Conserved Protein Domain Family
PRK04270

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PRK04270: PRK04270 
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
Links
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Statistics
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PSSM-Id: 179806
Aligned: 66 rows
Threshold Bit Score: 393.454
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
110668665   1 MTESPRLRESPDNRSLADICNFGVVNLDKPVGPSAHQVSAWVRDLIG-----------------VERAAHAGTLDPKVTG 63 
292656614   1 -----MLRDPPEHRSVGDLLSFGVVNLDKPPGPSAHQVTGWVRDMAD-----------------VDRAAHSGTLDPKVTG 58 
13541183    1 -------------MIEEIQKLNGFIVIDKPQGPTSHQVDYWVRQILG-----------------TEKVGHIGTLDPNVTG 50 
161760539   1 ---------------MDFSNINGFVVLDKPQGPTSHQVDHWVREILG-----------------IEKVAHIGTLDPNVTG 48 
222480224  26 GDAVDPLRSPPDQRSVPELLRFGVVNVDKPAGPSSHQLSAWVRDAINetlatl-----dpdgspIHGVAHAGTLDPKVTG 100
289579959   1 MSQRQRLRPAPGDRTPAELLQFGVVNLDKPPGPSSHQVSGWLRDAVAdalaeadqsedsdtsptIDQAAHAGTLDPKVTG 80 
76803088    1 ----MRERGPPADRDPETLLEFGVINLDKPPGPSAHQVAAWVRDMAG-----------------VEQAAHAGTLDPKVTG 59 
284165530   1 MADRSRLRGPPEDRTPAELLTFGVVNLDKPPGPSSHQVSGWLRDAVDetladr------apdatIEQAAHAGTLDPKVTG 74 
257053389   1 ----MALRGPPEDRSPAELLSFGVLNLDKPPGPSAHQVAAWVRDLAT-----------------VERAAHAGTLDPKVTG 59 
257387781   1 -----MVRDSPEHRSPADLLTFGVVNLDKPPGPSAHQVAAWVRDAVDdaldaa------gddrtLGRVAHGGTLDPKVTG 69 
110668665  64 CLPILLGEATRLAPVFLEGTKEYLAVLEFHGPPP--SDLSMIIETFEGTIYQKPPRKSAVSRRLRKRTIETLDILEVDSd 141
292656614  59 CLPTLLGDATRMAQVFLEGSKEYVSVLELHGPAS--ADIDSTVAEFESKLYQKPPRKSAVSRRLRVREIHDLDLLEVKD- 135
13541183   51 VLVMAIGKAVRLIDVVHEKPKEYVGVMRFHSDISe-EEVREVFRKFTTRIYQLPPVRSAVSRKVRIKTIYELDMIEKKD- 128
161760539  49 VLTMAIGKAVRLVDVVHESPKEYVGVMRFYEDITe-EEVRYYFKKFTGRIYQLPPVRSAVARSLRIKTVYSLDLLEKKD- 126
222480224 101 CLPTLTGDATRAAQVFLEGSKEYVSVLELHGSPP--ADFRDVVAEFEAEIYQKPPRKSAVTRRLRTRTIYDLDVLEVDD- 177
289579959  81 CLPTMLGDATRLAQVFLEGHKEYVAVLECHGSIP--ADVESTVAEFEGPIYQKPPRKSAVSRRLRVREIYELDVLEQGD- 157
76803088   60 CLPVLTGTATRAAQVFDESRKGYVAVLELHGTAP--SDLESTVAEFEGPLYQKPPRKSAVARRLRTRTVHRLDVLESEA- 136
284165530  75 CLPVMLGEATRLAQVFLEGHKEYVAVLECHAPVP--ADAESVVAEFEGPIYQKPPRKSAVARRLRVREIYDLEVLETDE- 151
257053389  60 CLPMLLGDATRMAQVFDDSDKEYVAVLELHERLAdpSTLEAVADEFEGEIYQKPPKKSAVVRRLRSREIHRLDVLEAED- 138
257387781  70 CLPILLGDAARAARVFDDAVKEYVTILELHDQAP--PDFDSIVAEFEGEIYQKPPRKSAVKRRLRSRTIHALDVLERHD- 146
110668665 142 aQQALLRIRCESGTYIRKLCHDLGLAAGTGAHMGDLRRTGTTPFSDTNLISTADLTDAVVFTLEEivranqtqindapdd 221
292656614 136 -RQALLRIRCESGTYIRKLCHDLGLALGTGGHMGHLRRTATDPFDDADLATLHDLKDALAFAAE---------------- 198
13541183  129 -KIVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRISTGPFKEDIAITLQDLQAYVDLAKE---------------- 191
161760539 127 -RLVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRTSTGPFSEDRCITLQDFAAMVELARK---------------- 189
222480224 178 -RQALLRIRCESGTYIRKLCHDIGLATGVGAHMGHLRRTATDPFDDRDLHPLQDLVDGLT-WAEE--------------- 240
289579959 158 -RQLLLRIRCESGTYVRKLCHDLGLALGTGGHMGHLRRTATSPFDDTDLYTATEFLDALAFWLED--------------- 221
76803088  137 -RRVLLSVECESGTYIRKLCHDIGLAVGTGGHMGPLRRTKTGGFDDRTLVTFEDFADGLAFWRDH--------------- 200
284165530 152 -RRLLLRIRCESGTYVRKLCHDLGLALGTGGHMGHLRRTATSPFDDRDLHSAHDFLDALAYWRED--------------- 215
257053389 139 -RRALLSIRCESGTYIRKLCHDMGLALGTGAHMGDLRRAATDPFDDADLVTMHDFVDALAWWRED--------------- 202
257387781 147 -RRALLRVRCGSGTYVRKLCHDIGLALGTGAHMGELRRTATGDFDDRDLVTMEDLVDALAEWTDN--------------- 210
110668665 222 staaysllhkintANIDpnstsptdHLRNVISPAERALQHLPTVIIAPSAAAEVAMGAPVYAPGVI---EF--DSAAGNT 296
292656614 199 -------------GDES--------WLRDVVSPAERALSHLPSVTIANSAAREVANGAPVYAPGVF---DV--DADAARG 252
13541183  192 -------------GKDE--------LFRSHFLDMTYAFIDYPKIVAKKSAVENIAHGSDLYVGGVK---LI--DGNFQKG 245
161760539 190 -------------GEDK--------LLRDHILDMTYAFKDYPKIVVKRSAMRNIAHGSDLYAGGIK---II--DGKFRKG 243
222480224 241 -------------GDDA--------FLREVVRPAEDALVHLPSVTIAPSAARNVATGAPVYAPGVIdvdSVseGGEGDDG 299
289579959 222 -------------DDPS--------LLYDIVDPAERILEEIPHLVIDSTAAREVAEGAPVYAPGVR---KVvaDTALERG 277
76803088  201 -------------DDPE--------LLCDVVAPAERALEGLPRLTVAFSAASEIANGAPVYAPGVL---AHe-LDGADEG 255
284165530 216 -------------GDPE--------VLLDVVDPAERILEGLPGVVIAPSAAREVANGAPVYDPGVL---EV--DDEARAG 269
257053389 203 -------------DDPD--------PLREVVQPAERALVDLPSVTIAPSAAESVAEGAPIYAPGVI---DA--DDDLDPA 256
257387781 211 -------------DDET--------WLHETVAPAERALAGYPTVTIAPSAAREVAHGAPVYAPGVI-------ETDAEQG 262
110668665 297 Hdit-dsaLVSCHTPDETAVCLGRVSGPLD----AESGEVISLERVLV 339
292656614 253 D-------LVACFTDDGSAVCLGELVGDAD----ADSGEVVSLEAVLV 289
13541183  246 D-------RVCVLSEDNELLGTGIARCDSSnlfmK----VVDFDHIFV 282
161760539 244 E-------RVAVISEDNDLVGTGIAMCSSDnifmK----VVDFDHIFL 280
222480224 300 DdtdrdppLVACHTPDGAAVCLGRLVGDPD----AESGVVVSLERVLV 343
289579959 278 D-------LVACYTQVGSAVCLGKMVGDPD----AESGVVVDLERVLV 314
76803088  256 S-------LVACYTPDGAAVCLGWLVGDPD----AADGTVAELERVLV 292
284165530 270 E-------LVACYTPNGAAVCLGEFVDDA------SRDVTVDLERVLV 304
257053389 257 Ae-----pLVACYIPNGAAVCLGTLAGDPD----ADEGTVVELERVLV 295
257387781 263 A-------DVCCVTPDGAAVCLGRLVGDPD----ADSGVAVELERVLV 299
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