  • Comment:Based on the structure evidence that the putative active sites are well conserved in GIY-YIG homing endonuclease I-TevI (1LN0).
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                  #          # #               #   #                                   
CBK76336     44 WLDALRNQKAVYLITDtsNGKMYVGSATAqy----gMLLQRWTNYIDnGHGGNVELKHIvdtkgfdyikaNFQYSVLENY 119 Clostridium cf. ...
ACL67276    180 WVRRLSSVAGVYCILHanTGELYVGSASGk-----eGIWGRWRVYADtAHGGNVRLRARcenva--gyedDLVFSILQVL 252 Anaeromyxobacter...
ABQ67939    182 WAEALRAAQGIYLLTSdrTGEWYVGSATSsd----gGFLARWLAYAAdGHGGNIGLKSSep--------sDYQVSILEVV 249 Sphingomonas wit...
ZP_07972896 174 WQEVLKEYKGVYLIVDeeDGSQYVGSATGd-----nGFFGRWRDYHN-GHGGNESLKHRaks------aaSYYVAILQAI 241 Synechococcus sp...
ZP_05844642 197 WAARLAEWRGVYLIVDqtDGARYVGSAYGa-----eNLLGRWRAHVAgDRGVTVELARRdp--------aAFRFSILQRL 263 Rhodobacter sp. SW2
ABF92081    190 WQIPLSQWRGIYFIHDerRRLGYVGSAAGa-----eNLLGRWLDYATsGHGGNKLLRQSrp--------aDLRFSVLERT 256 Myxococcus xanth...
ZP_04093539 180 WHESLSIVAGVYLIVDtkTGKQYVGSAYNt-----eGIWGRWKTYVNnGHGGNKLLMEIlkqdp--drvnDFTYTILQVL 252 Bacillus thuring...
ZP_08160177 184 HYKALSQVKGVYLIIDttDGRQYIGSAYGe-----kGIFGRWSEYVNtHHGGNAEFIKLlknep--eryrKFRFTILKIF 256 Ruminococcus alb...
ZP_08158019 181 WHVALKSVNAIYLIVDteTGKQYVGSAYGe-----dGLFGRWCCYVNsHHGHNKKMKELicnyp--eryhAFQFSILQIL 253 Ruminococcus alb...
ZP_04254494  58 WCKMLSSVAGIYVILNkkTGKLYVGKANApggigkgGIWGRWESYAKtGHGGNKQLIELlennp--ehkqDFLFSILRTL 135 Bacillus cereus ...

Feature 1                     #               #  
CBK76336    120 narm--ddnYILSREKWWKDTLc-TRQFGYNKN 149 Clostridium cf. saccharolyticum K10
ACL67276    253 pigs--skdEVIAAETCMKEKLg-ARAFGLCAN 282 Anaeromyxobacter dehalogenans 2CP-1
ABQ67939    250 gsat--tlkDTLAIEALWKRKLqsREMGSLQRN 280 Sphingomonas wittichii RW1
ZP_07972896 242 apgnanegsLITELETYWKIKLg-SRVHGLNLN 273 Synechococcus sp. CB0101
ZP_05844642 264 dpdl--apdQVIGVEQNWKRRLd-TVSHGLNRA 293 Rhodobacter sp. SW2
ABF92081    257 spdi--avrEVVLLEQTWKRRLhtRTPCGLNEN 287 Myxococcus xanthus DK 1622
ZP_04093539 253 pnty--kdtEVFKVESLYKRKLg-SRAFGLNSN 282 Bacillus thuringiensis IBL 4222
ZP_08160177 257 sega--tvkEVLDAEDLYKAKLg-STEFGLNDN 286 Ruminococcus albus 8
ZP_08158019 254 pkti--ipeEAVRIENKWKSRLl-SMKFGMNDN 283 Ruminococcus albus 8
ZP_04254494 136 pkti--tndEILDIENIYKEKLg-TREFGYNAN 165 Bacillus cereus 95/8201

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap