2XR1,2YCB,3AF5


Conserved Protein Domain Family
COG1782

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COG1782: COG1782 
Predicted metal-dependent RNase, contains metallo-beta-lactamase and KH domains [General function prediction only]
Statistics
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PSSM-Id: 441388
Aligned: 143 rows
Threshold Bit Score: 377.932
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2XR1_A       184 VRVTALGGCKEVGRSCFLLSTP-ESRILIDCGV-NVGSDe----NMTPYLyvpevFPLNQIDAVIVTHAHLDHQGLVPLL 257
WP_015807767   1 MKLTILGAAQQVTGSMHLLQLD-NYNIIVDCGL-DYEKEty-qnENLYFP-----FDPAAIDLVILTHAHIDHSGNLPTL 72 
WP_012789090   1 MKIAFHGAARTVTGSKHLISLTnGKRILLDCGM-FQGMGretdaMNEEFG-----FDAASVTHVILSHAHIDHSGLIPLL 74 
WP_013443902   1 MKIKFIGAAREVTGSKHLITTNeGKRILLDCGM-FQGKGletdsMNRNLM-----FDPASIDYLILSHAHIDHSGLIPYM 74 
WP_013631830   1 MKLTCWGAAKQVTGSMHLLDID-NYRILIDCGLdYEGGKdl--sHNANFP-----FNPAEIDLIILTHAHIDHSGNIPTL 72 
WP_013765928   1 MKIKFCGAAREVTGSCHLITLEdGYKILLDCGL-YQGSDknledFNSRWL-----FDPAEIDCLVLSHAHIDHAGRIPKL 74 
WP_014681980   1 MYITFHGAAQNVTGSKHLIRTEsGKQILLDCGM-FQGSGaetevMNSHFG-----FDPKDVDYLILSHAHIDHCGLIPRL 74 
WP_062542998   1 MTISFYGAAQTVTGSKHLVTLEnGKRILLDCGM-TQGMGdkteeRNRSFD-----FEPENLTCVILSHAHIDHSGLLPLL 74 
WP_066402270   1 MKLTFHGAARTVTGSKHLISLDnGTNILLDCGM-FQGMGqktddLNEHFG-----FDPKSITYLLLSHAHIDHTGLIPKL 74 
WP_076378236   1 MRIAFHGAAQTVTGSKHLITLEdGTAILLDCGM-FQGMGaqtesLNQSFG-----FDAAQVSFVILSHAHIDHSGLLPKL 74 
2XR1_A       258 FKYGYEGPVYCTPPTRDLMVLLQLDYIDVAAKEGK-------------------KIPYESGMVAKTLKHTIPLDYEEVTD 318
WP_015807767  73 VRMGFNGQILCTPPTADLTELLLLDSVNIFLSKQNkrsrsk-------rtksgpEPLYLQKHVKDTVERFVTINFNKEFQ 145
WP_012789090  75 VKRGFKGTIYCTPATKDLTEILLLDSAKIQEDDTKftnkklr-----kegkpeiTPLYTIDDAKKSINALKKVNYNTWFQ 149
WP_013443902  75 YNLGFRGSVVCTNATRDLCAIMLADSGHIQELDNKwfnkkrd-----kqglppvEPIYNQIDSEKCMELFIGVAYDRRFQ 149
WP_013631830  73 IKEGYKGQILCTPPTAELSQLLLSDAVNLFFNKKKgnpkgrrklrnrsqadlytAPLYLQKHVMDTADRMVTVAYHKQFQ 152
WP_013765928  75 VKDGFRGAIHATHATRSLSSLMLLDSAMIQEREVEyknkrrskn-hnfddiaydEPIYTSKDVHATMELFISYPYEKWFD 153
WP_014681980  75 VKEGYNGKIFCTPATVDLTKLLLLDSARIQEADINylnkkrk-----regkpllKPLYTTQDAEACFDQFVAIEYGVHNK 149
WP_062542998  75 VREGYTGPIYCTPPTLELSKLLLMDSARIQNSNgng----------------nsSPLYTEEDAEQALQQFVTVPYDEPFQ 138
WP_066402270  75 VKEGFTGKIYCTPATRDLTEILLFDSAEIQTYEVDninkrra-----kknlqpyEPLYTSNDVAATLPLFELVDYDTWFD 149
WP_076378236  75 VKEGFKGKIYCTAPTRQLASILLLDSANIQKNTAHtphgsk--------eeipsDPFYDVDDVIATLPLLEVVDYNTWTV 146
2XR1_A       319 IAPDIKLTFHNAGHILGSAISHFHIGDG--LHNVVFTGDYKYEKTRLFDPaVNKFPRVETVISEATYGNANafQPALKDA 396
WP_015807767 146 INNQVSLTFIPIGHLLGAAAVILTVHENgtIKKIAFTGDIGRKNYPLLTN-PQPLPPVDYLVCESTYGGRL--HSTDSTL 222
WP_012789090 150 VDDNVEVYFTDAGHIIGSAAVHLRITENgkTTQITFSGDIGRYNDAILRS-PDVFPQADYILMESTYGSTL--HAEAAPS 226
WP_013443902 150 INDKINVKFTNSGHMLGSAVVNLELLENgkKVHLAYTGDIGRPHNRIIHP-PTAFPQCDYLITESTYGNRL--HAEEKES 226
WP_013631830 153 IRDNISLEFIPTGHLLGAAACKLTVSDNgvQKTITFTGDIGRQNSPVLVD-PEILSQTEYLVCESTYGGKH--HSTDSTI 229
WP_013765928 154 VHPKVKVMFRDAGHILGSASVSLKIEENgkVINFGFSGDVGRPHRPILRD-PLPMPEMDYLICESTYGDRT--HEDAPAE 230
WP_014681980 150 IDRDIEVLFTDAGHIIGSAAVHLTIKDQgrTARITFSGDVGRYGAEILRS-PETFPQADYILLESTYGNSL--HEDAAPT 226
WP_062542998 139 IDEDIELLFTDTGHVLGSAAINLKLQDDgkERTLCFSGDIGRFSNRILNP-PQAFPQAEIIICESTYGNRV--HDSLENT 215
WP_066402270 150 LSEEVSFIFTNTGHLIGSAAITLKIKDEgkERIIAFSGDVGRQRSVLLPS-PVPLPQADYLILESTYGDSR--HDISFNI 226
WP_076378236 147 LQPGVELLLTDAGHLLGSAAVHLKITEDdiTQQVTFSGDIGRYRHPLLCP-PQEFPQADYIIMESTYGASL--HDPLFST 223
2XR1_A       397 EKHLQMVVKNT-IERGGIAVIPAFAVGRSQEVMIVLEESIRKGLIpEVPVYLDG-MIWEATAIHATHPEYLNNDLRKLIF 474
WP_015807767 223 EQKLIETITEScIKYPGRLIIPAFSIGRTQALAYALNKIFSNGLLpSVKIFIDSpLAGSATEIYSKYHHLLNDEARAFYE 302
WP_012789090 227 DDLLIKYIHDTcKVKKGKLIIPAFSVGRTQELLYALNRAELDGKLpKVDIFVDSpLSREATDVVRHHPETFNKTVKKLLE 306
WP_013443902 227 EEDLLKIVRETcVDNRGKLIIPSFSIGRTQEIVFVLNNLYNKGLLpKIEVFVDSpLSVNATDVFRMHTECMNVDVKEVLK 306
WP_013631830 230 EETLIKHITETcLEQPGRLIIPAFSVGRTQALVYSLNKIFSKKLLpPIPVFVDSpLANRATEVYRKYKNYVNEEAEAFYE 309
WP_013765928 231 TDHFLRIIKQTcIEKGGKLLIPAFSVGRTQEIVYILDKMANEDLLpRIPVYVDSpLAVNATTIYGSHPECFDEELSDYMA 310
WP_014681980 227 ERELLKYIRHTcVDKGGKLIIPAFSVGRTQEVLYVLNNLENLGELpPVDVFVDSpLSERTTKIIKSYPQYYNEDVGRTLQ 306
WP_062542998 216 EERLQKIVNEVcVERQGKLLIPAFSIGRTQELIYSLNYLAEEGRLpDVKVFVDSpLSVYATDIMRDNPQYFRDSMQEYIK 295
WP_066402270 227 VKTLRQWVEKTcVERGGKLVIPAFSVGRTQEILYGLNQLSLEKRLpELNYYIDSpLSLKATETIKKYTDLFNERLQQVLR 306
WP_076378236 224 TDELMKLIQDTcIRKKGKLVIPAFSLGRTQELLVYLKQLTLENRLgDIPVIVDSpLSLAATEIFTEYTNCFNERIAALAQ 303
2XR1_A       475 qKGQNPFLSECFKPVDSHEARQKIIQNPQPCVILATSGMMNGGPVMEYFKAFAEDPRNTLVFVGYQADGTIGRRIQK-GW 553
WP_015807767 303 -KNNHSFEFKELSYVNDKRESLSVSNYHEPCIIISSAGMLEGGRIQDHLYYNIQNYYCTILFIGYCAKGTLGNRLLR-GD 380
WP_012789090 307 -RDDDPFDFPGLHYISTVDESKALNFREAPCVIISASGMAEAGRVKHHIANNINDSRNTILIVGYCEPQSLGGRLMR-GA 384
WP_013443902 307 -TDDDPFGFNSLHYIKNVDESKALNDYNEPCIIISSSGMLEAGRIKHHVANNISNWRNTILMVGYCSPTSLGARIQEpGL 385
WP_013631830 310 -TYGDKFEFENLSYVKELKESKEIADHFEPCIIISSAGMLEGGRIQDHLFHNIQNIYAKILFIGYCSEGTLGHRLLR-GD 387
WP_013765928 311 -IDENPFGFNGLRYVRKTEDSKKLNYSKEACIIIASSGMANAGRIKHHLYHGINDPNNTVLIVGYAAPYTPAGQLRI-GA 388
WP_014681980 307 -YDKDPFDFLRLHFIEDVEESKALNSRKNPCIIISSSGMAEAGRVKHHIANNISDSRNTILMVGYCEPGSLAGRLLN-NQ 384
WP_062542998 296 -DDPDPFGFPQLTYITEVDDSKELNKIDEPCVIISSSGMMEAGRIQHHLKTNLPDPNSAVLITGYCEPSTLGGKLMN-GA 373
WP_066402270 307 -IDDDPFHFEGLKYVESVEDSRRLVDHQEPCVIISASGTADAGRVRHHINSIINDEKNSVLFVGYCSEQSLGGQLLT-GY 384
WP_076378236 304 -ANENPFEFPGLHWTRCVEDSIKIKGITEPAIIIAASGMADAGRIRHHIADTIQDANNTILLVGYCAPGSLGGQLLS-GA 381
2XR1_A       554 KEIPMTGkngstEMLKMNMEVQVVDGFSGHSDRRQLMEYVKRMQPRP-ERVFTEHGDEKACVDLASSVYKKlKI-ETRAL 631
WP_015807767 381 PIVRLRN-----RDLMVYATIKQTDLLSGHGDHNDLLNTVRHQSSLTlKQVFLVHGETKSIGALANALQSE-GY-AVSIP 453
WP_012789090 385 KEVSIYG-----TRYEVRADVGVIRSMSAHGDYEDLSQWLSCQDPREvKKLFLVHGEYEVQTIFRNWLLKK-GFqDIEIP 458
WP_013443902 386 RFISIFG-----EMHEINARIARIEAFSGHGDYNEMKSFLSCQNPVEiKKTFLVHGEYKVQLSYADELKKA-GFhDIEIP 459
WP_013631830 388 AFIRLKG-----KDLAVFAKIDKTDLFSGHADHQDILDYIAAIPKKP-KRIFLVHGEQSSMLALKNDLENK-DY-QVSLP 459
WP_013765928 389 KEIKLFG-----EFIAVRADVEIMDSFSAHADKLELVEFLRNQRESV-KKIFLTHGDYEVQKSFRGLLLSV-GFaDVEIP 461
WP_014681980 385 EVVRIFG-----SRFEVKAEVGKIDSLSAHGDYKDLSRFLSCQNPSKvKEVFLVHGEYEVQREFKEKLHLQ-GFnQVEIP 458
WP_062542998 374 EKVYIMG-----DEVDVKAEMMIMKEYSAHADYGDIAKFLHCQDKEKiQKIFLVHGEKSTMSQLKEDLTEL-GYqNIEIP 447
WP_066402270 385 NEVEIFG-----DPSPVKAEIGRMAGMSAHGDCDELSQFLSEQDPGKvKRLFLVHGEYTVQKEFAAKLERK-GYqNVEIP 458
WP_076378236 382 QEVVING-----QEYPVMASVKSMSSMSAHGDYENLCQFLACQEPAAvKKIFLVHGEPKVQEELQKRLQHK-GFmQVHIP 455
2XR1_A       632 TNLETVRL 639
WP_015807767 454 QKGQSFEL 461
WP_012789090 459 ERHSEVGL 466
WP_013443902 460 EAGQEFTL 467
WP_013631830 460 EKGMVFEL 467
WP_013765928 462 ALGEEIDL 469
WP_014681980 459 YRHQRFKI 466
WP_062542998 448 EFRLSYVV 455
WP_066402270 459 SPHQSFEV 466
WP_076378236 456 ELHEVCAL 463
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