3QE7


Conserved Protein Domain Family
Xan_ur_permease

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pfam00860: Xan_ur_permease 
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Permease family
This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterized and may transport other substrates. Members of this family have ten predicted transmembrane helices.
Statistics
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PSSM-Id: 395690
Aligned: 20 rows
Threshold Bit Score: 231.032
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3QE7_A  15 LQTIPLSLQHLFAMFGATVLVPVLFHIN-------------P-ATVLLFNGIGTLLYLFiCKGKIPAYLGSSFAFISp-- 78  Escherichia coli K-12
P39618   1 MKLVLGALQWTAFIIAAAIVVPVAVAQSfhldh---sdsarLiQSTFFVLGIAAVIQCL-KGHRLPINESPAGLWWG--- 73  Bacillus subtilis sub...
P77328   8 RESLLSGFQWFFFIFCNTVVVPPTLLSAfqlpq---sslltLtQYAFLATALACFAQAF-CGHRRAIMEGPGGLWWGt-- 81  Escherichia coli K-12
Q60850  80 GGLSYPPAQLLASSFFSCGLSTVLQTWMgsrl-----pliqApSLEFLIPALVLTNQKLpLTTKTPGNASLSLPLCS--- 151 house mouse
O18061  19 SAIFFFGLQQMLVCISALLVTPYFVSNLlcagaettevrvqLiAATFISSGIATILQTT-FGLRLAILHGPSFAFFP--- 94  Caenorhabditis elegans
O18057  15 PSIMLFGLQQMMICLSSLLVIPYVVSDMlcagdqameirvqLiSATFVTSGIATILQTT-FGMRLSILHGPSFAFLP--- 90  Caenorhabditis elegans
P75892  30 AQTAVMGVQHAVAMFGATVLMPILMGLDp--------------NLSILMSGIGTLLFFFiTGGRVPSYLGSSAAFVG--- 92  Escherichia coli K-12
P45117  16 LKQSFVGLQMLFVAFGALVLVPLITGLDs--------------NTALLTAGVGTLLFQFcTGKQVPIFLASSFAFIApi- 80  Haemophilus influenza...
Q18771  30 GIALLYGLQQVMVCVSALLTVPLIMADSmcpgssiavlrqtLiSSTFVSSGISTIIQTL-FGMRLALLQGTAFAYVPsvq 108 Caenorhabditis elegans
O34978  12 KQEIIAGLTTFFTMVYIVVVNPVILANAgvp-------fdqVfTATIIASIVGTLWMALaANYPIAIAPGMGLNAYL--- 81  Bacillus subtilis sub...
3QE7_A  79 --vLLLLPLG------------YEVALGGFIMCGVLFCLVSFIVKKAGTG-WLDVLFPPAAMGAIVAVIGLELAGVAAGM 143 Escherichia coli K-12
P39618  74 ---VYTIYAGltgt----vfatYGDTLRGLQGALLVSAVCFFLLSVFKVIdRLAKLFTPVVTGVYLLLLVMQLSQPIIKG 146 Bacillus subtilis sub...
P77328  82 ---ILTITLGeasr-----gtpINDIATSLAVGIALSGVLTMLIGFSGLGhRLARLFTPSVMVLFMLMLGAQLTTIFFKG 153 Escherichia coli K-12
Q60850 152 ---LTRSCHGle---------lWNTSLREVSGAVVVSGLLQGTIGLLGVPgRVFPYCGPLVLAPSLVVAGLSAHKEVAQF 219 house mouse
O18061  95 ---ALHTFGDvypcnsdtdttqWKEKLQMISGSLFVAVLIMPFLGITGMVgRIAKHIGPITIVPMLMLLCIGTVQDIEQK 171 Caenorhabditis elegans
O18057  91 ---ALHTFQAtfpcdantdtsnWQEKMQMISGSCLIAVLIMPILGFTGLVgKISKYIGPVTIVPIMSLLTIGTVPDIESK 167 Caenorhabditis elegans
P75892  93 ---VVIAATGfngqg---inpnISIALGGIIACGLVYTVIGLVVMKIGTR-WIERLMPPVVTGAVVMAIGLNLAPIAVKS 165 Escherichia coli K-12
P45117  81 --qYGVQTWG------------IATTMGGLAFTGLVYFALSTLVKLRGAE-ALQRFFPPVVVGPVIIIIGMGLAPIAVDM 145 Haemophilus influenza...
Q18771 109 gfmSLPENTCnatesdyvpeevYYGKLALLQGCLIASSFVPILIGATGLVgMLTKFIGPLTVSPLMLLLAFSQVDLMVTH 188 Caenorhabditis elegans
O34978  82 ---AFHVVSAs----------dGGITYATAFSAVFTAGVLFIILSLTPLRkQLIEAIPNNLKYGITTGIGLFIAFIGLRQ 148 Bacillus subtilis sub...
3QE7_A 144 AGLLP---AEGq---tPDSKTIIISITTLAVTVLGSVL---FRGFLAIIPILIGVLVGYALSFAMGi--vDTTPI----- 207 Escherichia coli K-12
P39618 147 ILGIGy-rQDG-----VDGLVFGLALVVIAAAFIMTNS---NIMFFKQYSILLALFGGWVLFAAAG----AAKPI----- 208 Bacillus subtilis sub...
P77328 154 MLGLPfgiADPnf--kIQLPPFALSVAVMCLVLAMIIF---LPQRFARYGLLVGTITGWLLWYFCFpsshSLSG------ 222 Escherichia coli K-12
Q60850 220 CSAHWglaLLLillmvVCSQHLGSCQIPLCSWRPSSTSthiCIPVFRLLSVLAPVACVWFISAFVGtsviPLQLSe---- 295 house mouse
O18061 172 VSHHWisiVEIllliiFVVLLEEFEVPMPAFSMEKKAFytaKMKIFSQFPYLLGIMIAWFVCWILTi--tDLEPYgcsar 249 Caenorhabditis elegans
O18057 168 MALHWisiVEFltlilFVVILERYEVPIPIFSLSEKKFkftRQKIFSQFPYLLGISIVWFICFIMTi--tNAEPRggear 245 Caenorhabditis elegans
P75892 166 VSAS--------------AFDSWMAVMTVLCIGLVAVF---TRGMIQRLLILVGLIVACLLYGVMTnv-lGLGKAvdf-- 225 Escherichia coli K-12
P45117 146 SLGK-----NSa---yAYNDAVLVSMVTLLTTLSVAVF---AKGLMKLIPIMFGITAGYILCLFLGl--iNFQP------ 206 Haemophilus influenza...
Q18771 189 ISKHWvaiVQAvt--lFATILYLAEVKVPVPGIKNGKFhwyRINLFGQYPYLIAICTSWIFCVALTi--fNLTPEgsaar 264 Caenorhabditis elegans
O34978 149 AGIVAa--dESnl--vTLGNLHSPGVILTLVGLLISVV---LMVLNVSGALFIGMAATALIAFFTGq--lHFSKG----- 214 Bacillus subtilis sub...
3QE7_A 208 ---------INAHWFALPTLYTPRFEWF--------A-ILTILPAA-LVVIAEHVGHLVVTANIVKKDLLR---DPGLHR 265 Escherichia coli K-12
P39618 209 ---------EMPDRLFQLPSLFPFGTPLf------nSgLIITSIFItILLIVNMLASMKVVDIAMKKFSKQpdgKHHERH 273 Bacillus subtilis sub...
P77328 223 ---------E--LHWQWF--P--LGSGGal-----sPgIILTAVITgLVNISNTYGAIRGTDVFYPQQGAG---NTRYRR 279 Escherichia coli K-12
Q60850 296 ---------PSDAPWFWLPHPGEWEWPLl------tPrALAAGISMaLAASTSSLGCYALCGQLLRLSPPP---PHACSR 357 house mouse
O18061 250 tdrneslfvLENTPWIQIQYPLQYGLPKl------sApLIIAFSASmLAATIESIGNYGICARICQQGSPP---SSSMNR 320 Caenorhabditis elegans
O18057 246 tdqnasitvFDQTPWVQMPMPLFFGPPKf------nLaLVCGFTAScFAAMIESIGDYNLCAKISKQSRPP---PSNTNR 316 Caenorhabditis elegans
P75892 226 -------tlVSHAAWFGLP---HFSTPAf------nGqAMMLIAPVaVILVAENLGHLKAVAGMTGRNMD-----PYMGR 284 Escherichia coli K-12
P45117 207 ---------VIDAPWFSLP---KLTTPef------nLeAILYMLPIaIAPAVEHVGGIMAISSVTGKDFLK---KPGLHR 265 Haemophilus influenza...
Q18771 265 vdknislavIRESSWLEVPYPGKFGPPQf------nTgLFLLFLLSaMTSVFESVGDYHAAARVSEERPPP---SHAINR 335 Caenorhabditis elegans
O34978 215 ---------FMSLPHL--PEGLMISNPFtafgdvihHgLYAVVFSFlLVTIFDTTGTMIGVAEQAG-LMKNn-kLPNVRK 281 Bacillus subtilis sub...
3QE7_A 266 SMFANGLSTVISGFFGS-TPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPV-MGGVSLLLYG 343 Escherichia coli K-12
P39618 274 AGFAASFSHLLSGLTGA-IAPVPISGAAGFIETTKMPSKKPFMLGSILVIVISVIPFFMNTFASLPSPV-GFAVNFVVFS 351 Bacillus subtilis sub...
P77328 280 SFVATGFMTLITVPLAV-IPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPV-SSAVMLVSYL 357 Escherichia coli K-12
Q60850 358 GLSLEGLGSVLAGLLGSpLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTSIPLPV-LGGVLGVTQA 436 house mouse
O18061 321 AFVVEGFGSMLAALMGVgTGVTTYSENIAIMQVTKVTSRITMQCAGVILILMGIFSKFAAFLAMIPEAI-IGGVLTAGMS 399 Caenorhabditis elegans
O18057 317 AFVVEGIGCILAALWGVgTGVTTYAENIAIMSVTKVTSRITMQMAGVFLILAGVISKFAAFLSMIPEPI-IGGLLAMGVC 395 Caenorhabditis elegans
P75892 285 AFVGDGLATMLSGSVGG-SGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAV-IGGASIVVFG 362 Escherichia coli K-12
P45117 266 TLLGDGIATAAASLVGG-PPNTTYAEVTGAVMLTRNFNPNIMTWAAVWAIAISFCGKVGAFLSTIPTIV-MGGIMMLVFG 343 Haemophilus influenza...
Q18771 336 GILAEGLGSLISGLLGPgVGMTTHTENIGVIGVTRVASRWTMVMAGVFLIILGLITKIGALLSTIPDPL-VGGVLASSMA 414 Caenorhabditis elegans
O34978 282 ALLADSTATTVGAVFGT-SPTTAFIESSAGVAAG----GRTGLTALTVAVMFAASMFFSPLVSALSGIAaITSPALIIVG 356 Bacillus subtilis sub...
3QE7_A 344 VIGASGIRVLIESKVDynKAQNLILTSVILIIGVSGAKVNIG 385 Escherichia coli K-12
P39618 352 AMGGLAFAEFDSYEKEe-SKRVRSIIGISLLTGVGIMFVPET 392 Bacillus subtilis subsp. subtilis str. 168
P77328 358 PLLFSALVFSQQITFT---ARNIYRLALPLFVGIFLMALPPV 396 Escherichia coli K-12
Q60850 437 VVLSAGFSSFHLADID--SGRNVFIVGFSIFMALLLPRWLRE 476 house mouse
O18061 400 MICGVAFSNLQSVDLR--LSRNLTIIGLSIILGCTIPAHFEK 439 Caenorhabditis elegans
O18057 396 LINGVSLSNLQTVDMK--LSRNLTIIGVSIIMGLTVATHFEK 435 Caenorhabditis elegans
P75892 363 LIAVAGARIWVQNRVDlsQNGNLIMVAVTLVLGAGDFALTLG 404 Escherichia coli K-12
P45117 344 SIAVVGMSTLIRGKVDvtEARNLCIISVVMTFGIGNMFVDVG 385 Haemophilus influenzae Rd KW20
Q18771 415 MVVGVAVSNLQTVDMT--LSRNMGIFGFSMMFGLIVPKYFKL 454 Caenorhabditis elegans
O34978 357 SLMMGSVSNMNWKEMD--EAFPAFLVILAMPLTSSISTGIAL 396 Bacillus subtilis subsp. subtilis str. 168
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