6B4F


Conserved Protein Domain Family
GLE1

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pfam07817: GLE1 
GLE1-like protein
The members of this family are sequences that are similar to the human protein GLE1. This protein is localized at the nuclear pore complexes and functions in poly(A)+ RNA export to the cytoplasm.
Statistics
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PSSM-Id: 462280
Aligned: 75 rows
Threshold Bit Score: 175.852
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6B4F_A               29 SK-------DSQAKKIKMDLQKAATIPVSQISTIAg---SKLKEIFDKIHSLL---SGKPvqsggr--svsvtlNPQGLD 93 
EPB86195            231 Q--------NDVFRKQCFQAKLVIKRTVSQLQADHkvvaEKFNTLNNHLLGIKq--QS-----------------PEAFE 283
EGC39101            480 PTq------SKENLDYEKQLTKNINIAINQISASK----EQTESKAKRLTDILgneKRNN---------------EYFYK 534
KRH31359            346 ELcegnqmiRSSYNEDCTRHEGRISRNIRQIRGIS----DNVRSKASELTKLLs-------------------hPQSFQS 402
XP_002960959        432 NEaskslqaNPVLRKNLKALGFQIGKLWNQVAATE----EQVRKVSMEFLQLAnnpQSQP-------------------- 487
XP_001987229        376 vdavkplqtDEAWKKYRTNCQRTINVPLNAITAASa---QHLTTNFDKLYNFF---AGQPvrttdgttitindhPLA-RD 448
Q9V4W1              387 vdavkplqtEESLKQYRTGCQRAINLPLNAISAVSp---QHLAQNFDKLYSFF---AGQPtkvmngt-itindhPLA-RD 458 fruit fly
WGS:AAQB:GK16987-PA 419 veivkplqtNEALKQYRTNCQRAINMPLNAISAVSp---QHLQQNFDKIYNFF---NGQPvkimnq--sitindHPLARD 490
XP_003248018        391 kksyssfleNDNLKPLRQELVKAINTPVNSISSVSs---WHMKDKFEKLDALL---KCKTvktgnst-vtanshPDA-LI 462
XP_015364451        306 svrelpfvnDPTTKVFRQNVIKVINTLVNTISTTNv---THLTDKYNKLNALL---SGKLvcvantq-vmvgenKEA-LA 377
6B4F_A               94 FVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWELHPRVGDLILAHLHKKCPYSVPFyp---tfKE-GMA------L 163
EPB86195            284 YMLNQLAKFLLAQAKQEIHATAFAAYFLARFAYLMFSSIPEFLPYLMGRLMKRCPYLIPQyh---ddDP-SLS------H 353
EGC39101            535 RALISIANKSMDQVESQITFHTASAFPLSDVLIKVGKQFPELFKIILGKLEEHCMYTVPMyst-------------liqG 601
KRH31359            403 ISIEIFAKKVVAYCANPA----NVPFASAYVIVLVTSQVPHAMDILLAELHRACIYTVPKhlv--ykKSaYQS------K 470
XP_002960959        488 FVVSTLASKLMSQCEAQVLRAPSYAFVFARIVVNVSSQLPVVMDAVLAHLNVVCILTVPKyf---myKKvTFSsfffpcD 564
XP_001987229        449 YCILLMAKKFVSQTDTAISSNPQAAFPFASVIVTFWRLLPDFGKIFLAYMYKESPYLVPYvi---pqQS-GQT------P 518
Q9V4W1              459 YCMLLMAKKFVSQTETAICSNPQAAFPFASVIITFWKLLPDFGKVFLAYMYKESPFLVPYvi---pqQQ-GQT------P 528 fruit fly
WGS:AAQB:GK16987-PA 491 YCLLLVAKKFVSQCETSISSNPQAAFPFASVINTLWKLLPDFGKIFLAYMYKESPFLVPYvi---pqHS-NQT------T 560
XP_003248018        463 FCKDTLAKKIINIGEQVASVKTETAFEVASIVTELWKIHPDFGILLYARFKQICPCLIPYna---ekTN-EET------D 532
XP_015364451        378 FCMETLATKIVNYAEEVICVKTQAAYEIATIITKLWNVHQQFGKILFAVMKQKCPLLVPFyhpiakhLIcEQL------D 451
6B4F_A              164 EDYQ---RMLGYQ-----V--KDS-KVEQQDNFLKRMSGMIRLYAAIIQLRWP-------------YGNRQEIHphglNh 219
EPB86195            354 DEIK---SRLRYA-----IknKEKkTLETFLEHAEGQKCYVMFYGALCQTLPD-------------SGQPENPFpikhA- 411
EGC39101            602 EDKNislQKAGYLfneetKk-----PAETDEEFNKRMCGYISLFTSLILKSEQpstatmfgfgsaaTASNAPNTlfnlDl 676
KRH31359            471 EAYF---RSIGYRe-------DDE-KMESTEDYLKRLESYMKMYGALVQT-----------------EITNCQNfhglKe 522
XP_002960959        565 KSYY---NMLGFR-----Ed-DSG-TLETADDYVARMTAYVTLYAAITQT--------------------GGTNghgiAn 614
XP_001987229        519 EQYL---KTMGYR-----Ls-ENN-ELEKPDMFLKRQTGIARLYAAVIITPGR-------------KA-DGSAHcfglEe 574
Q9V4W1              529 EQYL---KTIGYR-----Lt-DKN-ELEKPDIYLKRQTGLARLYAAVIISQGR-------------KA-AGPDEcfelNe 584 fruit fly
WGS:AAQB:GK16987-PA 561 EQYL---KTIGYR-----Ls-EKN-ELEKPDIYLKRQTGLARLYAAVIMT-PS-------------RKSDGPAHcfglEe 616
XP_003248018        533 EEYY---KSLCYN-----Y--TNG-VVEKQDKYVKRMTGIVRLFAAIIVT------------------ESKSGKalgiGq 583
XP_015364451        452 ---H---KSFGYK-----Fd-SLG-NVESDAKYLQRMTGIIRLYASLIVTSSK-------------CD----QPviglSh 501
6B4F_A              220 gWRWLAQILNMEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMLILIK 268
EPB86195            412 -WIWLARICNMp-pREITPILVNGLLEVSAIRLLQAYPNQTAKLFRLIR 458
EGC39101            677 aLKWLHGIVHL-KPRRITSYLLVAFLSQMGNILFK---KQKQNLFEILQ 721
KRH31359            523 gWAWLARFLNTHPANQYTAVSLNAFLQMAGFALYNRYKSQFLKMLNVVS 571
XP_002960959        615 gWKWCAQLLNHLPANRYSASALFAFLETAGFRLYQSYPKPFMKLMNTIV 663
XP_001987229        575 aWCWLTHIMNVTPLPDICATMIMEMLQTLGFELWRAYGRNFLKLLLYIQ 623
Q9V4W1              585 gWLWLAHMVHVKPLPDISATLIMEILQTLGFELWRTYGKQFVKLLVYIQ 633 fruit fly
WGS:AAQB:GK16987-PA 617 gWRWLAHFVMVQPLPDVSATLMMEMLHNLGFDMWRTYGKQFVKLLLFIQ 665
XP_003248018        584 aWMLIAATVHLVPQLDVTAVFLHEILIITGYSLKQTYGRQFIKMLEYIN 632
XP_015364451        502 aWIFVAGTLNQNPVADITATLLVEFLKIVGFVMHQGYGNQFIKLLQHIN 550
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