3EIJ,3EIJ,1UG3


Conserved Protein Domain Family
MA3

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smart00544: MA3 
Click on image for an interactive view with Cn3D
Domain in DAP-5, eIF4G, MA-3 and other proteins.
Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Statistics
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PSSM-Id: 214714
Aligned: 35 rows
Threshold Bit Score: 79.9813
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EIJ_A        179 LVKEIDMLLKEYLlsgDISEAEHCLKELEV-P-H-F-HHELVYEAIIMVLEStG--ESTFKMILDLLKSLWKSSTITVDQ 252  human
XP_002822074  595 LLKLTETVVTEYLnsgNANEAVNGVREMRA-PkH-F-LPEMLSKVIILSLDR-S--DEDKEKASSLISLLKQEGIATSDN 668  Sumatran oran...
NP_178208     650 LRRTIYLTIMSSV---DFEEAGHKLLKIKLeP-G-Q-EMELCIMLLECCSQE----RTYLRYYGLLGQRFCMINKIHQEN 719  thale cress
NP_596256     412 LRKSIYLTIMSSV---DFEECCHKLLKIDL-P-EgQ-EIELCNMVIECNSQE----RTYAKFYGLIGERFCKLSRTWRST 481  Schizosacchar...
XP_001684710  568 HKREIFRCIATAA---DGLECFTMLMYRDP-GyT-R-FHDVCAVLLQCVYQE----RKYNPYYVQVLMRFCSAKPACAKT 637  Leishmania ma...
NP_496363     486 FRREVYLTMQSSL---DYQEAAHKLLKMKI-PdS-M-QNELCAMLVDCCAQQ----RTYERFYGMLIERFCRLRLEYQQY 555  nematode
NP_647717     651 eRRNIFCIIMSAA---DYVDAFEKILHLSL-K-D-Q-R-AVAYVIIHCALNE-K--R-ANPYYAHLALKFCQFNRKYQLA 718  fruit fly
NP_001033943 1166 VSEVKEDAAIPVTtpdRFTKLVDGFLELKL-P-E-KaLKDVCINLLMEVLDRvN--DVFLERAVRLLQTLRKQSNIKPNI 1240 fruit fly
NP_594036     566 LRTSIFVAL---VgseDYIDAWERVLKLHL-KrN-Q-LPEIAYVILHCVGNE-K---LYNPFYGLVALKCCTLQHNLKKS 635  Schizosacchar...
EEU05500      645 IRRAIFISIMSAQ---DYLDAFSKLEKLSL-K-NkQ-VLEIPRIVLHCLLAD-SgsNGYNHYYALVANKICERYSHLSKS 717  Saccharomyces...
3EIJ_A        253 MKRGYERIYNEIPDINL---------------D-----VPHSYSVLERFVEECFQAGIIS 292  human
XP_002822074  669 FMQAFLNVLDQCPKLEV---------------D-----IPLVKSYLAQFAARAIISELVS 708  Sumatran orangutan
NP_178208     720 FEKCFVQQYSMIHRLET-----------------------NKLRNVAKFFAHLLGTDALP 756  thale cress
NP_596256     482 YEQCFKNYYETIHRYET-----------------------NRLRNIALFFANLLSTDSIg 518  Schizosaccharomyces pombe 972h-
XP_001684710  638 LQFAIWDRFKSIRIENT---------------D-----I-AGYLNFACGIADLMQHGVYN 676  Leishmania major strain Friedlin
NP_496363     556 FEKLCQDTYSTIHRIDI---------------T--------KLRNLARLIAHLLSTDAID 592  nematode
NP_647717     719 FQFASWDRINDIEKLSK---------------P--------QIRNLASFLQQVILAAGLq 755  fruit fly
NP_001033943 1241 VVEIFKQVVNKMNEREA---------------L-----NPRIVSLVASLLAKTICEPALl 1280 fruit fly
NP_594036     636 FQFSLWDFFNELQPDDD---------------SeereiSMRRIVNLAKLYASLVIEAAQP 680  Schizosaccharomyces pombe 972h-
EEU05500      718 FQFLFWDVIKKFEDKEFdsesdtdeeddlddkE-----KLLRISNQGRFFGSLLANDILk 772  Saccharomyces cerevisiae JAY291
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