Conserved Protein Domain Family
DUF4302

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pfam14135: DUF4302 
Domain of unknown function (DUF4302)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 344 and 443 amino acids in length. There are two completely conserved residues (R and L) that may be functionally important.
Statistics
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PSSM-Id: 433743
Aligned: 43 rows
Threshold Bit Score: 147.9
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013996486                 24 SPSQRNLQNINELRKELTEAPYGWKVMYFSkTDSlafsnkdevfkkeifyyrdqYGYGGHYFLMKFtPEGKVTMLADFd- 102 ...
Q8A2R9                       31 SSAQRAIASVNECQEILKGAANGWLLEYYT-GED--------------------GEYGGFNVLARF-DGNNVIMAADFat 88  ...
CDC01148                     31 SSADRENASVLELKSLLTSSTNGWKLEYRY-GNE--------------------GRGGAANLFFKF-DANEVTIASDYat 88 
CDD83827                     35 SAANRLTENINRYERILQGVPNGWLMEYYI-GSN--------------------YEYGGIPILCRF-KDGRVEMATTFea 92 
Q8A2R2                       32 SSANRATEEVKQYSELLESASNGWRMEYYI-GQD--------------------YALGGITLLCKF-DGQRVTMASQG-- 87  ...
faib:Ccan_20100              31 PANQRVSEAIQEYRQILKSAEHGWGFEYYTkGNE--------------------RSNGGYNFQVSF-TDTDVTASLLG-- 87 
CCZ12225                     32 SSSKRLQKALDEARTVLRSSEKGWVMDYYV-GDD--------------------SSNGGYAFTVKF-DSLTVTASSEL-- 87 
CDD20234                     32 SASERIDAAVAHDKEVLESATNGWKLVYYT-GEE--------------------YTGGGYTYLCKF-KNGNAIVAGDM-- 87 
WGS:ACWZ:HMPREF0669_01419.1  31 STALRLDEAAKQSKELLESSETGWILNYYT-GRD--------------------YSNAGRTLLLKF-KDGKATIMGDL-- 86 
WP_009228596                 31 SASVRITNSIEEETRILESATNGWELHYYT-GKE--------------------YRFSGYTYLLKF-KDGKASVAADF-- 86  ...
WP_013996486                103 -aNSSSKPQE--SQFEIKQNTFTELSFTTYN-YIHQLVNEQLE----------GKSDFLYLrKDFDQNLLFKTTNSIEpa 168 ...
Q8A2R9                       89 dnYEIGEEST--SLYKVESYQGTELSFDSYNeLIHEFCEPSGYnsp----gyaGDYEFVFR-SVSKEKIVLTGKKHGV-- 159 ...
CDC01148                     89 ssYSPGQTAT--SLYTVQSYNGTEISFDSYNeILHAFCEPNGYndp----glmGDYEFIVR-SMSENEIHLAGKKYGV-- 159
CDD83827                     93 dgVKPGTVVT--SLYKLGSNQSTVLSFDTYNpLIHYFGTPGLVdisnpnttlgGDYEFVMReGA-GDKIVMEGTKYGN-- 167
Q8A2R2                       88 --YEGDETIS--SLYKVVSEEATMLTFDTYNaFIHAYAKPQGGgsnpn-anlqGDYEFIIKeAS-AEKIVMQGKKYGN-- 159 ...
faib:Ccan_20100              88 ----FTGQKT--SNYDIIPNGGPTLTFDQYNdVLHYFTVPDQDryq----adlAEYEFLIL-SYESNVVTLKGKKYGS-- 154
CCZ12225                     88 ----TKGAST--SYYKLTTDNGPVLTFDTYNdVFHALATPSAGnye----gnhADYEFQIV-SATSDLVVLRGRRTNN-- 154
CDD20234                     88 ----SDGYQEakSSYDIITDQSVVLTFNTFNeLMHKFATPTSSsid----geqGDYEFLIQ-KVTNDSIYLEGKKWGN-- 156
WGS:ACWZ:HMPREF0669_01419.1  87 ----TGPEVTskSDYDVVKDQGIVLTFNTNNeVLHSLTQAALRepe----gkqGDYEFLIL-KQTQDSIYLRGKRWHN-- 155
WP_009228596                 87 --VGSDSIST--SRYELKRDQGPVLTFTTFNaIMHEKAQVSLEnvn----geeGDYEFLIL-KATADTIHLKGKKWGN-- 155 ...
WP_013996486                169 reYIVFEKLKSEEAWKHPSENNVQKAfENRAffakmknpqivirkG-SRVFFQSDVVIKT--TTGTpeynrflksmtanr 245 ...
Q8A2R9                      160 --TLIMTPLPAETNWQEKLTNIANVVsQASY--------------VtYKLIVNGQEITKMgqEEHAfsvt---------- 213 ...
CDC01148                    160 --EMVMTRLDDTVDWTTYLAAAAQISeDSDY--------------NlFSLMQGDQKVASVmrEDRAfllg---------- 213
CDD83827                    168 --RMVLTPLLEDADWKSYISGALQIEdAAFL--------------KnFKIMDQAKELGSLsrSNWTfs------------ 219
Q8A2R2                      160 --TIVMYALPDDLNWEAYINSVNDVEeNAFF--------------IqYQLLVDGNLVGMTqrSNYTfvi----------- 212 ...
faib:Ccan_20100             155 --LARLVKLQ-NANYLQEVDVVRKYVkNGFKsltiegkttefstpTrYNVAFK--------------------------- 204
CCZ12225                    155 --YVYLRPLT--TTPEEYLAKVADTEkKFVV--------------AsLSTDVDGKNVSADldINNRqas----------- 205
CDD20234                    157 --KMVMTRMPENLSWEEHLDSITRVAnDIRY----------------NNKVMNGNDSIGYisLDDYtrr----------- 207
WGS:ACWZ:HMPREF0669_01419.1 156 --NMVLTKLPKDTKWEEYMTGALTVK-ESLAv-------------NtFKFILG-NDTIADgtIDPTstr----------- 207
WP_009228596                156 --HMYLTRLADNVNWKEHLDSIISVS-SGVS--------------NnYEISVGESDATGSasLNTLtqh----------- 207 ...
WP_013996486                246 yyvflagkkwnsnpnitVPDESYALGSGYVGTEQGITFRTGIRYdKNYIFYDFERKG 302 Capnocytophaga canimorsus
Q8A2R9                      214 --------------kvdETGETTVSLYPFIYTEEGIKMYEPLVV-NGVEINNFKWDN 255 Bacteroides thetaiotaom...
CDC01148                    214 --------------svdENGTPPYAYFPFVCTETGVRTLEPMVC-NGISMQNFTWDN 255
CDD83827                    220 ---------------yrPEGSKEKINVPFVYTSTGLKLREPMEV-NGVKVMNFTWNS 260
Q8A2R2                      213 --------------aynDGGNIVQEQSPFLFTTDGFRFREPVSL-AGVTVQNFVWDP 254 Bacteroides thetaiotaom...
faib:Ccan_20100             205 -----------------DVQTGKELKEAFVLTPEGIRFYEAVKI-NGVTFQEMVLNT 243
CCZ12225                    206 --------------fysTTDSTFSKSCAFTFTDTGIRLSSAVDA-YGKTLSDFSFEP 247
CDD20234                    208 ---------------avLEAGNDKADVPYFVTSKGVRFQSPITV-DGQEISEMKYDE 248
WGS:ACWZ:HMPREF0669_01419.1 208 ---------------lnAEIKGITYDMPFTFTNKGIHLQRPLVV-NGVSYSDLTWNA 248
WP_009228596                208 ---------------anIKVGNNSYSCAYSTTTTGIELAQPITI-EGKEYNSFTLNN 248 Prevotella sp. oral tax...
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