2KUO


Conserved Protein Domain Family
zf-CCHH
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pfam10283: zf-CCHH 
PBZ domain
This domain is a zinc-finger motif that in humans is part of the APLF, aprataxin- and PNK-like forkhead association domain-containing protein. The ZnF is highly conserved both in primary sequence and in the spacing between the putative zinc coordinating residues and is configured CX5CX6HX5H. Many of the proteins containing the APLF-like ZnF are involved in DNA strand break repair and/or contain domains implicated in DNA metabolism.
Links
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Statistics
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PSSM-Id: 463043
Aligned: 68 rows
Threshold Bit Score: 33.6278
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2KUO_A        61 RPECPYGPSCYRK-NPQHKIEYRH---NT 85 
Q22W29       542 KPDCWYGVNCYTR-NPQHNKIYNH---AC 566 Tetrahymena thermophila SB210
XP_021500632  59 RPDCYWGRNCRTQvKAHHAMKFNHiceQT 87 
XP_002121818 392 KPECEYGLDCYRR-NPLHRKQFKH---TK 416
EEC00376     403 RESCKYGKKCFRK-NALHLKNFKH---PT 427
XP_004346784 376 RPVCTYHPHCYRK-NVEHLKQFAH---PP 400
EGG22548     800 KPMCKYGAACYRK-NADHLKEFNH---PK 824
EFA86269     669 KPKCKYWDTCYRT-NPQHLAEFLH---PK 693
Q54E19       869 KPKCKYGSSCYRT-NPDHLREFSH---PN 893 Dictyostelium discoideum AX4
XP_011433142 103 RPDCTYWEKCYRK-DPNHLKQFRH---PA 127
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