2DER


Conserved Protein Domain Family
MnmA

?
COG0482: MnmA 
tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]
tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain is part of the Pathway/BioSystem: tRNA modification
Statistics
?
PSSM-Id: 440250
Aligned: 749 rows
Threshold Bit Score: 301.973
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2DER_A        18 KKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD-----------------------------G---EEYCTAAA 65 
WP_010936512   6 ELIMVAMSGGVDSSVAAMLLLEQGYDVAGVSLQLKSNNE-----------------------------P---YGNGYNLK 53 
NP_711668      4 GKIIVAMSGGVDSAVTAGLLMEDGYEVIGVNLRTWEYEApac------------------------dtT---KKSCCSPE 56 
WP_013253490   7 DAVVIALSGGVDSSVAAWMLSRQSGRIFGATHYIQDDS------------------------------------PCCNTK 50 
WP_014244514  12 QTILVGMDGGVESTVAAYLLKKQGLNVVGLGVVFHEYSY-----------------------------K---SLSVWTPK 59 
WP_041948407   1 mRVLCAMSGGVDSAVSAFLLKQQGHEVIGANMRFWEYKEplplsppldkgrgaeggvgscetpvlvknK---LTSCCSPE 77 
WP_014962177   3 SRVLVGLSGGVDSTVAALLLKEAGFDVYGAIVEIWSENSsggrs-------------------geereKpwfERACCHLP 63 
WP_083222112   6 KKVVVGMSGGVDSSVAAYLLKRDGYDVVGVMLKLWAEEGg---------------------------tR---DNACCSLA 55 
WP_102243522   8 KTVLIAMTGGVESTVAAYLLKKQGYRCIGVGLQLFADGEe---------------------------sG---PFADVAVL 57 
WP_087862455   5 KHVYVALSGGVDSAVAAVRLLEAGYRVTAIFMQTWHDPHa-------------------------------rTVADSELE 53 
2DER_A        66 DLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAaEDLGA----------DY 135
WP_010936512  54 LINRAREVAAALGIPHYVVDLSDIFSQRVIADFCQQYSQGRTPNPCIRCNYYVKIGALLEKI-PDFNA----------GY 122
NP_711668     57 DIRDARDVGISLKIPFYVIKMEKVFQEKVIDRFIEDYQHGKTPNPCVECNTFVKFGALFEKA-KALGI----------DK 125
WP_013253490  51 TIYRARVICRDLGIPYRLLDMRSSFRQSVVDPFVETYRRAETPNPCVRCNERLRFGDFYHQV-RRLLVeegalreterPR 129
WP_014244514  60 SLENIKKICNQLEIPFYGTNINSLFYSRVLEPVVSTRLAAEQFEPVIAWNKIL-IETLIEKA-KVVGA----------TG 127
WP_041948407  78 DMADAERSARGMGIPFYALKMEADFRVNVIDPFVADYENGLTPNPCVHCNTYIKFGEFYEKA-TALGF----------DQ 146
WP_014962177  64 MVK--FLCEEYLHIPYVQIDQKQNFQEKIVDVFREGYHNGVTPNPCTDCNAEIKIKTLIDWA-EQQKI----------SY 130
WP_083222112  56 SVNDARRVAASIGIPFYLLDAAPSFYEKVVVPFIEAYLRGETPNPCADCNPLVRWRWLLNYA-NLIGA----------KY 124
WP_102243522  58 DLNKIKGICNYLDIPFYAVNAADIFTDKVLDPLVGRVLSGQTFEPLVFLNSVL-LDVLLEKA-KKFQT----------TL 125
WP_087862455  54 QAEVAASTAKKIGVPFICLDVREKFYRVVIRSFIEQYLSGLTPNPCLFCNPQIKWGLLQEYA-LDQGA----------DY 122
2DER_A       136 IATGHYVRRAD--VDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVT-----AKKKDST 208
WP_010936512 123 LATGHYARVLS--DENGTHLLKGADEKKDQSYFLYTLPPESLSRLIFPLGKRYKKDIIRLADKMKLP------VSQKESQ 194
NP_711668    126 IATGHYARIAR--NGERYAIANGIDVGKNQAYYLYGLSQENLKNVIFPLGEMTKPEVRQIARRMGLPV-----ADKSESQ 198
WP_013253490 130 IATGHYARTAV--VDGVSYIRKGVDPSKDQSYMLYRIPRDVLPYVCFPLGEYTKKEVVEIALRENLPT-----KSIKESQ 202
WP_014244514 128 IATGHKAKVFKnqKSGVYSLLVPADVANDETYGLSRLSQDELSKLIFPLAEIKQNEILKIANLLGITFakddiENKKRRK 207
WP_041948407 147 IATGHYADIVHl-PNGRYAVAPAADRKKDQSYYLYGMSQESLARTIFPLAKMIKDEARRIAEANNIPV-----ARKPDSQ 220
WP_014962177 131 VATGHYAKNHYsvQNRLWGIAQALDRKKDQSYFLSRVPEHVLRKVLFPLGHWTKDKVREFARSKKIPV-----EEMVENM 205
WP_083222112 125 VATGHYARIRRd-GSGVPVLSRGADRRKDQSYVLSRIPIDALKRSLFPLGDLTKLEVRQIAKAAGLPS-----SEKKESQ 198
WP_102243522 126 VATAHYAKVLKnqKTGAFELMVANDLEFDQSYSLARLEQKHLENLILPLSEIRKKEVEKIGELIKVDF-----IPRIKSN 200
WP_087862455 123 FATGHYARLKPt-TNGKVELFRGFDRGKDQSYVLAMLSQHQLSRSLLPLGDLTKADVRRLAGALNLSV-----AGQKESQ 196
2DER_A       209 GICFIGERKFREFLGRYLpA----QP--GKIIT-VDGDEIGEHQGLMYHTLGQRKGL------GIGGtkegtEEP-WYVV 274
WP_010936512 195 DVCFIPDGDYKSFLATRMg----fTP--GKILD-KTGKILGEHQGLPLYTIGQRQGL------GLAS-----NEK-LFVS 255
NP_711668    199 EICFIPENDYRKFLEKKn-Ve--fTP--GFFKL-KDGRIVGKHKGRENFTIGQRKGL------GIAW-----KNP-LYVI 260
WP_013253490 203 DICFA-DGGYIDFLRHRLgTefvdRP--GDLVD-NSGKRLGQHRGYLHYTIGQRQGL------GLG------DGP-WYVS 265
WP_014244514 208 KSLFRT--DFIEVVERFs-AptlrKE--GRILSyRDGTTICEHDGVHLYHLNQ-EGIvg--kkGFAV-----DKT-LSVI 273
WP_041948407 221 EICFIPDNDHKAFLKREg-Vs--mRP--GYFRD-RLGAILGKHEGSVGLTIGQRKGL------GVAGf----AEA-QFVL 283
WP_014962177 206 EACFLSAKNVTSFLKREe-Ev--hSSgnWKVTD-MKGEKIGEIPTGIGLTKGQRKGI------GVAN-----AER-MYVK 269
WP_083222112 199 DICFIADGDYRAFLRRRAgGr--iRP--GAFVD-PAGKVLGEHDGLPFYTIGQRKGI------RIPG-----PEP-KYVL 261
WP_102243522 201 YKHIMHDPRMARLVEARs-SkdlrRT--GNIYDyVSDASICEHQGIHHYYVGQ-SGLvfdkksEIQi------dPlKQIV 270
WP_087862455 197 DLCFLRNEDYRAFLQRHApEa--aAP--GEIVN-LAGEVLGEHQGLAFYTIGQRRGI------RIAA-----SEP-YFVI 259
2DER_A       275 DKDVENNILVVAQGHEhprLMSVGLIAQQLH--WVDRe--P---F-T--GTMR--CTVKTRYRQTDIPCTVKAL-DD--- 338
WP_010936512 256 DMNPEANTIMVASHDQ---LYTSRILLSNFI--WRESr--I---P-L--DTPG--MIVKVRYKAAPAEVKKISQ-TG--- 316
NP_711668    261 SIE-DDGSVILGEENE---TYNESFSVIDLN--FQGLa--P---L-NegESLE--CRVQVRYRHIPIRCKITKM-K---- 321
WP_013253490 266 QIDGDANRVVVARKGE---FGTQRFSLSEVI--WDLPd--A---P-----PFE--CMVKIRYNSGEVPCRVEGLpES--- 325
WP_014244514 274 RINPRQQDVIVDNIER---YHYTHCRLMRFS----HDpamD---L-S--KPLQ--CFVQTKSSGAKLPCKLYFK-NN--- 334
WP_041948407 284 EI-LSNGDVILGPREE---LERRTFYIRDVV--FQGVa--EddrAwS--EGVP--CNVQIRYNGQPLAAVAYKV-ETplm 350
WP_014962177 270 KVDVHNKVVIMGSKKD---ILNRNFRIRDPLgpLF-----------Q--KKIKgnLYVKFRSVMEAVPC-I----EK--- 325
WP_083222112 262 RKNAQDQAITVGGRED---ALVERIRLRNVN--WLRSg--T---D-P--ADGK--IFAQPRYKSVPVGARFERQ-PD--- 322
WP_102243522 271 SIVPFKGNIFIDYPKR---LKHQQILVSGFL--PATNl--D---M-S--LPMS--CYVKMSPKGEKIPCRLFFK-NN--- 331
WP_087862455 260 DKDAQTNRLIVGYAKD---AGNKHLQTARSN--WISGl--P---P-E--EGGQ--YQVMIRYRANPVSAKLKEA-SM--- 320
2DER_A       339 DRIEVIFDEPVAAV-TP-GQSAVFY--N----G--E--V-CLGGGIIE--Q-R-----L 376
WP_010936512 317 DFYLLELASPVWAA-TP-GQAAVIY--L----G--D--M-VLGGGIIE--H-Ggdva-- 357
NP_711668    322 EGLIVHPLEDVRGV-TP-GQSAVFYplD----S--D--Y-LLLGGIIS--K-G-----S 361
WP_013253490 326 GSLLVELEEPa-SV-TP-GQSAVFY--R----D--D--L-VIGGGIID--R-------- 360
WP_014244514 335 RAVVVEFEDEQEGV-CPrGGYLVFY--NrraiG--A--T-VIGSGVVR--S-SgyfddE 382
WP_041948407 351 ASLRIELDTPAWAV-TP-GQAGVLY--D----R--DggF-ILAGGKIRl---Vpped-- 393
WP_014962177 326 GNLRFELLNENDGV-TP-GQIAAFY--D----D--E--QmVLGSGILEp-E-------E 364
WP_083222112 323 GSVLVQFSEPQPAI-AP-GQICALY--D----Ds-D--Q-VIASGTINliNlSi----- 364
WP_102243522 332 AQALVEFDNPREGLlVP-GQFLVFY--N----RehDkgK-VVGSGLVE--N-SgmfdeF 379
WP_087862455 321 DEFRLEFNQPLRGI-TP-GQFAVLY--Q----D--E--V-CLGGGIIK--R-Tw----- 358
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap