1K8K_A 5 LPACVVDCGTGYTKLGYAGNT----EPQFIIPscIAIKESAKVGDQAqrrv----------------------------- 51 cattle Q20329 178 ERILILELGSCSIRAGVLTTEp--sLPQSFFPa-IAVRTDDGKI------------------------------------ 218 Caenorhabditis ele... NP_588104 5 pKTIVLDNGAYHIKAGFAGGK------VVEIPn-CLTRSKDGN------------------------------------- 40 Schizosaccharomyce... NP_013747 7 DSILIIYPRSQTTLVQFGLNEetftVPELEIPt-QIYRTTRQDGS----------------------------------- 50 Saccharomyces cere... NP_014339 37 QSPIAIDFGSSKLRAGFVNHA----TPTHIFPn-ALTKFRDRKL------------------------------------ 75 Saccharomyces cere... NP_013186 3 TPPIVIDNGSYEIKFGPSTNK----KPFRALN--ALAKDKFGTSYLS--------------------------------- 43 Saccharomyces cere... NP_495681 3 LTTIIFDNGGHNMKIGTIDSE----SPRLVPN--SIVKAKHEKK------------------------------------ 40 nematode NP_511165 3 NAVVVLDNGAHTAKVGLANQD----EPHVVPN--CIMKAKSERR------------------------------------ 40 fruit fly NP_014784 266 TATIVIHPGSNSIKIGFPKDD----HPVVVPN--CVAVPKKWLDLENsehvenvclqreqseefnniksemeknfrermr 339 Saccharomyces cere... EGA82224 52 VSAVVIDPGSYTTNIGYSGSD----FPQSILPs-VYGKYTADEG------------------------------------ 90 Saccharomyces cere...
1K8K_A 52 --------------------------------------------mkgvDDLDFFIGDEA---IEKPTY-------ATKWP 77 cattle Q20329 219 -----------------------------------------------------FVGEDAy-rPEIRHNgdfvrpiSATDP 244 Caenorhabditis ele... NP_588104 41 ---------------------------------------------------RLFLGNEL---ANCNDFtt----lQFRRA 62 Schizosaccharomyce... NP_013747 51 ---------------------------------------------------YTYHSTNK---DNKAEL---------IKP 67 Saccharomyces cere... NP_014339 76 ------------------------------------------------NKNFTFVGNDTlldQAVRSQ--------SRSP 99 Saccharomyces cere... NP_013186 44 -----------------------------------------------------NHIKNI---KDISSI-------TFRRP 60 Saccharomyces cere... NP_495681 41 ---------------------------------------------------RVFVAHEQ---EECSDKfs----lFYVRP 62 nematode NP_511165 41 ---------------------------------------------------RAFVGNQI---DECRDTsa----lYYILA 62 fruit fly NP_014784 340 yykrkvpgnaheqvvsfnenskpeiisekndpspiewifddsklyygsDALRCVDEKFVi-rKPFRGGs-----fNVKSP 413 Saccharomyces cere... EGA82224 91 -------------------------------------------------NKKIFSEQSI---GIPRKDy------ELKPI 112 Saccharomyces cere...
1K8K_A 78 IRHGIVEDWDLMERFMEQVIFK-----------Y--LRAEP---EDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 141 cattle Q20329 245 SVERYSIDKDVLKAVIGKVTK------------E--LKVEP---WKYKVLLSIPQNIPTVLIGELLQICLEDIKFQSAGI 307 Caenorhabditis ele... NP_588104 63 HEKGYLVHWSTETAVWDLVMRN-----------VgvMEPSM---ADYSLLLTQPVFTMPSIEHNTIQLVFEEFQFDAYLP 128 Schizosaccharomyce... NP_013747 68 IQNGEIIDISAFTQFLRLIFVSilsdranknqdA--FEAELs--NIPLLLITHHSWS-QSDLEIITQYVFESLEINNLIQ 142 Saccharomyces cere... NP_014339 100 FDGPFVTNWNLTEEILDYTFH------------H--LGVVPdngIPNPILLTERLATVQSQRTNWYQILFETYNVPGVTF 165 Saccharomyces cere... NP_013186 61 HELGQLTLWELESCIWDYCLFNpse------fdG--FDLKEg--KGHHLVASESCMTLPELSKHADQVIFEEYEFDSLFK 130 Saccharomyces cere... NP_495681 63 IERGYVVNWDTQQQIWEKTFGSm----------D--VEAST-----SRIALTDNNYLIPALPDVSSEILFDYFGFTEVHK 125 nematode NP_511165 63 FQRGYLLNWHTQKTVWDYIFSKd----------G--IGCSL---ENRNIVITEPQMNFQSIQEATLEILFEEYKVDGVYK 127 fruit fly NP_014784 414 YYKSLAELISDVTKLLEHALNSe----------T--LNVKPtkfNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVAI 481 Saccharomyces cere... EGA82224 113 IENGLVIDWDTAQEQWQWALQN-----------E--LYLNSn--SGIPALLTEPVWNSTENRKKSLEVLLEGMQFEACYL 177 Saccharomyces cere...
1K8K_A 142 AV----QAVLALAASwtsrq----------------------------------vgerTLT--------------GTVID 169 cattle Q20329 308 TR----QPSLILYAYd------------------------------------------VTT--------------GVVVD 327 Caenorhabditis ele... NP_588104 129 CT----PAELIPWDHg------------------------------------------SFTmnqedaytgqhgecVLVID 162 Schizosaccharomyce... NP_013747 143 L-----PASLAATYSmi----------------------------------------sLQN--------------CCIID 163 Saccharomyces cere... NP_014339 166 GI----DSLFSFYNYnp---------------------------------------sgNKT--------------GLVIS 188 Saccharomyces cere... NP_013186 131 SP----VAVFVPFTKsykgemrtisgkdedidivrgnsdstnstssesknaqdsgsdyHDF--------------QLVID 192 Saccharomyces cere... NP_495681 126 TS----ASTLVAKHSnki--------------------------------------nnEKC--------------AVVVD 149 nematode NP_511165 128 TTaadlAAFNYVADSeert------------------------------------tmeSLN--------------CIIID 157 fruit fly NP_014784 482 IQ----ESLATCYGAg-----------------------------------------iSTS--------------TCVVN 502 Saccharomyces cere... EGA82224 178 AP----TSTCVSFAAg------------------------------------------RPN--------------CLVVD 197 Saccharomyces cere...
1K8K_A 170 SGDGVTHVIPVAEGYVIGSCIKH--------------------------------------------------------- 192 cattle Q20329 328 IGERV-NIVPVIDGYVVESAICS--------------------------------------------------------- 349 Caenorhabditis ele... NP_588104 163 SGYSFTHIIPVIDFSVQEQAVKR--------------------------------------------------------- 185 Schizosaccharomyce... NP_013747 164 VGTHHTDIIPIVDYAQLDHLVSS--------------------------------------------------------- 186 Saccharomyces cere... NP_014339 189 CGHEDTNVIPVVDGAGILTDAKRinwgghqavdylndlmalkypyfptkmsylqyetmykdycyvsrnydediekiltle 268 Saccharomyces cere... NP_013186 193 SGFNCTWIIPVLKGIPYYKAVKK--------------------------------------------------------- 215 Saccharomyces cere... NP_495681 150 SGFSWTTVASFVNGMLIQDSVIr--------------------------------------------------------- 172 nematode NP_511165 158 VGYSFTHVVPFVLGRRVLQGIRR--------------------------------------------------------- 180 fruit fly NP_014784 503 IGAAETRIACVDEGTVLEHSAIT--------------------------------------------------------- 525 Saccharomyces cere... EGA82224 198 IGHDTCSVSPIVDGMTLSKSTRR--------------------------------------------------------- 220 Saccharomyces cere...
1K8K_A -------------------------------------------------------------------------------- cattle Q20329 -------------------------------------------------------------------------------- Caenorhabditis ele... NP_588104 -------------------------------------------------------------------------------- Schizosaccharomyce... NP_013747 -------------------------------------------------------------------------------- Saccharomyces cere... NP_014339 269 nldtndvvveapftevlqpqkteeelriqaekrketgkrlqeqarlkrmeklvqkqeefeyfskvrdqlidepkkkvlsv 348 Saccharomyces cere... NP_013186 -------------------------------------------------------------------------------- Saccharomyces cere... NP_495681 -------------------------------------------------------------------------------- nematode NP_511165 -------------------------------------------------------------------------------- fruit fly NP_014784 -------------------------------------------------------------------------------- Saccharomyces cere... EGA82224 -------------------------------------------------------------------------------- Saccharomyces cere...
1K8K_A -------------------------------------------------------------------------------- cattle Q20329 -------------------------------------------------------------------------------- Caenorhabditis ele... NP_588104 -------------------------------------------------------------------------------- Schizosaccharomyce... NP_013747 -------------------------------------------------------------------------------- Saccharomyces cere... NP_014339 349 lqnagfdderdfkkylhsleqslkkaqmveaeddshldemnedktaqkfdlldiadedlnedqikekrkqrflkasqdar 428 Saccharomyces cere... NP_013186 -------------------------------------------------------------------------------- Saccharomyces cere... NP_495681 -------------------------------------------------------------------------------- nematode NP_511165 -------------------------------------------------------------------------------- fruit fly NP_014784 -------------------------------------------------------------------------------- Saccharomyces cere... EGA82224 -------------------------------------------------------------------------------- Saccharomyces cere...
1K8K_A -------------------------------------------------------------------------------- cattle Q20329 -------------------------------------------------------------------------------- Caenorhabditis ele... NP_588104 -------------------------------------------------------------------------------- Schizosaccharomyce... NP_013747 -------------------------------------------------------------------------------- Saccharomyces cere... NP_014339 429 qkakeekervakeeeekklkeqqwretdlngwikdkrlklnklikrrkeklklrdemkdrksqvsqnrmknlaslaednv 508 Saccharomyces cere... NP_013186 -------------------------------------------------------------------------------- Saccharomyces cere... NP_495681 -------------------------------------------------------------------------------- nematode NP_511165 -------------------------------------------------------------------------------- fruit fly NP_014784 -------------------------------------------------------------------------------- Saccharomyces cere... EGA82224 -------------------------------------------------------------------------------- Saccharomyces cere...
1K8K_A 193 --------------------------IPIAGRDITYFIQQLLRD------------------------------------ 210 cattle Q20329 350 --------------------------IPYGSQQMGDSLRASLSAhn---------------------------------- 369 Caenorhabditis ele... NP_588104 186 --------------------------VDVGGKLLTNYLKEVISY------------------------------------ 203 Schizosaccharomyce... NP_013747 187 --------------------------IPMGGQSINDSLKKLLPQwdddqieslk-------------------------k 215 Saccharomyces cere... NP_014339 509 kqgakrnrhqatidndpndtfgandeDWLIYTDITQN-PEAFEE------------------------------------ 551 Saccharomyces cere... NP_013186 216 --------------------------LDIGGRFLTGLLKETLSF------------------------------------ 233 Saccharomyces cere... NP_495681 173 --------------------------IDVGGKALTNKLKDWVSY------------------------------------ 190 nematode NP_511165 181 --------------------------IDMGGKALTNQLKELISY------------------------------------ 198 fruit fly NP_014784 526 --------------------------LDYGGDDITRLFALFLLQsdfplqdwkidskhgwllaerlkknfttfqdadvav 579 Saccharomyces cere... EGA82224 221 --------------------------NFIAGKFINHLIKKALEPkeiiplfaikqrk-------------------pefi 255 Saccharomyces cere...
1K8K_A 211 --------REVGIPPEQSLETAKAv-kERYSYVCPDLVKEFNKydtdgs------------------------------- 250 cattle Q20329 370 -------kGLYAFQSPVEKLILRFa-lEQTTYVPEDYQKEEKSenke--------------------------------- 408 Caenorhabditis ele... NP_588104 204 --------R--KYNMMEETYIVNEi-kESVCYVSQNFKEDMEIchek--------------------------------- 239 Schizosaccharomyce... NP_013747 216 spifevlsDDAKKLSSFDFGNENEdedEGTLNVAEIITSGRDTrevleererg--------------------------- 268 Saccharomyces cere... NP_014339 552 ---------ALEYEYKDIVELERLl-lEHDPNFTEEDTLEAQydwrn--------------------------------- 588 Saccharomyces cere... NP_013186 234 ----------RHYNMMDETILVNNi-kEQCLFVSPVSYFDSFKtk----------------------------------- 267 Saccharomyces cere... NP_495681 191 ----------RQLNVSEETYVINEc-kEDLCFVSQNFDESMKEarnr--------------------------------- 226 nematode NP_511165 199 ----------RHLNVMDESHVVNQi-kEDVCFVAEDFKQAMQVhyse--------------------------------- 234 fruit fly NP_014784 580 qlynfmnrSPNQPTEKYEFKLFDE---VMLAPLALFFPQIFKLirtsshknsslefql---------------------- 634 Saccharomyces cere... EGA82224 256 kktfdyevDKSLYDYANNRGFFQEc-kETLCHICPTKTLEETKtelsstakrsiespwneeivfdnetrygfaeelflpk 334 Saccharomyces cere...
1K8K_A 251 -----------------kwikqYTGINAISKKEFSIDVG----------------------YERFLGPEIFF-------- 283 cattle Q20329 409 ------------------trisLDAFTPSPGMQTRFDID----------------------NSRFLCTEGLF-------- 440 Caenorhabditis ele... NP_588104 240 -------------------prsKLEICYALPDYSTGKHGyivrdinqk----ieqqvlnlsNERFMIPELLF-------- 288 Schizosaccharomyce... NP_013747 269 ------------qkvknvknsdLEFNTFWDEKGNEIKVG----------------------KQRFQGCNNLI-------- 306 Saccharomyces cere... NP_014339 589 -----------------silhlFLRGPRPHDSENIHEQHqmh-----------------lnVERIRVPEVIF-------- 626 Saccharomyces cere... NP_013186 268 ---------------------dKHALEYVLPDFQTSFLGyvrnprkenvplpedaqiitltDELFTIPETFF-------- 318 Saccharomyces cere... NP_495681 227 ------------------fqenTTMKRYIMPDFHSTFRGvvkdvkephd---pqipsihlgVERFAIPEILF-------- 277 nematode NP_511165 235 ------------------ekrrEVTVDYVLPDFTTVKRGyvrvpgkpred-eeqqqmvslcNERFTVPELLF-------- 287 fruit fly NP_014784 635 --------pesrdlftnelndwNSLSQFESKEGNLYCDL----------------------NDDLKILNRILdahniidq 684 Saccharomyces cere... EGA82224 335 eddipanwprsnsgvvktwrndYVPLKRTKPSGVNKSDKkvtpte----------ekeqeaVSKSTSPAANSadt----- 399 Saccharomyces cere...
1K8K_A 284 ---HPEFANPDFTq---------PISEVVDEVIQNCP-------IDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVD 344 cattle Q20329 441 ---KPKKWGLDTK----------GLHQLIHEAILQCP-------IDSRRTLYRNIYLAGGASLMPGIAEKLEQELSTVVP 500 Caenorhabditis ele... NP_588104 289 ---SPSDIEIREA----------GIPEAVMQSVTHFP-------ENIQAMLLENVVTIGGNCKFPGFHKRLSSELRSLAP 348 Schizosaccharomyce... NP_013747 307 -------KN--------------ISNRVGLTLDNIDD-------INKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHL 358 Saccharomyces cere... NP_014339 627 ---QPTMGGQDQA----------GICELSETILLKKFgsqpgklSQTSIDMVNNVLITGGNAKVPGLKERIVKEFTGFLP 693 Saccharomyces cere... NP_013186 319 ---HPEISQITKP----------GIVEAILESLSMLP-------EIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLP 378 Saccharomyces cere... NP_495681 278 ---NPSDIDIDQC----------GVAEAVIESICQCP-------EALRPALAENIIVIGGSSCFPGFRERLEREVRSMLP 337 nematode NP_511165 288 ---NPSDIGVQQV----------GIPEAVADCLKACP-------WEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVP 347 fruit fly NP_014784 685 lqdKPENYGNTLKen------faPLEKAIVQSIANASit---adVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRP 755 Saccharomyces cere... EGA82224 400 -pnETGKRPLEEEkppkenneliGLADLVYSSIMSSD-------VDLRATLAHNVVLTGGTSSIPGLSDRLMTELNKILP 471 Saccharomyces cere...
1K8K_A 345 arlklsee---------------------------------------------------lsggrlkpKPIDVQVITHHMQ 373 cattle Q20329 501 -------------------------------------------------------------------NTIHTQVNISPWR 513 Caenorhabditis ele... NP_588104 349 -------------------------------------------------------------------ANWEVKVFEPSDP 361 Schizosaccharomyce... NP_013747 359 iiepeeekskre-------------------------------------------eeaksvlpaatkKKSKFMTNSTAFV 395 Saccharomyces cere... NP_014339 694 -------------------------------------------------------------------TGTNITVNMSSDP 706 Saccharomyces cere... NP_013186 379 -------------------------------------------------------------------TDWTCHVSVPEGD 391 Saccharomyces cere... NP_495681 338 ae---------------------------------------------------------------ygLNVSNDVINPQ-- 352 nematode NP_511165 348 -------------------------------------------------------------------DDLEVSLICPEDP 360 fruit fly NP_014784 756 sllssasfpqfykkltkeikdleghyvnapdktedenkqilqaqikekiveeleeqhqniehqngneHIFPVSIIPPPRD 835 Saccharomyces cere... EGA82224 472 s-----------------------------------------------------------------lKFRILTTGHTIER 486 Saccharomyces cere...
1K8K_A 374 R---YAVWFGGSMLASTPEFYQ-VCHTKKDYEEIG-----PSICRHNPV 413 cattle Q20329 514 Y---NAAYLGAQIVASASTFED-SCISLQQLPKF------LAQLQSSSF 552 Caenorhabditis elegans NP_588104 362 I---CFPWKKASHM-PLEHWNA-NKITRSEYSEHG-----ANIMTRKRR 400 Schizosaccharomyces pombe 972h- NP_013747 396 P---TIEYVQCPTVIKLAKYPD-YFPEWKKSGYSEiiflgAQIVSKQIF 440 Saccharomyces cerevisiae S288c NP_014339 707 S---LDAWKGMAALARNEEQYRkTVISKKEYEEYGp----EYIKEHKLG 748 Saccharomyces cerevisiae S288c NP_013186 392 Ca--LFGWEVMSQFAKTDSYRK-ARVTREEYYEHGp----DWCTKHRFG 433 Saccharomyces cerevisiae S288c NP_495681 353 ----THSWHCGQELLTASKVP---WINRKDWDERG------DSLEFSNF 388 nematode NP_511165 361 v---RYAWYGGKEVATSPNFEE-FVYTQDDYEEYG-----FQGINQR-- 398 fruit fly NP_014784 836 MnpaLIIWKGASVLAQIKLVEE-LFITNSDWDVHG-----SRILQYKCI 878 Saccharomyces cerevisiae S288c EGA82224 487 Q---YQSWLGGSILTSLGTFHQ-LWVGKKEYEEVG-----VERLLNDRF 526 Saccharomyces cerevisiae Lalvin QA23
Jiyao W et al.(2023). "The conserved domain database in 2023.",