Conserved Protein Domain Family
DUF6060

?
pfam19535: DUF6060 
Family of unknown function (DUF6060)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001035) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide), polyketide and other (Aminocoumarin). This family includes a protein from the pneumocandin B0 biosynthetic gene cluster from Glarea lozoyensis ATCC 20868 and appear to be predominantly found in fungi.
Statistics
?
PSSM-Id: 437367
Aligned: 25 rows
Threshold Bit Score: 110.975
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
OTA94680      17 AVAECDNFAFTgqglaNEGFTTTYDGTLRTSAWKNCTPEItiqdg---------arrnTCEIHNPsNVgLVVHPTINLTn 87 
XP_024741328  24 AARKCKTYTPS-----GALY-QINSQIFYASAALFCDQPGtginedfsafdsscsttnSCVIGND-AInIPVQPTLNLS- 95 
XP_008078287  18 VTAQCTNFTSTsr--sSDTYSFFTSSNDVAVETLYCNETLs----------------sPCYITPK-KYaITAPRKLNISs 78 
PYI18919      35 NGTTCAVFNWDhqpvsWDEY-----PPLRISAAVSCPNTTttttt---------nntnACEITGTgGY-STYYAVTNLT- 98 
XP_025551696  35 EETTCAVFNWDrqpvsWDQY-----PPRRITAAFSCPNTTnttn----------kntdTCEITGRgGY-GTYSAVTNIT- 97 
PYH89017      34 NTAICTVFNWDqnpayWQTY-----PPRRISAAQTCPNTTttgntt-------tsgnqTCALYPS-GY-DTYDAVTNLT- 98 
XP_001268484  27 TGGNCTIFDWDhkapyLREY-----PPMRVSGAKTCPQQNdkn------------snmTCALTAS-GD-ELFPALKNVT- 86 
XP_025486975  24 NQANCTVFNWDhneayLKTY-----PPQRVSGAETCSSNKn----------------lTCALTAA-GD-ASYTARTNLT- 79 
XP_025547040  30 TQANCTVFNWNhnaayLKTY-----APQRVSGASTCADNNnr--------------nlTCALTAA-GD-AMYSAQTNLT- 87 
RSL60231     455 FKRSCTSFEPQge-ygNKGYTIPSLKTFRTSEYINCTTELaree----------geddVCEVDRY-TMgLSLNSTVNVS- 521
OTA94680      88 ldIETQRDIFSLVernasASAVaSVNFNTTI----VMNFTSD----GTWYASVGQAGFSAFTPYIRCWEGVLSDCDdDDN 159
XP_024741328  96 ---LSSSDVYSVV-----AGAT-GLDFTAKV----NSTVDAGi---SGVCLSNNTGRVVTVQYGLNCTNGTLSSCDgNTP 159
XP_008078287  79 -cPADEESIYQLA-----AQAYsSDNFTSSEfitrNTSLTNVhvgkTLLTVEPGIGKTLAWLPFQLYSAGRLSGCA-NSS 151
PYI18919      99 --GLAAGPLTALVqktvaKKQLqTSNFSAQA---------TVysgvGRMPLAPGQSAYAAEIASSYCFTGMVARCT-GGN 166
XP_025551696  98 --GLAAGPLTALVqktvdKKQLqTSNFSAQA---------MVyegvARTPLAPGQSAYLTEIGRSYCFTGTVAGCT-EGD 165
PYH89017      99 --ALFALPFASVVessvhHSALlTDGFRSNI----TGVVA------GTANLAPGQSSYLNFTGYNYCFTGTVDNCTgTGV 166
XP_001268484  87 --GLHNGYWPSMVeaavdKASYlAPAFNDSV----IVSID------QTRILQPGQSGYLNLTALMFCYTGALSNCT-GAL 153
XP_025486975  80 --SLSATAFATVVdetvgNATL-TEEFSDST----VGAID------GTRVLRPGQSAYLNFTAYQYCYTGTVEGCT-AGV 145
XP_025547040  88 --ALSAT-FISVVdetvgNATL-SEEFSRSI----AGAID------GTRMLRPGQSAYLNFTAYRYCYTGTVDNCT-SGV 152
RSL60231     522 --VSDIQPVLDAVkkaasLDRTaKIDLNETV----VVPFKV-----SESGIPAGKAGYLAFTPIMRCWEGVLGDCSgDDE 590
OTA94680     160 L---EGRATQVCGLTWLh-ADErskpvgeqKYNGIENFVQTDLSGGPADP-PPSYESV 212
XP_024741328 160 A---EGTAIQACAPSTSrsRNDl-------VPILLFSSLNVTQDQARNITvSPIAVKS 207
XP_008078287 152 L---EGVYVLAQAPYEV--NATkstengqlNVDGRVLAGTWSATQRNITAeNETAADK 204
PYI18919     167 PpiaDNTPVRVCSPLWQyvrt------vgnVMTSSTRIVNVTREQVANLT-DPFAGQN 217
XP_025551696 166 HqvaDDTPVRVCSPLWQyvpt------vgnVIVAYSGIVNVTREQAANLT-DPFAGQN 216
PYH89017     167 A---DHTAVEACAPLWAilnk------havIMRGFSTIVNVSQAQVGSYP-DPFQGQA 214
XP_001268484 154 E---NGTGVEFCAPVWQhk----------yIISGRWQVVNISKDEVSKYP-DPYANEV 197
XP_025486975 146 T---NQTAVEACAPLYHasad------dsvVLDGFYTVVNVSQAQVGQLK-DPYENQQ 193
XP_025547040 153 E---NRTAVEACAPLYH--LIDekgeegraVMDGMLSVVNVSRGAVGQFK-DPYENQA 204
RSL60231     591 Kl--DGTLIVACGYEYD----DnhnatgerTIVGEENVVQSDSKELKAKP-QPTWEEA 641
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap