Conserved Protein Domain Family
PRK09532

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PRK09532: PRK09532 
DNA polymerase III subunit alpha; Reviewed
Statistics
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PSSM-Id: 181933
Aligned: 16 rows
Threshold Bit Score: 1710.72
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
218440338   1 MSFVGLHIHSDYSLLDGASQLPALIDRAIELGMPAIALTDHGVMYGAIELIKICRSKN-IKPIIGNEMYVINADLDDRsK 79 
81301008    1 MSFVGLHMHSDYSLLDGASQLPDLVARAKELGMPAIALTDHGVMYGAIELLKVCKNQGnIRPIIGNEMYVINSPIDDPnP 80 
56751907    1 MSFVGLHMHSDYSLLDGASQLPDLVARAKELGMPAIALTDHGVMYGAIELLKVCKNQGnIRPIIGNEMYVINSPIDDPnP 80 
298492518   1 MSFVPLHIHSDYSLLDGASQLPELVDQAITLGMKAIALTDHGVMYGAVELIKVCRSKN-IKPIIGNEMYIINGDIEKQ-E 78 
75907825    1 MSFVPLHIHSDYSLLDGASQLPELIDQAIALGMKAIAVTDHGVMYGAIELLKICRSKN-IKPIIGNEMYILNGDLAKQeR 79 
17231070    1 MSFVPLHIHSDYSLLDGASQLPELIDQAIALGMKAIAVTDHGVMYGAIELLKICRSKN-IKPIIGNEMYILNGDLEKQeR 79 
172038990   1 MSFVGLHIHSDYSLLDGASQLNALIDRAVELEMPAIALTDHGVMYGAIELIKVCRNKG-VKPIIGNEMYVINGDIEEK-K 78 
257061441   1 MSFVGLHIHSDYSLLDGASQLNALVDRAVELEMPAIALTDHGVMYGAIELMKVCRNKG-IKPIIGNEMYVINEDIEVN-K 78 
284928809   1 MSFVGLHVHSAYSLLDGASQLDALVDRAIQLGMPAIALTDHGVMYGAIELIKVCKNKN-IKPIIGNEMYVINGDITEK-K 78 
22299599    1 MSFVGLHIHSDYSLLDGASQLPDLVARAMELGMPAIALTDHGVMYGAIELLKLCRGKP-LKPIIGNEMYVINGDITKQ-E 78 
218440338  80 KHRKYHQVVLAKNNQGYKNLVKLTTISSLHGMHGKGIFARPCINKELLKEYHEGLIVTSACLGGEVPQNILAGKLDQAKK 159
81301008   81 RVRKYHQIVLAKNKKGYQNLVKLTSISHLQGFKGRGIFARPCIDKEHLEKYREGLIVTSACLGGEIPQAILQSRPDVARR 160
56751907   81 RVRKYHPIVLAKNKKGYQNLVKLTSISHLQGFKGRGIFARPCIDKEHLEKYREGLIVTSACLGGEIPQAILQSRPDVARR 160
298492518  79 RRPKYHQVVLAKNTKGYRNLVKLTTISHLQGVQGKGIFSRPCINKNSLKEYKEGLIVTSACLGGEIPQAILSKRPDAARK 158
75907825   80 GRPKYHQVVLAKNTKGYKNLVKLTTISHLQGVQGKGIFSRPCINKDLLKEYHEGLIVTSACLGGEIPQAILSNRPDAARK 159
17231070   80 GRPKYHQVVLAKNTKGYKNLVKLTTISHLQGVQGKGIFSRPCINKDLLKEYHEGLIVTSACLGGEIPQAILSNRPDAARK 159
172038990  79 KYKKYHQVVLAKNTQGYKNLVKLTTISHLKGMQGKGIFARPCINKELLEQYHEGLIVTSACLGGEIPQRILAGDIKEAKA 158
257061441  79 RHRKYHQVVLAKNTQGYKNLVKLTTISHLKGIQGKGIFARPCINKELLTQYHEGLIVTSACLGGEVPQSILAGDTKQAKT 158
284928809  79 RYKKYHQVVLAKNTQGYKNLSKLTTISHLEGVQGKGIFSRPCINKELLEKYHDGLIVTSACLGGEIPQKILSGDFQGAKE 158
22299599   79 RKPRFHQVVLAKNKQGYHNLCKLTTISHLQGFQGKGIFARPCINKELLAQYREGLIVTSACLGGEIPQAILQGKPELARS 158
218440338 160 VAKWYKDLFGDDYYLEIQDHGSPEDRIVNLGIVKIAKDLKIKIVATNDSHFISCYDVEAHDALLCIQTGKLITEEKRMRY 239
81301008  161 VAAWYQERFGEDFYLEIQDHGSPEDRIVNVEIVRIAQELGIELVATNDSHFISCFDVEAHDALLCIQTGKLVVEDKRLRY 240
56751907  161 VAAWYQERFGEDFYLEIQDHGSPEDRIVNVEIVRIAQELGIELVATNDSHFISCFDVEAHDALLCIQTGKLVVEDKRLRY 240
298492518 159 VAKWYKEVFGEDFYLEIQDHGSQEDRIVNVEIVKIARELGIKFIATNDSHYISCFDVEAHDALLCIQTGQLISEDKRMRY 238
75907825  160 VAKWYKDVFGDDFYLEIQDHGSQEDRIVNVEIIKIARELDIKFVATNDSHYISCFDVEAHDALLCIQTGKLISEDKRMRY 239
17231070  160 VAKWYKDVFGDDFYLEIQDHGSQEDRIVNVEIIKIARELEIKFVATNDSHYISCFDVEAHDALLCIQTGKLISEDKRMRY 239
172038990 159 VAKWYKKLFKEDFYLEIQDHGSVEDRIVNVAIAKIARDLDIKIVATNDSHFISCYDVEAHDALLCIQTGKLITDEKRLRY 238
257061441 159 VAKWYQKLFKDDYYLEIQDHGSQEDRIVNRELVKIARDLGIKIIATNDSHFISCYDVEAHDALLCIQTGKLITEDKRLRY 238
284928809 159 VAQWYKKIFANDFYLEIQDHGSTEDRIVNVSISKIAQDLNIKIIATNDSHFTSCYDVEAHDALLCIQTAKLISDEKRLRY 238
22299599  159 VAAWYQQTFGEDFYLEIQDHGSQEDRVVNVELVRIGRELGIKIIATNDSHFISCHDVEAHDALLCIQTNKLLSDEKRLRY 238
218440338 240 SGTEYLKSADEMRQLFRDHLEDEMIEEAINNTLEVADKVVQDyKILGEPRIPDYPVPPGHTADSYVEEKTWEGLLERLKC 319
81301008  241 SGTEYLKSAEEMHQLFRDHLPDDVIAKAIANTLVIASKIEDY-NILGEPKIPTFPVPDGYNEETYMAEVARQGLAERLNC 319
56751907  241 SGTEYLKSAEEMHQLFRDHLPDDVIAKAIANTLVIASKIEDY-NILGEPKIPTFPVPDGYNEETYMAEVARQGLAERLNC 319
298492518 239 SGTEYLKSAQEMQQLFRDHLPDYVIAEAIATTEEVGDKIEPY-HIMDEPKIPTPPIPSGHTPDTYAEEIAWQGLLERLNR 317
75907825  240 SGTEYLKSGEEMKLLFRDHLTDDVIAEAIATTEEVADKIEPY-HIMGEPRIPNYPIPSGHTPDTYVEEVAWQGLLDKLNR 318
17231070  240 SGTEYLKSGEEMKLLFRDHLTDDVIAEAIATTEEVADKVEPY-HIMGEPRIPNYPIPSGHTPDTYVEEVAWQGLLEKLNR 318
172038990 239 SGTEYLKSADEMRLLFRDHLSDDVIEEAVNNTLEVAEKIEPYkDILGEPRIPNYPVPAGHNPDSYVEEIAWQGLLERLKC 318
257061441 239 SGTEYLKSAEEMALLFRDHLPDDVIEEAINNTLEVADKIEPYkNIFGEPRIPNYPVPSGHTPDSYVEEIAWEGLLERLKC 318
284928809 239 SGTEYLKSIDEMKLLFRDHLDDDLIKEAINNTLEVANKIDTY-HILGEPRIPDFPVPIGHDLDSYVREISLQGLLERLNC 317
22299599  239 SGTEYLKSAAEMARLFRDHLPDEVIQEALANTLEVADKIEAY-NIFREPQSPEFPVPPGHTADTYLEQVAWQGLLERFQL 317
218440338 320 RSVIEIPPAYKQRLEYELKMIQQMGFSTYFLVVWDYIKYARDHEIPVGPGRGSAAGSLVAYALKITNIDPVHHGLLFERF 399
81301008  320 DRYEDCEEAYRDRLEYEIKMMHEMGFASYFLVVWDYIKFARDNNIPVGPGRGSAAGSLVAYCMGITNIDPVHHGLLFERF 399
56751907  320 DRYEDCEEAYRDRLEYEIKMMHEMGFASYFLVVWDYIKFARDNNIPVGPGRGSAAGSLVAYCMGITNIDPVHHGLLFERF 399
298492518 318 KSRSEVDQIYKERLEYELKMLQRMGFSTYFLVVWDYIKFARDNNIPVGPGRGSAAGSLVAYAMRITNIDPVHHGLLFERF 397
75907825  319 KSRNEVEPVYRERLEYELKMLQQMGFSSYFLVVWDYIKFARDNNIPVGPGRGSAAGSLVAYTMGITNIDPVHHGLLFERF 398
17231070  319 KSRNEVEPVYRERLEYELKMLQQMGFSSYFLVVWDYIKFARDNNIPVGPGRGSAAGSLVAYTMGITNIDPVHHGLLFERF 398
172038990 319 RSRSEIPDEYRERLEYELKMLQQMGFSTYFLVVWDYIKYARDNHIPVGPGRGSAAGSLVAYCLKITNIDPVHHGLLFERF 398
257061441 319 RSRGEISDVYKERLEYELKMLQRMGFSTYFLVVWDYIKYARDNGIPVGPGRGSAAGSLVAYCLKITNIDPVHHGLLFERF 398
284928809 318 KSINQVSEEYQQRLEYELDMLEKMGFSSYFLVVWDYIKYARDNEIPVGPGRGSAAGSLVAYSLKITNIDPIYHGLLFERF 397
22299599  318 SDRQQLEATYRQRLEYELKMLQQMGFSNYFLVVWDYIKYARDHNIPVGPGRGSAAGSLVAYALRITNIDPVHHGLLFERF 397
218440338 400 LNPERKSMPDIDTDFCIERRDEMIKYVTEKYGERNVAQIITFNRLTSKAVLKDVARVLDIPYSESDKMAKLIPVSRGKPT 479
81301008  400 LNPERKSMPDIDTDFCIDQRDKVIDYVTKKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADRMAKLIPVARGKPA 479
56751907  400 LNPERKSMPDIDTDFCIDQRDKVIDYVTKKYGEDRVAQIITFNRMTSKAVLKDVARVLDIPYGEADRMAKLIPVARGKPA 479
298492518 398 LNPERKSMPDIDTDFCIEKRDQVIEYVTNKYGADRVAQIITFNRLTSKAVLKDVARVLDIPYGEADKMAKMIPVVRGKPT 477
75907825  399 LNPERKSMPDIDTDFCIEQRDKVIEYVTDKYGKERVAQIITFNRLTSKAVLKDVARVLNIPYGEADKMAKLIPVVRGKPT 478
17231070  399 LNPERKSMPDIDTDFCIEQRDKVIEYVTDKYGKERVAQIITFNRLTSKAVLKDVARVLNIPYGESDKMAKLIPVVRGKPT 478
172038990 399 LNPERKSMPDVDTDFCIERRDEMIKYVTRKYGEANVAQIITFNRMTSKAVLKDVARVLDIPYAESDKMTKMIPVSRGKPT 478
257061441 399 LNPERKSMPDVDTDFCIERRDEMIKYVTEKYGEANVAQIITFNRMTSKAVLKDVARVLDIPYSESDKMAKMIPVSRGKPT 478
284928809 398 LNPERKSMPDVDTDFCIERRDEMIKYVTKKYGEKNVAQIITFNRMTSKAVLKDVARVLDIPYSESDKMTKMIPVTRGKPT 477
22299599  398 LNPERKSMPDIDTDFCIDRREEVIQYVTQKYGSDRVAQIITFNRMTSKAVLKDVARVLDIPYSQADQMAKLIPVVRGKPV 477
218440338 480 KLKVMISDETPEPEFKQKYDSDPQVKRWVDMAIRIEGTNKTFGVHAAGVVISSQPLDEIVPLQKNNDGAVITQYFMEDLE 559
81301008  480 KLKVMISDQTPAPEFKEKYEKDARVKHWVDMALRIEGTNKTFGVHAAGVVISAVPLDEIVPLQRNNDGQVITQYYMEDIE 559
56751907  480 KLKVMISDQTPAPEFKEKYEKDARVKHWVDMALRIEGTNKTFGVHAAGVVISAVPLDEIVPLQRNNDGQVITQYYMEDIE 559
298492518 478 KLKVMVSNETPAPEFKEKYDHDAKIRHWLDMAMRIEGTNKTFGVHAAGVVISAEPLDEIVPLQRNNDGSVITQYFMEDLE 557
75907825  479 KLKVMVSDTTPEPEFKEKYDNDPRVRHWLDMAMRIEGTNKTFGVHAAGVVISADPLDEIVPLQKNNDGSVITQYFMEDLE 558
17231070  479 KLKVMISDATPEPEFKEKYDNDPRVRHWLDMAMRIEGTNKTFGVHAAGVVISADPLDEIVPLQKNNDGSVITQYFMEDLE 558
172038990 479 KLKVMVSDETPTPEFKERYENDPLVRRWVDMAIRIEGTNKTFGVHAAGVVISSEPLDQVVPLQKNNDGAVITQYYMEDLE 558
257061441 479 KLKVMISDETPCPEFKERYDNDPQVRRWLDMAIRIEGTNKTFGVHAAGVVISSEPLDEIVPLQKNNEGSVITQYFMEDLE 558
284928809 478 KLKVMVSNETPSPEFKDRYDQDPLVRRWLDMAIRIEGTNKTFGVHAAGVVISSESLDEIVPLQKNNDGAVITQYYMEDLE 557
22299599  478 KLAVMISEETPSPEFKEKYDSDPVVRRWIDMAMRIEGTNKTYGVHAAGVVIASEPLDQLVPLQRNNDGAVITQYFMEDLE 557
218440338 560 SLGLLKMDFLGLKNLTTIQKTAELVKVNKNEIIDVDELPLHERKALEIIAKGELKKLPDDVEKTHKLLERGDLEGIFQLE 639
81301008  560 ACGLLKMDFLGLRNLTMIQKAIDLVQETSGQAIDPDRLPMDD-------------------PKTYQLLAKGDLEGVFQLE 620
56751907  560 ACGLLKMDFLGLRNLTMIQKAIDLVQETSGQAIDPDRLPMDD-------------------PKTYQLLAKGDLEGVFQLE 620
298492518 558 SLGLLKMDFLGLRNLTLIQKTIDLIQETNGYKIDPDEITGQERKAQHILAKGQHSTLPKEVQKAYSLLESGDLEGVFQLE 637
75907825  559 SMGLLKMDFLGLKNLTMIQKTIDLIEEKHGFRIDPYEITSQERKAQKILAKGEYKTLPKDVQKTYELLESGELEGIFQLE 638
17231070  559 SMGLLKMDFLGLKNLTMIQKTIDLIEEKHGFRIDPYEITSQERKAQKILAKGEYKTLPKDVQKTYELLESGELEGIFQLE 638
172038990 559 SLGLLKMDFLGLRNLTTIQRTADLIKQNQGVTLDLDQLPLDERKALEIIAKGTAKKLPPDVEKTHKLLEKGDLEGIFQLE 638
257061441 559 SLGLLKMDFLGLRNLTTIQKTAELIKQNRKVELDLDQLPLEERKALQIIAKGTAKKLPEDIQKTHKLLERGDLEGIFQLE 638
284928809 558 SLGLLKMDFLGLRNLTTIQRAADLIEKNRNIKLDVEQLPTDERKALKELEQGKISKLPTDIEKTHKLLGDGELEGIFQLE 637
22299599  558 SLGLLKMDFLGLKNLTMLQKTQELIEKNHGQRIDLDALPLDD-------------------AKTYQLLAEGKLEGIFQLE 618
218440338 640 SSGMRQIVRDLKPSGIEDISSILALYRPGPLDAGLIPKFIDRKHGKEPIKYEHQLLEPILKETYAVLVYQEQIMKMAQDL 719
81301008  621 SSGMRQIVRDLKPSNLEDISSILALYRPGPLDAGLIPKFINRKHGREAIDYADQMLQPILNETYGIMVYQEQIMKIAQDM 700
56751907  621 SSGMRQIVRDLKPSNLEDISSILALYRPGPLDAGLIPKFINRKHGREAIDYADQMLQPILNETYGIMVYQEQIMKIAQDM 700
298492518 638 SSGMKQIVRDLKPSNIEDISSILALYRPGPLDAGLIPKFINRKHRREEIEYETGILEPILNETYGIMVYQEQIMKIAQDM 717
75907825  639 SSGMKQIVRDLKPSNIEDISSILALYRPGPLDAGLIPKFINRKHGRENIDYESQVLEPILNETYGIMVYQEQIMKIAQDM 718
17231070  639 SSGMKQIVRDLKPSNIEDISSILALYRPGPLDAGLIPKFINRKHGRENIDYESQLLEPILNETYGIMVYQEQIMKIAQDM 718
172038990 639 SSGMKQIVKDLKPSGIEDISSILALYRPGPLDAGLIPKFINRKHGREEIIYQHKLLEPILKETYAVLVYQEQIMKMAQDL 718
257061441 639 SSGMKQIVKDLKPSGIEDISSILALYRPGPLDAGLIPKFINRKHGQEPIKYEHRLLEPILKETYAVLVYQEQIMKMAQDL 718
284928809 638 SSGMKQIVKDLKPSGIEDISSILALYRPGPLDAGLIPKFINRKHGKEAIKYEDKLLEPILKETYAVLVYQEQIMTMAQQL 717
22299599  619 SSGMHQIVRELKPSNLEDISSVLALYRPGPLDAGLIPKFINRKHGREPIQYQHELLKPILSETYGVLCYQEQIMRMAQDL 698
218440338 720 AGYSLGEADLLRRAMGKKKISEMKKHKEIFIDGSTKNGVSQEIAENLFDQMVKFAEYCLSYETQIMTVEYGLMPIGKIVE 799
81301008  701 GGYTLGEADLLRRAMGKKKMSEMVKHQSTFVEGAKKNGVAEKVAAELFDQMVLFAEYCLAADTEVLTVEYGPIAIGKLVE 780
56751907  701 GGYTLGEADLLRRAMGKKKMSEMVKHQSTFVEGAKKNGVAEKVAAELFDQMVLFAEYCLAADTEVLTVEYGPIAIGKLVE 780
298492518 718 AGYSLGQADLLRRAMGKKKVSEMQKQEEKFIDGAMKNGVKKQVAEKLFADMLKFAEYCLSYKTEVLTVEYGLIPIGEIVE 797
75907825  719 AGYTLGQADLLRRAMGKKKVSEMQKQQEKFIDGSTKNGVKKQVAEKLFEDMLKFAEYCLSYDTEVLTVEYGFVPIGEIVD 798
17231070  719 AGYTLGQADLLRRAMGKKKVSEMQKQQEKFIDGSTKNGVKKQVAEKLFDDMLKFAEYCLSYDTEVLTVEYGFVPIGEIVE 798
172038990 719 AGYSLGEADLLRRAMGKKKIAEMTKHREIFIDGATKNGVSQAIAEDLFEQMIKFAEYCLSYDTEILTVEYGPMPIGKIVE 798
257061441 719 AGYSLGEADLLRRAMGKKKISEMEKHREKFIEGAAKNGVIKEIAENLFTQMVQFAEYCLSYDTEILTVEYGAIPIGKVVE 798
284928809 718 AGYSLGEADLLRRAMGKKKASEMEKHQKNFIDGSLNNGVSRSVAENLFQQMVKFAEYCLSYDTKVLTVEYGLLPIGRIVQ 797
22299599  699 AGYSLGQADLLRRAMGKKKKEEMEKHEALFIEGAAKNGVPSAIAQELFKQMLDFAEYCLSGETAVMTVEYGAVPIRRLVQ 778
218440338 800 EQIDCTVYTVNKNGFVYTQPIAQWHYRGEQEVFEYCLEDGSTIRATKDHKFMTTDGQMLPIDEIFEQGLELKQIHLS 876
81301008  781 ENIRCQVYCCNPDGYIYSQPIGQWHQRGEQEVIEYELSDGRIIRATADHRFMTEEGEMLSLDEIFERSLELKQIPTP 857
56751907  781 ENIRCQVYCCNPDGYIYSQPIGQWHQRGEQEVIEYELSDGRIIRATADHRFMTEEGEMLSLDEIFERSLELKQIPTP 857
298492518 798 KRIECSLFSVDENGNIYTQPIAQWHHRGVQEVYEYCLDDGTIIRATKDHKFMTTIGEMLPIDEIFERDLNLLQVNGL 874
75907825  799 KGIECSVFSIDSNGIVYTQPIAQWHHRGKQEVFEYCLEDGSIIKATKDHKFMTQDGKMLPIDEIFEQELDLLQVKGL 875
17231070  799 KGIECSVFSINNNGIVYTQPIAQWHHRGKQEVFEYCLEDGSIIKATKDHKFMTQDGKMLPIDEIFEQELDLLQVKGL 875
172038990 799 ENINCTVYTVDPNGFVYTQAIAQWHYRGEQEIFEYYLEDGATIRATKDHKFMTMEGKMLPIDEIFENNLDLKQLTL- 874
257061441 799 ENIDCTVYTVDKNGFVYTQNIAQWHLRGQQEVFEYYLDDGSILRATKDHQFMTLEGEMLPIHEIFERGLELKKIKI- 874
284928809 798 ENIKCKVYTINNQGVIYTQPIAQWHDRGKQEIFEYCLDDETVIQATKDHKFMTTDNVMMPIDQIFEEGLELKKIKL- 873
22299599  779 ERLSCHVYSLDGQGHLYTQPIAQWHFQGFRPVYEYQLEDGSTICATPDHRFMTTRGQMLPIEQIFQEGLELWQVAIA 855
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