4G07,6AN0


Conserved Protein Domain Family
HisD

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COG0141: HisD 
Histidinol dehydrogenase [Amino acid transport and metabolism]
Histidinol dehydrogenase is part of the Pathway/BioSystem: Histidine biosynthesis
Statistics
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PSSM-Id: 439911
Aligned: 922 rows
Threshold Bit Score: 371.662
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4G07_A         2 VTTLrq--tdPDFEQKFAAFLSGKREVSEDVDRAVREIVDRVRREGDSALLDYSRRFDRIDL--EktGIAVTEAEIDAAF 77 
WP_013008661   1 -mIF------FPDSEKIKDIINRGEVLEADYLDTVQDILNDVKLNGDKALIKYTSQFDKYNLe-E--KFYFDREELKVFF 70 
WP_041722856   1 MKILkg---kRELEQFLSNLDSIGYQTVEEIEDKVKRIIADVKLKKDEAILNYTRLFDCKEFdlE--DLIVKEEEIDRAF 75 
WP_012513934   2 IAIEdftikdFKSSKILEKILNRAKVFEQQYLDKVREIIENVIKYKDEALYKYALEFDNIDLkkE--GIEIPKEAIENAY 79 
YP_002249608   1 MQIIk----dKKIfEKFVKKLQKRSFSEPKIEDSVRKILNDIKKSGDKALARYTKLFDKHSL-----PLKIGKKEIEKKA 71 
WP_013009752   1 -mII------RKDDKRLQDILKRGEIMEGEYLHTVLDIIADVRTRGDESLAELTLRFDGYDMlkG--GIEISKREMKDAW 71 
WP_013451397   1 -mIY------KDTNEILPKILKRSDDYEEKYLSTVLSIIDDVKKNGDSALKIYSKKFDNNPd--E--NLEVTKKEMISAY 69 
WP_013885644   1 -mII------DKNSDKLNKILNRGELFDEKYLSVVMDILKDVRINGDKAVKSYTKKFDNHDLn-E--SYVIGVDELKSSF 70 
WP_068549009   1 MEVIk-----PEGLADLLSILKSHSFVDPTITRTVLDIIEEVKSRGDEALIEFTRRFDRWDPs-N--GFEATEGDLEKAW 72 
WP_128465499   1 -mII------KRNDEKLKIILGRGESFNEQYMDTVLSIINRIRKEGDTALFELTKKFDRFDC--E--KVEITRKEMEKAY 69 
4G07_A        78 D---AAPASTVEALKLARDRIEKHHARQLPKDDRYTDALGVELGSRWTAIEAVGLYVPGGTASYPSSVLMNAMPAKVAGV 154
WP_013008661  71 D---EIPEDLKTAFVNAKGNIELFHSNQKEKTFL-VESKGAILGQKVTPIDSVSVYVPGGKASYPSTVLMNVIPAKVAGV 146
WP_041722856  76 FecqKEDNKFVQALELAYENIYQYHLKQKEETWLFTKGD-TILGQIVRPLERVGIYVPGGNGSYPSTVLMNSIPAKVAGV 154
WP_012513934  80 K---DLDENTKKALQFSYERVYKFHENQKEKSFM-VEEDGMILGQRVLPVESAGLYVPGGKAAYPSSVIMNAVPAKVAGV 155
YP_002249608  72 K---DISKDVFNALIFAEERIRKFHEKQLEKSWQ-YQEGDIILGQIIRPLERVGAYVPGGKASYPSTVLMNIIPAQVAGV 147
WP_013009752  72 E---ALDDRLKLALENAKANVISFHEKQLENTWIYEKTPGTFLGQKVTALESVGVYVPGGKAVYPSSVLMNVLPAKVAGV 148
WP_013451397  70 D---NIDEQLKLDLQLAKKNIEEYHKNQLEKSWF-IEKEGTILGQKITPLDKVGVYVPGGKASYPSTVLMNVIPAKVAGV 145
WP_013885644  71 D---KLESGLKDSLIKAEKSIRFYHEKQMEKTWLINGNNGIVLGQKISPVENVGIYVPGGKAVYPSSVLMNSVPANVAGV 147
WP_068549009  73 A---SLEDDVKRALLKAKERIEVYHRQQIEKSWFFEEGK-SLLGMLIRPVDRVGVYVPGGRAAYPSTVLMNVIPAKVAGV 148
WP_128465499  70 K---NLDPKLKKALEKAKDNIVSFHEKQLEKTWIYEKSEGTFLGQKITPLERVGVYVPGGKAVYPTSVMMNTLPAKVAGV 146
4G07_A       155 DRIVMVVPAP-DGNLNPLVLVAARLAGVSEIYRVGGAQAIAALAYGTETIRPVAKIVGPGNAYVAAAKRIVFGTVGIDMI 233
WP_013008661 147 NRVVMTTPAS-NGEINRLVLGVAYLAGVDRVYLIGGAQAIAAVAFGTESVEKVDKIVGPGNIYVALAKKLVFGLVDIDMI 225
WP_041722856 155 KEIIMVTPPDkEKKINKYTLAAAKICGVNKIFKVGGAQAIAALAFGTELIPKVEKIVGPGNIYVAIAKKILFGNVDIDSI 234
WP_012513934 156 SNVYMVCPKP-----TKEVLAAAYICGVDRIFRVGGAQSIAALAYGTETIPAVEKIVGPGNIYVATAKRLVYGIVGIDMV 230
YP_002249608 148 KEIAVCVPTP-NGELNPIVCAALSILGIKEVYRIGGAQAIAAMAYGTETIKKVDKIVGPGNIYVATAKKLVFGEVDIDMI 226
WP_013009752 149 EEIVMVTPAT-GGKVNPVVLAAAYLAGVDRGFRIGGAQAIAALAYGTASVPRVNKIVGPGNIYVALAKKMVFGQVDIDMI 227
WP_013451397 146 KEVIVVTPAK-DGKISEIVLAACYIAGVDKIFKIGGAQAIAALSYGTETIPKVDKIVGPGNIYVALAKKLVFGRVDIDMI 224
WP_013885644 148 ENIVMSTPAA-YGKVQESVLAAAYLGGVKKVYKIGGAQAVAAMAYGTETVEKVDKIVGPGNIFVALAKKLVFGFVDIDMI 226
WP_068549009 149 PEVIMCVPTp-DGCKNPYVLGAAYIAGVDRVFFVGGAQAVAAMAYGTNTVSKVDKIVGPGNIYVAEAKRLVYGEVDIDSI 227
WP_128465499 147 KEIIMTTPAT-GGEVNPVVLAAAYIAGVDRGFKVGGAQAIAALAYGTATVPKVDKIVGPGNIYVALAKKLVFGQVDIDMI 225
4G07_A       234 AGPSEVLIVADKDNNPDWIAADLLAQAEHDTAAQSILMTNDEAFAHAVEEAVERQLHTLARTETASASWRDFGAVILVKD 313
WP_013008661 226 AGPSEILIIADESANPKYVAADMLSQAEHDELASAITITWDKELAIEIEKELDFQLKKLNRADIARKSLDKFGGILLVDN 305
WP_041722856 235 AGPSEVLIIADSFANPKYVAADLLSQAEHDAMARCILITTSQDLALEVNKKVDEMLKANPn-QIAAQSIERNGVIIIVED 313
WP_012513934 231 AGPSEVLIIADASADPSFIAMDMLSQAEHDELASAILITNCEDLAYSVAKEIDVFLSQLERKDIASKSIDNYGAIFIVKN 310
YP_002249608 227 AGPSEILIIADNSANPAFVAADMLSQAEHDEMACSILVTNSEQLVNSVKKEITRQLKKLPKASIAKESLKNFGAIIIVKS 306
WP_013009752 228 AGPSEILIVADSSADPDHVAADMLSQAEHDELASAIVVTDDLELAKEIESSVYAQLEELPKREIAKKSIEKYGAIIVTDD 307
WP_013451397 225 AGPSEILIIADDSANPEYVAADMLSQAEHDELASSITITDSPNLAKEIEKYLNIHLKSLPKKDIAEKSLKQYGGVIVVKN 304
WP_013885644 227 AGPSEITIIADESANPQFIAADMLSQAEHDEMASSVLITYSKKLAESVNAELKKQLEELPRKDIAEASLKDFGAIVLVEN 306
WP_068549009 228 AGPSEVLVIADGTVSAEWVAADLLSQAEHDPMARSILISLSKDYALEVLSEVEKQLVKLPTKEVAEESWRNNGVVVIAKD 307
WP_128465499 226 AGPSEVLIIADKSAKAKYIAADMLSQAEHDELASAVAVTDNKKLAEKIKEELEKQLEALPKKDIAKKSLDNYGAVILVKD 305
4G07_A       314 FEDAIPLANRIAAEHLEIAVADAEAFVPRIRNAGSIFIGGYTPEVIGDYVGGSNHVLPTARSARFSSGLSVLDYMKRTSL 393
WP_013008661 306 LDEAIEFANSIAPEHLELAVKNPFELLYKIKHAGAIFMGHFTPEAIGDYFAGPNHTLPTGGTARFYSPLGVYDFVKKSSI 385
WP_041722856 314 LDDAVEIANRICPEHLELCCKNSEDLIFKIKNAGAIFVGEFSPEPIGDYIAGPNHVLPTSGTARFFSPLGVYDFVKRISL 393
WP_012513934 311 LEKACELSNMIAPEHLEINTENPFELLGFIKNAGAIFLGEYTVEALGDYCLGPNHTLPTGRSARFSSALGVYDFVKRSSI 390
YP_002249608 307 LQEACNIANTIAPEHLEVMTENPEKLLPLLKNAGAIFLGQFTPEPIGDYVAGPNHTLPTSGTARFFSPLGVYDFVKKSSL 386
WP_013009752 308 LNEAADITNNIAVEHLELCVANPMEYMLKIRNAGAIFLGANSPEPVGDYYAGPNHVLPTGGTAKFFSPLGTYDFQKKSSI 387
WP_013451397 305 INEAVELSNSIAPEHLELAVKNPFELLPKIKHAGAIFLGHYTPEAMGDYFAGPNHTLPTGGTARFSSPLGTYDFFKRSSI 384
WP_013885644 307 LEEAAEVSDRIAPEHLELCVANPYELMFKVRNAGAIFLGHYTPEAVGDYIAGPNHTLPTGGSARFFSPLGAYDFLKRSSI 386
WP_068549009 308 IDEACEVANAIAPEHLELLVESPWEVVPKLKNAGAIFVGGYSPEPIGDYIAGPNHTLPTGGRARFSSPLGVYHFYKRTSL 387
WP_128465499 306 MDEACEVANVIAPEHLELYVESPMEMMLKIRNAGAIFLGENTPEAVGDYIAGPNHVLPTGGTARFFSPLGVYDFIKRSSI 385
4G07_A       394 LKLGSEQLRALGPAAIEIARAEGLDAHAQSVAIRLN 429
WP_013008661 386 INCSKEYLDKYGKLIVKMAESEGLEAHANSIKVRLE 421
WP_041722856 394 IKYSKEQFLKDAPFAIEIAQKEGFLFHANSLKVRLE 429
WP_012513934 391 LYVSKKGFDKVKHHAHNLAKIEGLHAHASSIELRGl 426
YP_002249608 387 IKVGENGFNKLAPYVEVLATLEGLHAHANTVKVRKT 422
WP_013009752 388 IYYSREQLIADMPDIRVLAESEELIAHRNSVIIRTE 423
WP_013451397 385 ISYTRDSFLKQRENVYRLAKSEDLDAHALSVKVRG- 419
WP_013885644 387 VNFTKDALRECAEDVMGIANSEELTAHAKSVKIRI- 421
WP_068549009 388 IAIDGELFLDLAYDAMKIAEVEGLIAHKRSIEKRVE 423
WP_128465499 386 LYYSKKQLEEDMEDIITLAEHEELIAHRNSASVRQK 421
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