2HDW


Conserved Protein Domain Family
FrsA

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COG1073: FrsA 
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]
Statistics
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Structure
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COG1073 is classified as a model that may span more than one domain.
COG1073 is the only member of the superfamily cl27027
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2HDW_A        59 TFp-------L--SAKVEHRKVTFANRYGITLAAdLYLPKN---RGG----DRlPAIVIGGPFGAVKEQSSgLYAQTMAE 122
NP_461482     34 FYypdnkvy---gptpaeaESITFTAKDGTHLHG-WFIPTAfgrPEN----AV-ATVIHVHGNAGNMSAHW-PLVSWLPE 103
NP_743657     31 LFypergqaftperAKLEYRDVTLTTADGIRLHG-WWLPAKa--GVE----VK-GTVLHLHGNGGNLPGHL-GGSYWLPE 101
YP_404266     43 FYypddkiy---gpdpwsaESVEFTAKDGTRLQG-WFIPSStgpADN----AI-ATIIHAHGNAGNMSAHW-PLVSWLPE 112
WP_012702449  25 LFypepgqpltpraAGLDYRDLYLRAADGTRLHA-WWLPARa--GRE----VR-GTVLHLHGNGGNLAWHL-GGSWWLPE 95 
WP_055734190  22 YYspkaggdmA--LEGYTYDSFFLPSDSGNQLHS-VFIATK---DLN----SK-GLVVHFHGNSGNISETV-EKYLWLSD 89 
WP_008250528  38 LFfpqqqllrtpadVGLSYSDVQITVDDSATLHG-WWLPAV----GD----AT-ATLLFAHGNAENISTHL-ASVYWLPA 106
WP_068545313  28 FFyperklvrtpaeISLAYEDVYIDSTDGERLNG-WFLKVEq--GIE----AK-GTIYFLHGNAQNISHHI-ASVYWLPK 98 
WP_085751690  36 FFhpndreysepekLGLVSHDIEFRAEDRSPLDG-WWLPA-----DPkagpPI-CTVVHAHGNAANISRHL-EAVAWLPP 107
WP_085759337  23 LFfpskqwvrtpadINLAYEDIELVTADNIKLSA-WWLKT----DQP----VK-GTVLFLHGNAENISTHI-ASVHWLPE 91 
2HDW_A       123 RGFVTLAFDPSYTGESGGQPRNVASPDinteDFSAAVDFISLL-PEVNRERIGVIGICGWGGMALNAVAV---------D 192
NP_461482    104 RNVNLFMFDYRGFGESEGTPSQEGLLD----DTKSAIDYVRHR-ADVNPERLVLLGQSLGGNNVLAAVGHcvgcanmryA 178
NP_743657    102 QGYQVLMIDYRGYGLSQGQPSLPEVYQ----DIAAAMAWLQQA-PEVKGKPLVLLGQSLGGAMAIHYLAA---------H 167
YP_404266    113 RNFNVFMFDYRGFGKSKGTPSQAGLLD----DTQSAINMVRHR-SDVNPQRLVLFGQSIGGANILAVIGQ---------G 178
WP_012702449  96 QGWQVLLLDYRGYGLSEGSPALPEVYQ----DLEAAFAWLGSE-PAVRDRPLAVLGQSLGGALAVHFLAQ---------R 161
WP_055734190  90 AGYDLLLFDYSGYGHSSGRANFANLRA----DAQSVFRFVEQQfASSENYSLISIGTSLGGAVMLDGLIE---------S 156
WP_008250528 107 QGVNVLLIDYRGYGGSLGRPSVASAQE----DILASLVWLQDQ-PPLQETPILVLGQSLGASLAGVVVAR---------H 172
WP_068545313  99 AGYQVFMLDYRGYGRSTGTPVIPDVFN----DIIAGFNYLETR-ADVANKPMYVLGQSLGASMSGYVVGA---------N 164
WP_085751690 108 LGVNVLMFDYRGFGLSLGKPSLDGVVA----DTEAAVHTALQM-PGATPGRLFVFGQSLGGATAIRAVAE---------L 173
WP_085759337  92 RGYQVLMLDYRGYGRSEGTPSLPAVFM----DIEAGFNWLKNS-EDVAGKPVFLLAQSLGAAMGGFSVGD---------N 157
2HDW_A       193 K----R--V-KAVVTSTMYDmtrvmskgyndsvtleqrtrTLEQLGQQRWKDAesGtpayqppynelkggeaqflvdyhd 265
NP_461482    179 D----QagI-RAIILDSTFL--------------------SYSSIANQMi------------------------------ 203
NP_743657    168 PeqrqR--F-SALVFDGVPA--------------------SYRAVGRFALSTSw-M------------------------ 199
YP_404266    179 D----RegI-RAVILDSTFA--------------------SYATIANQMi------------------------------ 203
WP_012702449 162 PqrraR--L-SALVLDGVPA--------------------SYREVARHMLGGAw-L------------------------ 193
WP_055734190 157 Qqr----eLfDLVVVDSSFH--------------------SFTEVAQHVVSQN--------------------------- 185
WP_008250528 173 RsefaN--L-AGVILDAGFT--------------------GYSAIAKTVAAANy-V------------------------ 204
WP_068545313 165 SeinqR--L-SAVVLDAGFT--------------------SYSDISQTIAARSw-L------------------------ 196
WP_085751690 174 Ppg----lV-QGLIVDSGFA--------------------RYRDVAHHVANEIk-V------------------------ 203
WP_085759337 158 PefrnM--L-NAVVLDAGFG--------------------SYSEIAKEVASRSw-L------------------------ 189
2HDW_A       266 yYMTPRgYH-----PravnsgnawtmTT-PlsFMN---MPILTYIKEISpRPILLIHGER--AHSRYFSETAYAAAAEPK 334
NP_461482    204 --------------Pg----------SG-Y--LLDd-rYSADRNIASVSpIPVLILHGTAdhVIPWQDSEKLYALAREPK 255
NP_743657    200 -TWP---LQv----P-----------LS-W--LVPd-gDSAIRSIERLSsPPKLFFHSIDdnLVPMDNGIRLYQHAPPPR 256
YP_404266    204 --------------Pg----------SG-Y--LLDe-sYSGENYIASVSpIPLLLIHGKAdhVIPWQHSEKLYSLAKEPK 255
WP_012702449 194 -TWP---LQv----P-----------LS-W--LVPd-gDSAVDAMPRLQgLPVLIYHSRDdeLVPLSNGLRLYRAAAPPR 250
WP_055734190 186 ---PLG-FLgawliP--------------L--VVDe-qYNPLPRLQHLAnTPLLFVHCESdaLIPWQFSEKMHQQSLKNS 244
WP_008250528 205 -TWP---FQc----P-----------VA-W--AMPk-gQDLIAEVAEIApLPLLLIHGRSdpVVPYANAVALYAAAASPR 261
WP_068545313 197 -TWA---FQy----P-----------VA-W--SMPs-dYDLIDVIANISpTPLLIIHGKQdrIIPYQHSQQLVKKAGQPK 253
WP_085751690 204 -LKL---Fa-----P-----------IVrE--TLPgseDDPVTAIPNVH-VPVWIIQGDAdrTVPFFQGVDLFEAAREPK 260
WP_085759337 190 -TWP---FQy----P-----------VA-W--SMPd-eYNLDAVIHQISpTPLLIIHGTQdaVIPFAEGERLFGLAVKPK 246
2HDW_A       335 ELLIVPGASHVDLYDRLd--RIPFDRIAGFFDEHL 367
NP_461482    256 QKIFIPDGDHIDAFSGRy-aNLYRDAMIKFIQTAL 289
NP_743657    257 VLQLTRG-GHVQTFAd----PTWRQVMLRFLDDPS 286
YP_404266    256 RLILIPDGEHIDAFSDRh-gDVYREQMVDFILSAL 289
WP_012702449 251 FFQPTRG-GHVQTFAe----PAWRALMLRFLADPR 280
WP_055734190 245 NLELLQGCKHARTFTPEs--SENRPRLLSYLSQLE 277
WP_008250528 262 QLLSYDG-GHIETFNHPhagMQNRATVMDFIRKAV 295
WP_068545313 254 AMLSYNG-AHIQTFNd----VGNQQLLLEFLDKYK 283
WP_085751690 261 TWVRVVGGEHLDAMTr----PEVRAIVWQALREVC 291
WP_085759337 247 SFLRYDG-PHIGTFYd----VGNRDLLLQFFNNST 276
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