5JJ3


Conserved Protein Domain Family
P22_portal

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pfam16510: P22_portal 
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Phage P22-like portal protein
The portal protein of P22 and similar Podoviridae tail phages is a dodecameric structure consisting of a hip (2), a leg(1) and a barrel(3). DNA viruses such as bacteriophages and herpesviruses deliver their genome into and out of the capsid through large proteinaceous assemblies, known as portal proteins. Domains 1 and 3 are mostly helical and form the majority of the DNA-translocating channel. Domain 2 adopts an alpha-beta-fold characterized by two sheets of eight beta-strands, which cross each other to form a beta-barrel-like structure.
Statistics
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PSSM-Id: 293119
Aligned: 3 rows
Threshold Bit Score: 1072.67
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5JJ3_D        14 RFDADWTASDEARREAKNDLFFSRV--SQWD------DWLSQYTTLQYRGQFDVVRPVVRKLVSEMRQNPIDVLYRPKDG 85  Salmonella viru...
ACQ68289      15 KFDRAHSPQEAVREKCLEATRFARVpgGQWEgetaagSELGKHFEKYPKFEINKISTELNRIVSEYRNNRITVKFRPGDK 94 
CCH:MU9_2904  14 KFDLDYSASEAARTEARNDLFFSRV--SQWD------DWLENYVTLQYRGQFDVVRPMVRKLVAEMRKNPIEVQYRPKDT 85 
5JJ3_D        86 ARPDA-ADVLMGMYRTDMRHNTAKIAVNIAVREQIEAGVGAWRLVTDYEDQ-SPTSNNQVIRREPIHSACSHVIWDSNSK 163 Salmonella viru...
ACQ68289      95 AASEAlANKLNGLFRADYEETDGGEACDNAFDDGSTGGFGCFRLTTNLVNAlDPMDERQRICLEPIYDPARSVWFDPDAK 174
CCH:MU9_2904  86 ASPDA-ADILMGMYRTDMRNNSSKISVNVAVREQIECGVGAWRIVTEYEDD-NPTSNNQIIRRKPIHESCTHVIWDCNAK 163
5JJ3_D       164 LMDKSDARHCTVIHSMSqngwedfAEKYDLDADDIPS--FQNPN-DWVFPWLTQDTIQIAEFYEVVEKKETAFIYQDPVT 240 Salmonella viru...
ACQ68289     175 KYDKSDAEWAFCMYSLS-------AEKYKAEYNKDPAtlMSGIErSWDYDWYDVDVVYIAKYYEVKKESVDVVSFQNPLT 247
CCH:MU9_2904 164 EMDKSDAKRCTIIHALNidgweefAEQYGLDPDDVPT--FQSPNtDWLFTWSSGKTIYVAEHYEVDEKNEKVFVYYNPTV 241
5JJ3_D       241 GEPVSYFKRDIKDVIDDLADSGFIKIAERQIKRRRVYKSIITCTAVLKDKQLIAGEHIPIVPVFGEWGFVEDKEVYEGVV 320 Salmonella viru...
ACQ68289     248 SETVTYDSDQLELVEDELADIGFIEAARRTIKRRRVYVSVVDGEGFLEKAQRIPGEHIPLIPVYGKRWFIDDIERVEGHI 327
CCH:MU9_2904 242 MDFQSYYASEIKDHIERLSAEGAEKAGERKVKRRRVYKSIITSTAILKDKIPVAGEHIPIVPVYGEWSFFDDTELYEGVV 321
5JJ3_D       321 RLTKDGQRLRNMIMSFNADIVARTPKKKPFFWPEQIAGFEHMYDG-NDDYPYYL-LNRTDENSGDL--PTQPLAYYENPE 396 Salmonella viru...
ACQ68289     328 AKAMDAQRLYNLQVSMLADSATQDTGSIPIVGKSQIKTLEKYWANrNKNRPAFLpLNEIVDKQGNIiaPPTPVGYTQPQP 407
CCH:MU9_2904 322 RLSKDAQRLRNFILSKGADTVAKSPKKKPFFYAEQIAGYEHMYSG-DDDYPYYI-LNRTDENSQDL--PPGPVSYMENPE 397
5JJ3_D       397 VPQANAYMLEAATSAVKEV--ATLGVDTEAVNggqVAFDTVNQLNMRADLETYVFQDNLATAMRRDGEIYQSIVNDIYDV 474 Salmonella viru...
ACQ68289     408 LNQAMAALLQQTGADIQEVtgSSQAMQPMPSN---IAKETVNNLMHRSDMSSFIYLDNMAKSLKRAGEVWLSMAREVYGS 484
CCH:MU9_2904 398 ISPADAGMLDAATQAAKEV--ARIGVDPSAANg-qVAFDTVNQLNSRIDLETYVFQDNLAIAMRRDGEIYASIASEIYDT 474
5JJ3_D       475 PRNVTITLEDGSEkDVQLMAEVV-DLATGEKQVLNDI-RGRYECYTDVGPSFQSMKQQNRAEILELLGKTPQGTPEYQLL 552 Salmonella viru...
ACQ68289     485 DRQVRIVNADGTD-DIALMSVVInDNQTGQVVAMNDLsSGRYDVTVDVGPSYTARRDATVSVLTNLLAGMLPQDPMRQVL 563
CCH:MU9_2904 475 TRTVVTTAEDGNEsNVELMSQTV-DFQQGQVVTKNDI-RGKYETYTDVGPSFQSQKDAARAEIGDLITKVPPEHPMWNVM 552
5JJ3_D       553 LLQYFTLLDGKGVEMMRDYANKQLIQMGVKKPETPEEQQwlVEAQQAKQGQQ-DPAMVQAQGVLLQGQAELAKAQNQTLS 631 Salmonella viru...
ACQ68289     564 QGIILDNMEGEGLDEFKEYNRKQLLTQGVVKPRNTEEEQ--MVAQMIQQAQQpNAELVAAQGVLMQGQAEVQKAKNEELA 641
CCH:MU9_2904 553 MLTYANMMEGKGVEYIRDYANRELIVNGLKKPETDEEQRwlMEAQQAQQGKQ-DPMMIAAMAEQKKAEAELVSAQTRAQE 631
5JJ3_D       632 LQIDAAKVEAQNQLNAARIAEIFNNMDLSKQSEFREFLKTVASFQQDRSE 681 Salmonella virus P22
ACQ68289     642 IQVKAFQAQTEARVAEAKMVQILASADSAKRAEIREALKMLHQFQKEQGD 691
CCH:MU9_2904 632 TQIKAFTAQNNALESQANTTLTLAKAEDLQQGAVMKAIELLSKVAEQQQQ 681
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