Conserved Protein Domain Family
2A0309

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TIGR00912: 2A0309 
spore germination protein (amino acid permease)
This model describes spore germination protein GerKB and paralogs from Bacillus subtilis, Clostridium tetani, and other known or predicted endospore-forming members of the Firmicutes (low-GC Gram positive bacteria). Members show some similarity to amino acid permeases. [Transport and binding proteins, Amino acids, peptides and amines]
Statistics
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PSSM-Id: 273333
Aligned: 11 rows
Threshold Bit Score: 204.441
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAO36593       8 EVISNKQIQLLIFSYCIG----AYLLFSMGAGIKQDIWISSILAIIFTIPIVIMYGKIMN--LYPGKNFFDILEEVFGRM 81  Clostridium tet...
AAK76763       6 GMISSKQLSLIMLSLIEAs---TFTAVFVSQYTKQDTWVVLISGFIIVLFLLFMYVSLCS--KFPGKTIIEIHAKIYGNL 80  Clostridium ace...
P07869         8 LKLNTFQGISIVANTMLGagllTLPRALTTKANTPDGWITLILEGFIFIFFIYLNTLIQK--KHQYPSLFEYLKEGLGKW 85  Bacillus subtil...
AAS39712       9 EEIGSREIGFAVSSTIIGigalSMPRDIANQTLFSDGWIILLLGGLICAVLGWFVTRVAI--LFPKQNFVQYTSAHLTKP 86  Bacillus cereus...
AAM25678       6 DKISSNQVAILLFTTMVGag-iLSLPADVSKEVGPNGLLAILGGGLASLFFARLILWISS--KFPTETFSEYASKLVTKP 82  Caldanaerobacte...
CAC17461       7 NALSTSQTIVMIAGSMIGig-iLSLPANLSKIAHNDGWIGMIIGSLYPFYMTLCAILIFKdnSYQNTNIVEISKNYFGKI 85  Clostridium bot...
AAP10508       7 REISLFQYILTISGVQVGfg-vLTLPREVAQGANTDGWMSIIIGCALTTLVSLCIVKIME--KHPEYTLLDVLTRYLGKW 83  Bacillus cereus...
AAO36915       2 DNINAKHLFFIISAITIVs--lKTYPTIFIRNAGRDSWIVVIIASLIILFSFIFMLKTSL--KTNTFDFYNIYTSSFGKI 77  Clostridium tet...
Q9ZFB5         1 MVNFFQIALVLIGSTGIInh-vIIIPMLLDHSGRDSWISIIILSLVYIIWIPCVFIVHKY--TREEHLFSWLMRNYGGFI 77  Bacillus anthracis
WP_010898095   5 TTISTYQFFSMIVLFELGs----AIVVGVGLDAGQDAWMTVLIAMLAGLVLYCVLYYLHS--HFPSDTWIAYLQKVLTVP 78  Bacillus halodu...
WP_003243872   2 DKTSAYQGLFFGALYTLAvg-lKHAPILMIESAKQNAWHSYILGVVIVIPALWLMHRLMK--KHQDKNIYELLSDSS-PI 77  Bacillus subtilis
AAO36593      82 VGKVLNIIFIFHAFFLGAYILRDFADFIKVTALFSTPMIVPMICIGILSIWILTEGIEVLAAWAKFLIRI-ILISMILIW 160 Clostridium tet...
AAK76763      81 LVNLISLLYIFYFWFIIPANFRFLADFFSTYLSQNSDIIPFIIPAAILCIYAVRKGAEVISRVSSILSIL-TVMLSIIIT 159 Clostridium ace...
P07869        86 IGSIIGLLICGYFLGVASFETRAMAEMVKFFLLERTPIQVIILTFICCGIYLMVGGLSDVSRLFPFYLTV-TIII-LLIV 163 Bacillus subtil...
AAS39712      87 VAYTISMVLVLTFAALTAYESRMIAIISQTYLFSETPVQLLSFFFLLVVIYGIAGSRAALLRLNVMFLPI-VLIA-IVLL 164 Bacillus cereus...
AAM25678      83 VAVVLSIVLIFYLSVFVSLDVRIFGEVLKIYLLPSTPIETIIITMLFASAYLVRYGLEPIARMSEILFPI-MVIP-LLLL 160 Caldanaerobacte...
CAC17461      86 LGSLLSFIFTLQFFAYIVITTANISNMLRVYLVLFLEQYKLAIPILLISVYTASKGIRTLGRINEVIFYA-SIPL--IVL 162 Clostridium bot...
AAP10508      84 LGRVGMIFWILYAVLAAISLIFSLLYVIHIWILPRTPMFLIMILLSIPMLMLACKGVLIISRYAVFTVFF-TLWMp--FL 160 Bacillus cereus...
AAO36915      78 LGTILHFFFVFSLFLTLIECAGIESSSMHANILLDTPTWYIAIFIVFTAIYPVKKGHLSVLAVTIIGIIL-MILAg-INL 155 Clostridium tet...
Q9ZFB5        78 TYPLLSIIVLYLIILGTVTLKETLTFFSFYLPE-TPRILLGVLLSIICFYNIQRGVQSIALTTGILLPVV-FLLGf-FVM 154 Bacillus anthracis
WP_010898095  79 IGWFIGFLYCLYFIYIATRVLRDFGDLLTTSMLTDTPLMVINLLMVFVIVYVLFHGINVLARTGEFFLIIlFFIGFFSVT 158 Bacillus halodu...
WP_003243872  78 AGRIIILLFSLYFLLINAHDIRFFINLINILFLPRTPMAVLGGVIIFVAICIAREGKETLTRMAQIFLFP-FGIL-VLFL 155 Bacillus subtilis
AAO36593     161 IMLIPEMH-ISNLQPVFYADLKDILKQAL-HL-ITFPFSEVIIFLNFFDYVNYNSKTKNVFIKPLILGgMLVVLYTMINL 237 Clostridium tet...
AAK76763     160 ALIAKDIH-ISNLLPPLQLNLGQFVQGTN-IM-VAIPLGEIIVFMIFFPHLNDQTKLRKSAFTGLILS-FIFFLFVLVRN 235 Clostridium ace...
P07869       164 FGISFKIFdINNLRPVLGEGLGPIANSLT--V-VSISFLGMEVMLFLPEHMKKKKYTFRYASLGFLIPiILYILTYIIVV 240 Bacillus subtil...
AAS39712     165 SLLNINLMeINNLFPAFQTEVSQYAVGVKnSI-FTFIGFEVALFYAVLLNDKTAKKAPMAVAKAVIVNvLSYILIYVTCI 243 Bacillus cereus...
AAM25678     161 FLPALSDVdLTNFLPFMRVSLMKFLKGVF--V-TTYSFVGFELLYMVFPYVIDQEKLKKSVNASIISTtLFYMYICFFVI 237 Caldanaerobacte...
CAC17461     163 TAMAIKQGnIINIQPILGNPFSSILKASI--E-PVYAFVGIEIIFLIVPLMKDKNKIKSSFLKSTSIIvFLYIWLSFVSI 239 Clostridium bot...
AAP10508     161 LFIPLKDGhWIYLLPLLKEGWIPVLNTVK--S-TIIAFLGFEFAFVLYPYLSNKSSAKKGIVLANLITlFIYLQVTFVSF 237 Bacillus cereus...
AAO36915     156 AILTSSYKkYKYLFPILENGLNKNHFLAL-LK-VLGLYAHIVIFFPYLELVHNKNKIFKVSIWSFIFViQMQIIAIVGIL 233 Clostridium tet...
Q9ZFB5       155 IANFPHKDySLLKPIMEHGMDPVIKGMIYp---AAGFVELIFILFLQHHIGSKIKLSQLIIVGIILAG-ITLGPTIAAIV 230 Bacillus anthracis
WP_010898095 159 LIFSTDLYnIKNLMPVLENGWMPVLREAF-PVtFTFPFGEIIVFTMLFHFLNKKEMGLRIGLLAIGMSgLLLALTTILYI 237 Bacillus halodu...
WP_003243872 156 PFTLATQIeLQNLTPVFE-GLIPYLQSGY------YAFGTMGELIILPLLFSNRSVPLKYTIFAILLGaLLLAVMLFSSI 228 Bacillus subtilis
AAO36593     238 MLLGGELYSFFYYPGYESIKRLNLG-NEFQRLEIIVSIAFTIIQFLEINFCILGVSKGITKVFNLKEYRRVLIPVIIllI 316 Clostridium tet...
AAK76763     236 TLVLGNVSSLQVQPAYQVSSLINVG-EVITRVEVTTAVFLLFNLLMKICFFLYATVISIAQCFKLRSYKPLVFPVTAisA 314 Clostridium ace...
P07869       241 GALTAPEVKTLIWPTISLFQSFELKgIFIERFESFLLVVWIIQFFTTFVIYGYFAANGLKKTFGLSTKTSMVIIGi---T 317 Bacillus subtil...
AAS39712     244 SVFTYMTTRGLTYPTIELGKEIEIGgGFLERFDAIFFTTWIITIYNTTAMYYDVASLLFCAMFPKVKKHIFIFGSAP--L 321 Bacillus cereus...
AAM25678     238 GIFGYKETKEQLWPFLTLIKSINFPvFFIENVEGIVMAIWTFTIFTSIYSFHYFAVLVLSKLIKAREHSYLVLPLIP--P 315 Caldanaerobacte...
CAC17461     240 YYLGADVAKNLYWPTLSLAETISIP--GISNFKFVFMFLWSSIIFKTIANQNYFFYYSLSSILKKINPSILYVIVFL--F 315 Clostridium bot...
AAP10508     238 VYFSPDGITKFLWPTLSLVTPFHFS--FLERFEIIFLSFYLFIIFDSCIPYIFTASDGINQFLNKKGSSLPIYVLLFg-C 314 Bacillus cereus...
AAO36915     234 STFEINHAKNLIYPKLLQTQLISYWr-FIESGEFFVMLQTVGGWYVKYVLVLNILNKSFEKIFTGNKYLIYIVSILT--- 309 Clostridium tet...
Q9ZFB5       231 EFGPFVAANQRYPTFEEWRLVSIGK-YIEHLDFLSVYQWLVGVFIRISLVIFLIPDVLQVTKQKARNQIISILLICM--V 307 Bacillus anthracis
WP_010898095 238 IVLGVDITNRATFPLLTMVGKIQAA-DFIERLDALAVTVLVVAMFFKVAIFFYAGVAGFSELFKVDKFQKLLPLFGAilV 316 Bacillus halodu...
WP_003243872 229 SVFGPNLTSTFFDPAYMVIRQIRIT-DFLDRSDLIIAAFWIPVIMVKIAGSLYIVVYGLSFLHSKIDPKAMYTPTGMfsV 307 Bacillus subtilis
AAO36593     317 TFDYVMFGSAMEAFEIVRELWPAYG-IVIQIVLPFIIFIFATIKRKNQL 364 Clostridium tetani E88
AAK76763     315 VLSITMFKSPLDQLYIASDIYPIYA-LLFIVILPITSFILASIKKSSKT 362 Clostridium acetobutylicum ATCC 824
P07869       318 VFYFSLWPDDANQVMMYSDYLGYIF--VSLFLLPFILFFIVALKRRITT 364 Bacillus subtilis subsp. subtilis str. 168
AAS39712     322 IFMLNMLPGNLNTLSSYGTYLAWID-MGFVVLAPLLVFIVYKIKRRNGR 369 Bacillus cereus ATCC 10987
AAM25678     316 MYLMALIPDSIVTLYKYANLVSQYLsIFFISFLPIILAFFVKLKGLGDK 364 Caldanaerobacter subterraneus subsp. tengconge...
CAC17461     316 ATTIVIKLDSFILLQKINKGVSIFY-LIFNLIFITTITIIKIIKNGGKN 363 Clostridium botulinum
AAP10508     315 IFILFFYIPSSYQISALREFWGTAS-YFIVFLFPVVFLLYMTLYQHWKR 362 Bacillus cereus ATCC 14579
AAO36915     310 YIFTSFLTQKLLRFFDFLNFYSLIS-FINFLLIPFIAFIILYFKNNKSI 357 Clostridium tetani E88
Q9ZFB5       308 IICILPISDASFYWFLSHVFLPISA-IGLFLFSMLLLVFVWVSKNKKRA 355 Bacillus anthracis
WP_010898095 317 FNSVHIAANFSEHLKEGLEVVPYYLhLPFQVGIPLIVLAIVLIRkkmgs 365 Bacillus halodurans
WP_003243872 308 VCGFWFFLN-TNQLIDFNRIKPIIN-VVISLLLPLLIYLIIKSKALFGA 354 Bacillus subtilis
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