Conserved Protein Domain Family
DUF4729

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pfam15866: DUF4729 
Domain of unknown function (DUF4729)
This family of proteins is functionally uncharacterized. This family of proteins is found in insects. Proteins in this family are typically between 238 and 666 amino acids in length.
Statistics
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PSSM-Id: 434981
Aligned: 37 rows
Threshold Bit Score: 105.855
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9W4H1               33 AQCPIEKCISTVFKDDMLQHLAQRHFR-Sn---V-KKHLQVAFNGERCTLVFDVSQLIGTQTICLGVLLYGGVRGkhSQL 107 fruit fly
WGS:AAPP:GF20345-PA  31 IRCPLSGCLATISSLDILCHMLIQHLRpS----PgKEELHLAYENERCILLFDLSRLPPRKTICLGVLLYCGKRDhpDGL 106
Q9W4G5               18 AICPLADCQAVVEHTHLLRHMITKHLDpRartlPfQLRLREVSTGQRTLLMLPYRQLIIDNDQCLAVLNWSSV------- 90  fruit fly
XP_001963339         21 AVCPVGNCRTIVAHTHLLRHMISDHLDpRaralPfQLRLREVAIGQKTMLMLAYRQLVLDRDYCLAVLNWRQP------- 93 
XP_003425697        262 IQCPLLDCAVNVAFSALTNHFIFDHp---------EVPILIVDPGEKSTLVVNFDGLVYDSSRCLALLLVSGKls----- 327
EGI65026             33 IRCPRLDCSVNVAFSALTHHFLFDHp---------EVPILSVEPGAESTLIVSYGALSCNSSRCLALLLVSGKls----- 98 
WGS:AAPU:GI12019-PA 557 IFCPDSECRRMFFISDFNDHLTHEHp---------ALPMERIAPCMAKTFFLDTRVTMLNQAKCNMVYF----------- 616
WGS:AANI:GJ13288-PA 589 IFCPDADCRRMFFISDFNDHLTHEHp---------SLAMERITPCKAKTFFLDTRVTLLNKAKCNMVYF----------- 648
XP_002068442        510 VFCPDDDCKRITFIADFNRHLLYDHr---------ALTMERINVRQSKTFYLDSNVVLLNKPKCHILYL----------- 569
XP_001957158        559 IHCPDHDCKRLSFISDLNKHLLLEHr---------ALTMERIGVRQTKTFFLDSTMVLLNKPKCQMLYM----------- 618
Q9W4H1              108 PGEREFC-----YHNR-LKEDSGleSLKDYLPIMVLVKRTTFLCWalvdrkmesqedlngKQSKDLKQVKHLDFSNDthp 181 fruit fly
WGS:AAPP:GF20345-PA 107 PGKRGLC-----HLNRfLPEAENelLLAEYLPVVILVRRCYFFEW---------------LDKKKKDPAPVFEDMSDwtr 166
Q9W4G5               91 ------SqgdltAPQLdLPPCHQ--MLTYHLPILVMVCRTTWKSL---------------LKQIDEKDMQETRDVTAe-- 145 fruit fly
XP_001963339         94 --DIKLGpgelaPEQLdLPPCHQ--PLAGHLPVLVMVCRTTWKAL---------------LTHEDRTIRSEQYAIGArhp 154
XP_003425697        328 -----------gPAAKqFNGSHIhpRYKNRLPLPILAARLHCNAShdggetg---------------------------- 368
EGI65026             99 -----------dSSARlFGSIQInpKYRNRLPLPVLAARLHSSHNyacheemh--------------------------- 140
WGS:AAPU:GI12019-PA 617 ------------VKDKfFDSNSN--KHPDLLPVLIMTARMQITEF---------------FSLRDSETLTNNNACNTcc- 666
WGS:AANI:GJ13288-PA 649 ------------VKDKfIDKNTE--KYPDLLPVLVMTARLHAPDF---------------FTSNNPAKPRSTARAGGs-- 697
XP_002068442        570 ------------IREKvIDTHSK--KLRELLPVLVMTSRVRLSEM---------------FGPSSAVELHGVSHQAL--- 617
XP_001957158        619 ------------VRDKiIDTQGD--DLKDLLPVLVMTARANLAEA---------------LAPTKGHSSDRVLKRIKag- 668
Q9W4H1              182 kcseesikrcdsgqknndlkttteaeqeeimDSDILIIWTQSAPC--I-RPLHVAMTVFNSTLSVG-RSAMRCVANs-gQ 256 fruit fly
WGS:AAPP:GF20345-PA 167 knvt---------------------yeadkdELDMFLFWTQSVSC--T-RPLHVTMTAYDRTMSEC-RSGFRQVVNs-gM 220
Q9W4G5              146 -------------------------------WGGVYLFWLLSPLT--R-RPIYANLALLNSQIQSVyRRNRRRIRN---F 188 fruit fly
XP_001963339        155 d--------------------------psreWGTVYLFWLLCPAT--R-RPVTATLTVLNSELECIeRRNRRRIRN---F 202
XP_003425697        369 -------------------------kgnhedGGDVVIAWVAGLDIgnS-TTLRCSIQAIDSIDGEAfRSL---TYTg-pI 418
EGI65026            141 ------------------------aggegqcEKDMIIAWVAGLDIgdTaDRLRCSIQAVDNIENGGfRSL---TYTg-pV 192
WGS:AAPU:GI12019-PA 667 -----------------------------ipDQEIFMLWLTSVRP--DdIKIVGTVSLWPTRSRPIiEYLMVHTNEaynI 715
WGS:AANI:GJ13288-PA 698 -------------------------------DQEIFLIWLTSIRP--DdVKIIGTISVWPTSSRPIvEYLMVQTNE---V 741
XP_002068442        618 -------------------------------NAEMFVIWLTSFIP--RdHNVIGTICVWSTDKTQLvNSLYVHTSD---V 661
XP_001957158        669 ------------------------------eDREVFLIWLTSIIP--RdMCLMGTLSLWSTTGFKIiDCLSVNTSH---M 713
Q9W4H1              257 ---MYTEIGGKDLP-KDRHSLLITQQELKEI---CGA-EHHLHLE 293 fruit fly
WGS:AAPP:GF20345-PA 221 ---IRPESDGKELP-KSKHALWVTCSEMEQMgkgKGGdKKSVNLE 261
Q9W4G5              189 ---ASRMPIRQFINgLDPYFVSINEDQLDELc--NGG-GNRFSIY 227 fruit fly
XP_001963339        203 ---ACRMPIEQFINgLDPTFVTINEEKMDRCc--RGTgrgdkasa 242
XP_003425697        419 nslRTAQKPKEVF--LTGDCVILHDGFINHIt--SGC----KNLN 455
EGI65026            193 tslRVTQCPRDVF--LAGDCIVLHEGLISHIt--SGC----TSLN 229
WGS:AAPU:GI12019-PA 716 ---RAAQSLKDIY--GSNRAITVPGSIISRMt--NNG-ENLLAVQ 752
WGS:AANI:GJ13288-PA 742 yniRSAQKLKTIY--NSNRVMALPGNFVNRMt--DGG-KHLLAVQ 781
XP_002068442        662 ydiRDPQDLCSIC--SSTSSLVIPGHVVNRMt--NHG-GNFLAVQ 701
XP_001957158        714 ydiRAPLDMGTIC--RSPSTLMLPMQMISKMt--DKG-ANFLVVQ 753
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