4RSX


Conserved Protein Domain Family
HopA1

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pfam17914: HopA1 
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HopA1 effector protein family
This family includes the HopA1 effector protein from Pseudomonas syringae. Structurally this protein has an alpha + beta fold. The effector protein HopA1 was shown to affect the EDS1 complex by binding EDS1 directly and activating the immune response signaling pathway.
Statistics
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PSSM-Id: 436136
Aligned: 23 rows
Threshold Bit Score: 121.612
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4RSX_A          87 AESPDAKRFFYRIIPKHERR-EDKN----QGRLTIGV-QPQYATQLTRAMATLIGK--ESAITHGKVIGPACHGQMTDSA 158  Pseudomonas ...
EFL08888       137 AARPALSPGFFYVLGSQQRRrPDPA----VRRIFVHLtDPDGAVRVWRDVLRELES--LHADYHAKILSVRTGYPRRDAL 210 
BGI:SBI_01037  147 AVRPALSPGFLLVDGVDGRP-TDGAdr-eLLRMYVHLrYPDAAPRVWGALLAELAA--RSVPYRAKVLSRPWAYPRRDAI 222 
WP_016570561   134 SMRPGLSPGFFLVEGTRP-H-RSVD----LLRVYIHIkEWTAAPQIWQAALDHLEG--QELTYRTKVISSKLLYPRRDAL 205  Streptomyces...
WP_040022866   159 AARPSLSPGFFLVDGSQPLT-GQDP----ILRVYLHVrTADAALEAWGRTLRCLEG--LGVPFRAKAASSAHALPRRDGV 231  Streptomyces...
ODA70465       163 SARPLVSPGFFLVDSGTGRT-GGGD----LLRLYLRVaDADAAPELWRAVLSALES--RSVTYRAKIISNPASLPRNDGM 235 
ETD34044       157 SVESRLSLGFMFYTSTAGAG-HTSR----LLRLYRHLgDAEEAIEVWGSFTRWIEE--RRLPLRVKIVSRRSGFPRNDGM 229 
WP_006064156   140 SLNYRLSLGFTYYRNQYPPT-IATP----LLRVYRWAsRPEELLTSWSALIDLGER--GRFPLQMKMLSERESYPRNDAL 212  Corynebacter...
WP_034936497   201 QNSPMAEKDFIMFRRNNVSD-ADPH----LSRITLSV-HPQHAGQLPEMLHGLVRD--KDYLHTAKIAHPSFFGQDTDSV 272  Erwinia mall...
Q7N2F2         108 TDDALNNAEAFRMLPKDFAQ-RYGTrgklGARLTINV-NKAHFNLLARALPQLFNDnnRGWLEQAKIMGPKNLGSRTDQA 185  Photorhabdus...
4RSX_A         159 VLYIN-GDVAKAEKLGEKLKQMsgiPldAFVEHTPLSMQSLSKGLSYAESIL-----GDTRGHGMSRAEVISDA----LR 228  Pseudomonas ...
EFL08888       211 VIYLHgEYQSVETAIARRLRDD---R--ALGAATSVLAQRLARGVAAAWEPAdsrpgQQHLSFGQHRCFALATA----LV 281 
BGI:SBI_01037  223 VVYLDaDLADVVFPLAAAVHRL---P--GIGADTSVFAQRLLPGVAIAWEPRdtragWGGQSFGQHRAAAVAEG----VV 293 
WP_016570561   206 VVYLDqRDRHAAMGIADVVGGL---P--GIGEETSVFTRRLRPGVATAWEPRdsaagMGSLSFGQHRASVLAKA----LV 276  Streptomyces...
WP_040022866   232 VVYLGsGDQHVLPCLVEELKGA------VLGSEASPFTRPLAPGVAVAWEPDdsrpgMRNTSFGEHRSRALAAG----LI 301  Streptomyces...
ODA70465       236 VVYLSqGSWDAVGAVTEEALATg-----LPEGPAPAFAHEVAPGVTAAWEPKddrtgMRGLSFGEHRAHVVARA----FV 306 
ETD34044       230 VVYLPsESWHAVDDIADHLRSD---R---PHAPGSLFCRQLTNGVSMAWEPAdistpRRGTSFGEHRSNTIAKA----IV 299 
WP_006064156   213 VVYISgSGLQFLEEIVHLLSTE---N---TVATTSLFARKVANGVSLAWEPHdpasyRKQLSFGEHRSEQLARG----VI 282  Corynebacter...
WP_034936497   273 ILYLN-GHLGEALNLADEIQKKl--PrdAMVNHNPAGMYRMSKGFSYAEISE-----NDVSSYGMSRAAIIGSA----LT 340  Erwinia mall...
Q7N2F2         186 VIYLSkAGIEHAQTISEKLSELl--PatAFVEHTPTGMYRVGKGISYSETAA-----GGSSSHGQSRAQLIAAAgtqsLL 258  Photorhabdus...
4RSX_A         229 Md-----GMP---------FLARLKLSLSANGYDPDNPAL 254  Pseudomonas syringae pv. tomato str. DC3000
EFL08888       282 DhaldpvEGT---------RELRITAEFRAAGIDPLRPQR 312 
BGI:SBI_01037  294 RyaadreRTD---------LAREIAASLHSAAADPEEPAR 324 
WP_016570561   277 Eta--dvPGS---------LAEVLHDQLVAANIDPTDPSR 305  Streptomyces albulus
WP_040022866   302 Rhv--tqH-PaeadgphpnRSGCVREALLEAGVDPLDPAR 338  Streptomyces sp. 150FB
ODA70465       307 AaaeqqrERP---------TAAGLAAACVAANVDPADPAR 337 
ETD34044       300 Aegl-taAPD---------LAKAVRRQLITANIDPVAVYR 329 
WP_006064156   283 Rsi--rdSIP---------VASAIRATLLQGNIDPSNPSR 311  Corynebacterium durum
WP_034936497   341 Dk----tQGN---------FEKRLDFQLAAKGYDPKHPAF 367  Erwinia mallotivora
Q7N2F2         259 T------DIP---------IEKTLTHTLQTRGYDVHNPAL 283  Photorhabdus laumondii subsp. laumondii
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