Conserved Protein Domain Family
ThrE

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pfam06738: ThrE 
Putative threonine/serine exporter
ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.
Statistics
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PSSM-Id: 461997
Aligned: 114 rows
Threshold Bit Score: 118.009
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAK41684               415 IMQLCRALMRYGAPTHRLEEYMQMTARVLEV-EGQFLYLPGCMIMSFdD-------PATrTAEvklVrVVQGV-DLGRLA 485 
O26844                   9 LEELSRALIASGNSVTDTERILWSVAESQGV-EVEVSVLPTMIIIK----------AEGeVSRmglAaQSPGMmPLHQVT 77   Meth...
Q6AD60                  36 LVQLGGALLSIGMASTDIQNTLKRVATALGSpKAAIFVFPTLMAVGMp--------GKQqTRFevaVpSGEEM-RFDRAS 106  Leif...
PRJNA261003:LJ00_19065  13 ITRLGAAMGAAHYPVSLIRQMLDRASSAYGV-RNDFIALPNYVQVVGp--------TGAhGTIveaAhLDHEL-RFAQMF 82  
Q09B83                  21 ILRLGKALHQYGTPAHRLEEQLRQVSERFGV-EARFFSTPTSIFASFgTpe---llQTSlIRV-----EPGEI-DLERLT 90   Stig...
Q55DN3                 511 LMELGRALTMSGVPSNRLEFELTLISTTFGI-DGHFFTTPTGIFFSFgSphsilspYTHfLRI-----NSTDY-NMERMV 583  Dict...
Q54Q20                 526 LMELGRALLMSGVPAHRLEYELTLISGTFGI-DGHFFTTPTGIFFSFgSphtilspYTHfLRI-----NSTDY-NMNRLI 598  Dict...
Q088Q8                  13 IIKLGKYLHKFGTPAYRLESHLQTVCNTLGI-EGYFLISPTSMTFVLqHdte--qeYNHvARV-----KPGDL-DLGSLA 83   Shew...
Q8EJZ8                  13 IIKLGKALHKFGTPAYRLETHLQTVSRTLGI-EGYFLISPTSMTFVLqHdtd--qeYNH-VAR---V-KPGEL-DLGSLA 83   Shew...
Q7UJS3                   1 -MELARSLHACGSPAYELDLEMEQVSASLGH-EASFFSTPTALFVTFgGd------ETRlLRV-----YPSDT-NLGRYA 66   Pire...
CAK41684               486 ETHNVYKNVVHDMIGVEEAIQELDLIMKRPPrFNKWILVVTYGLASVAVGPFAfDARPIDMPIIFFLGCLVGFMQHVLaP 565 
O26844                  78 EIYRLTDDVTSRRMEVGEALGELRGILRGSHrFGRYGILLGYLILSIGIALLI-QPDPDLVIYSSFFSLIAGSLIVVG-Y 155  Meth...
Q6AD60                 107 SVYAVADRALTGTITATEGIKVLHAVEVAKPrFRGLVRVFGHGFAAAGVALVLlGAEVPTMLDALALGMLVGVVKLAV-R 185  Leif...
PRJNA261003:LJ00_19065  83 PLARLVRDAMRGAVRPDDGEAQLDRVLEMPDrFPGWVAVVGYGVQSAGLALVL-EPTALNLLVATVLGFLVGLFHVVV-Q 160 
Q09B83                  91 LLDALTYEVIHDKLSPELGTQRVEAILQAPPrYGLLVTLLCWTLAAGAAARLF-GGGPREMCVAGLSSLSIGVLDQVL-R 168  Stig...
Q55DN3                 584 RLERLADKVIYGEVSCVEALEKLRKILAKKPlYNIYLTTFSYIMSSFTIAFFF-DVGWVEVGACSIIGFYVGLLCLLS-S 661  Dict...
Q54Q20                 599 LLEQLADQVIYGHVSCAEGLVRLKEILRLKPlYNNYLTVISFVLSSFAIAFFF-KAGWVEVGACSFVGLYVGLLSAVS-S 676  Dict...
Q088Q8                  84 RTFELVEELSSGQRTLQEALERLEEIANKPNpYGHKLTLLAFGSSAGAFAMLM-GTGWHDVFWSAIFGLLVYSLVFWA-E 161  Shew...
Q8EJZ8                  84 RTDELVDELTSGKRTLTEALDRLEEIANKPNpYGPVLTCFSFGTSAAAFAMLM-GTGWNDVFWSGLLGLLVYGFVYRA-E 161  Shew...
Q7UJS3                  67 ALFELQRAIQEEQMDVSEAWQRLTEINEMKDgYGPAIHIASHGGVAACISVLV-GGGGMVVLSAGVIGLIVGTFVVWL-T 144  Pire...
CAK41684               566 RSVLYSNVFEVTAAILTSFLARAFGS-IYatvDGTherlFcfSALAQSSIALILPGFMVLCSSLELQSHQMIAGSIRMVY 644 
O26844                 156 GNRRLSLIMPVLASFTVSGVA-------Ff--LINtgavSgnLTLLVPPLIYFIPGVTLTTGIYELASGELVSGSSRVIY 226  Meth...
Q6AD60                 186 PKTHAAILFPVATAFLLALLIFSLGKtviv---------gapLQALIPPLVTLLPGAVLTTGAWELAAGDTIAGASRLVS 256  Leif...
PRJNA261003:LJ00_19065 161 RAGMLQHLLPAVSAFTVTAICLLGAHrlgm--------dhvnLRALIPPLAMFLPGAAITLAVVELTARDVISGTSRLIA 232 
Q09B83                 169 RGSRAARVLESAAALLSSVLAVAAASifgp---------lsvQVATLSGLIVLLPGLGLTVAINELATRNLISGTSRLTG 239  Stig...
Q55DN3                 662 KVSLVGRVLEALSSCGGAIIASLFNCyisp---------ipiFTVTLGGIISLLPGLGLTLAVAEISTRNLVSGTSRLVG 732  Dict...
Q54Q20                 677 KYATVGRVLEALSACGGAVLASLFNAfiyp---------vhiFMVTLGGIIALAPGLSLTLAVAEISTRNLISGNARLVG 747  Dict...
Q088Q8                 162 RSKRIAEMLEPMAAVVCAILASGIAQldps---------inlPVTILSGIIIFVPGLALTLGLAELAARDLISGTARIMD 232  Shew...
Q8EJZ8                 162 RSSRMAEVLEPFATIVCAIVACAIARiDP---NIN----I--PVVILSSIIIFIPGLALTLGLAELAARDLISGTARIMD 232  Shew...
Q7UJS3                 145 HLRHQVHLINVVAGFIASSIACGIQAfvgp---------gnfELTSLAALILLVPGLHLTISINELATQNLASGSARFAG 215  Pire...
CAK41684               645 SIIYSMFLGYGITVGTTI 662 
O26844                 227 GCMVLLLLLFGVLMGMQL 244  Methanothermobacter thermautotrophicus str. Delta H
Q6AD60                 257 GIVQLGFLATGILAAMTI 274  Leifsonia xyli subsp. xyli
PRJNA261003:LJ00_19065 233 GFVQIAQLAFGILIATQF 250 
Q09B83                 240 AVLVFLQLTFGVALGgrl 257  Stigmatella aurantiaca DW4/3-1
Q55DN3                 733 VFSCLLQLTFGIALGTKF 750  Dictyostelium discoideum AX4
Q54Q20                 748 VFSCLLQLTFGIALGTRI 765  Dictyostelium discoideum AX4
Q088Q8                 233 AVMQLFKLYFGAVLGMTI 250  Shewanella frigidimarina NCIMB 400
Q8EJZ8                 233 ASMLLFKLYFGAVLGMAI 250  Shewanella oneidensis
Q7UJS3                 216 AMTTLLTIVFGVSMGYGL 233  Pirellula sp.
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