1PSW


Conserved Protein Domain Family
Glyco_transf_9

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pfam01075: Glyco_transf_9 
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Glycosyltransferase family 9 (heptosyltransferase)
Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
Statistics
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PSSM-Id: 395853
Aligned: 13 rows
Threshold Bit Score: 197.552
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1PSW_A        69 RRKLGHSLREKRYDRAYVLPNSFKSALVPLFAGIPHRTGWRGEXR---YGLLNDVRVLDKEa-WPLXVERYIALAYDKgi 144 Escherichia coli
Q57336        73 VLSLWKQLKNKQFDALLNMQTAFRASILSLGIKAKFKIGFGEKRSr-eGQWLFVNRRIRDP--FSPHVLDGFMAFAEY-- 147 Haemophilus inf...
O25802        77 IHKLAQKIGRC--DIAITLNNHFYSAFLLYATKTPVRIGFAQFFR-----SLFLSHAIAPApkEYHQVEKYCFLFSQF-- 147 Helicobacter py...
Q5F815        71 RWRVGRELGRRGYDRVIVLPGSLKSAVIALATGIGKRTGYVGESR---YFLLNDIRRLDKEr-LPLMVDRYTALAHQSq- 145 Neisseria gonor...
1_pfamImport   1 RRRIGRGLRGQ-YEQAILLPNSLKSALVPWFAGIPKRTGWRGEMR---YGLLNDIRKLDKQr-YPLMIERFMALAFEPg- 74 
O25056        71 IFKLFKSLRAYEYDIIIDMQGLVKSALITQMLKAPKKVGFDYASAregLSMFFYSQKVSIAy-DEPVLKRNFTLLSHA-- 147 Helicobacter py...
P45042        69 RYRLGKSLREQ-YDMAIVLPNSLKSAFIPFFAKIVHRRGWKGESR---YILLNDLRANKKD--YPMMVQRYVALAFEKdv 142 Haemophilus inf...
Q5F5J0        75 MGRLKQALLQEAFDFVLDSQGLIKSACFAK-MAKSPIYGLDKHSAregVAALAYDKKYVVPk-GRNAVWRNRDLFAQV-- 150 Neisseria gonor...
Q9HUF5        75 WRRFKQRLKEVDYDLVIDAQGLLKSAWLTRYVGKTPVAGLDRDSArepLASRFYRRAYPVAw-GQHAVERTRQLFAQA-- 151 Pseudomonas aer...
P26469        75 RTAFRRAVCANQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTArepLASLFYNRKHHIAk-QQHAVERTRELFAKS-- 151 Salmonella ente...
2_pfamImport   1 RRALAERLRSVSYDVVLDMQGLLKSAWLVR-QTRGVRHGLDWRSArepLVSLFYNVRHRVEf-WQPAVVRQRKLAALT-- 76 
P25742        64 VLSLIKTLRANNYDLVINLTDQWMVALLVRCLPARMKISQLYGHRq--HGIWKKSFTHLAPihGTHIVERNLSVLEPLg- 140 Escherichia col...
3_pfamImport   1 -AAHRRALGGGAATRGLLLPDSLSSAAVFR-LAGIPCAGYRDDGR-----SPLLRWPVDKPgaSLHAVQSWHYLTRAAlq 73 
1PSW_A       145 xrtaQDLPQPLLWPQLQVSEGEKSYTCNQFSl---------sSERPXIGFCPGAEFg---PAKRWPHYHYAELAKQLIDE 212 Escherichia coli
Q57336       148 ----IGVPKAEPKWELAISQDDYKFADQFID-----------FSRKNLLISPCSSK----AEKDWLIEGYAEVANIAHQH 208 Haemophilus inf...
O25802       148 ----LEKEL-DQKSVLPLKLAFNLPTHTPNT------------P-KKIGFNPSASYg---SAKRWPASYYAEVSAVLLEK 206 Helicobacter py...
Q5F815       146 ----EDFDGHSGFPEFSIDERRREISVETFGl---------nLGKPVLAFCPGAEFg---PAKRWPARHFAELGKHYSEA 209 Neisseria gonor...
1_pfamImport  75 ----VELPKPYPQPRLRIDDGSRQAALDKFAl---------sLDRPVLALCPGAEFg---EAKRWPAEHYAAVAEAKIRA 138
O25056       148 ----LNLPQKEISKEISESLSSRAKAFSYQPspkid-alnlnKNKPKILFILETSK----INKTYPIERFKELALILENF 218 Helicobacter py...
P45042       143 ipkaDDIP--VLKPYLTVEPAQQAETLKKFEkqt-----allGERPIIGFCPGAEFg---PAKRWPHYHYAKLAEMLITQ 212 Haemophilus inf...
Q5F5J0       151 ----FGYAMPETQ-VFGLSVPEASRLKNLAQ--------------PYYAALHATSR----DSKLWPMENWRELLQKLNQK 207 Neisseria gonor...
Q9HUF5       152 ----LDYPLPESVGDYGLDREQLADADPGA---------------PYLVFLHGTTW----VTKHWPEAYWRELAERMCER 208 Pseudomonas aer...
P26469       152 ----LGYDKPQSQGDYAIAKHFLHCQQAVSD--------------PYAVFLHATTR----DDKHWPEANWRELIGLVGNT 209 Salmonella ente...
2_pfamImport  77 ----FGYNYAGSP-DFGLQAFGRAAQADDAPadpgrrmlhlaADRGYAVIMPSASR----DDKLWPEDDWRAVFRRLQDA 147
P25742       141 ---iTDFYTDTTMSYAEDCWKKMRRELDALG-----------VKDHYVVIQPTARQ----IFKCWDNDKFSKVIDALQQR 202 Escherichia col...
3_pfamImport  74 ---rWGLPAGPVEPGALLDLPLTQAHRDAAGqllq---aqqlAGRPFVLIAPTATGlhkgKVKVWPG--FDALTRALQER 145
1PSW_A       213 Gy-qVVLFGSAKDHeaGNEILAALNTEQQa-----wCRNLAGETQLDQAVILIAACKAIVTNDSGLXHVAAALNRPLVAL 286 Escherichia coli
Q57336       209 Ni-nVIFCSSPAKR--ELEIVEKITALCHf-----tPTNIAGKTNLKQLTALISKVDLVLSPDSGPAHIATTQGTPVIGL 280 Haemophilus inf...
O25802       207 Gh-eIYFFGAKEDAivSEEILKLIKGSLKnpslfhnAYNLCGKTSIEELIERIAVLDLFITNDSGPMHVAASMQTPLIAL 285 Helicobacter py...
Q5F815       210 Gw-qVWLFGSQKD----NEIAEEINCLSDg-----mCVNLCGKTDLSQAMDLLSLADTVVCNDSGLMHLAAALGRKVVAV 279 Neisseria gonor...
1_pfamImport 139 Gw-qVWLFGSKNDHpgGEEIRQRLIPGLRe-----eSFNLAGETSLAEAIDLMSCAGAVVSNDSGLMHVAAALDRPLVGV 212
O25056       219 Q---ICLLWHADEY--KATTLYHALKHQR-------DVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITL 286 Helicobacter py...
P45042       213 Gy-aVALFGSAKDEpvGEEIRQALPEELRe-----fCVNLAGKTNLNEAVDLIANCTAVVTNDSGLMHIAAAVNRPLIAL 286 Haemophilus inf...
Q5F5J0       208 QqcnVYLPWGNEA---EKVRAEQIADGLP-------FTIVCAKMNLLQAAYLLKHAVGIVGVDTGLLHLANALEKPVVGI 277 Neisseria gonor...
Q9HUF5       209 Gw-sVRLPWGSAA---ERERAGRLAAGLE-------NAAVLPRLSLAGMAKVLAGARACVAVDTGLGHLAAALDVPTLSL 277 Pseudomonas aer...
P26469       210 Gl-rIKLPWGAPH---EEARAKRLAEGFD-------YVDVLPRMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITL 278 Salmonella ente...
2_pfamImport 148 Gc-aLRLLAGNEQ---EAERARVLVAGME-------GVEVLPRMDLTSVAQVLAGARLMVGLDSGLTHLSAALGRPTIGI 216
P25742       203 Gy-qVVLTCGPSAD--DLACVDEIARGCEtk----pITGLAGKTRFPELGALIDHAVLFIGVDSAPGHIAAAVKTPVISL 275 Escherichia col...
3_pfamImport 146 Gq--TVVMCPPPA---EVAEARRNAPS----------ATLLPPLGLGAFAALAQRAALVVCNDSGVSHVAAAVDARQLTL 210
1PSW_A       287 YGPSSPDFTP----PLSHKARVIRL-ITG-YHKVRKGDAAEGYH 324 Escherichia coli
Q57336       281 YAYHNPLRTA----PYNNLDNVVSVyEENaQKEFGKPSSELPWA 320 Haemophilus influenzae Rd KW20
O25802       286 FGPTDEKETR----PYKAQKTIVLNhHLScAPCKKRVCPLKNAK 325 Helicobacter pylori
Q5F815       280 YGSSSPTHTP----PLSDRAKIVSL-HLEcSPCFKRECPLghtd 318 Neisseria gonorrhoeae FA 1090
1_pfamImport 213 YGSTSPQFTP----PLADRVEIVRL-GLEcSPCFERTCRFGHY- 250
O25056       287 YGNTPMERFKle-sPINVSLTGNSN-ANYhKKDFSIQNIEPKKI 328 Helicobacter pylori
P45042       287 YGPTSPQYTP----PLSDKATIIRL-IEGeLIKVRKGDKEGGYH 325 Haemophilus influenzae Rd KW20
Q5F5J0       278 YTDTDPIKTGvqvsAIAKNVGNIG--QIP-TADLVYQTLMDCVs 318 Neisseria gonorrhoeae FA 1090
Q9HUF5       278 FGPTNPGFTG----AYGRSQVHLGS-DFPcAPCLKKTCTYQPte 316 Pseudomonas aeruginosa PAO1
P26469       279 YGPTDPGLIG----GYGKNQMACCS-PEQnLANLDATSVFGKIH 317 Salmonella enterica subsp. enterica serovar Typhimu...
2_pfamImport 217 YRASTPVRTP----LVGPSYTASLG-DRGaSPSRE--------- 246
P25742       276 FGATDHVFWR----PWTENIIQFWAgNYQkMPTRHELDRNKKYL 315 Escherichia coli K-12
3_pfamImport 211 FGVTRPGRTG----PWSPRAVCLGSeTRWpGPEQVMEKSLELL- 249
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