Conserved Protein Domain Family
Nop52

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pfam05997: Nop52 
Nucleolar protein,Nop52
Nop52 believed to be involved in the generation of 28S rRNA.
Statistics
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PSSM-Id: 461800
Aligned: 119 rows
Threshold Bit Score: 140.033
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCF50301       44 IPLGKALASTEKRIRDSAVRSLHSFLATNGah----------------------tI-PELELQKLWKGLFYCFWMSDKPL 100 
XP_649440      10 KIIAQKLSNEEPSIRDAGWKEAKEVLMKKD-------------------------T-NEEVMKEIWIGLYFWYWHSDGRD 63  
Q236Y1         23 AIIAKKLSAIVPANTKEVIEEVKSYLDSQK-------------------------L-DKDGYRQIWKGIFFAMWASDKVP 76   Tetrahymena t...
XP_002140253    9 IRLGKTMTSIHANSRRRGLQIIEKFILKHKss------------------------lNSLQMIKLWKGLYYCLWLADKVP 64  
Q5CR59         13 MRLSKTLTSISPASRKKGLDIITRYISKHNns------------------------mTRLQMLKIWKGLYYSMWLSDKVL 68   Cryptosporidi...
ESS32435       50 VAMARLLAHTDVKYRNRGLKRVEAFLSGVSrrrrakqaegvcevnaaerkaasspL-PFSQYEKVWTTLYYAAWLSDKPL 128 
Q8I2K4         13 EKIFVELCHVEKENRDKGIDILYDYITKNRkc------------------------lNEHKITYICKGLFYYYWLCYSME 68   Plasmodium fa...
EDL42348       17 ELLFVDLCHVNKEKRDTGIKALTDYIKKKKvp------------------------lDGQHLAYICKGLFYYYWLCYSLE 72  
XP_001611825    7 QKLCHMLASCEESTRSQALNSISELFSEVTc------------------------LvDELTLLKLTKALYFMLWLTDKPL 62  
Q4U973          7 RSICHNLANTDSNLRKRAIRSVRELFKKNPn------------------------L-DDLSLSKICKGLYYCLWMSDDPI 61   Theileria ann...
CCF50301      101 IQQRLANDLAQLVLVHP-ScstsftsstcttspgeeggmseraLAGLKFLEAFWDTIVSEWGALDKHRIDKFYLLVRRFV 179 
XP_649440      64 YQEKVRKEITSIMNKeei-----------------------dkHECILFVKVGMETLERYWDEIDYVRIKKYEMLLCQMI 120 
Q236Y1         77 VQQALADELANLIFSVNkQk----------------------fEAINMWFQACFNIMNKEWAKIDYWRVNKFSSLMRKVI 134  Tetrahymena t...
XP_002140253   65 IQREIAINISKFQRLFAsV------------------------ELWNSFIYEFYNMLTQRWDIIDRLRMDKFMFLQRVMI 120 
Q5CR59         69 IQREIAVNISQLQKRFEvK------------------------EYLFSFIEEFYLMMRFRWDGMDHYRMDKFTFLQRTML 124  Cryptosporidi...
ESS32435      129 VQRELFVCLALLERILPtF------------------------AEKRKFFKAFFLVMKSNWDKLDCIRVNKFLLLEKIMV 184 
Q8I2K4         69 EQKKCSLKICRLIHKFNsKnnk-------------------kkKNVFLFVQCFLQVMSNKYDNLDIHRLNKYLFLFRVFQ 129  Plasmodium fa...
EDL42348       73 EQKTAACKISKILRNIDeVdds------------------eekKSVFLFLQSFLMVMSSKYDSLDLYRLNKFLFLFRVFQ 134 
XP_001611825   63 KVRKVAVTIADSQSHFVdR------------------------RNRFAFFDALFKSMSMEWPNLDKNRVDKMLLFVRIVL 118 
Q4U973         62 QTRILSLDIIQLYKSIRlNssnlngvee------pllfdhnevDIRLRYLKCLMETVSREWLLLDKNRVDKVLLFTRIYV 135  Theileria ann...
CCF50301      180 ASGFQLLAEEGwNL-DAT----RRFAQ-ILGKFqg---------gVLstn-------dpkVP----------DSLTYHLS 227 
XP_649440     121 QKYLYFISQHGwNI-EMI----KEWNEyLLEHVvplqn------------------------------npisLSFSTKVA 165 
Q236Y1        135 TAFIRYLRKKGyNT-DYVrqfsKSVHDeFYVEQtq-----------------------------------tvSGLALHIM 178  Tetrahymena t...
XP_002140253  121 AESLDIIKKSEyDK-VYIehllNTYKMcIFTts--------------------------------------sIGISLIFC 161 
Q5CR59        125 AESLNLLSKKNfDP-EFAkgllDVYRRcLFVENidnensigkkrkFLmisdhigsgdevdPSinsysnrstgIGVSLIFC 203  Cryptosporidi...
ESS32435      185 AELMHLSFQVAhRPhKFVypmgRFLAErILLDErg------------------------------------gNGLAHQLG 228 
Q8I2K4        130 AEILMFFHINAwNN-LYLkkynKIFLQ-YFDDT---------------------------------------SELYYNYI 168  Plasmodium fa...
EDL42348      135 AEFLLFLHRHSwRS-YYIrrynQIMVR-MFDDT---------------------------------------NDVYYNHI 173 
XP_001611825  119 AALLELLNNGKwDL-NEI----NRFNDiVLNKEgifh--------------------------------krsAGLAFQFI 161 
Q4U973        136 SEILYYMHELNwDL-LVL----NKLSEiFLNKNifg---------------------------------rdtLGLLVHVI 177  Theileria ann...
CCF50301      228 DIYLDELEK-VIEQVDNSQNEEekqeqeqeeqeqeeqeqeeqeqeeqeqeeqeqeeqeqeeqedlpliptlELLKPFVDA 306 
XP_649440     166 DYYYDYLNDvIYIDEAPEPNEEak----------------------------------------------nELARLLIKY 199 
Q236Y1        179 QIFPEVLSHfTSAKHDQVC----------------------------------------------------LFLDIFLKQ 206  Tetrahymena t...
XP_002140253  162 HQFPQEFVY-FLNSQFSEKKCNyersni--------------------------------------nvlfeLIAELFVNI 202 
Q5CR59        204 KQFPQESVY--------------------------------------------------------------LLYEQYKLI 221  Cryptosporidi...
ESS32435      229 LYFLLEFREvRARVTASDASVAsdqdatdsddgddasl------------------tatgeqessrdalffAFFFPFFYA 290 
Q8I2K4        169 DTFIKEFLGnEYFLKSKKQEQRnynt-----------------------------------------kqflLLIDPFFKI 207  Plasmodium fa...
EDL42348      174 DTFFKEFFGnQFYLKAKDQNEKvhik------------------------------------------nflLLMDFFFKI 211 
XP_001611825  162 QVFFEEFEAnRVEFDKTNSWSElsai------------------------------------------gylHLMKPFLHL 199 
Q4U973        178 QVFTTELLYnYEQLKGSGEETKepptdsddnvnfneddsks-----------kinavhmnlcnnidsvkllYILKPFILM 246  Theileria ann...
CCF50301      307 LATAKSKAMYERIWSNVFR 325 
XP_649440     200 LKNGKIQSLHKSFEEARER 218 
Q236Y1        207 LNPNSCKGLRQKIKECIFE 225  Tetrahymena thermophila SB210
XP_002140253  203 IRDCNNRVVIKTIHEQLIR 221 
Q5CR59        222 KENPSNKNLLNEYISSFFI 240  Cryptosporidium parvum
ESS32435      291 ACFSQSPAMLRAIHTQVFL 309 
Q8I2K4        208 ICMTDQKYVMDLINKKVFL 226  Plasmodium falciparum 3D7
EDL42348      212 ICKTEKKHIIDVIRNKIFS 230 
XP_001611825  200 TLLNDNRHLMKTLYMYVLS 218 
Q4U973        247 FVTSKDSLLLKTIYDYIFK 265  Theileria annulata
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