3M3H


Conserved Protein Domain Family
PyrE

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COG0461: PyrE 
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]
Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Statistics
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PSSM-Id: 440229
Aligned: 956 rows
Threshold Bit Score: 84.05
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
COG0461 is the only member of the superfamily cl43147
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3M3H_A        23 NAmKKEIASHLLEIGAVFLqpnDpFTWSSGMKSPIYCDNRLTLSYPKVRQTIAAGLEELIKehfpTVEVIAGTATAGIAH 102
ADM28202       1 ---MSWLAIELYRKGMVKI---GqFKLSSGLESPFYIDLRRLYSYPELMENIINMALNTINl--dEYDGITGIATSGLVL 72 
AFH42274       1 ---MSGIAVEFLKNGIIKI---GkFKLTSGIESPFYIDLRRLYSFPSLREKVVEEIVKRFPt--dQADVIVGIATSGIAL 72 
WP_083756882  46 CYiKSYLARRIQECGLVKR---GtFILSSGKRSDVYVDMRKLWSFPKLARLAALLMSALIRsk-vEYATIVGVATGGIPL 121
WP_012308812   1 MD-AHELGIILISRGMLKF---GeFTLTSGKKSNIYVDLRPLPSFPEEFMKIATEMSKRMNg---DF-GICGVAVGGLPL 72 
WP_012608144   1 ---MSWISIELYKRGMVKI---GrFKLSSGIESPFYIDMRRLYMYPDLARMIILELTRRVKl--dDIDVVVGVATAGIPL 72 
WP_013142557   4 ESvLEEIVIDLYRNKLFKI---GeYRLTSGKISPYYIDLRILPSYYDIYSRIIDISISKLKp--lKFDIVVGIESAGIIH 78 
WP_014737743   1 ---MSWIAADLYRRGMVKL---GlFKLTSGLESPFYIDLRRLYSYPELAVRVVERALSTVPf--hGVEVVAGVETAGIPL 72 
WP_020963041   1 -----MIEEILWQIGAVKT---GeFRLTSGKISNIYVDLRKLPSYPEAFRRVVQLMTEKARq--ySFDYVCGIAVGGLPL 70 
WP_126449264   1 ----MGLAQVLLDRKMLLI---GnFVLTSGKMSPYYLDLRRFPSYPEFEK-FVDAAVKRAQt--lKVDVIVGVATGGLPL 70 
3M3H_A       103 AAWVSDRMDLPMCYVRSKAKGHGKGNQIEgkaeKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYElEAGK 182
ADM28202      73 ASFIACRTKKPLSYVRLERKEYGTKSLVEgd-vVSKKILIVDDVATTGSSIEYAYLAVKEQGGNPIGVFVVIDRE-QGAR 150
AFH42274      73 ASFIGCKTGKPIAYVRLDRKEHGTQALLEge-vRNKKAVVVDDVATTGGSLEHAISAVKEMGGNVMFSVVVVDRE-QGAR 150
WP_083756882 122 AAHLSVTLGWPMGYARPKRKEHGQMRLVEgv-ePGQKVVVVDDVTTTGGSLAKTIDALRDFGAEPVLAAALLDRE-EGSV 199
WP_012308812  73 ATAVAIISRRPLIYVRKEKKEHGTESLLEgs-lNMRSYVIIDDVATTGGSILNAARIVRNYGPDVKEAWVVVDRM-QGAA 150
WP_012608144  73 ATYVSCLTNKPMAYVRVEKKNHGTSSLIEgd-vTGLRTLILDDVSTTGSSILKAVEAILEAGGIPVRVAVLVDRE-QGAR 150
WP_013142557  79 ASFIACRTRKPVGYVRKKPKQHGTRRLVEgi-vTGKKVLVVDDVATTGGSLEHAVNAVRSEGGTVEKAFVFIDRQ-EGAR 156
WP_014737743  73 AAFLACRTGLAMAYVRKNRKNHATGQAVEgd-vANKRVMVVDDVVTTGGTLLRSIDYLREAGAAVVRALVVVDRE-QGAR 150
WP_020963041  71 ATAIAYEMSKPLIYARREKKTHGTMKQLEgdyvKGSKILLIDDVATTGGTLIDIIGLLRGEGLEVIKALVVVDRG-EGAR 149
WP_126449264  71 ASFMACRTGTPLAYVRLEKKGHGTDRVLEgd-vSGRDALIVDDVATTGSSLERAIVEVAKEGGKPRAALVLVDRQ-EGAR 148
3M3H_A       183 EKLEAANVASYSLSDYSALTEVAAEKGIIGQ 213
ADM28202     151 ERLGRYGLRFYSLLTARELFDILRNEGYIDE 181
AFH42274     151 EKLKSIGVELYSLFTAKELFKELYESNTIDE 181
WP_083756882 200 EEIEKRGVEFIRLLTLNQVLRGLRCE----- 225
WP_012308812 151 ESLKEEGIELKSLATLPDIVKLVLDSl--pE 179
WP_012608144 151 EVLASRGIELFRLITAREVFRDLYAHGLINE 181
WP_013142557 157 ERLRRLGVELVSLMNTWFIINVLVKHRIIDE 187
WP_014737743 151 QLLTRHGVEFYALTTAREIFEALWREGLIAH 181
WP_020963041 150 EALQNIGVSLDSLTTLESILRAKK------- 173
WP_126449264 149 KRLENYGVSLLAVATISDLLNELINSGALTA 179
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