2OT9,2G3W,3C0U


Conserved Protein Domain Family
YaeQ-like
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cd22368: YaeQ-like 
Nucleases similar to Escherichia coli YaeQ
This model characterizes a diverse set of poorly characterized nucleases such as Escherichia coli YaeQ. They belong to a superfamily of nucleases including very short patch repair (Vsr) endonucleases, archaeal Holliday junction resolvases, MutH methyl-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and FokI.
Links
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Statistics
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PSSM-Id: 411772
Aligned: 16 rows
Threshold Bit Score: 250.708
Created: 23-Jan-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved Features/SitesClick to see Conserved Features Help
 
putative active
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
  • Structure:2OT9: Pseudomonas syringae YaeQ protein active site binds tartrate; contacts at 4A
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                          #                            #              # 
2OT9_A         5 STTYKFELNLTDLDRGVYESVKQTIARHPSETEERXTVRLLAYAFWYNEQLAFGRGLSDVDEPALWEKSLDDRVLHWIEV 84  Pseudomonas syr...
3C0U_A         7 ATIYKATVNVADLDRNQFLDASLTLARHPSETQERXXLRLLAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIEL 86  Escherichia col...
WP_009849200   5 STIFKAELQITDMDRNYYQDHQLTMARHPSENDERMMVRLLAFALNASESLQFTRGLSSEDEPEIWQKSMSDEIELWIDL 84  Mariprofundus f...
PHS62027       5 ATIFKAELNVSDMDRHHYQTYNLTIAQHPSETTERMMVRLAAFTLNASEQLEFTKGLSTDDEPDLWAHSLSDEIDLWIEL 84  Thalassobium sp.
PRD19658       5 STIIKAQLSLSDMDRHIYQDFNLTLAQHPSETEQRLMIRLLAFALNAREGLEFTKGLCADDEPELWHINYSEEIELWVEL 84  Trichonephila c...
XP_024267118   5 ATIYKAELQIADMDRNYYQQHLLTLARHPSETDERMMIRLLAFAIHASDSLAFTKGLFDTDEPDLWQKDLTGAIQLWVEV 84  Chinook salmon
RBL81955       5 ATIYKAELNVADTDRHYYGSHSLTVARHPSETDERMMVRLVAYALHAQEELAFTKGLSDTDEPDLWVKDLTGAVKLWIEV 84  Streptomyces ca...
GFD75847       5 ATIFKADISITDMDRNYYNDHNLTIARHPSENDERMMLRIIAFIVNAHERLQFTKGLSDDDVPDLWQKSFSDEIELWIEL 84  Tenacibaculum s...
TVL97572       5 ATIFKIALNIADIDRNYFHDHKLTIARHPSENDVRMMTRLVAFVLNAHEDLVFTQGVSRGDEPDLWRKDLCGNIEMWIEI 84  Candidatus Broc...
PCK07590       5 ATIFKLNLNVSDITRHYYQSHALTIARHPSENDERMMMRVTAFALNACEQLSFTKGLSTNDEPDLWEKSLSDEIEHWIEV 84  Alteromonadacea...

Feature 1        #                                                                               
2OT9_A        85 GQPDADRLTWCSRRTERTSLLAY--GSLRVWEGKVIPAIKNlKNVNIAAVp---qDVLEVLAKdxprVIKWDVXISEGTV 159 Pseudomonas syr...
3C0U_A        87 GLPDERRIKKACTQAAEVALFTYnsRAAQIWWQQNQSKCVQfANLSVWYLd---dEQLAKVSAfadrTXTLQATIQDGVI 163 Escherichia col...
WP_009849200  85 GQPDEKRIRKACGRAREVVIYTYqqRSSEVWWEQQRNKLERfDNLGVVNIpdesvALLGQMAQr---AMRLQCTIQDGQL 161 Mariprofundus f...
PHS62027      85 GQPDEKRIRKACNRAKQVIIYGYhgRASQLWWQQVESSCQRfNNLRVVDFd---aAAIEQLQQltgrTMRLQASIQDGML 161 Thalassobium sp.
PRD19658      85 GLPDEKRLKKACNKSKQVVLYTYgeNNQAIWWQKHQPKLYDfKNLSIFSLdy--aATQALADLad-rNIKLTITIQEGEV 161 Trichonephila c...
XP_024267118  85 GQPDEKRLMKACGRSEKVVVYSYg-ATSHIWFKQIANKLERaKNLAVINIp---sDAAVQLQKmanrNMQVQCTIQDGQI 160 Chinook salmon
RBL81955      85 GQPEERRILRACGRADEVIVYCYggSASKIWWDGVRNKLERtRNLKVVNLp---sDQTRALARlaerTMQLNANISDGVV 161 Streptomyces ca...
GFD75847      85 GQPSEQRIKKGCNQSQKMIIYSYadNSFDAWWNKEQNKLQTrKNLSVFTLp---eSLSTTLAHavqrSMQIQVTIQDGQM 161 Tenacibaculum s...
TVL97572      85 GQPDEKQIRKACGRAKEVIIYTYsgNSANAWWKKISPDVHRfKNLSVINLppesiQEMAVLAQr---TMDFPCTIQEGEV 161 Candidatus Broc...
PCK07590      85 GRPSEDKIRKACARAKRVTVYLFggNVAEQWWLANQEKLQRfGKLAVYIId---ePSSLALKElvsrKMEVQCTIDEGQA 161 Alteromonadacea...

Feature 1                          
2OT9_A       160 FVTDdrgqHEVQLQWLTG 177 Pseudomonas syringae pv. tomato str. DC3000
3C0U_A       164 WLSDdknnLEVNLTAWQQ 181 Escherichia coli K-12
WP_009849200 162 WFSNgeqaIEVMPDIWKR 179 Mariprofundus ferrooxydans
PHS62027     162 WLGDs--sQTIEIGMTVL 177 Thalassobium sp.
PRD19658     162 WVSS----DTANIEIKPQ 175 Trichonephila clavipes
XP_024267118 161 WLTDsv-dTVLVEREPFK 177 Chinook salmon
RBL81955     162 YFSAe---KGEVSIEPEA 176 Streptomyces cavourensis
GFD75847     162 WLTIe--gAEVTESVEIA 177 Tenacibaculum sp. KUL113
TVL97572     162 WLSVgd-kTVKICPIKWK 178 Candidatus Brocadia sp. WS118
PCK07590     162 WLSI----GDQNIEVCPK 175 Alteromonadaceae bacterium

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