Conserved Protein Domain Family
Methyltransf_34

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pfam11312: Methyltransf_34 
Putative SAM-dependent methyltransferase
This family of largely fungal proteins are likely to be a methyltransferase. This was determined through multiple motif screening in yeast.
Statistics
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PSSM-Id: 431804
Aligned: 80 rows
Threshold Bit Score: 288.318
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EER43806      86 LSDRDsktealsrpLSELVQILKTHLYHRDFISAFADanEELLKAYALRWSAGRALGYAGIFASVLEMIIQHRTV----V 161
XP_009153904  55 EQQD----------VKAAIQEVKGHLYQRDFAAAFAK--QEYLEAYAFRWSSSRALGYSDIFLHGNLQEVWQGGAacnaT 122
XP_003856418  26 SEDSN-----------TTLQEVKGHLFNRDFAAAFGK--EEYLRVYAGRWSPSRALGYTQILLDV--QDLIASGK----S 86 
EME50200      59 NQDV------------TILQEVKGHLYNRDFAAAFGQ--EDFLRVYASRWSPSRALGYVQTLTDI--QDELFDLS----N 118
EME87332      55 EHST------------AIVQEVKGHLYTRDFAKAFGT--AEYLNVYAARWSPSRALGYMQILSDI--SKDLFLEQ----D 114
XP_003840233  56 FETD----------INPLLQEVKGHLYNRDFATAFGS--QRYLEAYAARWSPSRALGYAEVFWDI--KEYLRPSD----E 117
Q0TWR4        58 FAAD----------IKPLLQEVKGHLYNRDFATAFGK--NEYLEAYAARWSASRALGYADLFLDL--KSQLWPES----A 119 Parastagonospor...
EFQ88647      61 LSSD----------FAPLLQEVKGHLYNRDFATAFGK--KEYLEVYAARWSPSRALGYLDLLWEL--RDHLEFVD----E 122
EMD64900      63 LSID----------FGPLLQEVKGHLFNRDFAAAFGK--EEYLEMYAARWSPSRALGYLDLFWDL--RQELGFDL----E 124
EOA87492      63 LSTD----------FGPLLQQVKGHLYNRDFATAFGK--TEYLEMYAARWSPSRALGYLDLFWDL--REPLEFTP----K 124
EER43806     162 AGDDKAGQ-------HVVCIGGGAgAEIAGLAAAWRwlhdggisnapaavtsdraaefssmnnnfrnisvenemepaqip 234
XP_009153904 123 SIEPSLTsa-----tTVACIGGGGgAEVAACAVAAR-------------------------------------------- 153
XP_003856418  87 DVDDDEEpp-----fRVLCIGGGAgAELVALATWAS-------------------------------------------- 117
EME50200     119 SVDNEAAGla----lNVVCIGGGAgAEVVALAGWIGv------------------------------------------- 151
EME87332     115 SQITDEGkd-----fRICCVGGGAgAELVAIGGWISq------------------------------------------- 146
XP_003840233 118 DSENENSDks----wKVVCLGGGAgAEIVALAGVQKmlsa---------------------------------------- 153
Q0TWR4       120 EEDAks--------rKIVSLGGGAgAELVALAGVQKml------------------------------------------ 149 Parastagonospor...
EFQ88647     123 DSDADGEEesgcksyKVVCLGGGAgAEVVALGGLQKllstla-------------------------------------- 164
EMD64900     125 ETIPNADGsdsvksrKVVCLGGGAgAEIVALGGLQKllagkmv------------------------------------e 168
EOA87492     125 EDAANGEEgmgsggwKVVCLGGGAgAEIVALGGLQKllcskd-------------------------------------s 167
EER43806     235 dtdteLAGQQPFSNFSITSIDIADWSSLVNTLNKAILSE----SIPSSMA--CPAPLipptnpesqvdGQFQVHFKKADV 308
XP_009153904 154 --------TYSLSKVDVHAIDIADWSSCLTKLRDTLSTPpalsTYASERAkaANKPLve--------rDQLKVTFSQRDI 217
XP_003856418 118 ------LEDTPFPRLQAKFLDIAAWGPVVTALHDAVTNApplsQYASAAAkeANEPLll--------pDAFKVTFQQQDA 183
EME50200     152 ----nTTGFGRLMKIDATLLDIAAWESVSNDLHRAIDTPaelsKYASAAAreANTAWlq--------sEIYKSSFRQLDA 219
EME87332     147 -----KEDALPFQRVNSTFVDIAAWNSVVSDLFRASTIPpdlsKYASAAAreANTALve--------qESYQIEFQQLDA 213
XP_003840233 154 --ardEVKASGEPKINITAIDVADWSTVVKNLAAQLETTptlsKYASAIAkaANAPLla--------pGSLEVTFDKHDV 223
Q0TWR4       150 ---sqDGQDQVPPTMNVEAIDIADWTVVMELLAKNVTTAptlsKYASAALqaANAPLin--------pDSFNVSFRQLDI 218 Parastagonospor...
EFQ88647     165 pqeqeDQEKKKPRRMEISAVDIADWSVVVENLAQHLTTTpvlsKYASAAAkaANVPFad--------pEDISITFHQHDV 236
EMD64900     169 qkegeDERAANVEKMEVTAVDIADWNVVVENLAKHLTTApilsKYASAAAkaANVSFld--------sAQISITFHQQDV 240
EOA87492     168 dkkdqDEKKKTMKKMEVTAIDIADWNVVVDNLAKHLTTAptlsKYASAAAkaANMSFme--------pEDIAITFHQHDV 239
EER43806     309 LKLTDQEMRSLFspprnvngdmkfdwlamkRNENMLVTLMFTLNELFLTSISMTTAFLLRLTDMLHPGTILLVVDSPGSY 388
XP_009153904 218 LAMERAELRATL-------------------DAVRLCTIMFTLNELFTSSISRTTALLLALTDIMQPGSWLLVVDSPGSY 278
XP_003856418 184 LEITDNKHCQQF------------------FGSNDLITMMFTLNELYSTSLAKTQQMLARVTASCRPGTILLVVDSPGSY 245
EME50200     220 LDLSEEQTRGIF-------------------AAADLVTLMFTLNELYSSSMAKTQQLLSKLTFVLRPGAHLLVVDSPGSY 280
EME87332     214 LALEDEKSHELF-------------------SKADMVTLMFTLNELYTASIPKTQKLLARLTAELRAGAYLLVVDSPGSY 274
XP_003840233 224 LAPESSDLSSYL-------------------KSASLVTLMFTLNELYTASLPLSQKFLLDLTAAMTPGSLLLVVDSPGSY 284
Q0TWR4       219 LNAATDVLSDMV-------------------KDATLVTLLFTLNELYSTSLSLTQKFLLNLTSALPSGARLLVVDSPGSY 279 Parastagonospor...
EFQ88647     237 LQASTPAINSQL-------------------AEASLVTLLFTLNELYTTSLPLTQKFLLHVTSVLRPGALLLVVDSPGSY 297
EMD64900     241 LQASASDMTSQL-------------------RDANLITLLFTLNELYSTSLPLTQKFLLQLTSIMEPGSLLLVVDSPGSY 301
EOA87492     240 LQASASDMTSQL-------------------AEAHLVTLLFTLNELYSTSLSLTQKLLLQITSVLKPGSLLLVVDSPGSY 300
EER43806     389 STVSFatskeNStqkssnsstpppsredhttrqdvkasatksnhpmsQRNYPMRFLLDHALLSVAd-----------GNW 457
XP_009153904 279 SEVKLgqgqdAK-----------------------------------TKQYPMKWLLDHTLLEVAglg-------enSKW 316
XP_003856418 246 STVSMn----GA-----------------------------------EKKYPMQWLLDFTLIGPPkkdlg--gaegsVKW 284
EME50200     281 STVSId----GA-----------------------------------ERKYPMQWLLDYTLIGSSkghe----aanqPKW 317
EME87332     275 SAVSVn----GA-----------------------------------EKKYPMQWLLDYTLVGTGwkgk----ddgrPQW 311
XP_003840233 285 SLLTLn----GA-----------------------------------EKQYPMQWLLDHTLLKQAngnqkvrgeeevPRW 325
Q0TWR4       280 STITLn----GA-----------------------------------EKKYPMQWLLDHTLLQTGekdk----nkeeATW 316 Parastagonospor...
EFQ88647     298 SSVTLn----GA-----------------------------------EKKYPMQWLLDHTLLNQAssnknergkeeiASW 338
EMD64900     302 SSVTLn----GA-----------------------------------EKKYPMQWLLDHTLLDQAssnknergkdeiASW 342
EOA87492     301 SSVTLn----GA-----------------------------------EKKYPMQWLLDHTLLKQAssntnergkeevASW 341
EER43806     458 ERVVSEDSRWFRRDTtLLKYQVgdgiGLEDMRVQIHVYR 496
XP_009153904 317 EKHVSDDSRWFRLSS-SLKYPI----ELENMRYQIHLYQ 350
XP_003856418 285 EKLLEDESRWYRLPP-GLKYPI----ELENMRYQIHIYR 318
EME50200     318 QKLVSDDSRWFRIPE-GLKYPI----ELENMRYQIHLYK 351
EME87332     312 QKLVSDDSRWFRLPQ-GLQYPI----ELENMRYQIHLYR 345
XP_003840233 326 EKLQEDESKWFRMDE-GLKYPI----ELENMRMQLHLYR 359
Q0TWR4       317 EKIHEDESRWFRLAP-TLRYPI----ELENMRMQLHLYR 350 Parastagonospora nodorum SN15
EFQ88647     339 EKITEDDSRWFRLDD-RLQYPI----ELENMRMQMHLYR 372
EMD64900     343 EKVKEDDSRWFRLDD-RLSYPI----ELENMRMQMHLYR 376
EOA87492     342 EKVKEDESRWFRLDD-RLKYPI----ELENMRMQMHLYR 375
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